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Bovine Rumen Metabolome Database



Showing metabocard for Calcium (RMDB00464)

Legend: metabolite field enzyme field

Version 1.0
Creation Date 2006-08-15 18:25:35
Update Date 2009-10-28 12:03:08
Accession Number RMDB00464
Common Name Calcium
Description Calcium is essential for the normal growth and maintenance of bones and teeth, and calcium requirements must be met throughout life. Requirements are greatest during periods of growth, such as childhood, during pregnancy and when breast-feeding. Long-term calcium deficiency can lead to osteoporosis, in which the bone deteriorates and there is an increased risk of fractures. Adults need between 1,000 and 1,300 mg of calcium in their daily diet. Calcium is essential for living organisms, particularly in cell physiology, and is the most common metal in many animals. Physiologically, it exists as an ion in the body. Calcium combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Calcium is an important component of a healthy diet. A deficit can affect bone and tooth formation, while overretention can cause kidney stones. Vitamin D is needed to absorb calcium. Dairy products, such as milk and cheese, are a well-known source of calcium. However, some individuals are allergic to dairy products and even more people, particularly those of non-European descent, are lactose-intolerant, leaving them unable to consume dairy products. Fortunately, many other good sources of calcium exist. These include: seaweeds such as kelp, wakame and hijiki; nuts and seeds (like almonds and sesame); beans; amaranth; collard greens; okra; rutabaga; broccoli; kale; and fortified products such as orange juice and soy milk. Calcium has also been found to assist in the production of lymphatic fluids.
Synonyms
  1. Ca
  2. Calcium element
Chemical IUPAC Name calcium
Chemical Formula [Ca]2+
Chemical Structure Structure
Chemical Taxonomy
Kingdom
  • Inorganic
Super Class
  • Inorganic compounds
Class
  • Inorganic Ions and Gases
Sub Class
  • Metals
Family
  • Mammalian_Metabolite
Species
Biofunction
  • Essential minerals; Second messenger
Application
Source
  • Exogenous
Average Molecular Weight 40.078
Monoisotopic Molecular Weight 39.962589
Isomeric SMILES [Ca++]
Canonical SMILES [Ca++]
KEGG Compound ID C00076 Link Image
BioCyc ID CA%2b2 Link Image
BiGG ID 33764 Link Image
Wikipedia Link Calcium Link Image
METLIN ID Not Available
PubChem Compound 5460341 Link Image
PubChem Substance 8024986 Link Image
ChEBI ID 29320 Link Image
CAS Registry Number 7440-70-2
InChI Identifier InChI=1/Ca/q+2
Synthesis Reference Not Available
Melting Point (Experimental) 850 oC
Experimental Water Solubility Not Available Source: PhysProp
Predicted Water Solubility 399 mg/mL at 25 oC [MEYLAN,WM et al. (1996)] Calculated using ALOGPS
Physiological Charge 2
State Solid
Experimental LogP/Hydrophobicity Not Available Source: PhysProp
Predicted LogP/Hydrophobicity -0.57 [MEYLAN,WM & HOWARD,PH (1995)] Calculated using ALOGPS
Material Safety Data Sheet (MSDS) Not Available
MOL File Show Link Image
SDF File Show Link Image
PDB File Show Link Image
2D Structure
3D Structure
Experimental PDB ID Not Available
Experimental 1H NMR Spectrum Not Available
Experimental 13C NMR Spectrum Not Available
Experimental 13C HSQC Spectrum Not Available
Predicted 1H NMR Spectrum Not Available
Not Available
Predicted 13C NMR Spectrum Not Available
Not Available
Mass Spectrum Not Available
Simplified TOCSY Spectrum Not Available
BMRB Spectrum Not Available
Cellular Location
  • Cytoplasm (Predicted from LogP)
  • Extracellular
Biofluid Location
  • Rumen
  • Blood
  • Cow_Milk
Tissue Location Not Available
Concentrations (Normal)
Biofluid Rumen
Value 1000-4000 uM
Age N/A
Sex Both
Condition Normal
Breed Not Available
Experimental Condition Not Available
Comments An increase in the acidity of the ruminal fluidalso increased the absorption of phosphate, as did an increase in the ruminal Ca2 concentration over the range (1-4)mmol per litre.
References
Biofluid Rumen
Value 930.54 +/- 27.4 uM
Age N/A
Sex Female
Condition Normal
Breed Not Available
Experimental Condition Not Available
Comments Not Available
References
  • The rumen metabolome (in preparation)
Biofluid Rumen
Value 2500 +/- 2000 uM
Age N/A
Sex Female
Condition Normal
Breed Not Available
Experimental Condition Not Available
Comments Not Available
References
  • Metabolomics reveals unhealthy alterations in rumen metabolism with increased proportion of cereal grain in the diet of dairy cows. Burim N. Ametaj, Qendrim Zebeli, Fozia Saleem, Nikolaos Psychogios, Michael J. Lewis, Suzanna M. Dunn, Jianguo Xia and David S. Wishart Metabolomics 2010;6(4):583-594
Concentrations (Abnormal) Not Available
Pathway Names Not Available
HMDB Pathways Not Available
KEGG Pathways Not Available
SimCell Pathways Not Available
General References
  1. Wikipedia Link Image
Metabolic Enzymes
  1. Arylsulfatase A
  2. Primary amine oxidase, liver isozyme
  3. Glycerol-3-phosphate dehydrogenase, mitochondrial
  4. Membrane primary amine oxidase
  5. Primary amine oxidase, lung isozyme
  6. Heparanase
  7. Calcium-transporting ATPase type 2C member 1
  8. Ectonucleoside triphosphate diphosphohydrolase 8
  9. Ectonucleoside triphosphate diphosphohydrolase 1
  10. Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
  11. Platelet-activating factor acetylhydrolase IB subunit alpha
  12. N-acetylglucosamine-6-sulfatase
  13. Polypeptide N-acetylgalactosaminyltransferase 6
  14. Polypeptide N-acetylgalactosaminyltransferase 1
  15. Fumarylacetoacetase
  16. Fumarylacetoacetate hydrolase domain-containing protein 2
  17. Fumarylacetoacetate hydrolase domain-containing protein 1
  18. Glutamyl aminopeptidase
  19. UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
  20. Coagulation factor XIII A chain
  21. Matrix metallopeptidase 2 (Gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  22. Diacylglycerol kinase alpha
  23. Protein kinase C beta type
  24. Protein kinase C gamma type
  25. Protein kinase C alpha type
  26. Guanylyl cyclase-activating protein 1
  27. Glucosidase 2 subunit beta
  28. Calpain small subunit 1
  29. Calcineurin subunit B type 2
  30. Complement C1s subcomponent
  31. Alpha-lactalbumin
  32. Deoxyribonuclease-1
  33. Coagulation factor VII
  34. Arylsulfatase K
  35. Calpain-3
  36. Furin
  37. Coagulation factor IX
  38. Guanylyl cyclase-activating protein 2
  39. Coagulation factor X
  40. FK506-binding protein 10
  41. Calcineurin subunit B type 1
  42. Chymotrypsin-like elastase family member 1
  43. Calpain-1 catalytic subunit
  44. FK506-binding protein 9
  45. Annexin A1
  46. Hepatocyte growth factor-regulated tyrosine kinase substrate
  47. Calpain-2 catalytic subunit
Enzyme 1 [top]
Enzyme 1 ID 81
Enzyme 1 Name Arylsulfatase A
Enzyme 1 Synonyms
  1. ASA
  2. Cerebroside-sulfatase
Enzyme 1 Gene Name ARSA
Enzyme 1 Protein Sequence >Arylsulfatase A
MEALWTLTLALAAGLAAASPPNILLIFADDLGYGDLGSYGHPSSTTPNLDQLAAGGLRFT
DFYVPVSLCTPSRAALLTGRLPVRMGLYPGVLEPSSRGGLPLDEVTLAEVLAAQGYLTGI
AGKWHLGVGPEGAFLPPHHGFHRFLGIPYSHDQGPCQNLTCFPPATPCEGICDQGLVPIP
LLANLSVEAQPPWLPGLEARYVAFARDLMTDAQHQGRPFFLYYASHHTHYPQFSGQSFPG
HSGRGPFGDSLMELDAAVGALMTAVGDLGLLGETLVFFTADNGPETMRMSHGGCSGLLRC
GKGTTFEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAQLPNITLDGVDLSP
LLLGTGKSPRHTLFFYSAYPDEVRGVFAVRSGKYKAHFFTQGSVHSDTTADPACHASNPL
TAHEPPLLFDLSEDPGENYNLLDSVDEVAPEALQAVKQLELLKAQFDAAMTFGPSQMAQG
EDPTLQVCCQPSCTPRPSCCHCPEFQP
Enzyme 1 Number of Residues 507
Enzyme 1 Molecular Weight 53806.6
Enzyme 1 Theoretical pI 4.90
Enzyme 1 GO Classification
Function
Process
Component
Enzyme 1 General Function Inorganic ion transport and metabolism
Enzyme 1 Specific Function Hydrolyzes cerebroside sulfate
Enzyme 1 Pathways Not Available
Enzyme 1 Reactions Not Available
Enzyme 1 Pfam Domain Function
Enzyme 1 Signals
  • 1-18
Enzyme 1 Transmembrane Regions
  • None
Enzyme 1 Essentiality Not Available
Enzyme 1 GenBank ID Protein 115304931 Link Image
Enzyme 1 UniProtKB/Swiss-Prot ID Q08DD1 Link Image
Enzyme 1 UniProtKB/Swiss-Prot Entry Name ARSA_BOVIN Link Image
Enzyme 1 PDB ID Not Available
Enzyme 1 Cellular Location Not Available
Enzyme 1 Gene Sequence >1524 bp
ATGGAGGCTCTGTGGACCCTCACTCTGGCCTTGGCCGCAGGTCTGGCTGCTGCCAGCCCA
CCTAACATCCTGCTGATCTTTGCTGATGACCTGGGCTACGGGGACCTGGGCTCCTATGGG
CACCCCAGCTCCACCACTCCCAATCTGGACCAGTTGGCCGCAGGGGGTCTGCGGTTCACA
GACTTCTACGTGCCTGTGTCTCTGTGCACACCCTCCCGGGCTGCCCTCCTGACCGGCCGA
CTCCCAGTTCGGATGGGTTTGTACCCTGGAGTTCTGGAGCCCAGCTCCCGAGGGGGCCTG
CCCCTGGATGAGGTGACCTTGGCTGAGGTCCTGGCTGCCCAAGGCTACCTCACAGGGATA
GCTGGCAAGTGGCACCTTGGGGTGGGGCCTGAGGGGGCCTTTCTGCCCCCCCACCACGGC
TTCCATCGATTCCTGGGCATCCCATACTCCCATGACCAGGGCCCTTGCCAGAACCTGACC
TGCTTCCCCCCGGCCACCCCCTGCGAAGGCATCTGCGACCAGGGCCTGGTCCCTATCCCA
CTGTTGGCCAACCTGTCGGTGGAGGCACAGCCCCCTTGGCTGCCTGGACTCGAGGCTCGC
TACGTGGCCTTTGCCCGCGACCTCATGACTGACGCCCAACACCAAGGCCGCCCGTTCTTC
CTGTACTACGCCTCCCACCACACCCACTACCCCCAGTTCAGTGGGCAGAGCTTCCCAGGG
CACTCAGGCCGAGGGCCATTTGGGGACTCCCTGATGGAGCTGGACGCGGCTGTGGGGGCC
CTGATGACAGCTGTGGGGGACCTGGGGCTGCTTGGAGAGACGCTCGTCTTCTTCACTGCA
GACAACGGGCCTGAGACGATGCGGATGTCCCATGGTGGCTGCTCTGGCCTCCTGCGATGC
GGAAAAGGAACCACTTTCGAAGGGGGCGTCCGAGAGCCTGCCTTGGCCTTCTGGCCAGGT
CACATCGCTCCCGGTGTGACCCATGAGCTGGCCAGCTCCCTGGACCTGCTGCCCACCCTG
GCAGCCCTGGCGGGGGCCCAACTGCCCAATATCACCTTGGATGGCGTTGACCTCAGCCCC
CTGCTGTTGGGCACAGGCAAGAGCCCCCGGCACACCCTCTTCTTCTACTCGGCCTACCCG
GATGAGGTCCGAGGGGTCTTTGCAGTGCGGAGCGGGAAGTACAAGGCACACTTCTTTACC
CAGGGCTCTGTCCACAGCGACACCACTGCAGACCCTGCCTGCCACGCCTCTAATCCTCTG
ACTGCCCATGAGCCCCCGCTGCTCTTTGACCTGTCTGAGGACCCTGGTGAGAACTACAAC
CTTCTGGACAGTGTGGATGAGGTTGCCCCAGAGGCGCTGCAGGCAGTGAAGCAACTTGAG
CTGCTCAAGGCCCAGTTTGATGCTGCCATGACCTTCGGACCCAGCCAGATGGCGCAGGGT
GAGGACCCCACCCTGCAGGTCTGCTGCCAGCCCAGCTGCACCCCCCGGCCGTCCTGCTGC
CACTGCCCTGAGTTCCAGCCCTGA
Enzyme 1 GenBank Gene ID BC123816 Link Image
Enzyme 1 GeneCard ID ARSA Link Image
Enzyme 1 GenAtlas ID Not Available
Enzyme 1 HGNC ID Not Available
Enzyme 1 Chromosome Location Chromosome:2
Enzyme 1 Locus 22q13.31-qter|22q13.33
Enzyme 1 SNPs SNPJam Report Link Image
Enzyme 1 General References Not Available
Enzyme 1 Metabolite References Not Available
Enzyme 2 [top]
Enzyme 2 ID 91
Enzyme 2 Name Primary amine oxidase, liver isozyme
Enzyme 2 Synonyms
  1. Copper amine oxidase
  2. Amine oxidase [copper-containing]
  3. Serum amine oxidase
  4. SAO
Enzyme 2 Gene Name Not Available
Enzyme 2 Protein Sequence >Primary amine oxidase, liver isozyme
MFIFIFLSLWTLLVMGREEGGVGSEEGVGKQCHPSLPPRCPSRSPSDQPWTHPDQSQLFA
DLSREELTTVMSFLTQQLGPDLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPPA
REALAIVFFGGQPQPNVTELVVGPLPQPSYMRDVTVERHGGPLPYYRRPVLLREYLDIDQ
MIFNRELPQAAGVLHHCCSYKQGGQKLLTMNSAPRGVQSGDRSTWFGIYYNITKGGPYLH
PVGLELLVDHKALDPADWTVQKVFFQGRYYENLAQLEEQFEAGQVNVVVIPDDGTGGFWS
LKSQVPPGPTPPLQFHPQGPRFSVQGNRVASSLWTFSFGLGAFSGPRVFDVRFQGERLAY
EISLQEAGAVYGGNTPAAMLTRYMDSGFGMGYFATPLIRGVDCPYLATYMDWHFVVESQT
PKTLHDAFCVFEQNKGLPLRRHHSDFLSHYFGGVAQTVLVFRSVSTMLNYDYVWDMVFYP
NGAIEVKLHATGYISSAFLFGAARRYGNQVGEHTLGPVHTHSAHYKVDLDVGGLENWVWA
EDMAFVPTAIPWSPEHQIQRLQVTRKQLETEEQAAFPLGGASPRYLYLASKQSNKWGHPR
GYRIQTVSFAGGPMPQNSPMERAFSWGRYQLAITQRKETEPSSSSVFNQNDPWTPTVDFS
DFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDQEPSMDSAD
SIYFREGQDAGSCEINPLACLPQAATCAPDLPVFSHGGYPEY
Enzyme 2 Number of Residues 762
Enzyme 2 Molecular Weight 84756.1
Enzyme 2 Theoretical pI 5.82
Enzyme 2 GO Classification
Function
Process
Component
Enzyme 2 General Function Secondary metabolites biosynthesis, transport and catabolism
Enzyme 2 Specific Function RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2)
Enzyme 2 Pathways Not Available
Enzyme 2 Reactions Not Available
Enzyme 2 Pfam Domain Function
Enzyme 2 Signals
  • 1-16
Enzyme 2 Transmembrane Regions
  • None
Enzyme 2 Essentiality Not Available
Enzyme 2 GenBank ID Protein 546216 Link Image
Enzyme 2 UniProtKB/Swiss-Prot ID Q29437 Link Image
Enzyme 2 UniProtKB/Swiss-Prot Entry Name AOCX_BOVIN Link Image
Enzyme 2 PDB ID 1TU5 Link Image
Enzyme 2 PDB File Show
Enzyme 2 3D Structure
Enzyme 2 Cellular Location Not Available
Enzyme 2 Gene Sequence >2289 bp
ATGTTCATCTTCATTTTTCTGTCCTTGTGGACTCTTCTGGTGATGGGCAGGGAGGAAGGT
GGTGTTGGGAGTGAGGAGGGAGTTGGGAAGCAATGTCATCCCAGCCTGCCTCCCCGCTGC
CCCTCCAGATCCCCTAGTGACCAGCCCTGGACACACCCTGACCAGAGCCAGCTGTTTGCA
GACCTGAGCCGAGAAGAGCTGACAACTGTGATGAGCTTCCTGACTCAGCAGCTGGGGCCA
GACCTGGTGGATGCAGCCCAGGCCCGACCCTCAGACAACTGTGTCTTCTCGGTAGAACTT
CAGCTGCCCCCCAAGGCTGCAGCCCTGGCCCACCTGGACAGGGGGAGCCCCCCACCTGCC
CGGGAGGCACTGGCCATCGTCTTCTTTGGCGGACAACCCCAGCCCAATGTGACTGAGCTG
GTAGTGGGGCCGCTGCCCCAGCCCTCCTACATGCGGGATGTGACCGTGGAGCGTCATGGC
GGCCCCCTGCCCTATTACCGACGCCCCGTGCTTCTCCGAGAGTACCTGGACATAGACCAG
ATGATCTTCAACAGAGAGCTGCCCCAGGCTGCTGGTGTCCTGCACCACTGCTGCTCCTAC
AAACAAGGAGGACAGAAACTGTTGACCATGAACTCAGCTCCCCGTGGAGTGCAGTCAGGT
GATAGGTCCACTTGGTTTGGCATCTACTATAACATCACAAAGGGTGGGCCTTACCTGCAC
CCCGTGGGGTTGGAGCTTCTGGTAGACCATAAGGCTCTGGACCCTGCCGATTGGACCGTC
CAGAAGGTGTTCTTTCAAGGCCGCTACTATGAAAATCTGGCCCAGCTGGAGGAGCAGTTT
GAGGCTGGCCAGGTGAATGTGGTGGTGATCCCAGACGATGGCACAGGTGGGTTCTGGTCC
CTGAAGTCCCAGGTGCCTCCGGGTCCAACTCCCCCTCTGCAGTTCCATCCTCAGGGCCCC
CGCTTCAGTGTCCAGGGCAATCGAGTGGCCTCCTCATTGTGGACTTTCTCCTTTGGCCTC
GGAGCTTTCAGTGGTCCTAGGGTCTTTGACGTTCGATTCCAGGGAGAACGGCTGGCTTAT
GAGATCAGCCTGCAAGAGGCTGGTGCTGTCTACGGTGGGAATACTCCAGCAGCAATGCTC
ACTCGCTATATGGATAGTGGCTTTGGCATGGGTTACTTCGCCACACCCCTGATTCGTGGC
GTAGACTGCCCTTACCTGGCCACCTACATGGACTGGCACTTCGTTGTGGAGTCCCAAACC
CCCAAGACACTACATGATGCCTTTTGTGTGTTTGAGCAGAACAAGGGCCTGCCCCTGAGG
CGACACCACTCAGATTTTCTTTCCCACTATTTTGGGGGCGTTGCACAGACAGTGCTGGTC
TTCAGGTCTGTGTCCACGATGCTCAACTATGACTATGTGTGGGATATGGTCTTCTACCCC
AATGGGGCCATAGAAGTCAAATTGCATGCCACGGGCTACATCAGCTCAGCGTTCCTCTTT
GGTGCTGCCCGAAGATACGGAAACCAGGTTGGGGAACACACGCTGGGCCCCGTCCACACC
CACAGTGCCCACTACAAGGTGGATCTGGACGTGGGAGGACTGGAAAACTGGGTCTGGGCT
GAGGATATGGCTTTTGTCCCCACGGCGATACCCTGGAGCCCTGAGCACCAGATACAGAGG
CTGCAGGTGACCCGGAAGCAGCTGGAGACCGAGGAGCAGGCTGCCTTCCCCCTGGGAGGG
GCTTCCCCTCGCTACCTGTACCTGGCCAGCAAGCAGAGCAACAAGTGGGGGCACCCTCGC
GGCTATCGCATCCAGACCGTCAGCTTTGCTGGGGGGCCGATGCCCCAGAACAGCCCCATG
GAGAGAGCCTTCAGCTGGGGGAGGTACCAGCTGGCCATAACCCAGAGGAAGGAGACAGAG
CCCAGCAGCTCCAGCGTCTTCAATCAGAATGACCCCTGGACTCCCACCGTGGACTTTTCT
GACTTCATCAACAATGAGACCATTGCTGGAAAGGACTTGGTGGCCTGGGTGACAGCCGGT
TTCCTGCACATCCCACATGCAGAGGATATTCCCAACACGGTGACGGTGGGGAACGGTGTG
GGCTTCTTCTTGAGACCCTACAACTTCTTTGACCAGGAGCCCTCCATGGATTCTGCTGAC
TCCATCTACTTCCGGGAAGGCCAGGATGCTGGGTCCTGTGAGATCAACCCCCTGGCTTGC
CTGCCCCAGGCTGCTACCTGTGCCCCTGACCTCCCTGTCTTCTCCCACGGGGGCTACCCT
GAGTACTAG
Enzyme 2 GenBank Gene ID S69583 Link Image
Enzyme 2 GeneCard ID Not Available
Enzyme 2 GenAtlas ID Not Available
Enzyme 2 HGNC ID Not Available
Enzyme 2 Chromosome Location Not Available
Enzyme 2 Locus Not Available
Enzyme 2 SNPs SNPJam Report Link Image
Enzyme 2 General References
  1. [PubMed Link Image]
Enzyme 2 Metabolite References Not Available
Enzyme 3 [top]
Enzyme 3 ID 92
Enzyme 3 Name Glycerol-3-phosphate dehydrogenase, mitochondrial
Enzyme 3 Synonyms
  1. GPDH-M
  2. GPD-M
Enzyme 3 Gene Name GPD2
Enzyme 3 Protein Sequence >Glycerol-3-phosphate dehydrogenase, mitochondrial
MAFQKAVKGTILVGGGALATVLGLSHFAHYKRKQVNLAFVEAADCISEPVNREPPSREAQ
ILTLKNTSEFDVLVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVR
YLQKAIMKLDIEQYRMVKEALHERANLLEIAPHLSAPLPIMLPIYKWWQLPYYWVGIKLY
DLVAGSNCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYG
AATANYMEVMSLLKKTDPQTGKERVSGARCKDVLTGEEFDVRAKCVINATGPFTDTVRKM
DDKDTTAICQPSAGVHIVMPGYYSPESMGLLDPATSDGRVIFFLPWQKMTIAGTTDTPTD
VTHHPIPSEEDINFILNEVRNYLSCDVEVRRGDVLAAWSGIRPLVTDPKSADTKSISRNH
VVDISESGLITIAGGKWTTYRSMAEDTINAAVKAHNLKAGPSRTVGLFLQGGKDWSPTLY
IRLVQDYGLESEVAQHLAATYGDKAFEVAKMASVTGKRWPIVGVRLVSEFPYIEAEVKYG
IKEYACTAVDMISRRTRLAFLNVQAAEEALPRIVELMGRELNWDDSKKEEELETARKFLY
YEMGYKSRSEQLTDRSEISLLPSDIDRYKKRFHKFDADQKGFITIVDVQRVLESIGVQMD
ENTLHEILNEVDLNKNGQVELNEFLQLMSAIQKGRVSGSRLAILMKTAEENLDRRVPIPV
DRSCGGL
Enzyme 3 Number of Residues 727
Enzyme 3 Molecular Weight 80761.8
Enzyme 3 Theoretical pI 7.05
Enzyme 3 GO Classification
Function
Process
Component
Enzyme 3 General Function Energy production and conversion
Enzyme 3 Specific Function sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol
Enzyme 3 Pathways
  • Polyol metabolism
  • glycerol degradation via glycerol kinase pathway
  • glycerone phosphate from sn-glycerol 3-phosphate (aerobic route):step 1/1
