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Bovine Rumen Metabolome Database



Showing metabocard for Acetic acid (RMDB00042)

Legend: metabolite field enzyme field

Version 1.0
Creation Date 2005-11-16 15:48:42
Update Date 2009-05-29 10:14:57
Accession Number RMDB00042
Common Name Acetic acid
Description Acetic acid is one of the simplest carboxylic acids. It is an important chemical reagent and industrial chemical that is used in the production of plastic soft drink bottles, photographic film; and polyvinyl acetate for wood glue, as well as many synthetic fibres and fabrics. In households diluted acetic acid is often used as a cleaning agent. In the food industry acetic acid is used as an acidity regulator. The acetyl group, derived from acetic acid, is fundamental to the biochemistry of virtually all forms of life. When bound to coenzyme A it is central to the metabolism of carbohydrates and fats. However, the concentration of free acetic acid in cells is kept at a low level to avoid disrupting the control of the pH of the cell contents. Acetic acid is produced and excreted by certain bacteria, notably the Acetobacter genus and Clostridium acetobutylicum. These bacteria are found universally in foodstuffs, water, and soil, and acetic acid is produced naturally as fruits and some other foods spoil. Acetic acid is also a component of the vaginal lubrication of humans and other primates, where it appears to serve as a mild antibacterial agent.
Synonyms
  1. Acetate
  2. Ethanoate
  3. Ethanoic acid
  4. Ethylate
  5. Ethylic acid
  6. Glacial acetate
  7. Glacial acetic acid
  8. Kyselina octova
  9. Methanecarboxylate
  10. Methanecarboxylic acid
  11. Vinegar
  12. Vinegar acid
Chemical IUPAC Name acetic acid
Chemical Formula C2H4O2
Chemical Structure Structure
Chemical Taxonomy
Kingdom
  • Organic
Super Class
  • Organic acids
Class
  • Fatty Acids
Sub Class
  • Short chain fatty acids
Family
  • Mammalian_Metabolite
Species
  • carboxylic acid
Biofunction
  • Component of Glycerophospholipid metabolism; Component of Propanoate metabolism; Component of Pyruvate metabolism
Application
Source
  • Endogenous
Average Molecular Weight 60.052
Monoisotopic Molecular Weight 60.021130
Isomeric SMILES CC(O)=O
Canonical SMILES CC(O)=O
KEGG Compound ID C00033 Link Image
BioCyc ID ACET Link Image
BiGG ID 33590 Link Image
Wikipedia Link Acetic acid Link Image
METLIN ID 3206 Link Image
PubChem Compound 176 Link Image
PubChem Substance 11538534 Link Image
ChEBI ID 15366 Link Image
CAS Registry Number 64-19-7
InChI Identifier InChI=1/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
Synthesis Reference Law, David John. Process for the preparation of carboxylic acids and/or derivatives thereof. PCT Int. Appl. (2007), 14pp.
Melting Point (Experimental) 16.6 oC
Experimental Water Solubility 1000.0 mg/mL [MERCK INDEX (1996)] Source: PhysProp
Predicted Water Solubility 323.0 mg/mL [Predicted by ALOGPS] Calculated using ALOGPS
Physiological Charge -1
State Liquid
Experimental LogP/Hydrophobicity -0.17 [HANSCH,C ET AL. (1995)] Source: PhysProp
Predicted LogP/Hydrophobicity -0.12 [Predicted by ALOGPS]; -0.1 [Predicted by PubChem via XLOGP] Calculated using ALOGPS
Material Safety Data Sheet (MSDS)
MOL File Show Link Image
SDF File Show Link Image
PDB File Show Link Image
2D Structure
3D Structure
Experimental PDB ID 1AT5 Link Image
Experimental PDB File Show
Experimental PDB Structure
Experimental 1H NMR Spectrum Not Available
Experimental 13C NMR Spectrum Not Available
Experimental 13C HSQC Spectrum Not Available
Predicted 1H NMR Spectrum Show Image
Show Peaklist
Predicted 13C NMR Spectrum Show Image
Show Peaklist
Mass Spectrum
Low Energy
Download File
Show Experimental Conditions Link Image
Medium Energy
Download File
Show Experimental Conditions Link Image
High Energy
Download File
Show Experimental Conditions Link Image
Simplified TOCSY Spectrum Not Available
BMRB Spectrum Not Available
Cellular Location
  • Cytoplasm (Predicted from LogP)
  • Extracellular
  • golgi apparatus
  • mitochondria
Biofluid Location
  • Cow_Milk
  • Rumen
Tissue Location
Concentrations (Normal)
Biofluid Rumen
Value 60087.08 +/- 5781.35 uM
Age 4-5 years old
Sex Female (lactating)
Condition Normal (0% barley grain in dry matter (DM) basis)
Breed Holstein-Friesian
Experimental Condition Rumen fluid for the analysis was collected 15-20 minutes before the morning feeding on days 12 and 21 of each experimental period. Cows were fed once daily at 0800.
Comments Not Available
References
  • The rumen metabolome (in preparation)
Biofluid Rumen
Value 45000.7 +/- 2.7 uM
Age N/A
Sex Female
Condition Normal
Breed Not Available
Experimental Condition Not Available
Comments Not Available
References
  • Metabolomics reveals unhealthy alterations in rumen metabolism with increased proportion of cereal grain in the diet of dairy cows. Burim N. Ametaj, Qendrim Zebeli, Fozia Saleem, Nikolaos Psychogios, Michael J. Lewis, Suzanna M. Dunn, Jianguo Xia and David S. Wishart Metabolomics 2010;6(4):583-594
Concentrations (Abnormal)
Biofluid Rumen
Value 56350+/- 7280 uM
Age 4-5 years old
Sex Female (lactating)
Condition 15% barley grain in dry matter (DM) basis
Breed Holstein-Friesian
Experimental Condition Rumen fluid for the analysis was collected 15-20 minutes before the morning feeding on days 12 and 21 of each experimental period. Cows were fed once daily at 0800.
Comments Not Available
References
  • The rumen metabolome (in preparation)
Biofluid Rumen
Value 54620 +/- 7940 uM
Age 4-5 years old
Sex Female (lactating)
Condition 30% barley grain in dry matter (DM) basis
Breed Holstein-Friesian
Experimental Condition Rumen fluid for the analysis was collected 15-20 minutes before the morning feeding on days 12 and 21 of each experimental period. Cows were fed once daily at 0800.
Comments Not Available
References
  • The rumen metabolome (in preparation)
Biofluid Rumen
Value 64280 +/- 6040 uM
Age 4-5 years old
Sex Female (lactating)
Condition 45% barley grain in dry matter (DM) basis
Breed Holstein-Friesian
Experimental Condition Rumen fluid for the analysis was collected 15-20 minutes before the morning feeding on days 12 and 21 of each experimental period. Cows were fed once daily at 0800.
Comments Not Available
References
  • The rumen metabolome (in preparation)
Pathway Names Not Available
HMDB Pathways Not Available
KEGG Pathways Not Available
SimCell Pathways Not Available
General References
  1. Wikipedia Link Image
Metabolic Enzymes
  1. Acyl-CoA synthetase short-chain family member 3, mitochondrial
  2. Acetylcholinesterase
  3. Putative N-acetylglucosamine-6-phosphate deacetylase
  4. Platelet-activating factor acetylhydrolase 2, cytoplasmic
  5. Platelet-activating factor acetylhydrolase
  6. Platelet-activating factor acetylhydrolase IB subunit gamma
  7. Serum paraoxonase/arylesterase 2
  8. Platelet-activating factor acetylhydrolase IB subunit beta
  9. N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
Enzyme 1 [top]
Enzyme 1 ID 367
Enzyme 1 Name Acyl-CoA synthetase short-chain family member 3, mitochondrial
Enzyme 1 Synonyms Not Available
Enzyme 1 Gene Name ACSS3
Enzyme 1 Protein Sequence >Acyl-CoA synthetase short-chain family member 3, mitochondrial
MKPSWLQCRKVTGAGGLGGSLPASSPARGAGPARRAYVAPGPRGALGGRGCRALSSGGGE
YKTHFAASVTDPERFWGKAAEQISWYKPWTKTLENRHSPSTSWFVEGMLNICYNAIDRHI
ENGKGDKIAIIYDSPVTNTKATITYKEVLEQVSKLAGVLVKHGVKKGDTVVIYMPMIPQA
MYAMLACARIGAIHSLIFGGFASKELSTRIDHAKPKLVITASFGIEPGRKVEYVPLVEEA
LRIGQHKPDKVLIYNRPHTDMVPLAPGYYLDWDEELSKAQSHDCVPVLSEHPLYILYTSG
TTGLPKGVVRPTGGYAVMLNWSMSSIYGLKPGEVWWAASDLGWVVGHSYICYGPLLHGNT
TVLYEGKPVGTPDAGAYFRVLAEHGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTL
FVAGERCDVETLEWSKKVFRVPVLDHWWQTETGSPITASCIGLGNSKTPPPGQAGKSVPG
YNVMILDDNMQKLKARCLGNIVVKLPLPPGAFSGLWKNQEAFKHLYFEKFPGYYDTMDAG
YMDEEGYVYVMSRVDDVINVAGHRISAGALEESILSLGIVADCAVVGKEDSLKGHIPLAL
CVLKKDINTTEEHVLEEIVKHVRQTIGPVAAFRKAVFVKQLPKTRSGKIPRSTLSALVNG
KPYKVSPTIEDPGIFEHIEAMLKQAS
Enzyme 1 Number of Residues 686
Enzyme 1 Molecular Weight 74804.8
Enzyme 1 Theoretical pI 9.09
Enzyme 1 GO Classification
Function
Process
Component
Enzyme 1 General Function Lipid transport and metabolism
Enzyme 1 Specific Function Activates acetate so that it can be used for lipid synthesis or for energy generation
Enzyme 1 Pathways Not Available
Enzyme 1 Reactions Not Available
Enzyme 1 Pfam Domain Function
Enzyme 1 Signals
  • None
Enzyme 1 Transmembrane Regions
  • None
Enzyme 1 Essentiality Not Available
Enzyme 1 GenBank ID Protein 154425894 Link Image
Enzyme 1 UniProtKB/Swiss-Prot ID A7MB45 Link Image
Enzyme 1 UniProtKB/Swiss-Prot Entry Name ACSS3_BOVIN Link Image
Enzyme 1 PDB ID Not Available
Enzyme 1 Cellular Location Not Available
Enzyme 1 Gene Sequence >2061 bp
ATGAAGCCGTCTTGGCTGCAGTGTCGCAAAGTCACCGGCGCGGGGGGCCTCGGCGGGTCC
CTGCCCGCGTCCTCTCCCGCGCGCGGAGCCGGCCCGGCCCGCCGGGCGTACGTGGCCCCC
GGCCCGCGGGGCGCTCTCGGGGGCCGGGGCTGCAGGGCGCTGTCCTCGGGCGGCGGCGAG
TACAAGACCCACTTCGCGGCCTCGGTGACCGACCCCGAGAGGTTCTGGGGCAAAGCCGCG
GAGCAGATCAGCTGGTACAAGCCCTGGACCAAGACGCTGGAGAACAGACATTCGCCTTCC
ACCAGTTGGTTTGTGGAAGGGATGCTGAACATTTGTTACAATGCCATCGATCGTCATATT
GAAAATGGTAAAGGAGATAAGATTGCTATCATTTATGACAGTCCTGTTACAAACACTAAA
GCCACTATTACCTATAAAGAAGTCCTGGAACAGGTCTCTAAGCTGGCTGGTGTTTTGGTC
AAGCATGGTGTCAAGAAGGGTGACACCGTGGTTATCTACATGCCCATGATCCCACAGGCG
ATGTACGCCATGCTGGCGTGTGCCAGGATAGGAGCCATCCACAGTCTCATATTTGGGGGA
TTTGCATCCAAAGAACTAAGCACTCGCATTGATCATGCAAAGCCCAAGCTGGTTATTACA
GCATCATTTGGCATTGAACCTGGAAGGAAGGTAGAGTACGTACCACTCGTAGAAGAGGCA
CTGAGAATAGGACAACACAAGCCAGATAAAGTTCTCATCTATAATCGTCCACATACGGAT
ATGGTTCCCTTGGCTCCAGGTTATTATCTTGATTGGGATGAAGAGCTCTCAAAAGCACAG
TCACATGATTGTGTTCCCGTTCTTTCTGAACATCCGCTGTATATCCTTTACACATCTGGA
ACGACGGGGTTGCCAAAGGGTGTGGTGAGGCCCACTGGAGGATACGCTGTAATGCTTAAC
TGGTCGATGTCTTCCATATATGGACTTAAACCTGGAGAGGTGTGGTGGGCAGCTTCTGAC
TTAGGCTGGGTTGTCGGACATTCCTATATCTGTTACGGACCTCTTCTACATGGAAATACT
ACAGTTTTATATGAGGGGAAGCCTGTGGGGACACCAGATGCTGGTGCCTATTTCCGTGTG
CTCGCGGAGCATGGAGTGGCTGCCTTGTTTACAGCGCCGACTGCAATTAGAGCGATCCGT
CAACAGGACCCTGGGGCAGCCTTGGGGAAGCAGTACTCGCTGACAAGGTTCAAAACACTG
TTTGTGGCTGGAGAACGATGTGATGTGGAGACGCTGGAATGGTCCAAAAAGGTCTTCAGA
GTGCCTGTGCTAGACCACTGGTGGCAAACTGAGACTGGATCCCCAATTACAGCATCTTGC
ATTGGATTAGGTAATTCTAAAACACCTCCTCCAGGGCAAGCAGGAAAAAGTGTTCCAGGA
TACAATGTTATGATTTTGGATGACAACATGCAAAAACTGAAGGCTCGGTGTTTAGGAAAC