Enzyme 3 Reactions Not Available
Enzyme 3 Pfam Domain Function
Enzyme 3 Signals
  • None
Enzyme 3 Transmembrane Regions
  • None
Enzyme 3 Essentiality Not Available
Enzyme 3 GenBank ID Protein 151553979 Link Image
Enzyme 3 UniProtKB/Swiss-Prot ID A6QLU1 Link Image
Enzyme 3 UniProtKB/Swiss-Prot Entry Name GPDM_BOVIN Link Image
Enzyme 3 PDB ID Not Available
Enzyme 3 Cellular Location Not Available
Enzyme 3 Gene Sequence >2184 bp
ATGGCATTTCAAAAGGCGGTGAAAGGGACTATTCTTGTTGGAGGAGGTGCTCTTGCCACT
GTTCTAGGCCTCTCTCATTTTGCTCATTACAAAAGGAAGCAAGTGAACCTGGCCTTTGTT
GAAGCAGCAGACTGCATTTCAGAACCTGTTAACAGGGAGCCTCCTTCCAGAGAAGCTCAG
ATACTGACTTTGAAAAACACATCTGAGTTCGATGTACTTGTCATCGGAGGAGGAGCGACA
GGAAGTGGCTGTGCCCTGGATGCGGTCACCAGAGGACTAAAAACAGCCCTTGTAGAAAGA
GATGATTTCTCATCGGGGACCAGCAGCAGAAGCACTAAATTGATCCATGGTGGTGTGAGA
TATCTTCAGAAGGCTATCATGAAGTTGGATATTGAGCAGTACAGGATGGTAAAAGAAGCC
CTTCATGAGCGTGCCAACCTGCTGGAAATTGCTCCCCATTTATCAGCTCCATTGCCTATT
ATGCTTCCAATTTACAAATGGTGGCAGTTACCATACTACTGGGTAGGAATCAAGCTATAT
GATCTGGTTGCTGGAAGTAATTGCCTGAAAAGCAGTTATGTCCTCAGCAAATCAAGAGCC
CTTGAGCATTTCCCAATGCTCCAGAAGGACAAACTGGTGGGAGCAATTGTCTACTATGAT
GGACAACACAACGACGCACGGATGAACCTTGCCATTGCTCTCACCGCTGCCAGGTATGGG
GCTGCCACGGCCAATTACATGGAGGTCATGAGTTTGCTCAAGAAGACAGACCCCCAGACA
GGGAAAGAGCGTGTGAGCGGTGCACGGTGTAAGGATGTGCTGACAGGGGAGGAATTTGAT
GTGAGAGCCAAGTGTGTTATCAATGCCACGGGACCTTTCACAGACACCGTGCGCAAAATG
GATGATAAGGACACCACAGCTATCTGCCAGCCGAGTGCTGGCGTCCACATCGTGATGCCT
GGTTACTACAGCCCAGAGAGCATGGGACTTCTTGACCCAGCGACCAGTGATGGGAGAGTT
ATTTTCTTCTTGCCCTGGCAAAAGATGACTATAGCTGGCACTACCGACACTCCAACTGAT
GTTACACACCATCCCATTCCTTCCGAAGAAGATATCAACTTCATTTTGAATGAAGTGCGT
AACTACTTGAGTTGTGATGTTGAAGTGAGAAGAGGGGATGTCCTGGCTGCGTGGAGCGGT
ATTCGCCCCCTTGTGACAGATCCCAAGTCTGCAGACACGAAGTCCATCTCCCGAAACCAT
GTCGTGGACATCAGCGAGAGTGGCCTTATCACCATAGCAGGTGGAAAGTGGACAACCTAT
CGATCTATGGCAGAAGATACCATAAATGCCGCAGTCAAGGCACACAATTTGAAAGCAGGA
CCAAGTAGAACAGTTGGGCTTTTCCTTCAGGGGGGCAAAGACTGGAGCCCCACACTCTAC
ATCAGGCTCGTCCAGGACTATGGACTTGAAAGTGAGGTGGCCCAGCATCTTGCCGCCACC
TATGGTGATAAGGCTTTTGAGGTGGCCAAGATGGCAAGTGTGACGGGAAAGCGGTGGCCC
ATTGTTGGGGTGCGTCTTGTGTCGGAATTTCCATACATTGAAGCAGAGGTGAAATACGGG
ATTAAGGAGTATGCTTGTACCGCTGTGGATATGATTTCACGTCGTACTCGCCTGGCCTTC
CTAAATGTGCAGGCGGCAGAGGAGGCCCTACCTAGGATTGTTGAATTGATGGGCCGAGAA
TTGAATTGGGATGATTCTAAAAAAGAGGAAGAACTTGAAACAGCCAGGAAGTTTCTATAT
TATGAAATGGGCTATAAATCTCGATCAGAACAGTTAACAGATCGCTCTGAAATTAGCCTA
CTGCCTTCAGACATTGACAGGTACAAGAAGAGATTTCATAAATTCGATGCAGACCAGAAA
GGCTTTATTACCATTGTTGATGTTCAACGTGTATTAGAGAGTATCGGCGTCCAAATGGAT
GAAAATACGCTACATGAAATTTTGAATGAAGTAGATTTGAATAAAAATGGACAGGTTGAA
CTCAATGAATTTTTGCAGCTGATGAGTGCTATTCAAAAAGGAAGGGTGTCTGGAAGCCGG
CTCGCTATACTCATGAAAACTGCCGAAGAAAATCTCGATAGAAGAGTTCCCATCCCTGTG
GACCGAAGTTGTGGAGGATTGTGA
Enzyme 3 GenBank Gene ID BC148085 Link Image
Enzyme 3 GeneCard ID GPD2 Link Image
Enzyme 3 GenAtlas ID Not Available
Enzyme 3 HGNC ID Not Available
Enzyme 3 Chromosome Location Chromosome:2
Enzyme 3 Locus 2q24.1
Enzyme 3 SNPs SNPJam Report Link Image
Enzyme 3 General References Not Available
Enzyme 3 Metabolite References Not Available
Enzyme 4 [top]
Enzyme 4 ID 95
Enzyme 4 Name Membrane primary amine oxidase
Enzyme 4 Synonyms
  1. Copper amine oxidase
  2. Semicarbazide-sensitive amine oxidase
  3. SSAO
  4. Vascular adhesion protein 1
  5. VAP-1
Enzyme 4 Gene Name AOC3
Enzyme 4 Protein Sequence >Membrane primary amine oxidase
MNQKTTLVLLALAVITIFALVCVLIAGRGGDGGEASQPHYCPSGTPSVQPWTHPGQNQLF
ADLSREELTAVMSFLTQKLGPDLVDAAQARPSDNCIFSVELQLPPKAAALAHLDRRSPPP
AREALAIVFFGGQPQPNVTELVVGPLPQPSYMRDVTVERHGGPLPYYRRPVLLREYLDID
QMIFNRELPQAAGVLHHCCSYKQGGGNLVTMTTAPRGLQSGDRATWFGLYYNISGAGYYL
HPVGLELLVDHKALDPAQWTIQKVFFQGRYYESLAQLEEQFEAGRVNVVVIPNNGTGGSW
SLKSQVPPGPTPPLQFHPQGTRFSVQGSRVTSSLWTFSFGLGAFSGPRIFDIRFQGERLA
YEISLQEAVAIYGGNTPAAMLTRYMDGCFGMGKFATPLTRGVDCPYLATYVDWHFLLESQ
APRTLHDAFCVFEQNKGLPLRRHHSDFISQYFGGVVETVLVFRSVSTLLNYDYVWDMVFH
PNGAIEVKFHATGYISSAFFFGTAQKYGNQVRENTLGTVHTHSAHYKVDLDVGGLENWVW
AEDMAFVPTTVPWSPEHQIQRLQVTRKQLETEEQAAFPLGGASPRYLYLASKQSNKWGHP
RGYRIQTVSFAGRPLPQNSSTERAISWGRYQLAVTQRKETEPSSSSVFNQNDPWTPTVDF
ADFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSINSA
DSIYFQKHQDAGSCEVNSLACLPKDPACAPDLPAFSHGGFFTN
Enzyme 4 Number of Residues 763
Enzyme 4 Molecular Weight 84499.9
Enzyme 4 Theoretical pI 6.51
Enzyme 4 GO Classification
Function
Process
Component
Enzyme 4 General Function Secondary metabolites biosynthesis, transport and catabolism
Enzyme 4 Specific Function Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin- independent fashion. Has a monoamine oxidase activity
Enzyme 4 Pathways Not Available
Enzyme 4 Reactions Not Available
Enzyme 4 Pfam Domain Function
Enzyme 4 Signals
  • None
Enzyme 4 Transmembrane Regions
  • 7-27
Enzyme 4 Essentiality Not Available
Enzyme 4 GenBank ID Protein 6682825 Link Image
Enzyme 4 UniProtKB/Swiss-Prot ID Q9TTK6 Link Image
Enzyme 4 UniProtKB/Swiss-Prot Entry Name AOC3_BOVIN Link Image
Enzyme 4 PDB ID Not Available
Enzyme 4 Cellular Location Not Available
Enzyme 4 Gene Sequence >2292 bp
ATGAACCAGAAGACCACCCTGGTGCTCCTTGCTCTGGCTGTCATCACCATCTTTGCCTTG
GTGTGTGTCTTAATAGCTGGCAGGGGAGGAGATGGGGGTGAAGCCAGCCAACCTCACTAC
TGCCCCTCCGGAACCCCCAGTGTCCAGCCCTGGACACACCCTGGCCAGAACCAGCTGTTT
GCAGACCTGAGCCGAGAAGAGCTGACAGCTGTGATGAGCTTCCTGACCCAGAAGCTGGGG
CCAGACCTGGTGGATGCAGCCCAGGCCCGACCCTCTGACAACTGCATCTTCTCGGTAGAG
CTGCAGCTGCCCCCCAAGGCTGCAGCCCTGGCCCACCTGGACAGGAGGAGCCCCCCACCT
GCCCGGGAGGCACTGGCCATCGTCTTCTTTGGTGGACAACCCCAGCCCAATGTGACTGAG
CTGGTGGTGGGGCCGCTGCCCCAGCCCTCCTACATGCGGGATGTGACCGTGGAGCGTCAT
GGGGGCCCCCTGCCCTATTACCGACGCCCCGTGCTTCTCCGAGAGTACCTGGACATAGAC
CAGATGATCTTCAACAGAGAGCTGCCCCAGGCTGCTGGTGTCCTGCACCACTGCTGCTCC
TACAAACAAGGAGGAGGGAACCTGGTGACCATGACCACAGCCCCCCGCGGTTTGCAATCA
GGTGACCGGGCCACCTGGTTTGGCCTCTACTACAACATCTCAGGGGCTGGGTACTATCTG
CACCCTGTGGGGTTAGAGCTGCTGGTAGATCACAAGGCTCTGGACCCTGCCCAGTGGACC
ATCCAGAAGGTGTTCTTTCAAGGCCGCTACTATGAAAGTCTGGCCCAGCTGGAGGAGCAG
TTTGAGGCTGGCCGGGTGAATGTGGTGGTGATCCCAAACAATGGCACAGGTGGGTCCTGG
TCCCTGAAGTCCCAGGTGCCCCCGGGTCCAACTCCACCTCTGCAGTTCCATCCTCAGGGC
ACCCGCTTCAGTGTCCAGGGCAGTCGAGTGACCTCCTCATTGTGGACTTTCTCCTTTGGC
CTCGGAGCTTTCAGTGGTCCTAGGATCTTTGACATTCGATTCCAAGGAGAACGACTGGCT
TATGAGATCAGCCTGCAAGAGGCCGTGGCTATTTATGGTGGGAATACCCCAGCAGCAATG
CTCACTCGCTATATGGATGGCTGCTTTGGCATGGGCAAGTTCGCCACGCCCCTGACCCGA
GGGGTGGACTGCCCCTATCTGGCCACCTATGTGGACTGGCACTTCCTTCTGGAGTCTCAA
GCCCCCAGGACCCTACATGATGCCTTTTGTGTGTTTGAGCAGAACAAGGGCCTGCCCCTG
AGGCGACACCACTCAGATTTTATTTCCCAGTATTTTGGGGGCGTTGTGGAGACAGTGCTG
GTCTTCAGATCTGTGTCAACCTTGCTCAACTATGACTATGTGTGGGATATGGTCTTTCAC
CCCAATGGGGCCATAGAAGTCAAATTCCATGCCACGGGCTATATCAGCTCAGCGTTCTTC
TTTGGTACTGCCCAAAAATACGGAAACCAGGTTCGGGAGAATACACTGGGCACCGTCCAC
ACCCACAGTGCCCACTACAAGGTGGATCTGGATGTGGGAGGACTGGAGAACTGGGTCTGG
GCTGAGGACATGGCTTTTGTCCCCACAACGGTACCCTGGAGCCCTGAGCACCAGATACAG
AGGCTGCAGGTGACCCGGAAGCAGCTGGAGACTGAGGAGCAGGCCGCCTTCCCCCTGGGA
GGGGCCTCCCCTCGCTACCTGTACCTGGCCAGCAAGCAGAGCAACAAGTGGGGGCACCCT
CGCGGCTATCGCATCCAGACGGTCAGCTTTGCTGGGAGGCCGCTGCCCCAGAACAGCTCC
ACAGAGAGAGCCATCAGCTGGGGGAGGTACCAGCTGGCCGTGACCCAGAGGAAGGAGACA
GAGCCCAGCAGCTCCAGCGTCTTCAATCAGAATGACCCCTGGACTCCCACTGTGGACTTT
GCTGACTTCATCAACAATGAGACCATTGCTGGAAAGGACTTGGTGGCCTGGGTGACAGCC
GGTTTCCTGCACATCCCTCATGCAGAGGACATTCCCAACACAGTGACAGTGGGGAACGGT
GTGGGCTTCTTTCTGCGACCCTACAACTTCTTTGATGAGGACCCCTCCATCAATTCTGCT
GACTCAATCTACTTCCAAAAACACCAGGATGCTGGGTCCTGTGAGGTCAACTCCCTGGCT
TGTCTGCCCAAGGATCCTGCCTGTGCCCCTGATCTCCCTGCCTTCTCCCACGGGGGCTTC
TTCACCAATTAG
Enzyme 4 GenBank Gene ID AB019242 Link Image
Enzyme 4 GeneCard ID AOC3 Link Image
Enzyme 4 GenAtlas ID Not Available
Enzyme 4 HGNC ID Not Available
Enzyme 4 Chromosome Location Chromosome:1
Enzyme 4 Locus 17q21
Enzyme 4 SNPs SNPJam Report Link Image
Enzyme 4 General References
  1. [PubMed Link Image]
Enzyme 4 Metabolite References Not Available
Enzyme 5 [top]
Enzyme 5 ID 96
Enzyme 5 Name Primary amine oxidase, lung isozyme
Enzyme 5 Synonyms
  1. Copper amine oxidase
  2. Amine oxidase [copper-containing]
  3. BOLAO
Enzyme 5 Gene Name Not Available
Enzyme 5 Protein Sequence >Primary amine oxidase, lung isozyme
MFIFIFLSLWTLLVMGREEGGVGSEEGVGKQCHPSLPPRCPSRSPSDQPWTHPDQSQLFA
DLSREELTAVMSFLTQKLGPDLVDAAQARPSDNCIFSVELQLPPKAAALAHLDRRSPPPA
REALAIVFFGGQPQPNVTELVVGPLPQPSYMRDVTVERHGGPLPYYRHTVLLREYLDIDQ
MIFNRELPQAAGVLHHCCSYKQGGGNLVTMTTAPPGLQSGDRATWFGLYYNISKAGYYLH
PVGLELLVDHKALDPAQWTIQKVFFQGRYYESLVQLEEQFEAGRVNVVVIPNNGTGGSWS
LKSQVPPGPTPPLQFHPQGTRFSVQGSRVTSSLWTFSFGLGAFSGPRIFDIRFQGERLAY
EISLQEAVAIYGGNTPAAMLTRYMDACFGMGKFATPLTRGVDCPYLATYVDWHFLLESQA
PKTLHDAFCVFEQNKGLPLRRHHSDFISQYFGGVVETVLVFRSVSTLLNYDYVWDMVFHP
NGAIEVKFHVTGYISSAFFFGTAQKYGNQVRENTLGTVHTHSAHYKVDLDVGGLENWVWA
EDMAFVPTTVPWSPEHQIQRLQVIRKQLETEEQAAFPLGGGSPRYLYLASKQSNKWGHPR
GYRIQTVSFAGRPLPQNSSTERAISWGRYQLAVTQRKETEPSSSSVFNQNDPWTPTVDFA
DFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDQEPSMDSAD
SIYFREGQDAGSCEINPLACLPQAATCAPDLPVFSHGGYPEY
Enzyme 5 Number of Residues 762
Enzyme 5 Molecular Weight 84882.4
Enzyme 5 Theoretical pI 6.16
Enzyme 5 GO Classification
Function
Process
Component
Enzyme 5 General Function Secondary metabolites biosynthesis, transport and catabolism
Enzyme 5 Specific Function RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2)
Enzyme 5 Pathways Not Available
Enzyme 5 Reactions Not Available
Enzyme 5 Pfam Domain Function
Enzyme 5 Signals
  • 1-16
Enzyme 5 Transmembrane Regions
  • None
Enzyme 5 Essentiality Not Available
Enzyme 5 GenBank ID Protein 2665358 Link Image
Enzyme 5 UniProtKB/Swiss-Prot ID O46406 Link Image
Enzyme 5 UniProtKB/Swiss-Prot Entry Name AOCY_BOVIN Link Image
Enzyme 5 PDB ID 1TU5 Link Image
Enzyme 5 PDB File Show
Enzyme 5 3D Structure
Enzyme 5 Cellular Location Not Available
Enzyme 5 Gene Sequence >2289 bp
ATGTTCATCTTCATTTTTCTGTCCTTGTGGACTCTTCTGGTGATGGGCAGGGAGGAAGGT
GGTGTTGGGAGTGAGGAGGGAGTTGGGAAGCAATGTCATCCCAGCCTGCCTCCCCGCTGC
CCCTCCAGATCCCCTAGTGACCAGCCCTGGACACACCCTGACCAGAGCCAGCTGTTTGCA
GACCTGAGCCGAGAAGAGCTGACAGCTGTGATGAGCTTCCTGACCCAGAAGCTGGGGCCA
GACCTGGTGGATGCAGCCCAGGCCCGACCCTCTGACAACTGCATCTTCTCGGTAGAGCTG
CAGCTGCCCCCCAAGGCTGCAGCCCTGGCCCACCTGGACAGGAGGAGCCCCCCACCTGCC
CGGGAGGCACTGGCCATCGTCTTCTTTGGTGGACAACCCCAGCCCAATGTGACTGAGCTG
GTGGTGGGGCCGCTGCCCCAGCCCTCCTACATGCGGGATGTGACCGTGGAGCGTCATGGG
GGCCCCCTGCCCTATTACCGACACACCGTGCTTCTCCGAGAGTACCTGGACATAGACCAG
ATGATCTTCAACAGAGAGCTGCCCCAGGCTGCTGGTGTCCTGCACCACTGCTGCTCCTAC
AAACAAGGAGGAGGGAACCTGGTGACCATGACTACAGCCCCCCCCGGTTTGCAATCAGGT
GACCGGGCCACCTGGTTTGGCCTCTACTACAACATCTCAAAGGCTGGGTACTATCTGCAC
CCTGTGGGGTTAGAGCTGCTGGTAGATCACAAGGCTCTGGACCCTGCCCAGTGGACCATC
CAGAAGGTGTTCTTTCAAGGCCGCTACTATGAAAGTCTGGTCCAGCTGGAGGAGCAGTTT
GAGGCTGGCCGGGTGAATGTGGTGGTGATCCCAAACAATGGCACAGGTGGGTCCTGGTCC
CTGAAGTCCCAGGTGCCCCCGGGTCCAACTCCACCTCTGCAGTTCCATCCTCAGGGCACC
CGCTTCAGTGTCCAGGGCAGTCGAGTGACCTCCTCATTGTGGACTTTCTCCTTTGGCCTC
GGAGCTTTCAGTGGTCCTAGGATCTTTGACATTCGATTCCAAGGAGAACGACTGGCTTAT
GAGATCAGCCTGCAAGAGGCCGTGGCTATTTATGGTGGGAATACTCCAGCAGCAATGCTC
ACTCGCTATATGGATGCCTGCTTTGGCATGGGCAAGTTCGCCACGCCCCTGACCCGAGGG
GTGGACTGCCCCTATCTGGCCACCTATGTGGACTGGCACTTCCTTCTGGAGTCTCAAGCC
CCCAAGACCCTACATGATGCCTTTTGTGTGTTTGAGCAGAACAAGGGCCTGCCCCTGAGG
CGACACCACTCAGATTTTATTTCCCAGTATTTTGGGGGCGTTGTGGAGACAGTGCTGGTC
TTCAGATCTGTGTCAACCTTGCTCAACTATGACTATGTGTGGGATATGGTCTTTCACCCC
AATGGGGCCATAGAAGTCAAATTCCATGTCACGGGCTATATCAGCTCAGCGTTCTTCTTT
GGTACTGCCCAAAAATACGGAAACCAGGTTCGGGAGAATACACTGGGCACCGTCCACACC
CACAGTGCCCACTACAAGGTGGATCTGGATGTGGGAGGACTGGAGAACTGGGTCTGGGCT
GAGGACATGGCTTTTGTCCCCACAACGGTACCCTGGAGCCCTGAGCACCAGATACAGAGG
CTGCAGGTGATCCGGAAGCAGCTGGAGACTGAGGAGCAGGCCGCCTTCCCCCTGGGAGGG
GGTTCCCCTCGCTACCTGTACCTGGCCAGCAAGCAGAGCAACAAGTGGGGGCACCCTCGC
GGGTATCGCATCCAGACGGTCAGCTTTGCTGGGAGGCCGCTGCCCCAGAACAGCTCCACA
GAGAGAGCCATCAGCTGGGGGAGGTACCAGCTGGCCGTGACCCAGAGGAAGGAGACAGAG
CCCAGCAGCTCCAGCGTCTTCAATCAGAATGACCCCTGGACTCCCACTGTGGACTTTGCT
GACTTCATCAACAATGAGACCATTGCTGGAAAGGACTTGGTGGCCTGGGTGACAGCCGGT
TTCCTGCACATCCCACATGCAGAGGATATTCCCAACACGGTGACGGTGGGGAACGGTGTG
GGCTTCTTCTTGAGACCCTACAACTTCTTTGACCAGGAGCCCTCCATGGATTCTGCTGAC
TCCATCTACTTCCGGGAAGGCCAGGATGCTGGGTCCTGTGAGATCAACCCCCTGGCTTGT
CTGCCCCAGGCTGCTACCTGTGCCCCTGACCTCCCTGTCTTCTCCCACGGGGGCTACCCT
GAGTACTAG
Enzyme 5 GenBank Gene ID Y15774 Link Image
Enzyme 5 GeneCard ID Not Available
Enzyme 5 GenAtlas ID Not Available
Enzyme 5 HGNC ID Not Available
Enzyme 5 Chromosome Location Not Available
Enzyme 5 Locus Not Available
Enzyme 5 SNPs SNPJam Report Link Image
Enzyme 5 General References
  1. [PubMed Link Image]
Enzyme 5 Metabolite References Not Available
Enzyme 6 [top]
Enzyme 6 ID 115
Enzyme 6 Name Heparanase
Enzyme 6 Synonyms
  1. Heparanase 8 kDa subunit
  2. Heparanase 50 kDa subunit
Enzyme 6 Gene Name HPSE
Enzyme 6 Protein Sequence >Heparanase
MLACRKPGLRPPLLLLLPLLGPLGPCSPGTPAAAAPADDAAELEFFTERPLHLVSPAFLS
FTIDANLATDPRFFTFLGSSKLRTLARGLAPAYLRFGGNKGDFLIFDPKKEPAFEERSYW
LSQSNQDICKSGSIPSDVEEKLRLEWPFQEQVLLREQYQKKFTNSTYSRSSVDMLYTFAS
CSGLNLIFGVNALLRTTDMHWDSSNAQLLLDYCSSKNYNISWELGNEPNSFQRKAGIFIN
GRQLGEDFIEFRKLLGKSAFKNAKLYGPDIGQPRRNTVKMLKSFLKAGGEVIDSVTWHHY
YVNGRIATKEDFLNPDILDTFISSVQKTLRIVEKIRPLKKVWLGETSSAFGGGAPFLSNT
FAAGFMWLDKLGLSARMGIEVVMRQVLFGAGNYHLVDGNFEPLPDYWLSLLFKKLVGNKV
LMASVKGPDRSKFRVYLHCTNTKHPRYKEGDLTLYALNLHNVTKHLELPHHLFNKQVDKY
LIKPSGTDGLLSKSVQLNGQILKMVDEQTLPALTEKPLHPGSSLGMPPFSYGFFVIRNAK
VAACI
Enzyme 6 Number of Residues 545
Enzyme 6 Molecular Weight 61076.0
Enzyme 6 Theoretical pI 9.61
Enzyme 6 GO Classification
Function
Process
Component
Enzyme 6 General Function Involved in calcium ion binding
Enzyme 6 Specific Function Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Contributes to metastasis and angiogenesis
Enzyme 6 Pathways Not Available
Enzyme 6 Reactions Not Available
Enzyme 6 Pfam Domain Function
Enzyme 6 Signals
  • 1-37
Enzyme 6 Transmembrane Regions
  • None
Enzyme 6 Essentiality Not Available
Enzyme 6 GenBank ID Protein 13606095 Link Image
Enzyme 6 UniProtKB/Swiss-Prot ID Q9MYY0 Link Image
Enzyme 6 UniProtKB/Swiss-Prot Entry Name HPSE_BOVIN Link Image
Enzyme 6 PDB ID Not Available
Enzyme 6 Cellular Location Not Available
Enzyme 6 Gene Sequence Not Available
Enzyme 6 GenBank Gene ID AF281160 Link Image
Enzyme 6 GeneCard ID HPSE Link Image
Enzyme 6 GenAtlas ID Not Available
Enzyme 6 HGNC ID Not Available
Enzyme 6 Chromosome Location Chromosome:4
Enzyme 6 Locus 4q21.3
Enzyme 6 SNPs SNPJam Report Link Image
Enzyme 6 General References
  1. [PubMed Link Image]
Enzyme 6 Metabolite References Not Available
Enzyme 7 [top]
Enzyme 7 ID 153
Enzyme 7 Name Calcium-transporting ATPase type 2C member 1
Enzyme 7 Synonyms
  1. ATPase 2C1
  2. Secretory pathway Ca(2+)-transporting ATPase
Enzyme 7 Gene Name ATP2C1
Enzyme 7 Protein Sequence >Calcium-transporting ATPase type 2C member 1
MDNLLPQSRFSYFKKYPIHAIRKYLSMLRNQKEEEQVARFQKIPNAENETMIPVLTSKKA
SELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIML
LLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLMPPECHCVREGK
LEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSVDESSLTGETTPCSKVTAPQPAAT
NGDLASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLG
KQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMV
KKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLRAEVTGVGYNPFGEV
IVDGDVVHGFYNPSVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQDY
IRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYHSKGQTLTLTQQQ
RDLYQQEKAQMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSI
KMITGDSQETAVAIASRLGLYSKTSQSVSGEEIDAMDVQQLSQIVPKVAVFYRASPRHKM
KIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIM
SAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPA
QSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVITPR
DTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQK
VFQTESLSILDLLFLLGLTSSVCIVAEIIKKVERSREKIQKPVSSTSSSFLEV
Enzyme 7 Number of Residues 953
Enzyme 7 Molecular Weight 104779.3
Enzyme 7 Theoretical pI 7.01
Enzyme 7 GO Classification
Function
Process
Component
Enzyme 7 General Function Inorganic ion transport and metabolism
Enzyme 7 Specific Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium
Enzyme 7 Pathways Not Available
Enzyme 7 Reactions Not Available
Enzyme 7 Pfam Domain Function
Enzyme 7 Signals
  • None
Enzyme 7 Transmembrane Regions
  • 105-125 139-157 297-316 329-346 734-753 764-784 805-824 843-862 876-894 910-930
Enzyme 7 Essentiality Not Available
Enzyme 7 GenBank ID Protein 7595749 Link Image
Enzyme 7 UniProtKB/Swiss-Prot ID P57709 Link Image
Enzyme 7 UniProtKB/Swiss-Prot Entry Name AT2C1_BOVIN Link Image
Enzyme 7 PDB ID Not Available
Enzyme 7 Cellular Location Not Available
Enzyme 7 Gene Sequence >2862 bp
ATGGATAATCTGTTGCCTCAGTCAAGATTCTCTTATTTCAAAAAATATCCTATCCATGCA
ATTAGAAAATATTTATCGATGCTGAGAAACCAAAAAGAAGAAGAACAGGTTGCACGTTTT
CAAAAAATTCCTAATGCTGAAAATGAGACAATGATTCCGGTATTGACATCAAAAAAAGCA
AGTGAATTACCAGTCAGTGAAGTTGCAAGCATTCTCCAAGCTGATCTTCAGAATGGTCTA
AACAAATGTGAAGTAAGTCATAGGAGAGCCTTCCATGGCTGGAATGAGTTTGATATCAGT
GAAGATGAGCCACTATGGAAGAAGTATATTTCTCAGTTTAAAAATCCCCTTATTATGCTG
CTTCTGGCTTCTGCAGTCATCAGTGTTTTAATGCATCAGTTTGATGATGCTGTCAGTATC
ACTGTGGCAATACTTATTGTTGTTACGGTCGCCTTCGTTCAGGAATATCGTTCAGAAAAA
TCTCTTGAAGAACTAAGTAAACTTATGCCACCAGAATGCCATTGTGTGCGTGAAGGAAAA
TTGGAGCATACACTTGCACGAGACTTAGTTCCAGGTGATACAGTTTGCCTTTCAGTTGGG
GACAGGGTTCCTGCTGACTTGCGCTTGTTTGAGGCTGTGGATCTTTCTGTTGATGAGTCC
AGCTTGACAGGAGAGACAACACCTTGTTCTAAGGTGACAGCTCCTCAGCCGGCTGCTACT
AATGGAGATCTTGCATCAAGAAGTAACATTGCCTTCATGGGAACACTGGTCAGATGTGGC
AAAGCAAAGGGTATTGTCATTGGAACAGGAGAAAATTCTGAATTCGGAGAAGTTTTTAAA
ATGATGCAAGCAGAAGAAGCACCAAAAACCCCTCTGCAGAAGAGCATGGACCTCTTAGGA
AAACAACTTTCCTTTTACTCCTTTGGTATAATAGGTATCATCATGTTGGTTGGCTGGTTG
CTAGGAAAAGACATATTGGAAATGTTTACTATTAGTGTAAGTTTGGCTGTAGCAGCAATT
CCTGAAGGTCTTCCCATTGTGGTCACAGTGACTCTAGCCCTTGGTGTTATGAGAATGGTG
AAGAAGAGGGCGATTGTGAAAAAACTACCTATTGTTGAAACTCTGGGTTGCTGTAATGTG
ATTTGTTCAGATAAGACTGGAACCCTGACCAAGAATGAAATGACTGTTACCCACATATTT
ACTTCGGATGGCCTGCGTGCTGAGGTTACTGGAGTTGGCTACAATCCATTTGGGGAAGTG
ATTGTTGATGGTGATGTTGTTCATGGATTCTATAACCCATCTGTTAGTAGAATTGTTGAG
GCTGGCTGTGTGTGCAATGATGCTGTAATTAGAAATAACACTCTAATGGGGAAACCAACG
GAAGGAGCCTTAATTGCTCTTGCAATGAAGATGGGTCTTGATGGACTTCAACAGGATTAT
ATCAGAAAAGCTGAATACCCTTTTAGCTCTGAGCAGAAGTGGATGGCTGTTAAGTGTGTG
CACCGAACACAGCAGGACAGACCAGAGATTTGTTTTATGAAGGGTGCTTATGAACAGGTG
ATTAAGTATTGTACTACATATCACAGCAAAGGACAGACCTTGACACTCACCCAGCAGCAG
AGAGATCTGTACCAGCAAGAGAAGGCCCAGATGGGCTCTGCAGGGCTCAGAGTTCTTGCT
TTGGCTTCTGGTCCTGAATTGGGACAACTGACGTTCCTTGGCCTGGTGGGAATCATTGAT
CCTCCTAGAACTGGTGTGAAAGAAGCCGTTACAACACTCATTGCCTCAGGAGTATCAATA
AAAATGATTACTGGAGACTCACAGGAGACTGCAGTTGCCATCGCTAGTCGTCTGGGATTA
TATTCCAAAACCTCCCAGTCAGTCTCAGGAGAAGAAATAGATGCAATGGATGTCCAGCAG
CTTTCACAAATAGTGCCAAAGGTTGCAGTATTTTACAGAGCTAGCCCAAGGCATAAGATG
AAAATTATCAAGTCTCTGCAGAAGAATGGGTCAGTTGTGGCCATGACAGGAGATGGAGTA
AATGATGCAGTTGCTCTGAAGGCTGCAGACATTGGAGTTGCGATGGGTCAGACTGGCACA
GATGTTTGCAAAGAGGCAGCTGACATGATCCTGGTGGATGATGATTTCCAAACCATCATG
TCTGCAATTGAAGAGGGTAAAGGGATTTATAATAACATTAAAAATTTTGTTAGATTCCAG
CTGAGCACGAGTATAGCAGCATTAACTTTAATCTCACTGGCTACATTAATGAACTTTCCC
AATCCTCTCAATGCCATGCAGATTTTGTGGATCAATATTATTATGGATGGACCTCCAGCT
CAGAGCCTTGGAGTAGAACCAGTGGATAAAGATGTCATTCGTAAACCTCCACGCAACTGG
AAAGACAGCATTTTGACCAAAAACCTGATACTTAAAATACTTGTTTCCTCAATAATCATT
GTTTGTGGGACTTTGTTTGTCTTCTGGCGGGAGCTGCGAGACAATGTGATAACACCTCGG
GACACAACAATGACTTTCACGTGCTTTGTGTTTTTTGACATGTTCAATGCACTGAGTTCC
AGATCTCAGACCAAATCTGTGTTTGAGATTGGACTCTGCAGTAATAAAATGTTTTGCTAT
GCAGTTCTTGGATCCATCATGGGACAGTTATTAGTTATTTACTTTCCTCCACTTCAGAAA
GTTTTTCAGACTGAGAGCCTAAGTATACTGGATTTACTGTTTCTTCTGGGTCTCACCTCG
TCAGTGTGCATAGTGGCAGAAATTATCAAGAAGGTTGAAAGGAGCAGAGAGAAGATCCAG
AAGCCTGTTAGCTCGACATCATCGTCTTTTCTTGAAGTATGA
Enzyme 7 GenBank Gene ID AF230532 Link Image
Enzyme 7 GeneCard ID ATP2C1 Link Image
Enzyme 7 GenAtlas ID Not Available
Enzyme 7 HGNC ID Not Available
Enzyme 7 Chromosome Location Chromosome:3
Enzyme 7 Locus 3q22.1
Enzyme 7 SNPs SNPJam Report Link Image
Enzyme 7 General References Not Available
Enzyme 7 Metabolite References Not Available
Enzyme 8 [top]
Enzyme 8 ID 156
Enzyme 8 Name Ectonucleoside triphosphate diphosphohydrolase 8
Enzyme 8 Synonyms
  1. E-NTPDase 8
  2. NTPDase 8
  3. NTPDase8
Enzyme 8 Gene Name ENTPD8
Enzyme 8 Protein Sequence >Ectonucleoside triphosphate diphosphohydrolase 8
MGLTWKQRVFTALLGAAAVSGLTALLLVLVGTMNVLLPPDTKFGIVFDAGSSHTSLFVYQ
WPANKENDTGIVSQALACQAEGPGISSYASNPARVGESLQGCLEEALALIPKAKHHETPM
FLGATAGMRLLSRKNRSQAEDVFAAVSRALGQSPVDFRGAELLTGQDEGAFGWITINYIL
GLLVKYSFSGEWIRPLEETLVGALDMGGASTQITFVPGGPILDKTAQATFRLYGADHTVY
THSYLCFGRDQALSRVLAELVQASTGLLIRHPCYHSGYRGTLALASLYESPCAPAAPPDL
SQNLTVEGTGNPGACVEALRKLFNFSSCDGREDCAFAGVYQPPVQGQFYAFSNFYYTFNF
LNLTSKPSLSGANATIWEFCLRPWKLVEASAPPGQDRWLRDYCASGLYILTLLVEGYGFS
EETWGGIEFRQQAGGADIGWTLGYMLNLTNLIPAEAPAQGWAQSFGVWAAGVVFVVLTLA
ATLGAVAVQVFWLQD
Enzyme 8 Number of Residues 495
Enzyme 8 Molecular Weight 53239.2
Enzyme 8 Theoretical pI 4.97
Enzyme 8 GO Classification
Function
Process
Component
Enzyme 8 General Function Not Available
Enzyme 8 Specific Function Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolyzis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP
Enzyme 8 Pathways Not Available
Enzyme 8 Reactions Not Available
Enzyme 8 Pfam Domain Function
Enzyme 8 Signals
  • None
Enzyme 8 Transmembrane Regions
  • 9-29 467-487
Enzyme 8 Essentiality Not Available
Enzyme 8 GenBank ID Protein 117306525 Link Image
Enzyme 8 UniProtKB/Swiss-Prot ID A0JND9 Link Image
Enzyme 8 UniProtKB/Swiss-Prot Entry Name ENTP8_BOVIN Link Image
Enzyme 8 PDB ID Not Available
Enzyme 8 Cellular Location Not Available
Enzyme 8 Gene Sequence >1488 bp
ATGGGGCTGACCTGGAAGCAGCGGGTCTTCACGGCTCTGCTGGGCGCAGCAGCGGTCTCA
GGCCTCACCGCGCTGCTTCTCGTCCTGGTGGGGACCATGAACGTCCTCCTGCCTCCAGAC
ACCAAGTTTGGGATCGTGTTCGACGCTGGGTCCTCCCACACATCCCTCTTTGTGTATCAG
TGGCCGGCCAACAAGGAGAACGACACCGGCATAGTCAGCCAGGCCCTGGCCTGCCAGGCG
GAAGGGCCTGGAATCTCGTCTTACGCCTCCAACCCTGCGCGGGTTGGCGAGAGCCTGCAG
GGCTGCCTGGAGGAGGCGCTAGCACTGATCCCAAAGGCCAAGCATCATGAGACACCCATG
TTCCTGGGGGCCACTGCAGGCATGCGGCTGCTCAGCCGCAAGAATCGCTCCCAGGCGGAG
GACGTGTTCGCCGCGGTCAGCCGGGCCCTGGGCCAGTCACCGGTGGACTTCCGGGGCGCA
GAGCTCCTGACGGGGCAGGACGAAGGCGCCTTTGGTTGGATCACCATCAACTACATCCTT
GGCCTGCTGGTGAAGTACTCCTTCTCTGGAGAGTGGATCCGGCCCCTGGAGGAGACGCTG
GTGGGCGCCCTGGACATGGGTGGGGCCTCCACCCAGATTACCTTTGTACCTGGAGGCCCC
ATCCTGGACAAGACCGCCCAGGCCACCTTCCGCCTCTACGGTGCCGACCACACCGTCTAC
ACCCACAGCTACCTCTGCTTCGGGCGCGACCAGGCGCTGAGCAGGGTGCTGGCCGAGCTG
GTGCAGGCCAGCACGGGCCTCCTGATCCGCCACCCCTGCTACCACAGCGGCTACCGGGGC
ACGCTGGCCCTGGCGTCCCTGTATGAGTCGCCCTGCGCCCCGGCAGCGCCCCCCGACCTC
AGCCAGAACCTCACCGTGGAGGGCACGGGGAACCCCGGGGCCTGCGTCGAGGCCCTCCGG
AAGCTCTTCAATTTCTCCAGCTGTGACGGCCGAGAAGACTGTGCCTTCGCCGGGGTCTAC
CAGCCCCCCGTGCAGGGCCAGTTCTACGCTTTCTCCAACTTCTACTACACCTTCAACTTC
CTGAACCTCACCTCCAAGCCGTCACTGAGTGGGGCCAACGCCACCATCTGGGAGTTCTGC
CTGCGGCCCTGGAAGCTGGTGGAGGCGAGCGCGCCCCCGGGCCAGGACCGCTGGCTGCGG
GACTACTGTGCCTCGGGCCTATACATCCTCACGCTCCTGGTCGAGGGCTACGGGTTCAGT
GAGGAGACCTGGGGAGGCATCGAGTTCCGCCAGCAGGCCGGCGGCGCTGACATCGGCTGG
ACGCTGGGCTACATGCTGAACCTGACCAACCTGATCCCGGCCGAGGCGCCCGCCCAGGGT
TGGGCACAGAGCTTCGGCGTCTGGGCGGCCGGGGTCGTCTTCGTGGTGCTGACGCTCGCG
GCCACCCTGGGTGCCGTGGCAGTGCAGGTCTTCTGGCTCCAGGACTAG
Enzyme 8 GenBank Gene ID BC126637 Link Image
Enzyme 8 GeneCard ID ENTPD8 Link Image
Enzyme 8 GenAtlas ID Not Available
Enzyme 8 HGNC ID Not Available
Enzyme 8 Chromosome Location Chromosome:9
Enzyme 8 Locus 9q34.3
Enzyme 8 SNPs SNPJam Report Link Image
Enzyme 8 General References Not Available
Enzyme 8 Metabolite References Not Available
Enzyme 9 [top]
Enzyme 9 ID 163
Enzyme 9 Name Ectonucleoside triphosphate diphosphohydrolase 1
Enzyme 9 Synonyms
  1. NTPDase 1
  2. Ecto-ATP diphosphohydrolase
  3. ATPDase
  4. Lymphoid cell activation antigen
  5. Ecto-apyrase
  6. CD39 antigen
Enzyme 9 Gene Name ENTPD1
Enzyme 9 Protein Sequence >Ectonucleoside triphosphate diphosphohydrolase 1
MEDRRESELKVFCSKNILSILGFSCIIAVIALLALGLTQNKALPENVKFGIVLDAGSSHT
SLYIYRWPAEKENDTGVVTQIEESNVKGPGISGFAKKVNEINVYLTACMERAQKVIPSIQ
HMETPVYLGATAGMRLLRMENKQMADKILAAVASSISEYPFDFQGARIISGQEEGAYGWI
TVNYLLGKFTQKLSWFNLKPSKDDTQETYGALDLGGASTQITFVPQNETTESPNNNLYFR
LYGKNYSVYTHSFLCYGKDQALLQKLALGLQGTNGIIHEPCFHSRYMRKIKMSVLNEGFC
TKRHELNSSFYPLVDIEIRGAGNFQRCRQSIIQLFNTSYCPYSSCSFNGVFLPPLHGQFG
AFSAFYYVMEFLNLTSEESVSVEQLTEKLEEFCAQRWEEVQKNFGEVKEKYLSEYCFSGT
YILVLLLNGYHFTAESWKNIHFMNKVRSTDVGWTLGYMLNLTNKIPAEEPMSPPLPHSTY
VFLMVLFSLILLAVIIVGIVVFHKPSYFWKDMV
Enzyme 9 Number of Residues 513
Enzyme 9 Molecular Weight 58113.4
Enzyme 9 Theoretical pI 6.88
Enzyme 9 GO Classification
Function
Process
Component
Enzyme 9 General Function Involved in ATP binding
Enzyme 9 Specific Function In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well
Enzyme 9 Pathways Not Available
Enzyme 9 Reactions Not Available
Enzyme 9 Pfam Domain Function
Enzyme 9 Signals
  • None
Enzyme 9 Transmembrane Regions
  • 17-37 482-502
Enzyme 9 Essentiality Not Available
Enzyme 9 GenBank ID Protein 2240205 Link Image
Enzyme 9 UniProtKB/Swiss-Prot ID O18956 Link Image
Enzyme 9 UniProtKB/Swiss-Prot Entry Name ENTP1_BOVIN Link Image
Enzyme 9 PDB ID Not Available
Enzyme 9 Cellular Location Not Available
Enzyme 9 Gene Sequence >1542 bp
ATGGAAGATAGAAGGGAATCTGAACTGAAGGTATTTTGCTCTAAAAACATACTGAGCATA
CTTGGTTTCTCCTGCATCATCGCTGTGATAGCATTGCTCGCTCTGGGGCTGACCCAGAAC
AAAGCACTGCCAGAAAATGTTAAGTTTGGGATTGTGCTGGATGCGGGCTCCTCTCATACG
AGTTTGTACATCTATAGATGGCCGGCAGAGAAGGAGAATGACACGGGGGTGGTGACTCAG
ATAGAAGAATCGAACGTTAAAGGTCCCGGAATCTCAGGCTTTGCTAAAAAAGTAAATGAA
ATCAATGTTTATCTGACGGCATGCATGGAAAGAGCCCAGAAAGTGATTCCGTCAATCCAG
CACATGGAAACACCTGTGTACCTGGGAGCCACGGCCGGCATGCGGTTGCTCCGGATGGAA
AATAAACAGATGGCAGACAAGATCCTGGCTGCAGTTGCAAGCAGCATCAGCGAGTACCCC
TTTGACTTCCAAGGTGCCAGAATCATCAGTGGCCAGGAGGAAGGTGCCTATGGCTGGATT
ACTGTCAACTATTTGCTGGGCAAATTCACTCAGAAATTGAGTTGGTTTAACCTGAAGCCA
AGCAAAGACGACACTCAGGAAACCTATGGAGCTTTAGACCTTGGGGGAGCCTCTACACAA
ATCACTTTTGTGCCCCAAAATGAAACGACCGAGTCTCCAAACAACAACCTGTACTTCCGC
CTCTATGGCAAGAACTACAGTGTATACACACACAGCTTCCTGTGCTATGGGAAGGACCAA
GCACTTTTGCAGAAACTGGCCCTGGGACTTCAGGGTACAAATGGAATCATCCATGAGCCA
TGCTTTCACTCAAGATACATGAGGAAAATAAAGATGAGCGTCTTAAACGAAGGTTTCTGT
ACCAAGAGACATGAGTTGAATTCTTCATTTTATCCACTCGTTGACATTGAAATCCGTGGC
GCTGGAAACTTCCAACGATGTCGGCAAAGCATCATTCAACTCTTTAACACCAGTTACTGC
CCTTACTCCAGTTGCTCCTTCAATGGGGTTTTCTTGCCGCCACTCCATGGGCAGTTTGGG
GCATTTTCAGCTTTTTACTATGTGATGGAGTTTTTAAACCTTACATCAGAGGAATCAGTA
TCTGTGGAACAGTTGACTGAGAAGTTGGAAGAGTTCTGCGCACAGCGTTGGGAAGAGGTG
CAGAAGAATTTTGGTGAAGTGAAGGAGAAATACCTGAGTGAATACTGCTTTTCTGGCACC
TACATCCTGGTTCTCCTCCTGAATGGCTACCATTTTACAGCTGAGTCCTGGAAAAATATT
CACTTCATGAACAAGGTCCGGAGCACCGACGTTGGGTGGACTTTGGGCTACATGCTGAAC
CTGACCAACAAGATTCCAGCTGAAGAGCCAATGTCCCCACCCCTCCCCCACTCCACCTAT
GTCTTCCTCATGGTCCTCTTCTCCCTGATCCTGCTCGCAGTGATCATCGTAGGCATAGTT
GTCTTTCACAAGCCTTCGTATTTCTGGAAAGACATGGTATAG
Enzyme 9 GenBank Gene ID AF005940 Link Image
Enzyme 9 GeneCard ID ENTPD1 Link Image
Enzyme 9 GenAtlas ID Not Available
Enzyme 9 HGNC ID Not Available
Enzyme 9 Chromosome Location Chromosome:1
Enzyme 9 Locus 10q24
Enzyme 9 SNPs SNPJam Report Link Image
Enzyme 9 General References
  1. [PubMed Link Image]
Enzyme 9 Metabolite References Not Available
Enzyme 10 [top]
Enzyme 10 ID 207
Enzyme 10 Name Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Enzyme 10 Synonyms
  1. SERCA1
  2. Calcium pump 1
  3. Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform
  4. SR Ca(2+)-ATPase 1
  5. Endoplasmic reticulum class 1/2 Ca(2+) ATPase
Enzyme 10 Gene Name ATP2A1
Enzyme 10 Protein Sequence >Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
MEAAHSKTTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVLEQFEDL
LVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILTIKSTTLRVDQSIL
TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKAIGIVATTGVGTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDRIDGDLCLLNEFSVTGSTYAPEGEVLKNDKPVRSGQYDGLVELATICALC
NDSSLDFNETKGIYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPV
KEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSTKFMEYETDLTFVGVVGMLD
PPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEDVADRAYTGREFDDL
PLAEQREACRRACCFARVEPTHKSKIVEYLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRTPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFLYAEDGPHVTYSQLTHFMKCSEHSPDFEGVDCEVFEAPQPMTMAL
SVLVTIEMCNALNSLSENQSLVRMPPWVNIWLVGSIGLSMSLHFLILYVDPLPMIFKLQA
LDLYHWLMVLKISLPVIGLDEILKFVARNYLEG
Enzyme 10 Number of Residues 993
Enzyme 10 Molecular Weight 109289.4
Enzyme 10 Theoretical pI 4.93
Enzyme 10 GO Classification
Function
Process
Component
Enzyme 10 General Function Inorganic ion transport and metabolism
Enzyme 10 Specific Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction
Enzyme 10 Pathways Not Available
Enzyme 10 Reactions Not Available
Enzyme 10 Pfam Domain Function
Enzyme 10 Signals
  • None
Enzyme 10 Transmembrane Regions
  • 49-69 90-110 254-273 296-313 757-776 787-807 828-850 897-916 930-948 964-984
Enzyme 10 Essentiality Not Available
Enzyme 10 GenBank ID Protein 111304645 Link Image
Enzyme 10 UniProtKB/Swiss-Prot ID Q0VCY0 Link Image
Enzyme 10 UniProtKB/Swiss-Prot Entry Name AT2A1_BOVIN Link Image
Enzyme 10 PDB ID 1XP5 Link Image
Enzyme 10 PDB File Show
Enzyme 10 3D Structure
Enzyme 10 Cellular Location Not Available
Enzyme 10 Gene Sequence >2982 bp
ATGGAGGCTGCGCACTCCAAGACCACAGAAGAATGTTTGGCCTATTTTGGGGTGAGCGAA
ACTACAGGCCTCACCCCGGACCAAGTTAAGCGGCATCTGGAGAAATATGGCCATAATGAG
CTCCCTGCTGAGGAGGGGAAGTCCCTGTGGGAGCTGGTGTTAGAGCAGTTTGAAGACCTC
CTGGTGCGGATCCTTCTCCTGGCCGCCTGCATTTCCTTTGTGCTGGCCTGGTTTGAGGAA
GGCGAAGAGACTGTCACCGCCTTTGTTGAACCCTTTGTCATCCTCTTGATCCTCATTGCC
AATGCCATCGTGGGGGTTTGGCAGGAGCGGAATGCAGAGAATGCCATCGAGGCTCTGAAG
GAATATGAACCCGAGATGGGGAAGGTCTACCGGGCTGACCGCAAGTCAGTACAAAGGATC
AAAGCTCGGGATATTGTTCCTGGAGACATCGTGGAGGTGGCTGTGGGGGACAAGGTCCCG
GCAGATATCCGCATCCTCACCATCAAGTCTACCACCCTCCGGGTCGACCAGTCCATCCTG
ACAGGCGAGTCTGTCTCTGTCATCAAGCACACAGAACCTGTTCCCGACCCCCGAGCTGTC
AACCAGGATAAGAAGAACATGCTTTTCTCGGGCACCAACATCGCAGCCGGCAAGGCCATC
GGCATTGTGGCCACCACCGGTGTGGGCACCGAGATTGGGAAGATCCGTGACCAAATGGCC
GCCACAGAGCAGGACAAGACCCCTCTGCAGCAAAAGCTGGATGAGTTTGGGGAGCAGCTC
TCCAAGGTCATCTCCCTCATCTGCGTGGCCGTCTGGCTCATCAACATTGGCCACTTCAAC
GACCCCGTGCATGGGGGCTCCTGGATCCGTGGTGCCATCTACTACTTTAAGATCGCCGTG
GCCCTGGCTGTGGCTGCCATCCCCGAGGGCCTTCCTGCAGTCATCACCACCTGCCTGGCC
TTGGGCACCCGCCGGATGGCAAAGAAGAACGCGATCGTGAGGAGCCTGCCCTCCGTGGAG
ACTCTGGGCTGCACCTCTGTCATCTGTTCCGACAAGACGGGCACCCTCACCACCAACCAG
ATGTCTGTCTGCAAGATGTTCATCATCGACAGGATAGATGGGGACCTCTGCCTGCTGAAC
GAGTTCTCTGTCACTGGCTCCACTTACGCTCCTGAAGGAGAGGTCTTGAAGAATGATAAG
CCAGTCCGCTCAGGGCAGTATGACGGGCTGGTGGAGCTGGCCACCATTTGTGCCCTCTGC
AATGACTCCTCCTTGGACTTCAATGAGACCAAAGGTATTTATGAGAAGGTGGGAGAGGCC
ACCGAGACAGCCCTCACCACCCTGGTGGAGAAGATGAATGTATTCAACACTGAAGTGAGA
AACCTCTCGAAGGTAGAGAGGGCCAACGCCTGCAACTCGGTGATCCGCCAGCTAATGAAG
AAGGAATTCACCCTGGAGTTCTCCCGGGACCGAAAGTCCATGTCTGTCTATTGCTCTCCA
GCAAAATCCCGGGCTGCTGTGGGCAATAAGATGTTTGTCAAGGGTGCCCCTGAGGGGGTC
ATCGATCGCTGTAACTACGTGCGAGTGGGCACCACCCGGGTGCCCATGACAGGGCCGGTG
AAGGAGAAGATTCTGTCGGTGATCAAAGAGTGGGGTACTGGCCGGGACACCCTGCGCTGC
CTGGCGCTGGCCACTCGGGACACCCCCCCCAAGCGAGAGGAGATGGTCCTGGATGACTCT
ACCAAGTTCATGGAGTACGAGACGGACTTGACATTCGTTGGCGTCGTGGGCATGCTGGAC
CCGCCCCGCAAGGAGGTCATGGGCTCCATCCAACTATGCCGAGACGCTGGAATCCGAGTA
ATCATGATCACCGGAGACAACAAGGGCACGGCCATTGCCATCTGCCGACGGATTGGCATC
TTCGGGGAGAACGAGGATGTGGCTGACCGGGCCTACACTGGCCGGGAGTTCGATGACCTG
CCCCTGGCCGAGCAGCGGGAGGCCTGCCGACGCGCCTGCTGCTTCGCCCGCGTGGAGCCC
ACCCACAAGTCGAAGATCGTGGAGTATCTGCAGTCCTTCGATGAGATCACGGCGATGACA
GGTGATGGCGTCAATGACGCCCCTGCGCTGAAGAAGGCGGAAATCGGCATTGCCATGGGA
TCCGGCACTGCCGTGGCCAAGACAGCCTCTGAGATGGTGCTGGCCGACGACAACTTCTCC
ACCATTGTGGCTGCCGTGGAGGAGGGCCGGGCCATCTACAACAACATGAAGCAGTTTATC
CGCTACCTCATCTCCTCCAACGTGGGCGAGGTGGTCTGCATCTTCCTGACAGCTGCCCTG
GGGCTGCCCGAGGCCCTGATCCCTGTGCAGCTGCTGTGGGTGAACCTGGTGACCGATGGG
CTCCCAGCCACAGCCCTGGGCTTCAACCCCCCAGACCTGGACATCATGGACCGGCCCCCC
CGGACCCCCAAGGAGCCCCTCATCAGTGGCTGGCTCTTCTTCCGCTACATGGCAATTGGG
GGCTATGTGGGTGCAGCCACCGTGGGAGCAGCGGCCTGGTGGTTCCTGTATGCTGAGGAC
GGGCCTCACGTCACCTACAGCCAGCTGACTCACTTCATGAAGTGCTCGGAGCACAGCCCA
GACTTCGAGGGTGTGGACTGTGAGGTCTTCGAGGCCCCGCAGCCCATGACCATGGCCTTG
TCTGTGCTGGTCACCATCGAGATGTGCAATGCTCTCAACAGCCTGTCTGAGAATCAGTCC
CTCGTGCGGATGCCACCCTGGGTGAACATCTGGCTGGTGGGCTCCATCGGCCTCTCCATG
TCCCTCCACTTCCTCATCCTCTACGTGGACCCTCTGCCGATGATCTTCAAGCTCCAAGCC
CTGGACCTGTACCATTGGCTCATGGTCCTCAAGATCTCATTACCAGTCATTGGGCTCGAC
GAAATCCTCAAGTTCGTTGCTCGAAACTACCTGGAGGGATAA
Enzyme 10 GenBank Gene ID BC119938 Link Image
Enzyme 10 GeneCard ID ATP2A1 Link Image
Enzyme 10 GenAtlas ID Not Available
Enzyme 10 HGNC ID Not Available
Enzyme 10 Chromosome Location Chromosome:1
Enzyme 10 Locus 16p12.1
Enzyme 10 SNPs SNPJam Report Link Image
Enzyme 10 General References Not Available
Enzyme 10 Metabolite References Not Available
Enzyme 11 [top]
Enzyme 11 ID 231
Enzyme 11 Name Platelet-activating factor acetylhydrolase IB subunit alpha
Enzyme 11 Synonyms
  1. PAF acetylhydrolase 45 kDa subunit
  2. PAF-AH 45 kDa subunit
  3. PAF-AH alpha
  4. PAFAH alpha
  5. Lissencephaly-1 protein
  6. LIS-1
Enzyme 11 Gene Name PAFAH1B1
Enzyme 11 Protein Sequence >Platelet-activating factor acetylhydrolase IB subunit alpha
MVLSQRQRDELNRAIADYLRSNGYEAAYSVFKKEAELDMNEELDKKYAGLLEKKWTSVIR
LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF
SVMVSASEDATIKVWDYETGDFERTLKGHTDSVEDISFDHSGKLLASCSADMTIKLWDFQ
GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV
RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE
TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK
TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR
Enzyme 11 Number of Residues 410
Enzyme 11 Molecular Weight 46612.7
Enzyme 11 Theoretical pI 7.40
Enzyme 11 GO Classification
Function
Process
Component
Enzyme 11 General Function Involved in dynactin binding
Enzyme 11 Specific Function Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein- mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing. Required for pronuclear migration during fertilization. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet- activating factor (PAF) by removing the acetyl group at the SN-2 position
Enzyme 11 Pathways Not Available
Enzyme 11 Reactions Not Available
Enzyme 11 Pfam Domain Function
Enzyme 11 Signals
  • None
Enzyme 11 Transmembrane Regions
  • None
Enzyme 11 Essentiality Not Available
Enzyme 11 GenBank ID Protein 551618 Link Image
Enzyme 11 UniProtKB/Swiss-Prot ID P43033 Link Image
Enzyme 11 UniProtKB/Swiss-Prot Entry Name LIS1_BOVIN Link Image
Enzyme 11 PDB ID 1UUJ Link Image
Enzyme 11 PDB File Show
Enzyme 11 3D Structure
Enzyme 11 Cellular Location Not Available
Enzyme 11 Gene Sequence >1233 bp
ATGGTGCTGTCCCAGAGACAACGAGATGAACTAAATCGAGCTATAGCAGATTATCTTCGT
TCAAATGGCTACGAAGCCGCATATTCAGTTTTTAAAAAGGAAGCTGAATTAGATATGAAT
GAAGAATTAGATAAGAAATATGCTGGTCTTTTGGAAAAAAAATGGACATCTGTTATTAGA
TTACAAAAGAAGGTTATGGAATTAGAATCAAAGTTAAATGAAGCAAAAGAAGAATTTACG
TCGGGTGGACCTCTTGGTCAGAAAAGAGACCCAAAAGAATGGATTCCCCGTCCACCAGAA
AAATATGCATTGAGTGGTCATAGGAGTCCAGTCACTCGAGTCATTTTCCATCCTGTGTTC
AGTGTTATGGTCTCTGCTTCAGAGGATGCTACAATTAAGGTGTGGGATTATGAGACTGGA
GATTTTGAACGAACTCTTAAGGGGCATACAGACTCTGTAGAGGATATTTCATTCGACCAC
AGTGGCAAGCTTCTGGCTTCATGTTCTGCAGATATGACCATTAAGCTATGGGATTTTCAG
GGCTTTGAATGCATCAGAACCATGCATGGCCATGACCACAATGTTTCTTCAGTAGCCATC
ATGCCCAATGGAGATCATATAGTGTCTGCCTCAAGGGATAAAACTATAAAAATGTGGGAA
GTGCAAACTGGCTACTGTGTGAAGACATTCACAGGACACAGAGAATGGGTACGTATGGTG
CGGCCAAATCAAGACGGCACTCTGATAGCCAGCTGTTCCAATGACCAGACTGTGCGTGTA
TGGGTCGTAGCAACAAAGGAATGCAAGGCTGAGCTTCGAGAACATGAGCATGTGGTAGAA
TGCATTTCCTGGGCTCCTGAAAGCTCATATTCTTCCATCTCTGAAGCAACAGGATCTGAG
ACTAAAAAAAGTGGCAAACCTGGGCCATTCTTACTGTCCGGATCCAGGGACAAGACTATC
AAGATGTGGGATGTCAGTACTGGCATGTGCCTTATGACCCTGGTGGGTCATGATAACTGG
GTACGTGGAGTTCTGTTCCATTCTGGGGGGAAGTTTATTTTGAGTTGCGCTGATGACAAG
ACCCTGCGCGTGTGGGATTACAAGAACAAGCGATGCATGAAGACCCTCAATGCGCATGAA
CACTTTGTTACCTCCTTGGATTTCCATAAGACGGCCCCATATGTGGTTACTGGCAGTGTA
GATCAAACAGTAAAGGTGTGGGAGTGTCGTTGA
Enzyme 11 GenBank Gene ID D30615 Link Image
Enzyme 11 GeneCard ID PAFAH1B1 Link Image
Enzyme 11 GenAtlas ID Not Available
Enzyme 11 HGNC ID Not Available
Enzyme 11 Chromosome Location Chromosome:1
Enzyme 11 Locus 17p13.3
Enzyme 11 SNPs SNPJam Report Link Image
Enzyme 11 General References
  1. [PubMed Link Image]
Enzyme 11 Metabolite References Not Available
Enzyme 12 [top]
Enzyme 12 ID 380
Enzyme 12 Name N-acetylglucosamine-6-sulfatase
Enzyme 12 Synonyms
  1. G6S
  2. Glucosamine-6-sulfatase
Enzyme 12 Gene Name GNS
Enzyme 12 Protein Sequence >N-acetylglucosamine-6-sulfatase
MRLLSLAPDRPRRGGPRHLTSGSPALPPPPPLLLLLLLLGGCLGVSGAAKSSRRPNVVLL
LADDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNLHVVNN
TLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLGHVPLGWSYW
YALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNSEPFFMMISTP
APHSPWTAAPQYQNAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKR
WQTLLSVDDLVEKLVKRLEFNGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPL
LVRGPGIKPNQTSKMLVANIDLGPTILDIAGYSLNKTQMDGMSFLPILKGASNLTWRSDV
LVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSERWNLQYCEFDDQ
EVFVEVYNLTADPHQLNNIAKSIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDP
RLMFSNHGSVRTRRFSKHLL
Enzyme 12 Number of Residues 560
Enzyme 12 Molecular Weight 62775.2
Enzyme 12 Theoretical pI 8.54
Enzyme 12 GO Classification
Function
Process
Component
Enzyme 12 General Function Inorganic ion transport and metabolism
Enzyme 12 Specific Function Hydrolysis of the 6-sulfate groups of the N- acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate
Enzyme 12 Pathways Not Available
Enzyme 12 Reactions Not Available
Enzyme 12 Pfam Domain Function
Enzyme 12 Signals
  • 1-48
Enzyme 12 Transmembrane Regions
  • None
Enzyme 12 Essentiality Not Available
Enzyme 12 GenBank ID Protein 94534741 Link Image
Enzyme 12 UniProtKB/Swiss-Prot ID Q1LZH9 Link Image
Enzyme 12 UniProtKB/Swiss-Prot Entry Name GNS_BOVIN Link Image
Enzyme 12 PDB ID Not Available
Enzyme 12 Cellular Location Not Available
Enzyme 12 Gene Sequence >1683 bp
ATGCGGCTCCTGTCTCTGGCCCCAGATAGGCCCCGGCGAGGCGGCCCTCGCCACCTGACC
TCCGGGAGCCCCGCGCTACCGCCGCCGCCGCCGCTGCTGCTGCTGCTGCTGCTGCTAGGT
GGTTGCCTGGGGGTCTCCGGGGCGGCGAAGAGCTCTCGGAGGCCCAATGTGGTGCTGCTT
CTTGCTGATGACCAGGACGAAGTGCTTGGTGGCATGACACCACTGAAGAAAACCAAGGCT
CTCATTGGAGAAATGGGAATGACTTTCTCCAGTGCTTATGTGCCAAGTGCTCTCTGCTGC
CCAAGCCGAGCCAGCATCCTGACAGGGAAGTACCCACACAATCTTCACGTGGTTAACAAC
ACTCTGGAGGGAAACTGCAGTAGTAAGTCCTGGCAGAAGATCCAAGAACCGAATACTTTC
CCAGCAATTCTCAGATCAATGTGTGGTTATCAGACCTTTTTTGCAGGGAAATACTTAAAT
GAGTATGGAGCCCCAGATGCAGGTGGACTCGGACACGTTCCTCTGGGCTGGAGTTACTGG
TATGCATTGGAAAAGAATTCTAAATATTATAATTACACCCTGTCTATCAATGGGAAGGCA
CGGAAGCATGGTGAGAACTACAGTGTGGACTACCTGACAGATGTCTTGGCCAATGTCTCC
TTGGACTTCCTGGACTACAAGTCCAACTCCGAGCCATTCTTCATGATGATCTCCACCCCA
GCGCCTCATTCGCCATGGACAGCTGCACCTCAATACCAAAACGCCTTCCAGAACGTCTTT
GCACCAAGAAACAAGAACTTCAACATCCATGGAACGAACAAGCACTGGTTAATTCGGCAA
GCCAAGACCCCAATGACTAATTCTTCAATACAGTTTTTAGATAATGCATTTAGGAAAAGG
TGGCAGACTCTGCTCTCAGTGGATGACCTCGTGGAGAAGCTGGTCAAGCGATTGGAGTTC
AATGGGGAGCTCAACAACACCTACATCTTTTATACCTCAGACAACGGCTATCACACAGGA
CAGTTTTCTTTGCCAATAGACAAAAGACAGCTGTATGAGTTTGATATAAAAGTTCCACTA
TTGGTTCGAGGGCCTGGGATCAAACCAAATCAGACAAGCAAGATGCTCGTTGCCAACATT
GACTTGGGCCCTACTATTCTGGACATTGCGGGCTATAGCCTGAATAAGACCCAGATGGAT
GGGATGTCTTTTTTGCCCATTTTGAAAGGGGCCAGTAATCTGACTTGGCGATCAGACGTC
CTGGTGGAATATCAGGGAGAAGGCCGCAACGTCACTGACCCCACGTGTCCTTCCCTGAGT
CCTGGAGTGTCTCAATGCTTCCCTGACTGTGTGTGTGAAGATGCATATAACAACACCTAT
GCCTGTGTGAGGACCATGTCAGAACGGTGGAACTTACAATACTGCGAGTTTGATGACCAG
GAGGTGTTTGTAGAAGTCTATAACCTGACTGCAGACCCACACCAACTCAATAACATTGCT
AAAAGCATAGATCCAGAGCTGCTGGGAAAGATGAACTATCGGCTGATGATGTTACAGTCC
TGCTCTGGACCAACCTGCCGCACTCCAGGGGTCTTTGACCCCGGGTATAGATTTGACCCT
CGGCTTATGTTCAGCAATCATGGCAGCGTCAGGACACGAAGATTTTCAAAACACCTTCTG
TAG
Enzyme 12 GenBank Gene ID BC115990 Link Image
Enzyme 12 GeneCard ID GNS Link Image
Enzyme 12 GenAtlas ID Not Available
Enzyme 12 HGNC ID Not Available
Enzyme 12 Chromosome Location Chromosome:1
Enzyme 12 Locus 12q14
Enzyme 12 SNPs SNPJam Report Link Image
Enzyme 12 General References Not Available
Enzyme 12 Metabolite References Not Available
Enzyme 13 [top]
Enzyme 13 ID 381
Enzyme 13 Name Polypeptide N-acetylgalactosaminyltransferase 6
Enzyme 13 Synonyms
  1. Polypeptide GalNAc transferase 6
  2. pp-GaNTase 6
  3. GalNAc-T6
  4. Protein-UDP acetylgalactosaminyltransferase 6
  5. UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6
Enzyme 13 Gene Name GALNT6
Enzyme 13 Protein Sequence >Polypeptide N-acetylgalactosaminyltransferase 6
MRLLRRRHMAVRLVMVGSAFVLFLFILQRDVSGREQATEKPWLRSLVSQKDHVLDLMLGA
VHNLRDSMPKFQIRAPEPQQTLASTNQSCLPGFYTPAELKPFWERPPQDPNGPGADGKAF
QKKEWTPQETQEKEEGYKKHCFNAFASDRISLQRALGPDTRPPECVDQKFRRCPPLPATS
VIIVFHNEAWSTLLRTVYSVLHTTPAILLKEIILVDDASTDEYLKEPLERYVKQLQVVQV
VRQQERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDETVVVSPNIVT
IDLNTFEFSKPVQRGRVQSRGNFDWSLTFGWEVLPAREKQRRKDETYPIKSPTFAGGLFS
ISKSYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKG
INVIARNQVRLAEVWMDGYKEIFYRRNLQAAQMAREKSFGDISERLQLRERLNCHNFSWF
LDNVYPEMFVPDLKPTFFGALKNLGVDHCLDVGENNNGGKPLILYTCHGLGGNQYFEYTT
QRDLRHNIAKQLCLHASAGTLGLRSCHFTGKNSQVPKDEEWEFTQDQLIRNSGSGTCLTS
KDKKPVMATCNPSDPHQHWLFI
Enzyme 13 Number of Residues 622
Enzyme 13 Molecular Weight 71137.8
Enzyme 13 Theoretical pI 8.07
Enzyme 13 GO Classification
Function
Process
Component
Enzyme 13 General Function Cell wall/membrane/envelope biogenesis
Enzyme 13 Specific Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. May participate in synthesis of oncofetal fibronectin. Has activity toward Muc1a, Muc2, EA2 and fibronectin peptides
Enzyme 13 Pathways
  • Protein modification
  • protein glycosylation
Enzyme 13 Reactions Not Available
Enzyme 13 Pfam Domain Function
Enzyme 13 Signals
  • None
Enzyme 13 Transmembrane Regions
  • 9-28
Enzyme 13 Essentiality Not Available
Enzyme 13 GenBank ID Protein 59857821 Link Image
Enzyme 13 UniProtKB/Swiss-Prot ID Q5EA41 Link Image
Enzyme 13 UniProtKB/Swiss-Prot Entry Name GALT6_BOVIN Link Image
Enzyme 13 PDB ID Not Available
Enzyme 13 Cellular Location Not Available
Enzyme 13 Gene Sequence >1869 bp
ATGAGGCTGCTCCGCAGACGCCACATGGCCGTGCGCCTGGTCATGGTGGGCAGCGCCTTC
GTGCTCTTTCTCTTCATCCTGCAGAGGGACGTAAGTGGCAGGGAGCAGGCCACAGAGAAG
CCATGGCTGAGGTCCTTGGTGAGCCAGAAGGACCACGTCTTGGACCTCATGCTGGGGGCC
GTGCACAACCTCAGGGACTCGATGCCCAAGTTCCAGATCAGGGCTCCAGAGCCCCAGCAG
ACACTGGCCTCCACCAACCAGTCCTGCCTCCCAGGTTTCTACACCCCAGCTGAGCTGAAG
CCATTCTGGGAACGGCCGCCACAGGACCCCAATGGCCCTGGGGCGGATGGGAAGGCGTTT
CAGAAGAAAGAGTGGACGCCCCAGGAGACCCAGGAAAAGGAAGAGGGCTATAAGAAGCAC
TGCTTCAATGCCTTTGCCAGTGACCGCATCTCCCTGCAGAGGGCCCTGGGGCCGGACACC
CGACCCCCTGAGTGTGTCGACCAGAAGTTCCGGCGCTGCCCCCCGCTGCCTGCCACCAGC
GTCATCATTGTGTTCCACAATGAGGCCTGGTCCACTCTGCTGCGGACGGTGTACAGCGTC
CTGCACACCACCCCTGCCATCCTGCTGAAGGAGATCATTCTGGTAGATGATGCCAGCACG
GACGAGTACTTGAAGGAGCCCCTGGAGCGGTACGTGAAGCAGCTGCAGGTGGTGCAGGTG
GTGCGGCAGCAGGAGAGGAAGGGGCTGATCACCGCCCGGCTGCTGGGGGCCAGCGTGGCC
CAGGCGGAGGTGCTCACCTTCCTGGATGCCCACTGTGAGTGCTTCCACGGCTGGCTAGAG
CCACTCCTGGCTCGCATCGCCGAGGACGAGACGGTGGTGGTGAGCCCAAACATCGTCACC
ATTGACCTGAACACTTTTGAGTTCTCCAAGCCTGTCCAGAGGGGCCGAGTCCAGAGTCGG
GGCAACTTTGACTGGAGCCTGACCTTCGGCTGGGAGGTTTTACCGGCACGAGAGAAGCAG
AGGCGCAAGGATGAGACCTACCCCATCAAATCCCCGACGTTTGCTGGTGGCCTCTTCTCC
ATCTCCAAGTCCTACTTTGAGCACATCGGTACCTATGATAACCAGATGGAGATCTGGGGA
GGGGAGAACGTGGAAATGTCCTTCCGGGTGTGGCAGTGCGGCGGCCAGCTAGAGATTATC
CCCTGCTCTGTGGTCGGACACGTGTTCCGTACCAAGAGCCCCCACACCTTCCCCAAGGGC
ATCAATGTCATTGCTCGCAACCAAGTGCGCCTGGCTGAGGTCTGGATGGATGGCTACAAG
GAGATTTTCTACAGGAGAAATCTGCAGGCAGCACAGATGGCCCGAGAGAAATCCTTTGGC
GACATTTCGGAACGACTGCAGCTGAGGGAGCGACTAAACTGTCACAACTTTTCCTGGTTC
CTGGACAACGTTTACCCGGAGATGTTTGTCCCTGACCTGAAGCCCACCTTCTTTGGAGCT
CTCAAGAACCTCGGCGTGGATCACTGTCTGGATGTGGGAGAGAACAACAACGGGGGAAAG
CCCCTCATCCTGTACACCTGCCATGGCCTCGGTGGCAACCAGTACTTTGAGTACACAACC
CAGAGAGACCTTCGCCACAACATCGCAAAGCAGCTGTGTCTACATGCCAGTGCTGGCACT
CTGGGCCTTAGGAGCTGTCACTTCACCGGCAAGAATAGCCAAGTGCCCAAGGATGAGGAA
TGGGAATTCACCCAGGATCAACTCATCAGGAACTCAGGATCTGGTACCTGCCTGACATCC
AAAGACAAAAAGCCAGTCATGGCCACCTGCAACCCCAGTGATCCCCACCAGCACTGGCTC
TTCATTTAG
Enzyme 13 GenBank Gene ID BT020728 Link Image
Enzyme 13 GeneCard ID GALNT6 Link Image
Enzyme 13 GenAtlas ID Not Available
Enzyme 13 HGNC ID Not Available
Enzyme 13 Chromosome Location Chromosome:1
Enzyme 13 Locus 12q13
Enzyme 13 SNPs SNPJam Report Link Image
Enzyme 13 General References
  1. [PubMed Link Image]
Enzyme 13 Metabolite References Not Available
Enzyme 14 [top]
Enzyme 14 ID 382
Enzyme 14 Name Polypeptide N-acetylgalactosaminyltransferase 1
Enzyme 14 Synonyms
  1. Protein-UDP acetylgalactosaminyltransferase 1
  2. UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1
  3. Polypeptide GalNAc transferase 1
  4. pp-GaNTase 1
  5. GalNAc-T1
  6. Polypeptide N-acetylgalactosaminyltransferase 1 soluble form
Enzyme 14 Gene Name GALNT1
Enzyme 14 Protein Sequence >Polypeptide N-acetylgalactosaminyltransferase 1
MRKFAYCKVVLATSLIWVLLDMFLLLYFSECNKCDEKKERGLPAGDVLEPVQKPHEGPGE
MGKPVVIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSV
VIVFHNEAWSTLLRTVHSVINRSPRHMLEEIVLVDDASERDFLKRPLESYVKKLKVPVHV
IRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRKTVVCPIIDV
ISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDR
DYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQ
IINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRLGLRHKLQCRPFSWYLENIYP
DSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDD
LCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATDEDSQVPSIRDC
SGSRSQQWLLRNVTLPEIF
Enzyme 14 Number of Residues 559
Enzyme 14 Molecular Weight 64191.5
Enzyme 14 Theoretical pI 7.77
Enzyme 14 GO Classification
Function
Process
Component
Enzyme 14 General Function Involved in calcium ion binding
Enzyme 14 Specific Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7
Enzyme 14 Pathways
  • Protein modification
  • protein glycosylation
Enzyme 14 Reactions Not Available
Enzyme 14 Pfam Domain Function
Enzyme 14 Signals
  • None
Enzyme 14 Transmembrane Regions
  • 9-28
Enzyme 14 Essentiality Not Available
Enzyme 14 GenBank ID Protein 289412 Link Image
Enzyme 14 UniProtKB/Swiss-Prot ID Q07537 Link Image
Enzyme 14 UniProtKB/Swiss-Prot Entry Name GALT1_BOVIN Link Image
Enzyme 14 PDB ID 1XHB Link Image
Enzyme 14 PDB File Show
Enzyme 14 3D Structure
Enzyme 14 Cellular Location Not Available
Enzyme 14 Gene Sequence >1680 bp
ATGAGAAAATTTGCATACTGCAAGGTGGTCCTAGCCACCTCCTTGATTTGGGTACTCTTG
GATATGTTCCTGCTGCTTTACTTCAGTGAATGCAACAAATGTGATGAAAAAAAAGAGAGA
GGACTTCCTGCTGGGGATGTTCTAGAGCCAGTACAAAAGCCTCATGAAGGTCCTGGAGAA
ATGGGGAAACCAGTCGTCATTCCTAAAGAGGATCAAGAAAAGATGAAAGAGATGTTTAAA
ATCAATCAGTTCAATTTAATGGCAAGTGAGATGATTGCACTCAACAGATCTCTACCAGAT
GTTAGATTAGAAGGGTGTAAAACAAAGGTGTATCCAGATAACCTTCCTACAACCAGTGTG
GTGATTGTTTTCCACAATGAGGCTTGGAGCACACTTCTGCGAACTGTCCATAGCGTCATT
AATCGCTCACCAAGGCACATGCTAGAAGAAATTGTTCTAGTAGATGATGCCAGTGAAAGA
GACTTTTTAAAAAGACCTCTAGAGAGTTACGTGAAAAAATTAAAAGTACCCGTTCACGTC
ATTCGAATGGAGCAGCGTTCTGGATTGATCAGAGCTAGGTTAAAAGGTGCTGCTGTGTCT
AAAGGCCAAGTGATCACCTTTTTAGACGCGCACTGTGAGTGCACAGTGGGGTGGCTGGAG
CCTCTCTTAGCCAGGATCAAACATGACAGGAAGACAGTGGTCTGTCCCATCATAGATGTG
ATCAGTGATGACACTTTCGAGTACATGGCAGGTTCTGACATGACCTATGGCGGGTTCAAC
TGGAAGCTCAACTTTCGCTGGTATCCTGTTCCCCAAAGAGAAATGGACAGAAGGAAAGGT
GATCGGACTCTTCCTGTGAGAACACCTACAATGGCAGGAGGCCTTTTTTCAATAGACAGA
GATTACTTTCAGGAAATTGGAACATATGATGCTGGAATGGATATTTGGGGAGGAGAAAAC
CTAGAAATTTCCTTTAGGATTTGGCAGTGTGGAGGAACTTTGGAGATTGTTACTTGCTCA
CATGTTGGACATGTGTTTCGGAAAGCTACACCCTACACGTTTCCAGGAGGCACGGGGCAG
ATTATCAATAAAAATAACAGACGACTTGCAGAAGTATGGATGGATGAATTCAAGAATTTC
TTCTATATAATTTCTCCAGGTGTTACAAAGGTAGATTATGGAGATATATCATCAAGACTT
GGTCTAAGGCACAAACTCCAATGCAGACCATTCTCTTGGTACCTAGAGAATATTTATCCT
GATTCTCAGATTCCTCGTCACTATTTCTCTTTGGGAGAGATACGAAATGTGGAAACAAAT
CAGTGTCTAGATAACATGGCTAGAAAAGAGAATGAAAAAGTTGGAATTTTTAACTGTCAT
GGTATGGGAGGTAATCAGGTTTTCTCTTACACTGCCAACAAAGAAATTAGAACAGATGAC
CTTTGCTTGGATGTCTCCAAACTTAATGGCCCAGTCACAATGCTCAAATGCCACCACCTA
AAAGGCAACCAGCTTTGGGAGTATGACCCGGTGAAGTTGACCCTGCAGCATGTGAACAGT
AACCAGTGCCTGGACAAAGCCACAGACGAGGACAGCCAGGTGCCCAGCATCAGAGACTGC
AGCGGAAGCCGATCCCAGCAGTGGCTTCTTCGGAACGTCACCCTTCCAGAAATATTCTGA
Enzyme 14 GenBank Gene ID L07780 Link Image
Enzyme 14 GeneCard ID GALNT1 Link Image
Enzyme 14 GenAtlas ID Not Available
Enzyme 14 HGNC ID Not Available
Enzyme 14 Chromosome Location Chromosome:1
Enzyme 14 Locus 18q12.1
Enzyme 14 SNPs SNPJam Report Link Image
Enzyme 14 General References
  1. [PubMed Link Image]
Enzyme 14 Metabolite References Not Available
Enzyme 15 [top]
Enzyme 15 ID 427
Enzyme 15 Name Fumarylacetoacetase
Enzyme 15 Synonyms
  1. FAA
  2. Fumarylacetoacetate hydrolase
  3. Beta-diketonase
Enzyme 15 Gene Name FAH
Enzyme 15 Protein Sequence >Fumarylacetoacetase
MSFVPVAEDSDFPIHNLPYGVFSTRGNPRPRIGVAIGDQILDLSVIKHLFTGPILSGHQD
VFNKPTLNSFMGLGQAAWKEARAFLQNLLSASQARLRDDVELRQRAFTSQASATMYLPAT
IGDYTDFYSSRHHATNVGVMFRGKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPLGQM
RPDDSKPPVYGACKLLDFELEMAFFVGPGNKLGEPIPISKAHEHIFGMVLMNDWSARDIQ
KWEYVPLGPFLGKSFGTTISPWVVPMDALMPFAVSNPEQDPKPLPYLCHDQPYTFDINLS
VALKGEGMSQAATICRSNFKYMYWTMLQQLTHHSVNGCNLQPGDLLASGTISGPEPESFG
CMLELSWKGTRAVELGNGQTRKFLLDGDEVIMTGHCQGDGYRIGFGQCAGKVLPALSFA
Enzyme 15 Number of Residues 419
Enzyme 15 Molecular Weight 46155.6
Enzyme 15 Theoretical pI 6.99
Enzyme 15 GO Classification
Function
Process
Component
Enzyme 15 General Function Secondary metabolites biosynthesis, transport and catabolism
Enzyme 15 Specific Function 4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate
Enzyme 15 Pathways
  • Amino-acid degradation
  • L-phenylalanine degradation
  • acetoacetate and fumarate from L-phenylalanine:step 6/6
Enzyme 15 Reactions Not Available
Enzyme 15 Pfam Domain Function
Enzyme 15 Signals
  • None
Enzyme 15 Transmembrane Regions
  • None
Enzyme 15 Essentiality Not Available
Enzyme 15 GenBank ID Protein 148745316 Link Image