ATCGTGGTAAAGTTGCCATTACCACCTGGAGCTTTTTCAGGACTCTGGAAGAATCAAGAG
GCATTCAAGCATTTATACTTTGAAAAATTTCCTGGATACTATGACACCATGGATGCTGGG
TACATGGATGAAGAAGGCTATGTTTATGTTATGTCTCGAGTTGATGACGTGATAAATGTT
GCAGGTCACAGGATTTCTGCAGGTGCCCTTGAGGAGTCTATCCTTTCCCTTGGCATTGTG
GCTGACTGTGCTGTTGTTGGGAAGGAAGATTCTTTGAAAGGTCATATCCCATTAGCCCTC
TGCGTGTTGAAAAAAGATATAAATACAACAGAGGAACACGTTTTAGAAGAAATTGTGAAA
CACGTTAGACAGACCATTGGCCCTGTGGCTGCTTTTCGGAAAGCGGTGTTTGTCAAACAG
TTACCCAAAACCAGATCTGGCAAAATTCCCCGCTCAACGCTGTCTGCCCTTGTCAATGGC
AAGCCATATAAGGTGTCTCCTACAATTGAAGATCCTGGAATTTTTGAGCACATAGAAGCC
ATGTTGAAGCAGGCATCATGA
Enzyme 1 GenBank Gene ID BC151332 Link Image
Enzyme 1 GeneCard ID ACSS3 Link Image
Enzyme 1 GenAtlas ID Not Available
Enzyme 1 HGNC ID Not Available
Enzyme 1 Chromosome Location Chromosome:1
Enzyme 1 Locus 12q21.31
Enzyme 1 SNPs SNPJam Report Link Image
Enzyme 1 General References Not Available
Enzyme 1 Metabolite References Not Available
Enzyme 2 [top]
Enzyme 2 ID 529
Enzyme 2 Name Acetylcholinesterase
Enzyme 2 Synonyms
  1. AChE
Enzyme 2 Gene Name ACHE
Enzyme 2 Protein Sequence >Acetylcholinesterase
MRPPWCPLHTPSLTPPLLLLLFLIGGGAEAEGPEDPELLVMVRGGRLRGLRLMAPRGPVS
AFLGIPFAEPPVGPRRFLPPEPKRPWPGVLNATAFQSVCYQYVDTLYPGFEGTEMWNPNR
ELSEDCLYLNVWTPYPRPSSPTPVLVWIYGGGFYSGASSLDVYDGRFLTQAEGTVLVSMN
YRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVG
MHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELV
ACLRARPAQDLVDHEWRVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGV
VKDEGSYFLVYGAPGFSKDNESLISRAQFLAGVRVGVPQASDLAAEAVVLHYTDWLHPED
PARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLSWPLWMGVPHGYE
IEFIFGLPLEPSLNYTIEERTFAQRLMRYWANFARTGDPNDPRDPKAPQWPPYTAGAQQY
VSLNLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQ
FDHYSKQDRCSDL
Enzyme 2 Number of Residues 613
Enzyme 2 Molecular Weight 67663.4
Enzyme 2 Theoretical pI 6.07
Enzyme 2 GO Classification
Function
Process
Component
Enzyme 2 General Function Lipid transport and metabolism
Enzyme 2 Specific Function Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft
Enzyme 2 Pathways Not Available
Enzyme 2 Reactions Not Available
Enzyme 2 Pfam Domain Function
Enzyme 2 Signals
  • 1-30
Enzyme 2 Transmembrane Regions
  • None
Enzyme 2 Essentiality Not Available
Enzyme 2 GenBank ID Protein 115305091 Link Image
Enzyme 2 UniProtKB/Swiss-Prot ID P23795 Link Image
Enzyme 2 UniProtKB/Swiss-Prot Entry Name ACES_BOVIN Link Image
Enzyme 2 PDB ID 1F8U Link Image
Enzyme 2 PDB File Show
Enzyme 2 3D Structure
Enzyme 2 Cellular Location Not Available
Enzyme 2 Gene Sequence >1842 bp
ATGAGGCCCCCGTGGTGTCCCCTGCACACGCCCTCCCTGACTCCCCCGCTCCTTCTCCTC
CTCTTCCTTCTGGGAGGAGGGGCAGAGGCCGAGGGCCCAGAGGACCCAGAGCTGCTGGTG
ATGGTGCGTGGGGGCCGACTGCGGGGTCTCCGCCTAATGGCCCCCAGGGGCCCTGTCTCT
GCTTTTCTGGGCATCCCCTTCGCAGAGCCACCTGTGGGCCCCCGTCGCTTTCTGCCACCA
GAGCCCAAGCGGCCCTGGCCAGGGGTGCTGAATGCCACGGCCTTCCAAAGCGTCTGCTAC
CAGTATGTGGACACCTTGTACCCCGGCTTTGAGGGCACTGAGATGTGGAACCCCAACCGT
GAGCTGAGTGAGGACTGCCTCTACCTCAACGTGTGGACACCGTACCCCCGGCCTTCGTCC
CCCACCCCTGTCCTCGTCTGGATCTATGGGGGTGGCTTCTACAGCGGGGCCTCCTCCCTG
GATGTGTACGATGGCCGTTTCCTGACCCAGGCTGAGGGGACTGTGCTGGTGTCCATGAAC
TACCGGGTGGGCGCCTTTGGCTTCTTGGCTCTGCCGGGGAGCCGGGAGGCCCCAGGCAAT
GTGGGGCTACTGGATCAGAGGCTGGCACTGCAGTGGGTGCAGGAGAATGTGGCAGCCTTC
GGGGGGGACCCAACGTCAGTGACTCTGTTTGGGGAAAGTGCAGGTGCCGCTTCTGTGGGC
ATGCACCTGCTGTCCCCACCCAGCCGGGGCCTGTTCCACAGGGCCGTGCTGCAGAGCGGG
GCACCCAATGGGCCCTGGGCCACGGTGGGCGTAGGAGAGGCCCGCCGGAGGGCCACACTG
CTGGCCCGCCTTGTGGGTTGTCCCCCGGGTGGGGCTGGTGGCAATGACACAGAGCTGGTG
GCCTGCCTGCGGGCACGGCCAGCTCAGGACCTGGTGGACCATGAGTGGCGCGTGCTGCCT
CAGGAAAGCGTCTTCCGCTTCTCCTTCGTGCCTGTGGTGGACGGAGACTTCCTCAGTGAC
ACACCCGAGGCCCTCATCAATGCTGGAGACTTCCATGGCCTGCAGGTGCTGGTGGGTGTG
GTGAAGGATGAGGGCTCCTATTTTCTGGTTTATGGGGCCCCAGGCTTCAGCAAAGACAAC
GAGTCTCTCATCAGCCGGGCCCAGTTCCTGGCCGGGGTGCGGGTCGGGGTCCCCCAGGCA
AGTGACCTGGCTGCCGAGGCTGTGGTCCTGCATTACACAGACTGGCTGCACCCTGAGGAC
CCAGCACGCCTGAGGGAGGCCTTGAGTGATGTGGTGGGTGACCACAACGTCGTGTGCCCC
GTGGCCCAGCTGGCTGGGCGACTGGCCGCTCAGGGCGCTCGTGTCTATGCCTACATCTTT
GAACACCGTGCATCCACGCTCTCCTGGCCCCTCTGGATGGGGGTGCCCCACGGCTACGAG
ATCGAGTTCATCTTCGGGCTCCCCCTGGAACCCTCGCTCAACTACACCATCGAGGAGAGA