Enzyme 15 UniProtKB/Swiss-Prot ID A5PKH3 Link Image
Enzyme 15 UniProtKB/Swiss-Prot Entry Name FAAA_BOVIN Link Image
Enzyme 15 PDB ID 1QQJ Link Image
Enzyme 15 PDB File Show
Enzyme 15 3D Structure
Enzyme 15 Cellular Location Not Available
Enzyme 15 Gene Sequence >1260 bp
ATGTCCTTCGTCCCGGTGGCCGAGGATTCTGACTTCCCCATCCACAACCTGCCCTACGGC
GTCTTCTCCACCCGAGGCAACCCAAGACCGAGGATTGGCGTGGCCATTGGGGACCAGATC
CTGGACCTCAGTGTCATCAAGCACCTCTTCACTGGGCCGATCCTCTCCGGACACCAGGAT
GTCTTCAATAAGCCAACTCTCAACAGCTTCATGGGCCTGGGTCAGGCTGCCTGGAAGGAG
GCTAGAGCATTCTTGCAGAACCTGCTGTCTGCCAGCCAAGCCAGGCTCAGAGATGACGTG
GAGCTTCGGCAGCGTGCCTTCACATCCCAGGCTTCCGCTACGATGTATCTTCCGGCCACC
ATAGGTGACTACACGGACTTCTATTCCTCTCGGCATCATGCCACCAATGTCGGGGTTATG
TTCAGGGGCAAGGAGAATGCACTGATGCCAAACTGGCTGCACCTGCCCGTGGGCTACCAC
GGGCGCGCTTCCTCCGTGGTGGTGTCTGGCACCCCGATCCGCAGGCCCCTGGGGCAGATG
CGACCCGACGACTCTAAGCCTCCCGTTTATGGTGCCTGCAAACTCCTGGACTTCGAGTTG
GAGATGGCTTTCTTTGTAGGCCCTGGGAACAAACTCGGAGAGCCAATCCCCATTTCCAAG
GCCCACGAGCACATTTTTGGAATGGTCCTTATGAACGACTGGAGTGCTCGAGACATCCAG
AAATGGGAGTACGTCCCACTTGGGCCGTTCCTTGGGAAGAGTTTTGGAACCACCATCTCT
CCGTGGGTGGTGCCCATGGATGCCCTCATGCCCTTTGCTGTGTCCAACCCGGAGCAGGAC
CCCAAGCCCCTGCCGTATCTCTGCCATGACCAGCCCTACACATTCGACATCAACCTCTCT
GTTGCCCTGAAAGGAGAAGGAATGAGCCAGGCAGCTACCATATGCAGGTCTAATTTTAAG
TACATGTACTGGACAATGCTGCAGCAGCTCACCCACCACTCTGTCAATGGCTGCAACCTG
CAGCCGGGCGACCTCTTGGCTTCTGGAACCATCAGCGGGCCGGAGCCAGAGAGCTTCGGC
TGCATGCTGGAGCTGTCGTGGAAGGGCACAAGGGCCGTAGAGCTGGGGAATGGCCAGACC
AGGAAGTTCCTGCTGGATGGGGATGAAGTCATCATGACAGGGCACTGCCAGGGGGATGGG
TACCGCATTGGCTTCGGCCAGTGTGCGGGAAAAGTGCTGCCTGCCCTGTCGTTCGCCTGA
Enzyme 15 GenBank Gene ID BC142487 Link Image
Enzyme 15 GeneCard ID FAH Link Image
Enzyme 15 GenAtlas ID Not Available
Enzyme 15 HGNC ID Not Available
Enzyme 15 Chromosome Location Chromosome:1
Enzyme 15 Locus 15q23-q25
Enzyme 15 SNPs SNPJam Report Link Image
Enzyme 15 General References Not Available
Enzyme 15 Metabolite References Not Available
Enzyme 16 [top]
Enzyme 16 ID 506
Enzyme 16 Name Fumarylacetoacetate hydrolase domain-containing protein 2
Enzyme 16 Synonyms Not Available
Enzyme 16 Gene Name FAHD2
Enzyme 16 Protein Sequence >Fumarylacetoacetate hydrolase domain-containing protein 2
MLGSSGRRLLTTVLQAQRWPFQPSRDMRLVQFQAPHLAGPHLGLESGNGGGVIDLNAFEP
TLPKTMVEFLEQGEATLSVVRRALATQLPVLPRSEVTFLAPVTRPDKVVCVGMNYADHCR
EQNVPVPKEPIIFSKFASAIVGPYDNIILPPESQEVDWEVELAVVIGKRGKYIKATDAMA
HVAGFTVAHDVSARDWQMGRNGKQWLLGKTFDTFCPLGPALVTKDSVADPHNLKICCRVN
GELMQSSNTNQMVFKTEELITWVSQFVTLYPGDIILTGTPPGVGVFRKPPVFLKKGDEVQ
CEIEELGVIINKVV
Enzyme 16 Number of Residues 314
Enzyme 16 Molecular Weight 34555.8
Enzyme 16 Theoretical pI 6.78
Enzyme 16 GO Classification
Function
Process
Component
Enzyme 16 General Function Secondary metabolites biosynthesis, transport and catabolism
Enzyme 16 Specific Function May have hydrolase activity
Enzyme 16 Pathways Not Available
Enzyme 16 Reactions Not Available
Enzyme 16 Pfam Domain Function
Enzyme 16 Signals
  • None
Enzyme 16 Transmembrane Regions
  • None
Enzyme 16 Essentiality Not Available
Enzyme 16 GenBank ID Protein 37780029 Link Image
Enzyme 16 UniProtKB/Swiss-Prot ID Q2KIB0 Link Image
Enzyme 16 UniProtKB/Swiss-Prot Entry Name FAHD2_BOVIN Link Image
Enzyme 16 PDB ID Not Available
Enzyme 16 Cellular Location Not Available
Enzyme 16 Gene Sequence >945 bp
ATGCTGGGGTCCAGTGGCAGGAGGTTGCTCACGACTGTGCTGCAGGCACAGAGGTGGCCC
TTTCAGCCCTCCAGAGACATGAGATTGGTGCAGTTCCAGGCACCCCACCTAGCGGGACCC
CACCTGGGCCTGGAGTCAGGGAATGGCGGGGGTGTCATCGACCTCAACGCCTTTGAGCCC
ACACTGCCCAAGACGATGGTGGAGTTCCTGGAGCAGGGAGAAGCCACTCTGTCAGTGGTG
AGAAGAGCACTGGCCACCCAGTTGCCAGTCCTCCCACGGTCAGAGGTGACGTTCCTGGCC
CCAGTCACTCGGCCAGACAAGGTGGTGTGCGTGGGCATGAACTATGCAGACCACTGCAGA
GAACAGAACGTGCCTGTGCCCAAGGAGCCCATCATCTTCAGCAAGTTCGCCAGCGCCATT
GTGGGGCCCTATGACAACATCATCCTTCCGCCTGAGAGCCAGAAGGTGGACTGGGAAGTG
GAGCTGGCCGTGGTCATCGGAAAGAGAGGCAAGTACATCAAGGCTACAGATGCCATGGCC
CATGTGGCTGGCTTCACTGTGGCACACGACGTGAGTGCTCGTGACTGGCAGATGGGACGC
AATGGAAAGCAGTGGTTGCTGGGGAAAACCTTTGACACCTTCTGCCCTCTGGGCCCTGCC
TTGGTGACCAAGGACAGCGTGGCAGACCCACACAACCTAAAGATCTGCTGCCGAGTAAAT
GGGGAAGTGATGCAGAGCAGCAATACCAACCAGATGGTGTTTAAGACAGAAGAGCTGATA
ACCTGGGTCTCCCAGTTCGTTACTCTTTACCCAGGGGACATCATCCTGACCGGGACGCCC
CCAGGTGTGGGTGTGTTCAGGAAGCCTCCTGTCTTCCTCAAGAAAGGCGATGAAGTCCAG
TGTGAGATTGAAGAACTGGGTGTCATCATCAACAAGGTGGTGTGA
Enzyme 16 GenBank Gene ID AY192436 Link Image
Enzyme 16 GeneCard ID FAHD2 Link Image
Enzyme 16 GenAtlas ID Not Available
Enzyme 16 HGNC ID Not Available
Enzyme 16 Chromosome Location Not Available
Enzyme 16 Locus Not Available
Enzyme 16 SNPs SNPJam Report Link Image
Enzyme 16 General References Not Available
Enzyme 16 Metabolite References Not Available
Enzyme 17 [top]
Enzyme 17 ID 519
Enzyme 17 Name Fumarylacetoacetate hydrolase domain-containing protein 1
Enzyme 17 Synonyms Not Available
Enzyme 17 Gene Name FAHD1
Enzyme 17 Protein Sequence >Fumarylacetoacetate hydrolase domain-containing protein 1
MAASRPLSRFWEWGKNIVCVGRNYADHVREMQSAAPSEPVLFLKPSTAYAPEGSPVLVPA
YTRNLHHELELAVVMGKRCRAVSEAAAMDYVAGYALCLDMTARDVQDECKKKGLPWTLAK
SFTASCPVSAFVPKEKIPDPHNLKLWLKVNGELRQEGETSSMIFSIPYIISYVSKIMTLE
EGDIILTGTPKGVGPVKENDEIQAGIHGVLSMKFKVERPEY
Enzyme 17 Number of Residues 221
Enzyme 17 Molecular Weight 24499.2
Enzyme 17 Theoretical pI 7.45
Enzyme 17 GO Classification
Function
Process
Component
Enzyme 17 General Function Secondary metabolites biosynthesis, transport and catabolism
Enzyme 17 Specific Function May have hydrolase activity
Enzyme 17 Pathways Not Available
Enzyme 17 Reactions Not Available
Enzyme 17 Pfam Domain Function
Enzyme 17 Signals
  • None
Enzyme 17 Transmembrane Regions
  • None
Enzyme 17 Essentiality Not Available
Enzyme 17 GenBank ID Protein 87578205 Link Image
Enzyme 17 UniProtKB/Swiss-Prot ID Q2HJ98 Link Image
Enzyme 17 UniProtKB/Swiss-Prot Entry Name FAHD1_BOVIN Link Image
Enzyme 17 PDB ID 1SAW Link Image
Enzyme 17 PDB File Show
Enzyme 17 3D Structure
Enzyme 17 Cellular Location Not Available
Enzyme 17 Gene Sequence >666 bp
ATGGCCGCCAGCAGGCCGCTGTCCCGCTTCTGGGAGTGGGGGAAGAACATCGTGTGCGTG
GGCCGGAACTACGCGGACCACGTCCGGGAGATGCAGAGCGCCGCGCCCAGCGAGCCGGTG
CTCTTCCTGAAGCCGTCCACCGCCTACGCCCCCGAGGGCTCGCCGGTGCTCGTGCCCGCC
TACACCCGCAACCTGCATCACGAGCTCGAGCTCGCCGTGGTGATGGGCAAGCGCTGCCGC
GCCGTCTCGGAGGCCGCGGCCATGGACTACGTGGCCGGCTATGCCCTGTGCCTGGACATG
ACCGCCAGGGACGTGCAAGACGAGTGCAAGAAGAAGGGGCTGCCCTGGACTCTGGCCAAG
AGTTTCACGGCCTCCTGCCCGGTCAGTGCCTTCGTGCCCAAAGAGAAGATCCCTGACCCT
CACAACCTGAAGCTCTGGCTCAAGGTCAACGGCGAACTCAGGCAGGAGGGTGAGACATCC
TCCATGATTTTTTCCATCCCCTACATCATCAGCTACGTTTCTAAGATCATGACCTTGGAA
GAAGGAGATATTATCTTGACCGGGACGCCAAAGGGAGTGGGACCCGTTAAAGAAAATGAT
GAGATCCAGGCCGGCATACATGGCGTCCTCAGTATGAAGTTTAAGGTGGAGAGGCCAGAA
TATTGA
Enzyme 17 GenBank Gene ID BC113240 Link Image
Enzyme 17 GeneCard ID FAHD1 Link Image
Enzyme 17 GenAtlas ID Not Available
Enzyme 17 HGNC ID Not Available
Enzyme 17 Chromosome Location Chromosome:1
Enzyme 17 Locus 16p13.3
Enzyme 17 SNPs SNPJam Report Link Image
Enzyme 17 General References Not Available
Enzyme 17 Metabolite References Not Available
Enzyme 18 [top]
Enzyme 18 ID 572
Enzyme 18 Name Glutamyl aminopeptidase
Enzyme 18 Synonyms
  1. EAP
  2. Aminopeptidase A
  3. APA
  4. CD249 antigen
Enzyme 18 Gene Name ENPEP
Enzyme 18 Protein Sequence >Glutamyl aminopeptidase
MILEERSSWEGSKRYCIKTKHVAIICAVVVAVGLIVGLSVGLTRSCDSTEGMTQGTTQGT
TQAPSHLPPVTSPPEDQGVCPASEDESGGWKDFRLPDFIKPVHYDLEVKPLMEQDTYTGS
VDISINVSSSTRYLWLHLRETRITRLPVLRRPSGEQVQVRQCFEYKKQEYVVVEAEEELE
PNTGEGPYHLILEFAGWLNGSLVGFYRTTYVEKGQTKSIAATDHEPTDARKSFPCFDEPN
KKATYTISIVHSKEYKALSNMPVEKEESVDDIWSRTTFQKSVPMSTYLVCFAVHQFDSVT
RISNRGIPLTIYVQPEQKHTAEYAANITKSVFDYFEDYFGMSYSLPKLDKIAIPDFGTGA
MENWGLITYRETNLLYDPDESASSNKQRVAAVIAHELVHQWFGNIVTMEWWDDLWLNEGF
ASFFEYLGVAYAEKDWQMRDQMILDDVLPVQEDDSLMSSHPIVVTVATPDEITSVFDGIS
YSKGASILRMLENWITREKFQIGCQNYLKKHKFENAKTSDFWAALEEASNLPVKEVMDTW
TNQMGYPVLNVDNMKNITQKRFLLDPRANASEPHSAFGYTWNIPIKWTEDDEQRITLYNR
SETGGITLESTLSGNAFLKINPDHIGFYRVNYEVSTWEWIATNLSVNHTDFSSADRASFI
DDAFALARAQLLNYKEALNLTKYLKEEKEYLPWHRVISAVTYIISMFEDDKELYPVIEKY
FRDQVKPIADSLGWNDVGDHLTKLLRASVLGLACKMGDSDALNNASQLFQEWLTGTVSLP
VNLRLLVYRYGMQNSGNETSWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLL
KDSNLIKTQDVFTVIQYISYNSYGKTMAWNWIQLNWEYLVNRYTLNNRNLGRIVTIAEPF
NTELQLWQIKSFFERYPEAGAGQKPREQVLETVKNNIEWLKQNRDTIRNWFLDLNG
Enzyme 18 Number of Residues 956
Enzyme 18 Molecular Weight 109800.1
Enzyme 18 Theoretical pI 4.92
Enzyme 18 GO Classification
Function
Process
Component
Enzyme 18 General Function Amino acid transport and metabolism
Enzyme 18 Specific Function Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells
Enzyme 18 Pathways Not Available
Enzyme 18 Reactions Not Available
Enzyme 18 Pfam Domain Function
Enzyme 18 Signals
  • None
Enzyme 18 Transmembrane Regions
  • 22-42
Enzyme 18 Essentiality Not Available
Enzyme 18 GenBank ID Protein 81674650 Link Image
Enzyme 18 UniProtKB/Swiss-Prot ID Q32LQ0 Link Image
Enzyme 18 UniProtKB/Swiss-Prot Entry Name AMPE_BOVIN Link Image
Enzyme 18 PDB ID Not Available
Enzyme 18 Cellular Location Not Available
Enzyme 18 Gene Sequence >2871 bp
ATGATCTTGGAGGAGAGATCATCTTGGGAAGGCTCTAAGAGATACTGCATTAAGACGAAA
CATGTGGCCATTATCTGCGCAGTGGTGGTGGCTGTCGGATTAATAGTAGGACTTTCTGTG
GGTCTGACCAGATCATGTGACTCTACAGAGGGCATGACCCAGGGCACGACCCAGGGCACG
ACCCAGGCTCCTTCCCACCTGCCTCCCGTTACCAGCCCTCCAGAGGACCAGGGGGTCTGC
CCTGCCAGTGAGGATGAAAGCGGAGGCTGGAAAGACTTCAGGCTGCCGGACTTCATCAAA
CCAGTGCACTACGACCTGGAGGTGAAGCCCCTGATGGAGCAGGACACGTACACGGGCAGC
GTGGACATCTCCATCAACGTGAGCTCATCCACCCGGTACCTGTGGCTACATCTCCGGGAG
ACGAGGATCACCAGGCTCCCGGTGCTGAGGAGGCCGTCTGGGGAGCAGGTTCAAGTCAGG
CAGTGCTTCGAATACAAGAAGCAGGAGTATGTGGTGGTGGAAGCAGAAGAAGAGCTTGAG
CCCAACACTGGCGAGGGTCCCTACCACCTGATCCTGGAGTTCGCCGGCTGGCTGAACGGC
TCGCTCGTGGGATTTTACAGAACGACATACGTGGAGAAAGGACAAACCAAGAGCATAGCA
GCCACTGATCATGAACCAACAGATGCCAGGAAATCCTTCCCTTGTTTTGATGAGCCCAAC
AAAAAGGCAACGTATACAATATCCATTGTCCACTCCAAAGAATATAAGGCGCTTTCGAAT
ATGCCAGTGGAGAAAGAAGAGTCAGTGGATGATATATGGAGTCGGACAACTTTCCAGAAG
TCTGTTCCCATGAGTACTTACCTGGTGTGCTTTGCAGTGCATCAGTTTGACTCTGTAACG
AGAATATCAAACAGGGGGATACCTCTCACTATATATGTCCAGCCAGAGCAAAAGCACACA
GCTGAATATGCTGCAAACATAACTAAAAGTGTGTTTGACTATTTTGAAGACTACTTTGGT
ATGAGTTATTCTCTTCCTAAATTAGATAAAATTGCTATTCCAGATTTCGGCACTGGGGCT
ATGGAGAACTGGGGACTCATCACTTACAGAGAAACAAACCTGCTTTATGACCCTGATGAA
TCTGCCTCATCAAACAAACAGAGGGTGGCTGCTGTGATAGCCCATGAGCTTGTGCATCAG
TGGTTTGGAAATATTGTGACCATGGAATGGTGGGACGACTTGTGGCTAAATGAAGGATTT
GCTTCCTTCTTTGAGTACCTGGGAGTAGCCTATGCAGAAAAAGACTGGCAAATGCGTGAT
CAGATGATACTTGATGATGTATTACCTGTGCAAGAGGATGATTCTTTGATGTCTTCACAC
CCAATAGTAGTCACTGTAGCAACTCCTGATGAAATAACATCTGTTTTTGATGGAATTTCC
TATAGTAAGGGAGCTTCCATTCTGAGAATGCTTGAAAACTGGATAACACGAGAGAAATTT
CAAATAGGATGTCAGAATTACTTGAAAAAACACAAATTTGAGAATGCCAAAACTTCAGAT
TTCTGGGCAGCACTTGAAGAGGCAAGTAATCTCCCAGTGAAAGAAGTAATGGACACCTGG
ACCAATCAGATGGGTTACCCTGTACTTAACGTGGACAATATGAAGAACATCACACAGAAA
CGCTTTCTATTGGACCCGAGAGCTAATGCTTCTGAGCCACATTCAGCTTTTGGTTACACA
TGGAATATTCCAATTAAATGGACTGAAGATGATGAACAAAGGATTACATTATACAATAGG
TCAGAAACAGGAGGAATCACTTTGGAATCTACTCTTAGTGGGAATGCTTTTCTCAAAATA
AACCCTGATCATATTGGCTTTTATCGTGTAAATTATGAAGTGTCAACTTGGGAATGGATA
GCTACGAATCTTTCCGTCAACCACACGGACTTTTCTTCTGCTGATCGTGCAAGTTTTATT
GATGATGCTTTTGCCTTGGCACGAGCTCAGCTTCTAAATTATAAGGAGGCTCTGAACTTG
ACCAAGTATCTCAAGGAAGAAAAGGAATATTTACCATGGCACAGAGTCATTTCAGCTGTA
ACCTATATTATTAGCATGTTTGAAGATGATAAAGAGCTATACCCTGTGATTGAGAAATAC
TTCCGAGATCAAGTGAAGCCCATTGCAGATTCTCTGGGATGGAATGATGTTGGAGACCAC
CTCACAAAATTACTCCGTGCGTCTGTATTAGGACTGGCGTGCAAGATGGGAGACAGCGAT
GCCTTGAACAACGCTTCCCAGTTATTTCAGGAGTGGCTAACTGGGACTGTAAGTCTTCCT
GTAAATCTCAGGCTTCTGGTATATCGGTATGGTATGCAGAACTCTGGCAATGAGACTTCA
TGGAATTACACTCTCGAGCAATACCAGAAAACTTCATTAGCTCAAGAAAAAGAAAAGCTA
CTGTATGGATTAGCATCAGTGAAGAATGTTACTCTTTTGTCAAGGTATTTGGATTTACTC
AAGGACTCAAACCTTATTAAAACGCAGGATGTGTTTACAGTCATTCAGTACATCTCATAC
AACAGCTATGGGAAGACTATGGCCTGGAATTGGATACAACTCAACTGGGAATATCTAGTC
AACAGGTATACACTCAATAACAGAAACCTTGGCCGGATTGTCACTATAGCAGAGCCATTC
AACACTGAACTACAACTCTGGCAGATCAAGAGCTTTTTCGAAAGATATCCTGAAGCTGGA
GCGGGACAAAAACCTAGGGAGCAAGTACTGGAAACAGTGAAAAACAATATCGAGTGGCTA
AAACAAAACAGGGACACCATAAGAAACTGGTTTCTTGATTTGAATGGTTAA
Enzyme 18 GenBank Gene ID BC109476 Link Image
Enzyme 18 GeneCard ID ENPEP Link Image
Enzyme 18 GenAtlas ID Not Available
Enzyme 18 HGNC ID Not Available
Enzyme 18 Chromosome Location Chromosome:4
Enzyme 18 Locus 4q25
Enzyme 18 SNPs SNPJam Report Link Image
Enzyme 18 General References Not Available
Enzyme 18 Metabolite References Not Available
Enzyme 19 [top]
Enzyme 19 ID 644
Enzyme 19 Name UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
Enzyme 19 Synonyms Not Available
Enzyme 19 Gene Name GALNT6
Enzyme 19 Protein Sequence >UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
MRLLRRRHMAVRLVMVGSAFVLFLFILQRDVSGREQATEKPWLRSLVSQKDHVLDLMLGA
VHNLRDSMPKFQIRAPEPQQTLASTNQSCLPGFYTPAELKPFWERPPQDPNGPGADGKAF
QKKEWTPQETQEKEEGYKKHCFNAFASDRISLQRALGPDTRPPECVDQKFRRCPPLPATS
VIIVFHNEAWSTLLRTVYSVLHTTPAILLKEIILVDDASTDEYLKEPLERYVKQLQVVQV
VRQQERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDETVVVSPNIVT
IDLNTFEFSKPVQRGRIQSRGNFDWSLTFGWEVLPAREKQRRKDETYPIKSPTFAGGLFS
ISKSYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKG
INVIARNQVRLAEVWMDGYKEIFYRRNLQAAQMAREKSFGDISERLQLRERLNCHNFSWF
LDNVYPEMFVPDLKPTFFGALKNLGVDHCLDVGENNNGGKPLILYTCHGLGGNQYFEYTT
QRDLRHNIAKQLCLHASAGTLGLRSCHFTGKNSQVPKDEEWEFTQDQLIRNSGSGTCLTS
KDKKPVMATCNPSDPHQHWLFI
Enzyme 19 Number of Residues 622
Enzyme 19 Molecular Weight 71151.9
Enzyme 19 Theoretical pI 8.07
Enzyme 19 GO Classification
Function
Process
Component
Enzyme 19 General Function Cell wall/membrane/envelope biogenesis
Enzyme 19 Specific Function Not Available
Enzyme 19 Pathways
  • Protein modification
  • protein glycosylation
Enzyme 19 Reactions Not Available
Enzyme 19 Pfam Domain Function
Enzyme 19 Signals
  • None
Enzyme 19 Transmembrane Regions
  • None
Enzyme 19 Essentiality Not Available
Enzyme 19 GenBank ID Protein 148878418 Link Image
Enzyme 19 UniProtKB/Swiss-Prot ID A6H6Z5 Link Image
Enzyme 19 UniProtKB/Swiss-Prot Entry Name A6H6Z5_BOVIN Link Image
Enzyme 19 PDB ID Not Available
Enzyme 19 Cellular Location Not Available
Enzyme 19 Gene Sequence >1869 bp
ATGAGGCTGCTCCGCAGACGCCACATGGCCGTGCGCCTGGTCATGGTGGGCAGCGCCTTC
GTGCTCTTTCTCTTCATCCTGCAGAGGGACGTAAGTGGCAGGGAGCAGGCCACAGAGAAG
CCATGGCTGAGGTCCTTGGTGAGCCAGAAGGACCACGTCTTGGACCTCATGCTGGGGGCC
GTGCACAACCTCAGGGACTCGATGCCCAAGTTCCAGATCAGGGCTCCAGAGCCCCAGCAG
ACACTGGCCTCCACCAACCAGTCCTGCCTCCCAGGTTTCTACACCCCAGCTGAGCTGAAG
CCATTCTGGGAACGGCCGCCACAGGACCCCAATGGCCCTGGGGCGGATGGGAAGGCGTTT
CAGAAGAAAGAGTGGACGCCCCAGGAGACCCAGGAAAAGGAAGAGGGCTATAAGAAGCAC
TGCTTCAATGCCTTTGCCAGTGACCGCATCTCCCTGCAGAGGGCCCTGGGGCCGGACACC
CGACCCCCTGAGTGTGTCGACCAGAAGTTCCGGCGCTGCCCCCCGCTGCCTGCCACCAGC
GTCATCATTGTGTTCCACAATGAGGCCTGGTCCACTCTGCTGCGGACGGTGTACAGCGTC
CTGCACACCACCCCTGCCATCCTGCTGAAGGAGATCATTCTGGTAGATGATGCCAGCACG
GACGAGTACTTGAAGGAGCCCCTGGAGCGGTACGTGAAGCAGCTGCAGGTGGTGCAGGTG
GTGCGGCAGCAGGAGAGGAAGGGGCTGATCACCGCCCGGCTGCTGGGGGCCAGCGTGGCC
CAGGCGGAGGTGCTCACCTTCCTGGATGCCCACTGTGAGTGCTTCCACGGCTGGCTAGAG
CCACTCCTGGCTCGCATCGCCGAGGACGAGACGGTGGTGGTGAGCCCAAACATCGTCACC
ATTGACCTGAACACTTTTGAGTTCTCCAAGCCTGTCCAGAGGGGCCGAATCCAGAGTCGG
GGCAACTTTGACTGGAGCCTGACCTTCGGCTGGGAGGTTTTACCGGCACGAGAGAAGCAG
AGGCGCAAGGATGAGACCTACCCCATCAAATCCCCGACGTTTGCTGGTGGCCTCTTCTCC
ATCTCCAAGTCCTACTTTGAGCACATCGGTACCTATGATAACCAGATGGAGATCTGGGGA
GGGGAGAACGTGGAAATGTCCTTCCGGGTGTGGCAGTGCGGCGGCCAGCTAGAGATTATC
CCCTGCTCTGTGGTCGGACACGTGTTCCGTACCAAGAGCCCCCACACCTTCCCCAAGGGC
ATCAATGTCATTGCTCGCAACCAAGTGCGCCTGGCTGAGGTCTGGATGGATGGCTACAAG
GAGATTTTCTACAGGAGAAATCTGCAGGCAGCACAGATGGCCCGAGAGAAATCCTTTGGC
GACATTTCGGAACGACTGCAGCTGAGGGAGCGACTAAACTGTCACAACTTTTCCTGGTTC
CTGGACAACGTTTACCCGGAGATGTTTGTCCCTGACCTGAAGCCCACCTTCTTTGGAGCT
CTCAAGAACCTCGGCGTGGATCACTGTCTGGATGTGGGAGAGAACAACAACGGGGGAAAG
CCCCTCATCCTGTACACCTGCCATGGCCTCGGTGGCAACCAGTACTTTGAGTACACAACC
CAGAGAGACCTTCGCCACAACATCGCAAAGCAGCTGTGTCTACATGCCAGTGCTGGCACT
CTGGGCCTTAGGAGCTGTCACTTCACCGGCAAGAATAGCCAAGTGCCCAAGGATGAGGAA
TGGGAATTCACCCAGGATCAACTCATCAGGAACTCAGGATCTGGTACCTGCCTGACATCC
AAAGACAAAAAGCCGGTCATGGCCACCTGCAACCCCAGTGATCCCCACCAGCACTGGCTC
TTCATTTAG
Enzyme 19 GenBank Gene ID BC146055 Link Image
Enzyme 19 GeneCard ID GALNT6 Link Image
Enzyme 19 GenAtlas ID Not Available
Enzyme 19 HGNC ID Not Available
Enzyme 19 Chromosome Location Chromosome:1
Enzyme 19 Locus 12q13
Enzyme 19 SNPs SNPJam Report Link Image
Enzyme 19 General References Not Available
Enzyme 19 Metabolite References Not Available
Enzyme 20 [top]
Enzyme 20 ID 854
Enzyme 20 Name Coagulation factor XIII A chain
Enzyme 20 Synonyms
  1. Coagulation factor XIIIa