ACCTTTGCCCAGCGACTGATGAGATACTGGGCCAACTTCGCCCGCACAGGAGACCCCAAT
GACCCCCGGGACCCCAAAGCCCCACAGTGGCCACCGTATACGGCGGGAGCGCAGCAGTAC
GTGAGCCTGAATCTGCGGCCTCTAGAGGTGCGGCGAGGGCTGCGAGCCCAGGCCTGCGCT
TTCTGGAATCGCTTCCTGCCCAAACTACTCAGCGCCACCGACACGCTGGACGAGGCGGAG
CGCCAGTGGAAGGCCGAGTTCCATCGCTGGAGCTCCTACATGGTGCACTGGAAGAACCAG
TTTGACCATTACAGCAAGCAGGATCGCTGCTCAGACCTGTGA
Enzyme 2 GenBank Gene ID BC123898 Link Image
Enzyme 2 GeneCard ID ACHE Link Image
Enzyme 2 GenAtlas ID Not Available
Enzyme 2 HGNC ID Not Available
Enzyme 2 Chromosome Location Chromosome:7
Enzyme 2 Locus 7q22
Enzyme 2 SNPs SNPJam Report Link Image
Enzyme 2 General References
  1. [PubMed Link Image]
Enzyme 2 Metabolite References Not Available
Enzyme 3 [top]
Enzyme 3 ID 938
Enzyme 3 Name Putative N-acetylglucosamine-6-phosphate deacetylase
Enzyme 3 Synonyms
  1. GlcNAc 6-P deacetylase
  2. Amidohydrolase domain-containing protein 2
Enzyme 3 Gene Name AMDHD2
Enzyme 3 Protein Sequence >Putative N-acetylglucosamine-6-phosphate deacetylase
MRGGQGAARAPVIQFTNCRILRGGALLREDLWVRGGRILDPEKLFFEERRVADEQRDCGG
CILAPGFIDVQINGGFGVDFSQASEDVGSGVALVARRILSHGVTSFCPTLVTSPLEVYHK
VLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAHLRSFEADAFQDVLATYGGLDN
VRIVTLAPELGHSQEVIRALTALGICVSLGHSVADLGTAEEAVQSGATFITHLFNAMLPF
HHRDPGIVGLLTSDRLPAGRHIFYGMIADGIHTNPAALRIAHRAHPKGLVLVTDAVPALG
LGNGRHTLGQQEVEVDGLTAYVAGTNTLSGSIAPMDTCVRHFLQATGCSVESALEAASLH
PAQLLGLEKRKGTLDFGADADFVVLDDSLHVRATYISGELVWQVEEARP
Enzyme 3 Number of Residues 409
Enzyme 3 Molecular Weight 43495.2
Enzyme 3 Theoretical pI 6.37
Enzyme 3 GO Classification
Function
Process
Component
Enzyme 3 General Function Carbohydrate transport and metabolism
Enzyme 3 Specific Function N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate + acetate
Enzyme 3 Pathways Not Available
Enzyme 3 Reactions Not Available
Enzyme 3 Pfam Domain Function
Enzyme 3 Signals
  • None
Enzyme 3 Transmembrane Regions
  • None
Enzyme 3 Essentiality Not Available
Enzyme 3 GenBank ID Protein 154425852 Link Image
Enzyme 3 UniProtKB/Swiss-Prot ID A7MBC0 Link Image
Enzyme 3 UniProtKB/Swiss-Prot Entry Name NAGA_BOVIN Link Image
Enzyme 3 PDB ID Not Available
Enzyme 3 Cellular Location Not Available
Enzyme 3 Gene Sequence >1230 bp
ATGCGCGGCGGGCAGGGCGCGGCGCGGGCCCCGGTGATCCAGTTCACCAACTGCCGCATC
TTGAGGGGTGGCGCGCTGCTCAGGGAGGACCTCTGGGTGCGCGGGGGCCGCATCCTGGAC
CCGGAGAAGCTGTTCTTTGAGGAGCGGCGCGTGGCTGACGAGCAGCGGGACTGCGGCGGC
TGCATCTTGGCGCCCGGCTTCATCGACGTGCAGATCAACGGTGGATTTGGCGTTGACTTC
TCACAAGCCTCGGAGGACGTGGGTTCGGGGGTTGCCCTAGTGGCCCGGAGGATCCTGTCG
CATGGAGTCACCTCTTTCTGCCCCACGTTGGTCACATCGCCACTGGAGGTTTATCACAAG
GTCCTTCCTCAGATCCCTGTGAAGAGTGGTGGTCCCCATGGGGCAGGGGTCCTCGGGGTG
CACCTGGAGGGCCCATTCATCAGCCGGGAGAAGCGGGGCGCGCACCCCGAGGCCCACCTG
CGCTCCTTTGAAGCTGACGCTTTCCAAGACGTGCTGGCCACCTACGGGGGCCTGGACAAT
GTCCGCATCGTGACGCTGGCCCCCGAGCTGGGCCACAGCCAGGAGGTGATCCGGGCGCTG
ACGGCCCTCGGCATCTGCGTGTCCTTAGGGCACTCGGTGGCTGACCTGGGGACTGCGGAG
GAAGCCGTGCAGAGTGGGGCCACCTTCATCACCCACCTCTTCAACGCCATGCTGCCTTTC
CACCACCGCGACCCAGGCATCGTGGGGCTCCTGACCAGCGATCGGCTGCCTGCAGGCCGT
CATATTTTCTACGGGATGATTGCTGACGGTATACACACCAACCCGGCCGCCCTGCGCATC
GCCCACCGGGCCCATCCCAAGGGGCTGGTGCTAGTCACTGATGCTGTCCCTGCACTGGGC
TTGGGCAACGGCCGACACACGCTGGGGCAGCAGGAGGTGGAGGTGGATGGGCTGACAGCT
TATGTGGCAGGCACCAACACACTGAGCGGCAGCATCGCCCCGATGGACACCTGCGTGCGG
CACTTCCTGCAGGCCACAGGCTGCAGTGTGGAGTCCGCTCTGGAGGCTGCGTCCCTGCAT
CCAGCACAGCTGCTGGGGCTGGAGAAGCGCAAGGGGACCCTGGACTTCGGGGCTGACGCA
GACTTCGTGGTGCTCGACGACTCTCTTCACGTCCGGGCCACCTACATCTCGGGCGAGCTG
GTGTGGCAGGTGGAGGAGGCCAGGCCGTGA
Enzyme 3 GenBank Gene ID BC151478 Link Image
Enzyme 3 GeneCard ID AMDHD2 Link Image
Enzyme 3 GenAtlas ID Not Available
Enzyme 3 HGNC ID Not Available
Enzyme 3 Chromosome Location Chromosome:1
Enzyme 3 Locus 16p13.3
Enzyme 3 SNPs SNPJam Report Link Image
Enzyme 3 General References Not Available
Enzyme 3 Metabolite References Not Available
Enzyme 4 [top]
Enzyme 4 ID 943
Enzyme 4 Name Platelet-activating factor acetylhydrolase 2, cytoplasmic
Enzyme 4 Synonyms
  1. Serine-dependent phospholipase A2
Enzyme 4 Gene Name PAFAH2
Enzyme 4 Protein Sequence >Platelet-activating factor acetylhydrolase 2, cytoplasmic
MGVNQSVSFPPVTGPHLVGCGDVMEGQSLQGSFFRLFYPCQEAEETSEQPLWIPRYEYCA
GLAEYLKFNKRWGGLLFNLGVGSCRLPVSWNGPFKTKDSGYPLIIFSHGMGAFRTVYSAF
CMELASRGFVVAVPEHRDGSAAATCFCKQTPEENQPDNEALKEEWIPHRQIEEGEKEFYV
RNYQVHQRVSECVRVLKILQEVTAGQAVLNILPGGLDLMTLKGGIDVSRVAVMGHSFGGA
TAILALAKEMQFRCAVALDAWMFPLEHDFYPTARGPIFFINAEKFQTVETVNLMKKICDQ
HHQSRIITVLGSVHRSLTDFVFVAGNWISKFFSSHTRGSLDPYEGQETVVRAMLAFLQKH
LDLKEDYDQWNNFIEGIGPSLTPGAPHHLSSL
Enzyme 4 Number of Residues 392
Enzyme 4 Molecular Weight 43864.9
Enzyme 4 Theoretical pI 6.39
Enzyme 4 GO Classification
Function
Process
Component
Enzyme 4 General Function Involved in 1-alkyl-2-acetylglycerophosphocholine ester
Enzyme 4 Specific Function Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme
Enzyme 4 Pathways Not Available
Enzyme 4 Reactions Not Available
Enzyme 4 Pfam Domain Function
Enzyme 4 Signals
  • None
Enzyme 4 Transmembrane Regions
  • None
Enzyme 4 Essentiality Not Available
Enzyme 4 GenBank ID Protein 1765862 Link Image
Enzyme 4 UniProtKB/Swiss-Prot ID P79106 Link Image
Enzyme 4 UniProtKB/Swiss-Prot Entry Name PAFA2_BOVIN Link Image
Enzyme 4 PDB ID Not Available
Enzyme 4 Cellular Location Not Available
Enzyme 4 Gene Sequence >1179 bp
ATGGGGGTCAACCAGTCTGTGAGCTTCCCACCCGTCACGGGACCCCACCTCGTAGGCTGT
GGGGATGTGATGGAGGGTCAGAGCCTCCAGGGCAGCTTCTTTCGACTGTTCTACCCGTGC
CAAGAGGCAGAGGAGACCTCGGAGCAGCCCCTGTGGATTCCCCGCTATGAGTACTGCGCT
GGCCTGGCCGAATACCTAAAGTTTAATAAGCGCTGGGGGGGGTTACTGTTCAACCTGGGT
GTGGGATCTTGTCGCCTGCCTGTTAGCTGGAATGGCCCCTTTAAAACAAAGGACTCTGGA
TACCCCTTGATCATCTTCTCTCATGGCATGGGAGCCTTCAGGACAGTGTATTCAGCCTTC
TGCATGGAGCTGGCTTCTCGTGGCTTTGTGGTTGCTGTACCAGAGCACAGGGATGGGTCA
GCTGCGGCCACCTGTTTCTGCAAGCAGACCCCAGAGGAGAACCAGCCTGACAATGAGGCC
CTGAAGGAGGAATGGATCCCCCACCGTCAAATTGAGGAAGGGGAGAAGGAATTCTATGTT
CGGAACTACCAGGTGCATCAGAGGGTGAGCGAGTGTGTGAGGGTGTTGAAGATCCTACAA
GAGGTCACTGCTGGGCAGGCCGTTCTCAACATCTTGCCTGGCGGATTGGATCTGATGACC
TTGAAGGGCGGCATTGACGTGAGCCGTGTGGCTGTAATGGGACATTCATTTGGAGGGGCC
ACAGCTATTCTGGCCTTGGCCAAGGAGATGCAATTTAGGTGTGCTGTGGCTTTGGACGCT
TGGATGTTTCCTCTGGAGCATGACTTTTACCCCACGGCCCGAGGCCCTATCTTCTTTATC
AATGCTGAGAAGTTCCAGACAGTGGAGACTGTCAACTTGATGAAAAAGATTTGTGACCAG
CACCACCAATCCAGGATCATAACTGTCCTTGGTTCTGTTCATCGGAGTCTAACCGACTTT
GTTTTTGTGGCTGGTAACTGGATTAGTAAATTCTTCTCCAGTCACACCCGTGGAAGCTTG
GACCCCTATGAAGGTCAGGAGACCGTGGTGCGGGCCATGTTGGCCTTCCTGCAGAAGCAT
CTTGACCTGAAAGAGGACTATGACCAGTGGAACAACTTCATTGAAGGCATTGGCCCATCA
CTGACCCCAGGGGCCCCACACCATCTGTCCAGCCTGTAG
Enzyme 4 GenBank Gene ID D87559 Link Image
Enzyme 4 GeneCard ID PAFAH2 Link Image
Enzyme 4 GenAtlas ID Not Available
Enzyme 4 HGNC ID Not Available
Enzyme 4 Chromosome Location Chromosome:1
Enzyme 4 Locus 1p36
Enzyme 4 SNPs SNPJam Report Link Image
Enzyme 4 General References
  1. [PubMed Link Image]
Enzyme 4 Metabolite References Not Available
Enzyme 5 [top]
Enzyme 5 ID 944
Enzyme 5 Name Platelet-activating factor acetylhydrolase
Enzyme 5 Synonyms
  1. PAF acetylhydrolase
  2. PAF 2-acylhydrolase
  3. LDL-associated phospholipase A2
  4. LDL-PLA(2)
  5. 2-acetyl-1-alkylglycerophosphocholine esterase
  6. 1-alkyl-2-acetylglycerophosphocholine esterase
Enzyme 5 Gene Name PLA2G7
Enzyme 5 Protein Sequence >Platelet-activating factor acetylhydrolase
MLPSKLHALFCLCTCLALVYPFDWQDLNPVAYIESPAWVSKIQALMAAANIGQSKIPRGN
GSYSVGCTDLMFDYTNKGTFLRLYYPSQDDDHSDTLWIPNKEYFLGLSKFLGTHWLVGKI
MGLFFGSMTTPAAWNAHLRTGEKYPLIIFSHGLGAFRTIYSAIGIDLASHGFIVAAVEHR
DGSASSTYYFKDQSAVEIGNKSWLYLRTLKRGEEEFPLRNEQLRQRAKECSQALSLILDI
DHGRPVTNVLDLEFDVEQLKDSIDRDKIAIIGHSFGGATVIQTLSEDQRFRCGIALDAWM
FPVGDEVYSRIPQPLFFINSERFQYPSNIIRMKKCFLPDRERKMITIRGSVHQNFVDFTF
ATSKIIGYLFTLKGDIDSNVAISLSNKASLAFLQKHLGLQKDFDQWDSLVEGEDHNLIPG
TNINTTNHQAILQNSTGIERPNLD
Enzyme 5 Number of Residues 444
Enzyme 5 Molecular Weight 50132.7
Enzyme 5 Theoretical pI 6.57
Enzyme 5 GO Classification
Function
Process
Component
Enzyme 5 General Function Involved in 1-alkyl-2-acetylglycerophosphocholine ester
Enzyme 5 Specific Function Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids
Enzyme 5 Pathways Not Available
Enzyme 5 Reactions Not Available
Enzyme 5 Pfam Domain Function
Enzyme 5 Signals
  • 1-21
Enzyme 5 Transmembrane Regions