  2. Protein-glutamine gamma-glutamyltransferase A chain
  3. Transglutaminase A chain
  4. Fragment
Enzyme 20 Gene Name F13A1
Enzyme 20 Protein Sequence >Coagulation factor XIII A chain
MSESSGTAFGGRRAIPPNTSNAAENDPPTVELQGLVPRGFNPQDYLNVTNVHLFKERWDS
NKVDHHTDKYSNDKLIVRRGQSFYIQIDFNRPYDPTRDLFRVEYVIGLYPQENKGTYIPV
PLVSELQSGKWGAKVVMREDRSVRLSVQSSADCIVGKFRMYVAVWTPYGVIRTSRNPETD
TYILFNPWCEEDAVYLEN
Enzyme 20 Number of Residues 198
Enzyme 20 Molecular Weight 22744.4
Enzyme 20 Theoretical pI 6.27
Enzyme 20 GO Classification
Function
Process
Component
Enzyme 20 General Function Involved in acyltransferase activity
Enzyme 20 Specific Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin
Enzyme 20 Pathways Not Available
Enzyme 20 Reactions Not Available
Enzyme 20 Pfam Domain Function
Enzyme 20 Signals
  • None
Enzyme 20 Transmembrane Regions
  • None
Enzyme 20 Essentiality Not Available
Enzyme 20 GenBank ID Protein 95767504 Link Image
Enzyme 20 UniProtKB/Swiss-Prot ID P12260 Link Image
Enzyme 20 UniProtKB/Swiss-Prot Entry Name F13A_BOVIN Link Image
Enzyme 20 PDB ID Not Available
Enzyme 20 Cellular Location Not Available
Enzyme 20 Gene Sequence Not Available
Enzyme 20 GenBank Gene ID BT025350 Link Image
Enzyme 20 GeneCard ID F13A1 Link Image
Enzyme 20 GenAtlas ID Not Available
Enzyme 20 HGNC ID Not Available
Enzyme 20 Chromosome Location Chromosome:6
Enzyme 20 Locus 6p25.3-p24.3
Enzyme 20 SNPs SNPJam Report Link Image
Enzyme 20 General References
  1. [PubMed Link Image]
Enzyme 20 Metabolite References Not Available
Enzyme 21 [top]
Enzyme 21 ID 1046
Enzyme 21 Name Matrix metallopeptidase 2 (Gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
Enzyme 21 Synonyms Not Available
Enzyme 21 Gene Name MMP2
Enzyme 21 Protein Sequence >Matrix metallopeptidase 2 (Gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
MTEARVSRGALAALLRALCVLGCLLGRAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYG
CPKESCNLFVLKDTLKKMQKFFGLPQTGELDQSTIETMRKPRCGNPDVANYNFFPRKPKW
DKNQITYRIIGYTPDLDPQTVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHG
DGYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFRF
NGKEYTSCTDTGRSDGFLWCSTTYNFDKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQG
TSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVLPFTFLGNK
HESCTSAGRSDGKLWCATTSNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGA
LMAPIYTYTKNFRLSHDDIQGIQELYGASPDIDTGTGPTPTLGPVTPELCKQDIVFDGIS
QIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEDPQEEKAVFFAGNE
YWVYSASTLERGYPKPLTSLGLPPGVQKVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMD
PGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLG
C
Enzyme 21 Number of Residues 661
Enzyme 21 Molecular Weight 73833.5
Enzyme 21 Theoretical pI 5.44
Enzyme 21 GO Classification
Function
Process
Component
Enzyme 21 General Function Involved in calcium ion binding
Enzyme 21 Specific Function Not Available
Enzyme 21 Pathways Not Available
Enzyme 21 Reactions Not Available
Enzyme 21 Pfam Domain Function
Enzyme 21 Signals
  • None
Enzyme 21 Transmembrane Regions
  • None
Enzyme 21 Essentiality Not Available
Enzyme 21 GenBank ID Protein 151556868 Link Image
Enzyme 21 UniProtKB/Swiss-Prot ID A6QPN5 Link Image
Enzyme 21 UniProtKB/Swiss-Prot Entry Name A6QPN5_BOVIN Link Image
Enzyme 21 PDB ID 1GXD Link Image
Enzyme 21 PDB File Show
Enzyme 21 3D Structure
Enzyme 21 Cellular Location Not Available
Enzyme 21 Gene Sequence >1986 bp
ATGACCGAGGCGCGAGTGTCCCGGGGCGCGCTGGCCGCCCTTCTGCGGGCGCTCTGCGTC
CTGGGCTGCCTGTTGGGCCGTGCCGCCGCCGCGCCGTCGCCCATCATCAAATTTCCCGGC
GATGTCGCCCCCAAAACGGACAAAGAGTTGGCTGTGCAATACCTAAACACCTTCTACGGC
TGCCCCAAGGAGAGCTGTAACTTGTTTGTGCTGAAGGACACCCTGAAGAAGATGCAGAAG
TTCTTCGGGTTACCCCAGACAGGTGAACTGGACCAGAGCACCATTGAGACCATGCGGAAG
CCGCGCTGTGGCAACCCCGACGTGGCCAACTACAACTTCTTCCCCCGAAAGCCCAAGTGG
GACAAGAACCAGATCACATACAGGATCATTGGCTACACACCTGATCTGGACCCCCAGACA
GTGGATGATGCCTTCGCTCGTGCCTTCCAAGTCTGGAGCGATGTGACTCCGCTACGGTTT
TCTCGGATCCATGATGGAGAGGCTGACATCATGATCAACTTTGGCCGCTGGGAGCATGGA
GATGGGTACCCTTTTGATGGCAAAGACGGGCTCCTGGCTCATGCCTTCGCCCCGGGCCCT
GGAGTTGGGGGAGATTCCCACTTTGATGACGATGAGCTGTGGACCCTGGGAGAAGGACAA
GTGGTCCGTGTGAAGTACGGGAATGCTGACGGGGAATATTGCAAGTTCCCCTTCCGGTTC
AACGGCAAGGAGTACACCAGCTGCACAGACACAGGCCGCAGCGATGGCTTCCTCTGGTGT
TCCACCACATACAACTTTGACAAGGACGGCAAGTATGGCTTCTGCCCCCATGAAGCCCTG
TTCACCATGGGCGGCAATGCCGACGGACAGCCCTGCAAGTTCCCGTTCCGCTTCCAGGGC
ACGTCTTACGACAGCTGCACCACGGAGGGCCGCACGGACGGCTACCGCTGGTGTGGCACC
ACCGAGGACTACGACCGCGACAAGAAGTACGGCTTCTGCCCGGAGACCGCCATGTCCACT
GTGGGCGGGAACTCGGAAGGTGCCCCATGTGTCCTCCCCTTCACCTTCCTGGGCAACAAG
CACGAGAGCTGCACCAGCGCTGGCCGCAGTGATGGGAAGTTGTGGTGTGCGACCACCTCC
AACTACGATGATGACCGCAAGTGGGGCTTCTGCCCCGACCAAGGGTACAGCCTGTTCCTG
GTGGCAGCCCATGAGTTTGGCCATGCAATGGGGCTGGAGCACTCACAGGACCCTGGAGCC
CTGATGGCGCCCATTTATACCTATACTAAGAACTTCCGCCTGTCCCATGATGACATCCAG
GGCATCCAAGAACTCTATGGGGCCTCCCCTGACATTGATACTGGCACCGGCCCCACCCCA
ACCCTGGGCCCCGTCACTCCTGAGCTCTGCAAACAGGACATCGTCTTCGACGGCATCTCT
CAGATCCGTGGGGAGATCTTCTTCTTCAAGGACCGATTCATCTGGCGAACAGTGACACCA
CGTGACAAGCCCACAGGGCCCCTGCTGGTAGCCACATTCTGGCCTGAGCTGCCGGAAAAG
ATCGATGCTGTGTACGAAGACCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAACGAA
TACTGGGTCTATTCAGCCAGTACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTG
GGGCTCCCCCCTGGTGTCCAGAAGGTGGATGCTGCCTTTAACTGGAGCAAGAACAAGAAG
ACGTACATCTTCGCCGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGAT
CCTGGCTTCCCCAAGCTCATCGCCGATGCCTGGAACGCCATCCCTGATAACCTGGATGCT
GTGGTGGACCTGCAGGGCGGGGGTCACAGCTACTTCTTCAAGGGCGCCTATTACCTGAAG
TTGGAGAACCAAAGTCTGAAGAGCGTGAAGTTCGGAAGCATCAAATCCGATTGGCTGGGC
TGCTGA
Enzyme 21 GenBank Gene ID BC149404 Link Image
Enzyme 21 GeneCard ID MMP2 Link Image
Enzyme 21 GenAtlas ID Not Available
Enzyme 21 HGNC ID Not Available
Enzyme 21 Chromosome Location Chromosome:1
Enzyme 21 Locus 16q13-q21
Enzyme 21 SNPs SNPJam Report Link Image
Enzyme 21 General References Not Available
Enzyme 21 Metabolite References Not Available
Enzyme 22 [top]
Enzyme 22 ID 1064
Enzyme 22 Name Diacylglycerol kinase alpha
Enzyme 22 Synonyms
  1. DAG kinase alpha
  2. Diglyceride kinase alpha
  3. DGK-alpha
Enzyme 22 Gene Name DGKA
Enzyme 22 Protein Sequence >Diacylglycerol kinase alpha
MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAEYLQGDAIGYEGFQQFLKIY
LEVDNVPDHLSQALFQSFQTGYYIEDTVREDVVCLSDVSCYFSLLEGGRPEDKLEFTFKL
YDTDRNGILDSSEVDRIIIQMMRMAEYLDWDVSELRPILQEMMKEIDYDGSGSVSLAEWL
RAGATTVPLLVLLGLEMTLKDNGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKYI
VHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLVGLHCV
WCHLEIHDDCLPAMGHECDCGLLRDHILPPSSIYPSVLASGQERKTSKISQKTMDDLSLS
TSEALRIDPVSNTHPLLVFVNPKSGGKQGERVLWKFQYLLNPRQVFNLLKDGPEPGLRFF
RDVPDYRILVCGGDGTVGWILESIDKANLPFVPPVAVLPLGTGNDLARCLRWGGGYEGQN
LGKILKDLETSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMR
EKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVLN
IPSTHGGSNLWGDTKRPHGDIHGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLEG
AIEIGQIYTKLKNAGHRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHRNQMPMLV
GPPPRSSNFFGFLC
Enzyme 22 Number of Residues 734
Enzyme 22 Molecular Weight 82671.3
Enzyme 22 Theoretical pI 6.27
Enzyme 22 GO Classification
Function
Process
Component
Enzyme 22 General Function Involved in calcium ion binding
Enzyme 22 Specific Function Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity
Enzyme 22 Pathways Not Available
Enzyme 22 Reactions Not Available
Enzyme 22 Pfam Domain Function
Enzyme 22 Signals
  • None
Enzyme 22 Transmembrane Regions
  • None
Enzyme 22 Essentiality Not Available
Enzyme 22 GenBank ID Protein 117306586 Link Image
Enzyme 22 UniProtKB/Swiss-Prot ID A0JN54 Link Image
Enzyme 22 UniProtKB/Swiss-Prot Entry Name DGKA_BOVIN Link Image
Enzyme 22 PDB ID Not Available
Enzyme 22 Cellular Location Not Available
Enzyme 22 Gene Sequence >2205 bp
ATGGCCAAGGAGAGGGGCCTAATAAGCCCCAGTGATTTTGCCCAGCTGCAAAAATACATG
GAATACTCCACCAAAAAGGTCAGTGATGTTCTGAAGCTCTTTGAGGATGGTGAAATGGCT
GAATATCTCCAAGGAGATGCCATTGGATACGAGGGGTTCCAGCAATTCCTGAAAATCTAC
CTGGAGGTGGATAATGTTCCAGATCACCTAAGCCAGGCACTGTTTCAGTCCTTCCAGACT
GGCTACTACATAGAAGACACTGTAAGAGAAGATGTGGTGTGTCTCAGTGATGTCTCCTGC
TACTTTTCTCTTCTGGAGGGTGGCCGGCCAGAAGACAAGCTAGAATTCACCTTCAAGCTG
TACGACACGGACAGAAATGGGATCCTGGACAGCTCAGAAGTGGACAGGATCATCATACAG
ATGATGCGAATGGCTGAATACCTGGATTGGGATGTGTCTGAGCTGAGGCCGATTCTTCAA
GAGATGATGAAAGAGATTGACTATGATGGCAGTGGCTCTGTGTCCCTGGCTGAGTGGCTC
CGGGCTGGGGCCACCACCGTGCCACTGCTCGTGCTGCTGGGCCTGGAGATGACCCTGAAG
GACAATGGGCAGCACATGTGGAGACCCAAGAGATTCCCCCGACCAGTCTACTGCAACCTG
TGCGAGTCGAGCATTGGTCTTGGCAAACAGGGGCTGAGCTGTAACCTCTGTAAATACATC
GTTCACGACCAATGTGCCATGAAGGCCCTGCCCTGTGAAGTCAGCACCTATGCCAAGTCT
CGGAAGGACATTGGTGTCCAATCACACGTGTGGGTGCGAGGAGGCTGTGAATCTGGACGG
TGTGACCGCTGTCAGAAAAAGATCCGGATCTACCACAGTCTGGTTGGGCTGCATTGTGTG
TGGTGCCACCTAGAGATCCATGATGACTGCCTTCCAGCCATGGGCCATGAGTGTGACTGT
GGGCTGCTCCGAGATCACATCCTGCCTCCGTCTTCCATCTATCCCAGCGTCCTGGCCTCT
GGACAGGAGCGTAAAACTAGCAAAATAAGCCAGAAGACCATGGATGATTTAAGTTTGAGC
ACTTCTGAGGCTCTGCGGATTGATCCTGTTTCTAACACCCACCCACTTCTGGTCTTTGTG
AACCCCAAGAGTGGCGGGAAGCAAGGCGAGAGGGTGCTTTGGAAATTCCAGTATCTGCTG
AACCCTCGACAGGTGTTCAACCTCCTAAAGGATGGTCCTGAGCCAGGACTCAGATTCTTC
AGAGATGTTCCTGATTACAGGATTTTGGTGTGCGGCGGAGATGGCACAGTAGGCTGGATT
CTAGAGTCCATTGACAAAGCCAACTTGCCTTTTGTGCCTCCTGTCGCTGTGTTGCCCCTG
GGCACTGGAAATGATCTGGCTCGTTGCCTAAGATGGGGAGGAGGGTATGAGGGACAGAAT
CTGGGGAAGATCCTCAAGGATTTAGAGACAAGTAAGGTGGTACATATGGATCGATGGTCT
GTGGAGGTGATACCCCAACAAACTGAAGAAAAGAGTGACCCAGTCCCCTTTCAAATCATC
AATAACTACTTCTCCATCGGTGTGGATGCCTCTATTGCTCACCGATTCCACATTATGCGA
GAGAAATATCCTGAGAAGTTCAACAGCAGAATGAAGAACAAGCTATGGTACTTCGAATTT
GCCACTTCTGAATCCATCTTCTCAACGTGCAAAAAGCTGGAGGAATCTTTGACAGTTGAG
ATCTGTGGGAAACCACTGGATCTGAGCAACCTGTCCCTAGAAGGCATTGCAGTGCTGAAC
ATCCCAAGCACACATGGTGGCTCCAATCTCTGGGGTGACACCAAGAGACCACATGGCGAT
ATCCATGGGATCAACCAGGCCTTAGGTGCTACTGCCAAAGTCATCACCGACCCTGATATC
CTGAAGACCTGTGTACCAGACCTAAGTGACAAGCGGCTGGAAGTAGTGGGGCTGGAGGGT
GCAATTGAGATAGGCCAGATCTATACCAAGCTCAAGAATGCTGGACATCGGCTGGCCAAG
TGCTCTGAGATCACCTTCCACACCACAAAAACCCTCCCCATGCAAATTGACGGAGAACCC
TGGATGCAGACACCTTGTACAATCAAGATCACCCACAGGAACCAGATGCCTATGCTCGTG
GGCCCACCCCCTCGCTCCTCCAATTTTTTTGGCTTCTTGTGCTAA
Enzyme 22 GenBank Gene ID BC126521 Link Image
Enzyme 22 GeneCard ID DGKA Link Image
Enzyme 22 GenAtlas ID Not Available
Enzyme 22 HGNC ID Not Available
Enzyme 22 Chromosome Location Chromosome:1
Enzyme 22 Locus 12q13.3
Enzyme 22 SNPs SNPJam Report Link Image
Enzyme 22 General References Not Available
Enzyme 22 Metabolite References Not Available
Enzyme 23 [top]
Enzyme 23 ID 1161
Enzyme 23 Name Protein kinase C beta type
Enzyme 23 Synonyms
  1. PKC-beta
  2. PKC-B
Enzyme 23 Gene Name PRKCB
Enzyme 23 Protein Sequence >Protein kinase C beta type
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE
LRQKFERAKIGPGPKTPEEKTTNTISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLITKHPGKRLGCGPEGERDIKEHAFF
RYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFS
FVNSEFLKPEVKS
Enzyme 23 Number of Residues 673
Enzyme 23 Molecular Weight 76914.5
Enzyme 23 Theoretical pI 7.02
Enzyme 23 GO Classification
Function
Process
Component
Enzyme 23 General Function Involved in ATP binding
Enzyme 23 Specific Function This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May be considered as a novel component of the NF-kappa-B signaling axis responsible for the survival and activation of B-cells after BCR cross-linking
Enzyme 23 Pathways Not Available
Enzyme 23 Reactions Not Available
Enzyme 23 Pfam Domain Function
Enzyme 23 Signals
  • None
Enzyme 23 Transmembrane Regions
  • None
Enzyme 23 Essentiality Not Available
Enzyme 23 GenBank ID Protein 163524 Link Image
Enzyme 23 UniProtKB/Swiss-Prot ID P05126 Link Image
Enzyme 23 UniProtKB/Swiss-Prot Entry Name KPCB_BOVIN Link Image
Enzyme 23 PDB ID Not Available
Enzyme 23 Cellular Location Not Available
Enzyme 23 Gene Sequence >2022 bp
GCTCCGGCTCCCCGCGCGCAAGATGGCTGACCCGGCCGCGGGGCCGCCGCCGAGCGAGGG
AGAGGAGAGCACCGTGCGCTTCGCCCGCAAAGGCGCCCTCCGGCAGAAGAACGTGCACGA
GGTGAAGAACCACAAATTCACCGCCCGCTTCTTCAAGCAGCCCACCTTCTGCAGCCACTG
CACCGACTTCATCTGGGGCTTCGGGAAGCAAGGATTTCAGTGCCAAGTCTGCTGTTTTGT
CGTGCACAAGCGGTGCCATGAATTTGTCACCTTCTCCTGCCCGGGCGCTGACAAGGGCCC
AGCCTCTGACGACCCCCGGAGCAAACACAAGTTCAAGATCCACACATACTCCAGCCCCAC
GTTTTGTGACCACTGTGGGTCATTGCTCTATGGACTTATCCACCAGGGGATGAAATGTGA
CACCTGCATGATGAACGTCCACAAGCGCTGCGTGATGAACGTCCCCAGCCTCTGCGGCAC
GGACCACACGGAGCGCCGCGGCCGCATCTACATCCAAGCCCACATCGAGAGGGAGGTCCT
CATTGTTGTCGTAAGAGATGCTAAAAACCTTGTACCTATGGATCCTAATGGCTTGTCAGA
TCCTTACGTGAAACTGAAACTGATTCCTGATCCCAAGAGTGAGAGCAAGCAGAAGACCAA
GACCATCAAGTGCTCCCTCAACCCCGAGTGGAACGAAACATTTAGATTCCAGCTGAAAGA
ATCGGACAAAGACAGGAGACTGTCTGTAGAGATTTGGGATTGGGATCTGACCAGCAGAAA
TGACTTCATGGGATCTTTGTCGTTTGGGATTTCTGAACTGCAGAAAGCTGGTGTTGATGG
CTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAACGTGCCCGTGCCACCGGA
AGGCAGTGAGGGCAACGAGGAACTGCGACAGAAATTCGAGAGAGCCAAGATCGGTCCTGG
GCCCAAGACTCCTGAAGAAAAGACGACCAACACCATCTCCAAATTTGACAACAACGGCAA
CAGGGACCGGATGAAATTGACCGATTTTAACTTCCTGATGGTGCTGGGAAAAGGCAGCTT
TGGCAAGGTCATGCTCTCAGAGCGAAAAGGCACAGATGAGCTGTATGCTGTGAAGATCCT
GAAAAAGGACGTGGTCATCCAAGATGATGACGTGGAATGCACGATGGTGGAGAAGCGGGT
GCTGGCCCTGCCCGGGAAGCCGCCCTTCCTGACCCAGCTGCATTCCTGCTTCCAGACCAT
GGATCGCCTGTACTTTGTGATGGAGTATGTGAATGGTGGTGACCTCATGTACCACATCCA
GCAAGTGGGCCGGTTCAAGGAGCCTCACGCCGTATTTTACGCTGCAGAAATTGCCATCGG
TCTGTTCTTCTTGCAGAGCAAGGGCATCATTTACCGTGACCTGAAACTTGACAATGTGAT
GCTGGATTCCGAGGGCCACATCAAGATCGCTGATTTTGGCATGTGTAAGGAGAACATCTG
GGATGGGGTGACGACTAAGACCTTCTGCGGCACCCCAGACTACATCGCCCCCGAGATAAT
TGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGCGTCCTGCTGTATGA
GATGTTGGCTGGGCAGGCACCGTTTGAAGGGGAGGACGAGGATGAACTCTTCCAGTCCAT
CATGGAACACAACGTGGCTTATCCGAAGTCCATGTCCAAGGAAGCTGTGGCCATCTGCAA
AGGGCTGATCACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGTGAACGTGA
CATCAAAGAGCATGCATTTTTCCGGTATATTGACTGGGAGAAACTTGAACGCAAAGAGAT
TCAGCCCCCGTATAAGCCGAAAGCCTGTGGGCGAAATGCTGAAAACTTCGACCGATTTTT
CACCCGCCATCCACCAGTTCTAACACCTCCTGACCAGGAAGTCATCAGGAATATTGACCA
ATCAGAATTCGAAGGATTTTCCTTTGTTAACTCTGAATTTTT
Enzyme 23 GenBank Gene ID M13974 Link Image
Enzyme 23 GeneCard ID PRKCB Link Image
Enzyme 23 GenAtlas ID Not Available
Enzyme 23 HGNC ID Not Available
Enzyme 23 Chromosome Location Chromosome:1
Enzyme 23 Locus 16p11.2
Enzyme 23 SNPs SNPJam Report Link Image
Enzyme 23 General References
  1. [PubMed Link Image]
Enzyme 23 Metabolite References Not Available
Enzyme 24 [top]
Enzyme 24 ID 1203
Enzyme 24 Name Protein kinase C gamma type
Enzyme 24 Synonyms
  1. PKC-gamma
Enzyme 24 Gene Name PRKCG
Enzyme 24 Protein Sequence >Protein kinase C gamma type
RPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIGKQGLQCQVCSFVVHR
RCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCE
MNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTSDEIHVTVGEARNLIPMDPNGLSDPY
VKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDF
MGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCNLLQKFEACNYPLELYERV
RTGPSSSPIPSPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDE
LYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVME
YVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIK
ITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPF
DGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPAKRLGSGPDGEPTIRAHGFFR
WIDWDRLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRLVLASIDQAEFQGFTY
VNPDFVHPDARSPISPTPVPVM
Enzyme 24 Number of Residues 682
Enzyme 24 Molecular Weight 77155.7
Enzyme 24 Theoretical pI 7.71
Enzyme 24 GO Classification
Function
Process
Component
Enzyme 24 General Function Involved in ATP binding
Enzyme 24 Specific Function PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters
Enzyme 24 Pathways Not Available
Enzyme 24 Reactions Not Available
Enzyme 24 Pfam Domain Function
Enzyme 24 Signals
  • None
Enzyme 24 Transmembrane Regions
  • None
Enzyme 24 Essentiality Not Available
Enzyme 24 GenBank ID Protein 163526 Link Image
Enzyme 24 UniProtKB/Swiss-Prot ID P05128 Link Image
Enzyme 24 UniProtKB/Swiss-Prot Entry Name KPCG_BOVIN Link Image
Enzyme 24 PDB ID Not Available
Enzyme 24 Cellular Location Not Available
Enzyme 24 Gene Sequence Not Available
Enzyme 24 GenBank Gene ID M13976 Link Image
Enzyme 24 GeneCard ID PRKCG Link Image
Enzyme 24 GenAtlas ID Not Available
Enzyme 24 HGNC ID Not Available
Enzyme 24 Chromosome Location Chromosome:1
Enzyme 24 Locus 19q13.4
Enzyme 24 SNPs SNPJam Report Link Image
Enzyme 24 General References
  1. [PubMed Link Image]
Enzyme 24 Metabolite References Not Available
Enzyme 25 [top]
Enzyme 25 ID 1215
Enzyme 25 Name Protein kinase C alpha type
Enzyme 25 Synonyms
  1. PKC-alpha
  2. PKC-A
Enzyme 25 Gene Name PRKCA
Enzyme 25 Protein Sequence >Protein kinase C alpha type
MADVFPAAEPAAPQDVANRFARKGALRQKNVHEVKNHRFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPRWDESFTFKLKPSDKDRRL
SEEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE
LRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG
TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV
NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA
DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG
EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRI
DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN
PQFVHPILQSAV
Enzyme 25 Number of Residues 672
Enzyme 25 Molecular Weight 76836.5
Enzyme 25 Theoretical pI 7.05
Enzyme 25 GO Classification
Function
Process
Component
Enzyme 25 General Function Involved in ATP binding
Enzyme 25 Specific Function PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters
Enzyme 25 Pathways Not Available
Enzyme 25 Reactions Not Available
Enzyme 25 Pfam Domain Function
Enzyme 25 Signals
  • None
Enzyme 25 Transmembrane Regions
  • None
Enzyme 25 Essentiality Not Available
Enzyme 25 GenBank ID Protein 163530 Link Image
Enzyme 25 UniProtKB/Swiss-Prot ID P04409 Link Image
Enzyme 25 UniProtKB/Swiss-Prot Entry Name KPCA_BOVIN Link Image
Enzyme 25 PDB ID Not Available
Enzyme 25 Cellular Location Not Available
Enzyme 25 Gene Sequence >2019 bp
GGCAGGAGGCGGCGAGGGACCATGGCTGACGTCTTCCCGGCCGCCGAGCCGGCGGCGCCG
CAGGACGTGGCCAACCGCTTCGCCCGCAAAGGGGCGCTGAGGCAGAAGAACGTGCACGAG
GTGAAGAACCACCGCTTCATCGCGCGCTTCTTCAAGCAGCCCACCTTCTGCAGCCACTGC
ACCGACTTCATCTGGGGGTTTGGGAAACAAGGCTTCCAGTGCCAAGTTTGCTGTTTTGTG
GTTCACAAGAGGTGCCATGAATTTGTTACTTTTTCTTGTCCGGGGGCGGATAAAGGACCC
GACACAGATGACCCGAGGAGCAAGCACAAGTTCAAGATCCACACGTATGGCAGCCCCACC
TTCTGTGATCACTGCGGCTCCCTGCTCTACGGACTCATCCACCAGGGGATGAAATGTGAC
ACCTGTGATATGAACGTGCACAAGCAGTGCGTGATCAACGTGCCCAGCCTCTGCGGGATG
GACCACACGGAGAAGAGGGGCCGCATCTACCTGAAGGCCGAGGTCACGGATGAAAAGCTG
CACGTCACAGTACGAGACGCGAAAAACCTAATCCCTATGGATCCAAATGGGCTTTCAGAT
CCTTACGTGAAGCTGAAGCTTATTCCTGACCCCAAGAACGAGAGCAAACAGAAAACCAAG
ACCATCCGCTCGACGCTGAACCCCCGGTGGGACGAGTCCTTCACGTTCAAATTAAAACCT
TCTGATAAAGACCGGCGACTGTCCGAGGAAATCTGGGACTGGGATCGAACCACACGGAAC
GACTTCATGGGGTCCCTTTCCTTTGGGGTCTCGGAGCTGATGAAGATGCCGGCCAGCGGA
TGGTACAAGCTGCTGAACCAAGAGGAGGGCGAGTACTACAACGTGCCGATCCCCGAAGGC
GACGAGGAAGGCAATGTGGAGCTCAGGCAGAAATTCGAGAAAGCCAAGCTTGGCCCTGCC
GGCAACAAAGTCATCAGTCCCTCCGAGGACAGGAGACAGCCTTCCAACAACCTGGACAGA
GTGAAGCTCACGGACTTCAACTTCCTCATGGTGCTGGGCAAAGGCAGCTTTGGGAAGGTG
ATGCTGGCCGACCGGAAGGGGACAGAGGAGCTGTACGCCATCAAGATCCTGAAGAAGGAC
GTGGTCATCCAGGACGACGACGTGGAGTGCACCATGGTGGAGAAGCGGGTCCTGGCGCTG
CTCGACAAGCCGCCGTTCCTGACGCAGCTGCACTCCTGCTTCCAGACGGTGGACCGGCTG
TACTTCGTCATGGAGTACGTCAACGGCGGGGACCTCATGTACCACATCCAGCAGGTCGGG
AAGTTCAAGGAGCCGCAAGCAGTGTTCTATGCAGCAGAGATTTCCATCGGGCTGTTCTTT
CTTCATAAAAGAGGAATCATTTATCGGGACCTGAAGTTAGACAACGTCATGCTGGACTCG
GAAGGACACATTAAGATCGCGGACTTCGGGATGTGCAAGGAGCACATGATGGACGGCGTC
ACGACCAGGACCTTCTGCGGGACCCCCGACTACATCGCCCCAGAGATAATCGCCTATCAG
CCGTACGGGAAGTCCGTGGACTGGTGGGCCTACGGCGTCCTGTTGTACGAGATGTTGGCC
GGGCAGCCTCCGTTCGACGGCGAGGACGAGGACGAGCTGTTCCAGTCCATCATGGAGCAC
AACGTCTCGTACCCCAAGTCCTTGTCCAAGGAGGCCGTGTCCATCTGCAAAGGGCTGATG
ACCAAGCACCCCGGGAAGCGGCTGGGCTGCGGGCCCGAGGGCGAGCGCGACGTGCGGGAG
CATGCCTTCTTCCGGAGGATCGACTGGGAGAAGCTGGAGAACCGTGAGATCCAGCCACCC
TTCAAGCCCAAAGTGTGCGGCAAAGGAGCAGAGAACTTTGACAAGTTCTTCACGCGAGGG
CAGCCTGTCTTGACGCCGCCCGACCAGCTGGTCATCGCTAACATCGACCAGTCTGATTTT
GAAGGCTTCTCCTACGTCAACCCCCAGTTCGTGCACCCC
Enzyme 25 GenBank Gene ID M13973 Link Image
Enzyme 25 GeneCard ID PRKCA Link Image
Enzyme 25 GenAtlas ID Not Available
Enzyme 25 HGNC ID Not Available
Enzyme 25 Chromosome Location Chromosome:1
Enzyme 25 Locus 17q22-q23.2
Enzyme 25 SNPs SNPJam Report Link Image
Enzyme 25 General References
  1. [PubMed Link Image]
Enzyme 25 Metabolite References Not Available
Enzyme 26 [top]
Enzyme 26 ID 1299
Enzyme 26 Name Guanylyl cyclase-activating protein 1
Enzyme 26 Synonyms
  1. GCAP 1
  2. Guanylate cyclase activator 1A
Enzyme 26 Gene Name GUCA1A
Enzyme 26 Protein Sequence >Guanylyl cyclase-activating protein 1
MGNIMDGKSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMF
ETFDFNKDGYIDFMEYVAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIR
AINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTRIV
RRLQNGEQDEEGASGRETEAAEADG
Enzyme 26 Number of Residues 205
Enzyme 26 Molecular Weight 23510.2
Enzyme 26 Theoretical pI 4.14
Enzyme 26 GO Classification
Function
Process
Component
Enzyme 26 General Function Involved in calcium ion binding
Enzyme 26 Specific Function Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure
Enzyme 26 Pathways Not Available
Enzyme 26 Reactions Not Available
Enzyme 26 Pfam Domain Function
Enzyme 26 Signals
  • None
Enzyme 26 Transmembrane Regions
  • None
Enzyme 26 Essentiality Not Available
Enzyme 26 GenBank ID Protein 1174356 Link Image
Enzyme 26 UniProtKB/Swiss-Prot ID P46065 Link Image
Enzyme 26 UniProtKB/Swiss-Prot Entry Name GUC1A_BOVIN Link Image
Enzyme 26 PDB ID Not Available
Enzyme 26 Cellular Location Not Available
Enzyme 26 Gene Sequence >618 bp
ATGGGGAACATTATGGACGGTAAGTCGGTGGAGGAGCTGAGCAGCACCGAGTGCCACCAG
TGGTACAAGAAGTTCATGACAGAGTGCCCCTCCGGCCAGCTCACCCTCTACGAGTTCCGC
CAGTTCTTCGGCCTCAAGAACCTGAGCCCGTGGGCCAGCCAGTACGTGGAGCAGATGTTT
GAGACCTTTGACTTCAACAAAGACGGCTACATTGATTTCATGGAGTACGTGGCGGCTCTG
AGCCTGGTCCTCAAGGGGAAGGTGGAACAGAAGCTGCGTTGGTACTTCAAGCTCTACGAC
GTGGACGGCAACGGATGCATCGACCGCGACGAGCTGCTCACCATCATCCGGGCCATCCGA
GCCATTAACCCCTGCAGCGACTCGACCATGACCGCCGAGGAGTTCACCGATACAGTGTTC
TCCAAGATTGACGTCAATGGGGATGGGGAACTCTCCCTAGAGGAGTTCATGGAGGGCGTC
CAGAAGGACCAGATGCTCTTGGACACGCTGACCCGAAGCTTGGACCTTACCCGCATTGTG
CGCAGGCTCCAGAATGGAGAGCAGGATGAGGAGGGGGCTAGCGGCAGGGAAACGGAGGCC
GCGGAGGCCGACGGCTGA
Enzyme 26 GenBank Gene ID X95352 Link Image
Enzyme 26 GeneCard ID GUCA1A Link Image
Enzyme 26 GenAtlas ID Not Available
Enzyme 26 HGNC ID Not Available
Enzyme 26 Chromosome Location Chromosome:6
Enzyme 26 Locus 6p21.1
Enzyme 26 SNPs SNPJam Report Link Image
Enzyme 26 General References
  1. [PubMed Link Image]
Enzyme 26 Metabolite References Not Available
Enzyme 27 [top]
Enzyme 27 ID 1300
Enzyme 27 Name Glucosidase 2 subunit beta
Enzyme 27 Synonyms
  1. Glucosidase II subunit beta
  2. Protein kinase C substrate 60.1 kDa protein heavy chain
  3. PKCSH
  4. 80K-H protein
  5. Vacuolar system-associated protein 60
  6. VASAP-60
Enzyme 27 Gene Name PRKCSH
Enzyme 27 Protein Sequence >Glucosidase 2 subunit beta
MLLLLLLLPMCWAVEVRRPRGVSLTNHHFYDESKPFTCLDGSASIPFDQVNDDYCDCKDG
SDEPGTAACPNGSFHCTNTGYKALYISSRWVNDGVCDCCDGTDEYNSGIVCENTCKEKGR
KERETLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEVLRTLKE
EAEKPEEAAKDQHRRLWEEQQAISKEQRERELAASAFQELDDDMDGAVSVAELQTHPELD
TDGDGALSEGEAQTLLGGDAQMDAAFFYDRVWAAIRDKYRSEVLPTEYPPSPPAPDVMEP
KEEQPPMPSPPTEEEDEDEEDEETEEDEDEEDEDSQGEQPKDAPPPAPAPQTASPTEEDR
MPPYDEQTQAFINAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQC
YELTTNEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQGP
NRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEYPVEGDHDEL
Enzyme 27 Number of Residues 533
Enzyme 27 Molecular Weight 60150.7
Enzyme 27 Theoretical pI 4.08
Enzyme 27 GO Classification
Function
Process
Component
Enzyme 27 General Function Involved in calcium ion binding
Enzyme 27 Specific Function Regulatory subunit of glucosidase II
Enzyme 27 Pathways
  • Glycan metabolism
  • N-glycan metabolism
Enzyme 27 Reactions Not Available
Enzyme 27 Pfam Domain Function
Enzyme 27 Signals
  • 1-13
Enzyme 27 Transmembrane Regions
  • None
Enzyme 27 Essentiality Not Available
Enzyme 27 GenBank ID Protein 1215746 Link Image
Enzyme 27 UniProtKB/Swiss-Prot ID Q28034 Link Image
Enzyme 27 UniProtKB/Swiss-Prot Entry Name GLU2B_BOVIN Link Image
Enzyme 27 PDB ID Not Available
Enzyme 27 Cellular Location Not Available
Enzyme 27 Gene Sequence >1602 bp
ATGTTACTGCTGCTGCTGCTACTGCCGATGTGTTGGGCCGTGGAAGTCAGGCGACCCCGG
GGCGTCTCCCTCACCAACCATCACTTCTACGACGAGTCAAAGCCTTTCACTTGCCTGGAT
GGCTCTGCCAGTATCCCCTTTGATCAGGTCAATGATGACTACTGTGACTGCAAAGATGGC
TCAGATGAACCAGGCACAGCTGCCTGTCCCAACGGCAGCTTCCACTGCACCAACACAGGC
TACAAGGCCCTGTACATCTCCTCCAGATGGGTCAACGATGGAGTGTGTGACTGCTGTGAC
GGGACCGACGAATACAACAGCGGGATCGTTTGTGAGAACACCTGCAAAGAGAAGGGCCGC
AAGGAGAGAGAGACACTGCAGCAGATGGCAGAGGTGACCCGCGAGGGCTTCCGCCTGAAG
AAGATCCTGATTGAGGACTGGAAGAAGGCCCGGGAGGAGAAGCAGAAAAAGCTCATTGAG
CTGCAGGCTGGAAAGAAGTCACTGGAGGACCAGGTGGAGGTGCTGCGGACCCTGAAGGAG
GAAGCCGAGAAGCCAGAGGAGGCGGCCAAAGACCAGCACCGCAGGCTGTGGGAAGAGCAG
CAGGCCATCTCCAAGGAGCAGCGGGAGCGGGAGCTGGCAGCCAGCGCCTTCCAGGAGCTG
GATGATGACATGGATGGCGCGGTCTCAGTGGCTGAGCTGCAGACCCACCCAGAGCTGGAC
ACGGATGGGGACGGGGCATTATCAGAAGGGGAAGCCCAGACCCTCCTTGGGGGAGACGCG
CAGATGGATGCTGCTTTCTTCTATGACCGTGTCTGGGCCGCCATCAGGGACAAGTACCGG
TCCGAGGTGCTGCCCACTGAGTACCCACCATCGCCTCCTGCACCCGATGTGATGGAGCCC
AAGGAGGAGCAGCCCCCCATGCCCTCACCGCCCACAGAGGAGGAGGACGAAGACGAGGAG
GACGAGGAGACAGAGGAGGATGAGGATGAGGAGGACGAGGATTCCCAGGGGGAGCAGCCC
AAGGACGCCCCACCCCCAGCCCCAGCCCCCCAGACGGCCAGCCCCACCGAGGAGGATAGG
ATGCCGCCGTATGATGAGCAGACGCAGGCCTTCATCAATGCTGCCCAGGAGGCCCGCAAC
AAGTTCGAAGAGGCTGAGCGGTCCCTGAAGGACATGGAAGAATCCATCAGGAACCTGGAA
CAGGAGATTTCATTTGATTTTGGCCCCAACGGCGAGTTCGCCTACCTGTACAGCCAGTGC
TATGAGCTCACCACCAATGAGTACGTCTACAGACTCTGCCCCTTCAAGCTTGTCTCACAG
AAACCCAAACTCGGCGGCTCCCCTACCAGCCTTGGCACCTGGGGCTCGTGGGCTGGCCCC
GACCACGACAAGTTCAGCGCCATGAAGTATGAGCAGGGCACAGGCTGCTGGCAGGGCCCC
AATCGCTCCACCACCGTGCGCCTGCTGTGCGGGAAGGAGACGGTGGTGACCAGCACCACA
GAGCCCAGCCGCTGCGAGTACCTCATGGAGCTGATGACGCCAGCTGCCTGCCCAGAGCCC
CCGCCTGAATACCCAGTGGAGGGCGACCATGATGAGCTCTAG
Enzyme 27 GenBank Gene ID U49178 Link Image
Enzyme 27 GeneCard ID PRKCSH Link Image
Enzyme 27 GenAtlas ID Not Available
Enzyme 27 HGNC ID Not Available
Enzyme 27 Chromosome Location Chromosome:1
Enzyme 27 Locus 19p13.2
Enzyme 27 SNPs SNPJam Report Link Image
Enzyme 27 General References
  1. [PubMed Link Image]
Enzyme 27 Metabolite References Not Available
Enzyme 28 [top]
Enzyme 28 ID 1301
Enzyme 28 Name Calpain small subunit 1
Enzyme 28 Synonyms
  1. CSS1
  2. Calcium-dependent protease small subunit 1
  3. Calcium-dependent protease small subunit
  4. CDPS
  5. Calpain regulatory subunit
  6. Calcium-activated neutral proteinase small subunit
  7. CANP small subunit
Enzyme 28 Gene Name CAPNS1
Enzyme 28 Protein Sequence >Calpain small subunit 1
MFLVNSFLKGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGTAMRILGGV
ISAISEAAAQYNPEPVPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILN
KVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAVYKQFDVDR
SGTIGSSELPGAFEAAGFRLNEHLYNMIIRRYSDEGGNMDFDNFISCLVRLDAMFRAFKS
LDKDGTGQIQVNIQEWLQLTMYS
Enzyme 28 Number of Residues 263
Enzyme 28 Molecular Weight 27931.3
Enzyme 28 Theoretical pI 4.82
Enzyme 28 GO Classification
Function
Process
Component
Enzyme 28 General Function Carbohydrate transport and metabolism
Enzyme 28 Specific Function Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction
Enzyme 28 Pathways Not Available
Enzyme 28 Reactions Not Available
Enzyme 28 Pfam Domain Function Not Available
Enzyme 28 Signals
  • None
Enzyme 28 Transmembrane Regions
  • None
Enzyme 28 Essentiality Not Available
Enzyme 28 GenBank ID Protein 162781 Link Image
Enzyme 28 UniProtKB/Swiss-Prot ID P13135 Link Image
Enzyme 28 UniProtKB/Swiss-Prot Entry Name CPNS1_BOVIN Link Image
Enzyme 28 PDB ID 1KFU Link Image
Enzyme 28 PDB File Show
Enzyme 28 3D Structure
Enzyme 28 Cellular Location Not Available
Enzyme 28 Gene Sequence >792 bp
ATGTTCCTGGTTAACTCGTTCTTGAAGGGTGGCGGAGGCGGCGGAGGAGGCGGGGGCCTG
GGCGGGGGTCTAGGGAATGTGCTTGGAGGCCTTATCAGCGGGGCTGGAGGCGGCGGCGGA
GGCGGAGGCGGCGGCGGCGGTGGCGGCGGCGGAACCGCAATGCGCATCCTGGGCGGGGTC
ATTAGCGCCATTAGTGAGGCGGCTGCCCAGTACAACCCAGAGCCCGTGCCCCCTCGCACA
CATTACTCCAACATTGAGGCCAATGAGAGTGAGGAGGTCCGGCAGTTCCGGAGGCTTTTT
GCCCAGCTGGCTGGAGATGACATGGAGGTCAGCGCCACAGAACTCATGAACATTCTCAAC
AAAGTGGTGACCCGACATCCTGATCTGAAGACTGATGGCTTTGGCATTGACACATGTCGC
AGCATGGTGGCTGTAATGGATAGTGACACGACTGGCAAACTGGGCTTCGAAGAATTCAAG
TACTTGTGGAACAACATCAAAAAGTGGCAGGCCGTATACAAACAGTTTGATGTTGACCGT
TCAGGGACCATTGGCAGCAGTGAACTCCCAGGGGCCTTTGAGGCAGCAGGATTCCGCCTG
AATGAACATCTCTACAACATGATCATCCGACGCTACTCAGATGAGGGAGGGAACATGGAT
TTTGACAATTTCATCAGCTGCCTGGTCAGACTGGATGCCATGTTCCGTGCCTTCAAATCT
CTCGACAAAGATGGCACTGGACAAATCCAGGTGAACATCCAGGAGTGGCTGCAGCTGACC
ATGTACTCCTGA
Enzyme 28 GenBank Gene ID J05065 Link Image
Enzyme 28 GeneCard ID CAPNS1 Link Image
Enzyme 28 GenAtlas ID Not Available
Enzyme 28 HGNC ID Not Available
Enzyme 28 Chromosome Location Chromosome:1
Enzyme 28 Locus 19q13.12
Enzyme 28 SNPs SNPJam Report Link Image
Enzyme 28 General References
  1. [PubMed Link Image]
Enzyme 28 Metabolite References Not Available
Enzyme 29 [top]
Enzyme 29 ID 1302
Enzyme 29 Name Calcineurin subunit B type 2
Enzyme 29 Synonyms
  1. Protein phosphatase 2B regulatory subunit 2
  2. Protein phosphatase 3 regulatory subunit B beta isoform
Enzyme 29 Gene Name PPP3R2
Enzyme 29 Protein Sequence >Calcineurin subunit B type 2
MGNEASYPAEICSHFDEDEIKRLRKRFKKLDLDSSSALSVKEFTSMPELQENPLVQRVID
VFDTDGDGQVDFREFILGTSQFSVRGDEEQKLRFAFSIYDMDKDGYISNGELFQVLKMMV
GDNLKDWQLQQLVDKTIILLDKDGDGKISFQEFSAVVRSLEIHKHLVTIV
Enzyme 29 Number of Residues 170
Enzyme 29 Molecular Weight 19548.0
Enzyme 29 Theoretical pI 4.47
Enzyme 29 GO Classification
Function
Process
Component
Enzyme 29 General Function Involved in calcium ion binding
Enzyme 29 Specific Function Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity
Enzyme 29 Pathways Not Available
Enzyme 29 Reactions Not Available
Enzyme 29 Pfam Domain Function
Enzyme 29 Signals
  • None
Enzyme 29 Transmembrane Regions
  • None
Enzyme 29 Essentiality Not Available
Enzyme 29 GenBank ID Protein 83759133 Link Image
Enzyme 29 UniProtKB/Swiss-Prot ID Q2TBI5 Link Image
Enzyme 29 UniProtKB/Swiss-Prot Entry Name CANB2_BOVIN Link Image
Enzyme 29 PDB ID Not Available
Enzyme 29 Cellular Location Not Available
Enzyme 29 Gene Sequence >513 bp
ATGGGAAATGAGGCCAGTTACCCGGCGGAGATATGCTCGCACTTCGACGAAGATGAAATT
AAAAGGCTGCGCAAGCGTTTTAAGAAGCTGGACTTGGACAGTTCCAGCGCTCTGAGCGTC
AAAGAGTTCACGTCCATGCCAGAGCTGCAGGAGAACCCGCTGGTGCAGCGGGTGATAGAC
GTCTTCGACACCGACGGCGACGGACAGGTGGACTTCCGGGAATTCATCCTGGGGACCTCC
CAGTTCAGCGTCCGGGGAGATGAGGAGCAGAAGCTGAGGTTTGCTTTCAGCATCTACGAC
ATGGACAAAGACGGCTACATTTCCAACGGGGAGCTCTTCCAGGTGCTGAAGATGATGGTA
GGCGACAACCTGAAAGACTGGCAGTTACAGCAGCTGGTGGACAAAACCATCATCCTCCTG
GACAAAGACGGGGACGGGAAAATCTCCTTCCAGGAATTCAGTGCTGTGGTCAGAAGCCTG
GAGATCCACAAGCACTTGGTGACCATTGTGTGA
Enzyme 29 GenBank Gene ID BC110140 Link Image
Enzyme 29 GeneCard ID PPP3R2 Link Image
Enzyme 29 GenAtlas ID Not Available
Enzyme 29 HGNC ID Not Available
Enzyme 29 Chromosome Location Chromosome:9
Enzyme 29 Locus 9q31.1
Enzyme 29 SNPs SNPJam Report Link Image
Enzyme 29 General References Not Available
Enzyme 29 Metabolite References Not Available
Enzyme 30 [top]
Enzyme 30 ID 1303
Enzyme 30 Name Complement C1s subcomponent
Enzyme 30 Synonyms
  1. C1 esterase
  2. Complement C1s subcomponent heavy chain
  3. Complement C1s subcomponent light chain
Enzyme 30 Gene Name C1S
Enzyme 30 Protein Sequence >Complement C1s subcomponent
MWCIVLFSLVAWVYAEPTMYGEILSPNYPQVYPNEVEKSWDIEVPAGYGIHLYFTHLDIE
LSENCSYDSVQIMSGGHEEGKLCGRRTNKNSNSPVVKEFHIPYSKLQVIFRSDFSNEERF
TGFAAYYVAEDIDECTAFADAPCSHFCNNFLGGYFCSCPPEYFLHEDKKNCGVNCSGNVF
TTMTGEVESPNYPSPYPESSRCDYQIQLEEGFRVVVTMRREDFDVEPADSEGHCPDSLLF
VAGDQHFGPYCGNGFPGPLTIETQSSALNIIFQTDGSEQRKGWKFRYHGDPIPCPKEVTA
NSFWEPERAKYVFRDVVKITCVDGFEVVQGSVGSPSFYSTCQSNGKWSNSKLRCQPVDCG
APEPIQHGRVEDPESTLFGSITRYSCEMPYYSMECEGSEVYHCSGNGSWVNKVLGIEPPK
CIAVCGTPSEPFRSTQRIFGGSIAKIENFPWQVFFSNPWAGGALIDEYWVLTAAHVVEGN
DIPVMYVGSSSVVTSQLSNAQMLTAERVFIHPGWEVLDPSITRKNFDNDIALVRLRDPVK
MGPKVAPICLPGTSSEYDPPENVLGLISGWGRTNVKSHVIKLRGAKLPVAPLSKCREMKG
VNPGIDISSFVFTENMICAGNDKGVDSCDGDSGGAFAVQDPKENKPKFYVAGLVSWGPQC
GTYGIYTRVKNYVDWIRKTMQEYSAPSVD
Enzyme 30 Number of Residues 689
Enzyme 30 Molecular Weight 76608.7
Enzyme 30 Theoretical pI 4.72
Enzyme 30 GO Classification
Function
Process
Component
Enzyme 30 General Function Involved in calcium ion binding
Enzyme 30 Specific Function C1s B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4
Enzyme 30 Pathways Not Available
Enzyme 30 Reactions Not Available
Enzyme 30 Pfam Domain Function
Enzyme 30 Signals
  • 1-15
Enzyme 30 Transmembrane Regions
  • None
Enzyme 30 Essentiality Not Available
Enzyme 30 GenBank ID Protein 111307513 Link Image
Enzyme 30 UniProtKB/Swiss-Prot ID Q0VCX1 Link Image
Enzyme 30 UniProtKB/Swiss-Prot Entry Name C1S_BOVIN Link Image