  • None
Enzyme 5 Essentiality Not Available
Enzyme 5 GenBank ID Protein 1054899 Link Image
Enzyme 5 UniProtKB/Swiss-Prot ID Q28017 Link Image
Enzyme 5 UniProtKB/Swiss-Prot Entry Name PAFA_BOVIN Link Image
Enzyme 5 PDB ID Not Available
Enzyme 5 Cellular Location Not Available
Enzyme 5 Gene Sequence >1335 bp
ATGTTACCGTCCAAATTGCATGCGCTTTTCTGCCTCTGCACCTGCCTTGCACTGGTTTAT
CCTTTTGACTGGCAAGACCTGAATCCAGTTGCCTATATTGAATCACCAGCATGGGTCAGT
AAGATACAAGCTCTGATGGCTGCTGCAAACATTGGTCAATCTAAAATCCCCAGAGGAAAT
GGATCTTATTCCGTCGGTTGTACAGACTTGATGTTTGATTACACTAATAAGGGCACCTTC
TTGCGTTTGTATTATCCATCTCAAGATGATGATCACTCCGACACCCTTTGGATCCCAAAC
AAAGAATATTTTTTGGGTCTTAGTAAATTTCTTGGAACACACTGGCTTGTGGGCAAAATT
ATGGGCTTATTCTTCGGTTCAATGACAACTCCTGCAGCCTGGAATGCACATCTGAGGACT
GGGGAAAAATACCCACTAATTATTTTTTCTCATGGTCTTGGAGCATTCAGGACGATTTAT
TCTGCTATTGGCATTGATCTGGCATCCCACGGGTTTATAGTTGCTGCTGTAGAACACAGG
GATGGCTCTGCATCCTCGACATACTATTTCAAGGACCAGTCTGCTGTAGAAATAGGCAAC
AAGTCTTGGCTCTATCTCAGAACCCTGAAGCGAGGAGAGGAGGAGTTTCCTTTACGAAAT
GAGCAGTTACGGCAACGAGCAAAGGAATGTTCTCAAGCTCTCAGTTTGATTCTGGACATT
GATCACGGGAGGCCAGTGACGAATGTACTAGATTTAGAGTTTGATGTGGAACAGCTGAAG
GACTCTATTGATAGGGATAAAATAGCCATTATTGGACATTCTTTTGGTGGAGCCACAGTT
ATTCAGACTCTTAGTGAAGACCAGAGATTCAGGTGTGGCATTGCTCTGGATGCATGGATG
TTTCCCGTGGGTGATGAAGTATATTCCAGAATTCCTCAACCCCTCTTTTTTATCAACTCG
GAACGATTCCAATACCCTTCTAATATCATAAGAATGAAAAAATGCTTCTTACCTGATAGA
GAACGAAAAATGATTACAATCAGGGGTTCGGTCCATCAGAATTTTGTTGACTTCACTTTT
GCCACTAGCAAAATAATTGGCTACCTATTCACACTGAAAGGAGACATCGATTCCAATGTA
GCCATCAGCCTTAGCAACAAAGCTTCCTTAGCGTTCTTACAAAAACATTTAGGACTTCAG
AAAGATTTTGATCAGTGGGATTCTTTAGTTGAAGGCGAAGATCACAATCTTATTCCAGGG
ACCAACATTAACACAACCAACCACCAAGCCATTCTGCAGAACTCCACAGGAATAGAGAGA
CCAAATTTAGATTAA
Enzyme 5 GenBank Gene ID U34247 Link Image
Enzyme 5 GeneCard ID PLA2G7 Link Image
Enzyme 5 GenAtlas ID Not Available
Enzyme 5 HGNC ID Not Available
Enzyme 5 Chromosome Location Chromosome:6
Enzyme 5 Locus 6p21.2-p12
Enzyme 5 SNPs SNPJam Report Link Image
Enzyme 5 General References
  1. [PubMed Link Image]
Enzyme 5 Metabolite References Not Available
Enzyme 6 [top]
Enzyme 6 ID 945
Enzyme 6 Name Platelet-activating factor acetylhydrolase IB subunit gamma
Enzyme 6 Synonyms
  1. PAF acetylhydrolase 29 kDa subunit
  2. PAF-AH 29 kDa subunit
  3. PAF-AH subunit gamma
  4. PAFAH subunit gamma
Enzyme 6 Gene Name PAFAH1B3
Enzyme 6 Protein Sequence >Platelet-activating factor acetylhydrolase IB subunit gamma
MSGDENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
LFSPLHALNFGIGGDSTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRRVNELVRAALAGHPRAHFLDADPGFVH
SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLTQDQGQGGAPLPEPSP
Enzyme 6 Number of Residues 232
Enzyme 6 Molecular Weight 25865.2
Enzyme 6 Theoretical pI 6.97
Enzyme 6 GO Classification
Function
Process
Component
Enzyme 6 General Function Involved in 1-alkyl-2-acetylglycerophosphocholine ester
Enzyme 6 Specific Function Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain
Enzyme 6 Pathways Not Available
Enzyme 6 Reactions Not Available
Enzyme 6 Pfam Domain Function
Enzyme 6 Signals
  • None
Enzyme 6 Transmembrane Regions
  • None
Enzyme 6 Essentiality Not Available
Enzyme 6 GenBank ID Protein 556479 Link Image
Enzyme 6 UniProtKB/Swiss-Prot ID Q29460 Link Image
Enzyme 6 UniProtKB/Swiss-Prot Entry Name PA1B3_BOVIN Link Image
Enzyme 6 PDB ID 1FXW Link Image
Enzyme 6 PDB File Show
Enzyme 6 3D Structure
Enzyme 6 Cellular Location Not Available
Enzyme 6 Gene Sequence >699 bp
ATGAGTGGAGACGAGAACCCAGCCAGCAAGCCCACGCCAGTGCAGGACGTGCAGGGTGAC
GGGCGCTGGATGTCCCTGCACCATCGGTTCGTAGCCGACAGCAAAGATAAGGAACCCGAA
GTCGTCTTCATCGGTGACTCCTTGGTCCAGCTGATGCACCAGTGCGAGATCTGGCGGGAG
CTCTTTTCCCCTCTGCACGCACTTAACTTTGGCATTGGCGGTGACAGCACACAGCATGTG
CTGTGGCGTCTGGAGAATGGAGAGCTGGAACACATCCGGCCCAAGATTGTGGTGGTCTGG
GTTGGTACCAACAACCACGGGCACACTGCAGAGCAGGTGACTGGGGGCATCAAGGCCATA
GTGCAGCTGGTGAACGAGCGGCAGCCCCAGGCACGGGTCGTGGTGCTGGGCCTGCTTCCT
CGGGGCCAGCACCCCAACCCACTTCGAGAGAAAAACCGACGGGTGAATGAGCTGGTACGG
GCAGCACTGGCCGGCCACCCTCGGGCCCACTTCCTGGACGCAGACCCTGGCTTTGTGCAC
TCAGATGGTACCATCAGCCACCATGACATGTACGATTACCTGCACCTGAGCCGTCTGGGG
TACACACCTGTTTGCCGGGCCCTGCACTCCTTGCTTCTGCGTCTGCTAACCCAAGACCAG
GGACAGGGTGGTGCCCCCCTGCCGGAACCCAGCCCCTAA
Enzyme 6 GenBank Gene ID D30789 Link Image
Enzyme 6 GeneCard ID PAFAH1B3 Link Image
Enzyme 6 GenAtlas ID Not Available
Enzyme 6 HGNC ID Not Available
Enzyme 6 Chromosome Location Chromosome:1
Enzyme 6 Locus 19q13.1
Enzyme 6 SNPs SNPJam Report Link Image
Enzyme 6 General References
  1. [PubMed Link Image]
Enzyme 6 Metabolite References Not Available
Enzyme 7 [top]
Enzyme 7 ID 946
Enzyme 7 Name Serum paraoxonase/arylesterase 2
Enzyme 7 Synonyms
  1. PON 2
  2. Serum aryldialkylphosphatase 2
  3. A-esterase 2
  4. Aromatic esterase 2
Enzyme 7 Gene Name PON2
Enzyme 7 Protein Sequence >Serum paraoxonase/arylesterase 2
MGRLLALSLLGIALALLGERLLALRNRLKASREVESVDLPNCHLIKGIEAGAEDIDILPN
GLAFFSVGLKCPGLHSFAPDKPGGILMMDLNEENPRALELRVSRGFNLASFNPHGISTFI
DSDDTVYLFVVNHPEFKNTVEIFKFEEEENSLLHLKTIKHELLPSVNDIIAVGPEHFYAT
NDHYFSDPFLKYLETYLNLHWTNVVYYSPNEVKVVAEGFDSANGINISPDKKYIYVADIL
AHEIHVLEKHPNMNLTQLKVLKLDTLVDNLSIDPSSGDVLVGCHPNGQKLFVYDPKNPPS
SEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDKKLLIGTLYHRALYCEL
Enzyme 7 Number of Residues 354
Enzyme 7 Molecular Weight 39420.8
Enzyme 7 Theoretical pI 5.52
Enzyme 7 GO Classification
Function
Process
Component
Enzyme 7 General Function Involved in aryldialkylphosphatase activity
Enzyme 7 Specific Function Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters
Enzyme 7 Pathways Not Available
Enzyme 7 Reactions Not Available
Enzyme 7 Pfam Domain Function
Enzyme 7 Signals
  • 1-
Enzyme 7 Transmembrane Regions
  • None
Enzyme 7 Essentiality Not Available
Enzyme 7 GenBank ID Protein 61553203 Link Image
Enzyme 7 UniProtKB/Swiss-Prot ID Q58DS7 Link Image
Enzyme 7 UniProtKB/Swiss-Prot Entry Name PON2_BOVIN Link Image
Enzyme 7 PDB ID Not Available
Enzyme 7 Cellular Location Not Available
Enzyme 7 Gene Sequence >1065 bp
ATGGGGCGGCTGCTGGCGCTGAGCTTGCTGGGGATCGCGCTGGCGCTGCTGGGCGAGAGG
CTCCTGGCGCTCAGGAATCGACTTAAAGCCTCCAGAGAAGTGGAATCTGTAGACCTTCCT
AATTGCCACCTGATTAAAGGAATCGAAGCCGGCGCTGAAGATATTGACATACTTCCCAAC
GGTCTGGCTTTCTTTAGTGTGGGTCTAAAATGTCCAGGCCTCCACAGTTTTGCACCAGAT
AAGCCTGGAGGAATACTAATGATGGATCTAAATGAAGAAAACCCAAGGGCACTGGAATTA
AGAGTCAGCCGTGGATTTAATTTGGCTTCATTTAATCCACATGGTATCAGCACTTTCATA
GACAGTGATGACACCGTTTATCTCTTTGTTGTAAACCACCCAGAATTCAAGAATACAGTA
GAAATTTTTAAATTTGAAGAGGAAGAAAATTCTCTTTTGCATCTAAAAACAATCAAACAT
GAGCTTCTTCCAAGTGTGAATGATATCATAGCTGTTGGACCAGAACATTTCTATGCTACC
AATGACCACTATTTCTCTGATCCTTTCTTAAAGTATTTGGAAACATACTTGAACTTACAC
TGGACAAATGTTGTTTACTACAGTCCAAATGAAGTTAAAGTGGTAGCAGAAGGATTCGAT
TCAGCAAATGGGATCAATATTTCACCTGATAAAAAGTACATCTATGTTGCTGATATATTG
GCTCATGAAATTCATGTTTTGGAAAAGCACCCTAATATGAATTTAACTCAGTTGAAGGTA
CTCAAGTTGGATACCCTGGTGGATAATTTATCTATTGACCCTTCCTCGGGGGACGTCTTG
GTAGGCTGTCACCCCAACGGCCAGAAGCTCTTCGTGTATGACCCGAAGAATCCTCCCTCG
TCAGAGGTTCTCCGCATCCAGAATATTTTATCTGAGAAGCCTACAGTGACTACAGTTTAT
GCCAACAATGGATCTGTTCTCCAGGGAAGTTCTGTGGCCTCTGTGTATGACAAGAAGCTG
CTCATAGGCACTTTATACCACAGAGCCCTATACTGTGAGCTCTAA
Enzyme 7 GenBank Gene ID BT021520 Link Image
Enzyme 7 GeneCard ID PON2 Link Image
Enzyme 7 GenAtlas ID Not Available
Enzyme 7 HGNC ID Not Available
Enzyme 7 Chromosome Location Chromosome:7
Enzyme 7 Locus 7q21.3
Enzyme 7 SNPs SNPJam Report Link Image
Enzyme 7 General References
  1. [PubMed Link Image]
Enzyme 7 Metabolite References Not Available
Enzyme 8 [top]
Enzyme 8 ID 947
Enzyme 8 Name Platelet-activating factor acetylhydrolase IB subunit beta
Enzyme 8 Synonyms
  1. PAF acetylhydrolase 30 kDa subunit
  2. PAF-AH 30 kDa subunit
  3. PAF-AH subunit beta
  4. PAFAH subunit beta
Enzyme 8 Gene Name PAFAH1B2
Enzyme 8 Protein Sequence >Platelet-activating factor acetylhydrolase IB subunit beta
MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
Enzyme 8 Number of Residues 229
Enzyme 8 Molecular Weight 25569.1
Enzyme 8 Theoretical pI 5.80
Enzyme 8 GO Classification
Function
Process
Component
Enzyme 8 General Function Amino acid transport and metabolism
Enzyme 8 Specific Function Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit
Enzyme 8 Pathways Not Available
Enzyme 8 Reactions Not Available
Enzyme 8 Pfam Domain Function
Enzyme 8 Signals
  • None
Enzyme 8 Transmembrane Regions
  • None
Enzyme 8 Essentiality Not Available
Enzyme 8 GenBank ID Protein 728490 Link Image
Enzyme 8 UniProtKB/Swiss-Prot ID P68401 Link Image
Enzyme 8 UniProtKB/Swiss-Prot Entry Name PA1B2_BOVIN Link Image
Enzyme 8 PDB ID 1FXW Link Image
Enzyme 8 PDB File Show
Enzyme 8 3D Structure
Enzyme 8 Cellular Location Not Available
Enzyme 8 Gene Sequence >690 bp
ATGAGCCAAGGAGACTCAAACCCAGCAGCCATTCCACATGCAGCAGAAGATATTCAAGGA
GACGACAGATGGATGTCTCAGCACAACAGATTTGTCCTGGACTGCAAAGACAAAGAGCCG
GATGTCCTGTTCGTGGGGGACTCCATGGTACAGTTGATGCAGCAGTATGAGATATGGCGA
GAGCTTTTTTCTCCACTTCATGCACTGAATTTTGGAATTGGGGGAGATACAACAAGACAT
GTTTTATGGAGACTAAAGAATGGAGAACTGGAGAATATTAAACCTAAGGTCATCGTTGTC
TGGGTAGGAACAAACAACCATGAAAATACAGCAGAGGAAGTAGCAGGTGGAATCGAGGCC
ATCGTACAGCTTATCAACACAAGGCAGCCACAGGCCAAAATCATTGTATTGGGTTTGTTA
CCTCGAGGTGAGAAGCCCAACCCCTTGAGGCAAAAGAATGCCAAGGTGAACCAGCTCCTC
AAGGTCTCCCTGCCGAAGCTCGCCAACGTTCAGCTCCTGGACACAGACGGGGGCTTCGTG
CACTCGGACGGTGCCATCTCCTGCCACGACATGTTTGATTTTCTGCATCTCACAGGAGGT
GGCTATGCAAAGATCTGCAAACCCCTCCATGAACTGATCATGCAGTTGTTGGAGGAAACA
CCTGAGGAAAAACAAACCACCATTGCCTGA
Enzyme 8 GenBank Gene ID D49678 Link Image
Enzyme 8 GeneCard ID PAFAH1B2 Link Image
Enzyme 8 GenAtlas ID Not Available
Enzyme 8 HGNC ID Not Available
Enzyme 8 Chromosome Location Chromosome:1
Enzyme 8 Locus 11q23
Enzyme 8 SNPs SNPJam Report Link Image
Enzyme 8 General References
  1. [PubMed Link Image]
Enzyme 8 Metabolite References Not Available
Enzyme 9 [top]
Enzyme 9 ID 948
Enzyme 9 Name N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
Enzyme 9 Synonyms
  1. Phosphatidylinositol-glycan biosynthesis class L protein
  2. PIG-L
Enzyme 9 Gene Name PIGL
Enzyme 9 Protein Sequence >N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
MEVAAPLLCLAAAVLVWGVLWVWGSWERMTRPEQAGLPGGGSRTLLVTAHPDDEAMFFAP
TILGLARLRHQLFLLCFSAGNYYNQGEIRKKELLQSCDVLGIPPSNVMIIENRDFPDDPD
VRWDPDRAADVLLQHVEANGIKLVVTFDEGGVSGHSNHVALNAAVRTLQAEGKLPKGCSV
LTLQSVNLLRKYLCLLDLPCSLLLARDALFVLTQREAAQAQRAMSCHRSQLLWFRRLYML
FSRYMRINSLNFL
Enzyme 9 Number of Residues 253
Enzyme 9 Molecular Weight 28329.7
Enzyme 9 Theoretical pI 7.79
Enzyme 9 GO Classification
Function
Process
Component
Enzyme 9 General Function Involved in N-acetylglucosaminylphosphatidylinositol de
Enzyme 9 Specific Function Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol
Enzyme 9 Pathways
  • Glycolipid biosynthesis
  • glycosylphosphatidylinositol- anchor biosynthesis
Enzyme 9 Reactions Not Available
Enzyme 9 Pfam Domain Function
Enzyme 9 Signals
  • None
Enzyme 9 Transmembrane Regions
  • 3-23
Enzyme 9 Essentiality Not Available
Enzyme 9 GenBank ID Protein 151557003 Link Image
Enzyme 9 UniProtKB/Swiss-Prot ID A6QQ24 Link Image
Enzyme 9 UniProtKB/Swiss-Prot Entry Name PIGL_BOVIN Link Image
Enzyme 9 PDB ID Not Available
Enzyme 9 Cellular Location Not Available
Enzyme 9 Gene Sequence >762 bp
ATGGAAGTGGCGGCGCCGCTTCTGTGTTTGGCGGCGGCTGTCCTGGTATGGGGCGTTCTC
TGGGTTTGGGGCTCCTGGGAGCGAATGACGAGGCCGGAGCAGGCTGGCCTGCCCGGAGGC
GGAAGCCGGACACTTCTGGTGACGGCGCACCCCGACGATGAAGCCATGTTCTTTGCTCCC
ACTATTCTAGGCTTGGCCCGCCTGCGGCACCAGTTGTTCCTGCTCTGCTTCTCCGCAGGA
AATTACTACAATCAAGGGGAGATCCGTAAGAAGGAACTCTTGCAGAGCTGTGATGTTCTG
GGGATTCCCCCCTCCAACGTAATGATTATTGAAAACAGGGATTTCCCAGATGACCCAGAC
GTGCGCTGGGACCCAGACCGGGCAGCTGATGTCCTCCTCCAGCACGTAGAGGCCAATGGC
ATCAAGCTGGTGGTGACCTTCGATGAGGGGGGCGTGAGTGGGCACAGCAACCACGTGGCT
CTGAATGCAGCTGTGAGGACCCTGCAGGCAGAAGGGAAGCTACCCAAAGGGTGCTCGGTG
CTCACGCTCCAGTCTGTGAACCTGCTGCGCAAATACCTCTGTCTGCTGGACCTACCCTGC
TCCCTGCTGCTCGCCCGCGACGCCCTCTTCGTGCTCACCCAACGTGAGGCAGCCCAGGCC
CAGAGAGCCATGTCCTGCCACCGCAGCCAGCTGCTCTGGTTCCGCCGCCTCTATATGCTG
TTCTCCCGCTACATGAGGATTAACTCTCTGAACTTTCTCTGA
Enzyme 9 GenBank Gene ID BC149604 Link Image
Enzyme 9 GeneCard ID PIGL Link Image
Enzyme 9 GenAtlas ID Not Available
Enzyme 9 HGNC ID Not Available
Enzyme 9 Chromosome Location Chromosome:1
Enzyme 9 Locus 17p12-p11.2
Enzyme 9 SNPs SNPJam Report Link Image
Enzyme 9 General References Not Available
Enzyme 9 Metabolite References Not Available