Enzyme 30 PDB ID Not Available
Enzyme 30 Cellular Location Not Available
Enzyme 30 Gene Sequence >2088 bp
ATGAACAAATTGCCAGAGATGTGGTGCATTGTCCTGTTTTCCCTTGTGGCCTGGGTTTAT
GCCGAGCCTACTATGTATGGAGAGATTCTATCCCCCAACTACCCTCAGGTGTACCCCAAC
GAGGTCGAGAAGTCTTGGGACATAGAAGTCCCTGCAGGGTACGGGATCCACCTTTACTTC
ACCCACCTGGATATAGAGTTGTCTGAGAACTGCTCCTATGATTCAGTGCAGATAATGTCG
GGAGGCCATGAAGAAGGGAAACTCTGTGGACGGAGGACCAACAAGAATTCAAACTCCCCA
GTGGTGAAAGAGTTCCACATCCCATACAGTAAATTGCAGGTGATCTTCCGGTCGGACTTC
TCCAACGAGGAGCGTTTCACCGGGTTTGCTGCGTACTATGTTGCTGAGGATATAGATGAG
TGCACAGCCTTTGCAGATGCTCCTTGCAGCCACTTCTGCAATAACTTCCTTGGTGGTTAC
TTCTGCTCCTGCCCTCCAGAATACTTCCTCCATGAAGACAAGAAGAACTGTGGAGTCAAT
TGCAGTGGAAATGTATTCACCACAATGACTGGGGAGGTTGAAAGTCCTAATTACCCCAGT
CCATACCCAGAGAGCTCAAGGTGTGACTATCAGATCCAGTTGGAGGAGGGGTTCCGAGTG
GTGGTGACCATGAGGAGAGAAGACTTTGATGTGGAACCAGCTGACTCCGAGGGCCACTGT
CCCGACAGTTTGCTCTTTGTGGCAGGAGACCAGCATTTTGGTCCTTACTGTGGGAACGGC
TTTCCTGGGCCACTAACAATTGAAACCCAGAGCAGTGCTCTGAATATCATCTTCCAAACT
GATGGATCAGAACAAAGAAAGGGATGGAAATTTCGTTACCATGGAGATCCAATCCCTTGT
CCTAAAGAAGTCACTGCCAATTCCTTCTGGGAGCCTGAGAGAGCAAAATATGTGTTCAGA
GATGTGGTGAAGATAACCTGTGTGGATGGGTTTGAAGTTGTGCAGGGAAGTGTTGGTTCC
CCATCTTTCTACTCTACTTGTCAAAGCAATGGAAAGTGGAGTAATTCCAAGTTGCGGTGT
CAACCCGTGGACTGTGGCGCTCCTGAACCCATTCAGCATGGTAGAGTCGAAGATCCAGAA
AGTACTCTATTTGGTTCCATCACTCGCTACTCTTGTGAGATGCCATATTACAGCATGGAA
TGTGAAGGGAGCGAGGTGTATCACTGCAGTGGCAATGGGAGCTGGGTGAACAAGGTGCTG
GGCATAGAGCCGCCGAAATGCATTGCAGTCTGTGGCACCCCCAGCGAGCCTTTTAGATCA
ACACAAAGAATATTTGGAGGCTCCATTGCGAAGATTGAAAATTTCCCCTGGCAAGTCTTC
TTCTCGAACCCATGGGCTGGTGGGGCTCTCATTGATGAATACTGGGTGCTGACAGCTGCC
CATGTCGTGGAGGGAAACGATATCCCAGTGATGTATGTTGGGTCCTCCTCAGTGGTCACC
TCACAATTGTCAAATGCTCAGATGCTCACTGCAGAGAGAGTGTTTATCCATCCAGGATGG
GAGGTCCTGGATCCTTCGATAACACGAAAGAATTTTGACAATGACATTGCGCTGGTGCGG
CTGAGAGACCCAGTGAAAATGGGACCCAAGGTCGCCCCTATCTGCCTACCAGGCACCTCC
TCAGAATATGACCCTCCGGAGAACGTCCTGGGCCTGATCTCAGGTTGGGGTCGAACAAAT
GTCAAAAGTCATGTTATTAAGCTCAGAGGGGCAAAGCTACCCGTTGCTCCCTTATCCAAA
TGCCGGGAGATGAAGGGGGTCAATCCTGGAATAGATATCAGTTCTTTTGTTTTCACTGAG
AACATGATCTGTGCCGGTAATGACAAGGGTGTTGACAGCTGTGACGGGGACAGTGGTGGG
GCCTTTGCTGTACAGGACCCTAAGGAAAACAAGCCCAAATTCTATGTTGCTGGTTTGGTG
TCCTGGGGCCCCCAGTGTGGGACCTATGGGATCTACACGCGAGTCAAGAACTACGTTGAC
TGGATAAGGAAGACAATGCAGGAGTATAGTGCCCCCAGTGTAGACTAA
Enzyme 30 GenBank Gene ID BC119956 Link Image
Enzyme 30 GeneCard ID C1S Link Image
Enzyme 30 GenAtlas ID Not Available
Enzyme 30 HGNC ID Not Available
Enzyme 30 Chromosome Location Chromosome:1
Enzyme 30 Locus 12p13
Enzyme 30 SNPs SNPJam Report Link Image
Enzyme 30 General References Not Available
Enzyme 30 Metabolite References Not Available
Enzyme 31 [top]
Enzyme 31 ID 1304
Enzyme 31 Name Alpha-lactalbumin
Enzyme 31 Synonyms
  1. Lactose synthase B protein
Enzyme 31 Gene Name LALBA
Enzyme 31 Protein Sequence >Alpha-lactalbumin
MMSFVSLLLVGILFHATQAEQLTKCEVFRELKDLKGYGGVSLPEWVCTTFHTSGYDTQAI
VQNNDSTEYGLFQINNKIWCKDDQNPHSSNICNISCDKFLDDDLTDDIMCVKKILDKVGI
NYWLAHKALCSEKLDQWLCEKL
Enzyme 31 Number of Residues 142
Enzyme 31 Molecular Weight 16246.5
Enzyme 31 Theoretical pI 4.73
Enzyme 31 GO Classification
Function
Process
Component
Enzyme 31 General Function Involved in calcium ion binding
Enzyme 31 Specific Function Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins
Enzyme 31 Pathways Not Available
Enzyme 31 Reactions Not Available
Enzyme 31 Pfam Domain Function
Enzyme 31 Signals
  • 1-19
Enzyme 31 Transmembrane Regions
  • None
Enzyme 31 Essentiality Not Available
Enzyme 31 GenBank ID Protein 163283 Link Image
Enzyme 31 UniProtKB/Swiss-Prot ID P00711 Link Image
Enzyme 31 UniProtKB/Swiss-Prot Entry Name LALBA_BOVIN Link Image
Enzyme 31 PDB ID 1F6S Link Image
Enzyme 31 PDB File Show
Enzyme 31 3D Structure
Enzyme 31 Cellular Location Not Available
Enzyme 31 Gene Sequence >429 bp
AMOFALUISITE.TAACCAAAATGATGTCCTTTGTCTCTCTGCTCCTGGTAGGCATCCTA
TTCCATGCCACCCAGGCTGAACAGTTAACAAAATGTGAGGTGTTCCGGGAGCTGAAAGAC
TTGAAGGGCTACGGAGGTGTCAGTTTGCCTGAATGGGTCTGTACCACGTTTCATACCAGT
GGTTATGACACACAAGCCATAGTACAAAACAATGACAGCACAGAATATGGACTCTTCCAG
ATAAATAATAAAATTTGGTGCAAAGACGACCAGAACCCTCACTCAAGCAACATCTGTAAC
ATCTCCTGTGACAAGTTCCTGGATGATGATCTTACTGATGACATTATGTGTGTCAAGAAG
ATTCTGGATAAAGTAGGAATTAACTACTGGTTGGCCCATAAAGCACTCTGTTCTGAGAAG
CTGGATCAG
Enzyme 31 GenBank Gene ID M18780 Link Image
Enzyme 31 GeneCard ID LALBA Link Image
Enzyme 31 GenAtlas ID Not Available
Enzyme 31 HGNC ID Not Available
Enzyme 31 Chromosome Location Chromosome:1
Enzyme 31 Locus 12q13
Enzyme 31 SNPs SNPJam Report Link Image
Enzyme 31 General References
  1. [PubMed Link Image]
Enzyme 31 Metabolite References Not Available
Enzyme 32 [top]
Enzyme 32 ID 1305
Enzyme 32 Name Deoxyribonuclease-1
Enzyme 32 Synonyms
  1. Deoxyribonuclease I
  2. DNase I
Enzyme 32 Gene Name DNASE1
Enzyme 32 Protein Sequence >Deoxyribonuclease-1
MRGTRLMGLLLALAGLLQLGLSLKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQ
EVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYD
DGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKW
HLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAG
SLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
Enzyme 32 Number of Residues 282
Enzyme 32 Molecular Weight 31345.2
Enzyme 32 Theoretical pI 5.31
Enzyme 32 GO Classification
Function
Process
Component
Enzyme 32 General Function Involved in actin binding
Enzyme 32 Specific Function Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization
Enzyme 32 Pathways Not Available
Enzyme 32 Reactions Not Available
Enzyme 32 Pfam Domain Function
Enzyme 32 Signals
  • 1-22
Enzyme 32 Transmembrane Regions
  • None
Enzyme 32 Essentiality Not Available
Enzyme 32 GenBank ID Protein 2546888 Link Image
Enzyme 32 UniProtKB/Swiss-Prot ID P00639 Link Image
Enzyme 32 UniProtKB/Swiss-Prot Entry Name DNAS1_BOVIN Link Image
Enzyme 32 PDB ID 3DNI Link Image
Enzyme 32 PDB File Show
Enzyme 32 3D Structure
Enzyme 32 Cellular Location Not Available
Enzyme 32 Gene Sequence >849 bp
ATGAGGGGCACCAGGCTGATGGGGCTGCTGCTCGCCCTCGCTGGTCTGCTGCAGCTGGGC
TTGTCCCTGAAGATAGCAGCCTTCAACATCCGCACCTTTGGGGAGACCAAGATGTCCAAT
GCTACGCTCGCCAGCTACATTGTTCGGATCGTGCGTCGTTACGACATCGTCCTCATCCAG
GAGGTCAGAGACAGCCACCTGGTGGCTGTGGGGAAGCTCCTGGACTATCTCAACCAGGAT
GACCCAAACACCTACCACTATGTGGTCAGTGAGCCGCTGGGCCGCAACAGCTACAAGGAG
CGCTACCTCTTTCTGTTCAGACCCAACAAGGTGTCCGTGCTGGACACCTACCAGTACGAC
GACGGCTGCGAGTCCTGCGGGAACGACAGCTTCAGCCGGGAGCCCGCTGTGGTCAAGTTC
TCATCCCACTCCACCAAGGTCAAGGAATTTGCCATTGTTGCCCTGCACTCGGCCCCATCG
GACGCAGTGGCTGAGATTAATTCTCTCTACGATGTCTACCTGGATGTCCAGCAGAAGTGG
CACTTGAACGATGTCATGTTGATGGGCGATTTCAATGCTGACTGCAGCTACGTGACCTCC
TCGCAGTGGTCATCCATCCGCCTGCGTACGAGCTCCACCTTCCAGTGGCTGATTCCTGAC
AGTGCCGACACCACGGCTACGTCCACGAACTGCGCCTATGACAGGATCGTGGTCGCAGGG
TCTCTGCTCCAGAGTTCTGTGGTTCCTGGCTCGGCCGCTCCCTTTGACTTCCAAGCTGCA
TACGGACTGAGCAATGAGATGGCCCTGGCCATCAGTGACCATTACCCGGTGGAGGTGACG
CTGACATAA
Enzyme 32 GenBank Gene ID AJ001538 Link Image
Enzyme 32 GeneCard ID DNASE1 Link Image
Enzyme 32 GenAtlas ID Not Available
Enzyme 32 HGNC ID Not Available
Enzyme 32 Chromosome Location Chromosome:1
Enzyme 32 Locus 16p13.3
Enzyme 32 SNPs SNPJam Report Link Image
Enzyme 32 General References
  1. [PubMed Link Image]
Enzyme 32 Metabolite References Not Available
Enzyme 33 [top]
Enzyme 33 ID 1306
Enzyme 33 Name Coagulation factor VII
Enzyme 33 Synonyms
  1. Serum prothrombin conversion accelerator
  2. Factor VII light chain
  3. Factor VII heavy chain
Enzyme 33 Gene Name F7
Enzyme 33 Protein Sequence >Coagulation factor VII
MLSQAWALALLCFLLSLWGSLPAVFLPQEQALSILHRPRRANGFLEELLPGSLERECREE
LCSFEEAHEIFRNEERTRQFWVSYNDGDQCASSPCQNGGSCEDQLRSYICFCPDGFEGRN
CETDKQSQLICANDNGGCEQYCGADPGAGRFCWCHEGYALQADGVSCAPTVEYPCGKIPV
LEKRNGSKPQGRIVGGHVCPKGECPWQAMLKLNGALLCGGTLVGPAWVVSAAHCFERLRS
RGNLTAVLGEHDLSRVEGPEQERRVAQIIVPKQYVPGQTDHDVALLQLAQPVALGDHVAP
LCLPDPDFADQTLAFVRFSAVSGWGQLLERGVTARKLMVVLVPRLLTQDCLQQSRQRPGG
PVVTDNMFCAGYSDGSKDACKGDSGGPHATRFRGTWFLTGVVSWGEGCAAAGHFGIYTRV
SRYTAWLRQLMGHPPSRQGFFQVPLLP
Enzyme 33 Number of Residues 447
Enzyme 33 Molecular Weight 48960.3
Enzyme 33 Theoretical pI 6.42
Enzyme 33 GO Classification
Function
Process
Component
Enzyme 33 General Function Involved in calcium ion binding
Enzyme 33 Specific Function Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium
Enzyme 33 Pathways Not Available
Enzyme 33 Reactions Not Available
Enzyme 33 Pfam Domain Function
Enzyme 33 Signals
  • 1-23
Enzyme 33 Transmembrane Regions
  • None
Enzyme 33 Essentiality Not Available
Enzyme 33 GenBank ID Protein 61553619 Link Image
Enzyme 33 UniProtKB/Swiss-Prot ID P22457 Link Image
Enzyme 33 UniProtKB/Swiss-Prot Entry Name FA7_BOVIN Link Image
Enzyme 33 PDB ID Not Available
Enzyme 33 Cellular Location Not Available
Enzyme 33 Gene Sequence >1344 bp
ATGCTGTCCCAGGCCTGGGCTCTGGCCCTCCTCTGCTTTCTGCTCAGCCTGTGGGGGTCC
CTGCCGGCAGTCTTCCTGCCCCAGGAGCAGGCCCTCAGCATCCTGCATCGGCCTCGGCGT
GCCAACGGGTTCCTGGAGGAGCTGCTGCCGGGCTCGCTGGAGCGGGAGTGCAGGGAGGAG
CTCTGCTCCTTCGAGGAAGCCCACGAGATCTTCCGCAACGAGGAGAGGACGAGGCAGTTC
TGGGTTTCCTACAATGACGGGGACCAGTGCGCCTCCAGCCCCTGCCAGAACGGGGGCTCC
TGTGAGGACCAGCTCCGGTCCTACATCTGCTTCTGCCCCGACGGCTTCGAGGGCCGGAAC
TGTGAGACCGACAAGCAGAGCCAGCTGATCTGCGCCAACGACAATGGCGGCTGTGAGCAG
TACTGTGGGGCTGACCCGGGGGCCGGGCGCTTCTGCTGGTGCCATGAGGGCTACGCGCTC
CAGGCAGACGGGGTGTCCTGCGCACCCACAGTGGAATATCCGTGCGGGAAAATACCTGTT
CTGGAAAAAAGAAATGGCAGCAAGCCCCAAGGGCGAATTGTGGGGGGCCACGTCTGCCCC
AAAGGGGAATGCCCCTGGCAGGCCATGCTGAAGCTGAACGGGGCGCTGCTGTGCGGGGGC
ACCCTGGTCGGCCCGGCCTGGGTGGTCTCCGCCGCCCACTGCTTCGAAAGGCTCCGGAGC
AGGGGGAACCTGACGGCTGTGCTGGGCGAGCACGACCTCAGCCGCGTGGAGGGCCCAGAG
CAGGAGCGGCGGGTGGCGCAGATCATTGTCCCCAAGCAGTACGTGCCGGGCCAGACGGAC
CACGACGTGGCCCTGCTGCAGCTGGCCCAGCCCGTGGCCCTGGGCGACCACGTGGCACCC
CTCTGTCTGCCCGACCCGGACTTCGCGGACCAGACGCTGGCCTTCGTGCGCTTCTCGGCC
GTCAGCGGCTGGGGCCAGCTCCTGGAGCGCGGGGTCACCGCCCGCAAGCTCATGGTGGTG
CTGGTGCCCCGGCTGCTAACCCAGGACTGCCTGCAGCAGTCGCGCCAGAGGCCCGGCGGG
CCTGTGGTCACGGACAACATGTTCTGCGCTGGCTATAGCGACGGCAGCAAGGATGCCTGC
AAGGGGGACAGTGGGGGCCCGCACGCCACACGCTTCCGGGGCACCTGGTTCCTGACCGGC
GTCGTCAGCTGGGGCGAGGGCTGCGCGGCAGCCGGCCACTTTGGGATCTACACGCGGGTC
TCCCGCTACACGGCCTGGCTGCGGCAGCTGATGGGCCACCCGCCGTCCAGGCAGGGCTTC
TTCCAGGTCCCGCTGCTGCCCTAG
Enzyme 33 GenBank Gene ID BT021584 Link Image
Enzyme 33 GeneCard ID F7 Link Image
Enzyme 33 GenAtlas ID Not Available
Enzyme 33 HGNC ID Not Available
Enzyme 33 Chromosome Location Chromosome:1
Enzyme 33 Locus 13q34
Enzyme 33 SNPs SNPJam Report Link Image
Enzyme 33 General References
  1. [PubMed Link Image]
Enzyme 33 Metabolite References Not Available
Enzyme 34 [top]
Enzyme 34 ID 1307
Enzyme 34 Name Arylsulfatase K
Enzyme 34 Synonyms
  1. ASK
Enzyme 34 Gene Name ARSK
Enzyme 34 Protein Sequence >Arylsulfatase K
MLLLWVSVVAASALAAPAPGADGQRRGAIQAWPDAPNVLLVVSDSFDGRLTFYPGSQVVK
LPFINFMKAHGTSFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNFKGLDPNYTTWMDVM
EKHGYRTQKFGKLDYTSGHHSISNRVEAWTRDVAFLLRQEGRPMVNLAPKKTKVRVMQVD
WKNTDRAVNWLRKEASNSTQPFVLYLGLNLPHPYPSPSSGENFGSSTFHTSRYWLKKVSY
DAIKIPKWSPLSEMHPVDYYSSYTKNCTGKFTEKEIKNIRAFYYAMCAETDAMLGEIILA
LRQLGLLQKTIVIYTSDHGELAMEHRQFYKMSMYEASSHVPLLIMGPGIQANLQVSSVVS
LVDIYPTMLDIAGIPLPQNLSGYSLLPSSSEMFKNEQKFKNLHPPWILSEFHGCNVNAST
YMLRTNQWKYIAYSDGASVLPQLFDLSSDPDELTNIAAKFPEVTSSLDQKLRSIINYPKV
SASVHQYNKEQFIKWKQSIGQNYSNVIANLRWHQDWLKKPKKYENAIDQWLKSHSDAKTI
Enzyme 34 Number of Residues 540
Enzyme 34 Molecular Weight 61360.7
Enzyme 34 Theoretical pI 9.40
Enzyme 34 GO Classification
Function
Process
Component
Enzyme 34 General Function Inorganic ion transport and metabolism
Enzyme 34 Specific Function Not Available
Enzyme 34 Pathways Not Available
Enzyme 34 Reactions Not Available
Enzyme 34 Pfam Domain Function
Enzyme 34 Signals
  • 1-22
Enzyme 34 Transmembrane Regions
  • None
Enzyme 34 Essentiality Not Available
Enzyme 34 GenBank ID Protein 109939820 Link Image
Enzyme 34 UniProtKB/Swiss-Prot ID Q148F3 Link Image
Enzyme 34 UniProtKB/Swiss-Prot Entry Name ARSK_BOVIN Link Image
Enzyme 34 PDB ID Not Available
Enzyme 34 Cellular Location Not Available
Enzyme 34 Gene Sequence >1623 bp
ATGCTGCTGCTGTGGGTGTCGGTGGTTGCAGCCTCGGCGCTGGCAGCACCAGCTCCCGGG
GCAGATGGGCAGAGGCGGGGAGCAATTCAGGCTTGGCCCGATGCTCCTAACGTGTTGCTA
GTCGTGAGCGACTCCTTCGATGGAAGGCTAACATTTTATCCAGGAAGTCAGGTAGTGAAA
CTTCCTTTTATCAACTTCATGAAGGCACATGGCACTTCCTTTCTAAATGCCTACACAAAC
TCTCCAATCTGCTGTCCATCGCGTGCAGCAATGTGGAGTGGGCTCTTCACTCACTTAACA
GAATCTTGGAATAACTTTAAGGGCTTAGATCCAAATTATACAACATGGATGGATGTCATG
GAGAAGCATGGCTACAGAACACAAAAATTTGGAAAACTGGACTATACTTCAGGACATCAC
TCCATCAGCAATCGTGTGGAAGCCTGGACAAGAGATGTTGCTTTCTTACTCAGACAGGAA
GGCAGGCCTATGGTTAATCTTGCCCCTAAAAAGACTAAAGTAAGAGTGATGCAAGTGGAC
TGGAAGAATACAGACAGAGCGGTAAACTGGTTACGAAAGGAGGCAAGTAATTCCACTCAA
CCATTTGTTCTGTACTTGGGATTAAATTTACCACACCCGTATCCTTCACCATCTTCAGGA
GAAAATTTTGGATCTTCAACTTTTCACACATCTCGTTATTGGCTTAAAAAGGTGTCGTAT
GATGCCATCAAAATCCCAAAGTGGTCACCTCTGTCAGAAATGCACCCGGTAGATTATTAC
TCTTCATATACCAAAAACTGCACCGGGAAGTTTACAGAAAAGGAAATTAAGAATATTAGA
GCATTTTATTATGCTATGTGTGCTGAGACAGATGCTATGCTTGGTGAAATCATTTTGGCT
CTGCGCCAGTTAGGTCTTCTCCAGAAGACTATCGTCATATACACCTCAGACCATGGGGAG
CTGGCCATGGAACACCGACAGTTTTATAAGATGAGTATGTACGAAGCTAGCTCCCATGTC
CCACTCTTGATCATGGGGCCGGGAATTCAGGCCAACCTACAAGTATCAAGTGTGGTTTCT
CTTGTGGATATTTACCCTACTATGCTCGATATTGCTGGAATTCCTCTGCCTCAGAACCTG
AGCGGATACTCTCTGCTGCCATCATCGTCAGAAATGTTTAAGAATGAACAAAAATTTAAA
AACCTACACCCACCATGGATTCTGAGTGAATTCCATGGATGCAATGTAAATGCTTCCACC
TACATGCTTCGAACTAACCAATGGAAGTATATAGCCTACTCTGATGGTGCTTCAGTATTG
CCTCAACTCTTCGATCTTTCTTCAGATCCAGATGAATTAACAAATATTGCTGCAAAGTTT
CCAGAAGTTACTTCTTCGTTGGATCAGAAGCTTCGTTCCATTATTAACTACCCTAAGGTT
TCTGCTTCTGTCCACCAGTACAATAAAGAGCAGTTTATCAAGTGGAAACAAAGTATAGGG
CAAAACTATTCAAATGTCATAGCAAACCTTAGGTGGCACCAGGACTGGCTGAAAAAACCA
AAGAAGTATGAAAATGCCATCGATCAGTGGCTTAAATCCCACTCTGATGCAAAAACAATT
TAA
Enzyme 34 GenBank Gene ID BC118383 Link Image
Enzyme 34 GeneCard ID ARSK Link Image
Enzyme 34 GenAtlas ID Not Available
Enzyme 34 HGNC ID Not Available
Enzyme 34 Chromosome Location Chromosome:5
Enzyme 34 Locus 5q15
Enzyme 34 SNPs SNPJam Report Link Image
Enzyme 34 General References Not Available
Enzyme 34 Metabolite References Not Available
Enzyme 35 [top]
Enzyme 35 ID 1308
Enzyme 35 Name Calpain-3
Enzyme 35 Synonyms
  1. Calpain L3
  2. Calpain p94
  3. Calcium-activated neutral proteinase 3
  4. CANP 3
  5. Muscle-specific calcium-activated neutral protease 3
  6. New calpain 1
  7. nCL-1
Enzyme 35 Gene Name CAPN3
Enzyme 35 Protein Sequence >Calpain-3
MPTVISASVAPRTGAEPMSPGPIAQAAQDKGTEAGGGNPSGIYSAIISRNFPIIGVKEKT
FEQLHKKCLEKKVLFVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIVGGANRTD
ICQGDLGDCWFLAAIACLTLNKRLLFRVIPHDQSFTENYAGIFHFQFWRYGDWVDVVIDD
CLPTYNNQLVFTKSNHRNEFWNALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFE
IKDAPRDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLKMGELIERMVRNMDNSRLR
DSDLIPEGCSDDRPTRMIVPVQFETRMACGLVKGHAYSVTGLEEALYKGEKVKLVRLRNP
WGQVEWNGSWSDSWKDWSYVDKDEKARLQHQVTEDGEFWMSYDDFIYHFTKLEICNLTAD
ALESDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICS
FLVALMQKNRRKDRKLGANLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSRTYIN
MREVSERFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVKKKKN
KPIIFVSDRANSNKELGVDQETEEGKDNTSPDKQAKSPQLEPGNTDQESEEQRQFRNIFR
QIAGDDMEICADELKNVLNRVVNKHKDLKTQGFTLESCRSMIALMDTDGSGRLNLQEFHH
LWKKIKTWQKIFKHYDTDQSGTINSYEMRNAVKDAGFHLNNQLYDIITMRYADKYMNIDF
DSFICCFVRLEGMFRAFNAFDKDGDGIIKLNVLEWLQLTMYA
Enzyme 35 Number of Residues 822
Enzyme 35 Molecular Weight 94602.4
Enzyme 35 Theoretical pI 5.72
Enzyme 35 GO Classification
Function
Process
Component
Enzyme 35 General Function Involved in calcium ion binding
Enzyme 35 Specific Function Calcium-regulated non-lysosomal thiol-protease
Enzyme 35 Pathways Not Available
Enzyme 35 Reactions Not Available
Enzyme 35 Pfam Domain Function
Enzyme 35 Signals
  • None
Enzyme 35 Transmembrane Regions
  • None
Enzyme 35 Essentiality Not Available
Enzyme 35 GenBank ID Protein 6681711 Link Image
Enzyme 35 UniProtKB/Swiss-Prot ID P51186 Link Image
Enzyme 35 UniProtKB/Swiss-Prot Entry Name CAN3_BOVIN Link Image
Enzyme 35 PDB ID Not Available
Enzyme 35 Cellular Location Not Available
Enzyme 35 Gene Sequence >2469 bp
ATGCCGACCGTCATTAGCGCCTCTGTGGCCCCACGGACAGGGGCTGAGCCCATGTCCCCA
GGGCCCATCGCCCAGGCAGCCCAGGACAAGGGCACCGAGGCAGGGGGTGGAAACCCAAGT
GGCATCTACTCAGCCATCATCAGCCGCAATTTTCCCATTATTGGGGTGAAAGAGAAGACA
TTCGAGCAGCTTCACAAGAAATGTCTGGAAAAGAAGGTTCTTTTTGTGGATCCTGAGTTC
CCACCGGACGAGACCTCCCTGTTTTACAGCCAGAAGTTCCCCATCCAGTTCGTCTGGAAG
AGACCTCCGGAAATTTGTGAGAATCCCCGATTTATCGTTGGTGGAGCCAATAGAACTGAC
ATCTGCCAAGGAGATCTAGGGGACTGCTGGTTTCTTGCAGCCATCGCTTGCCTGACCTTG
AACAAGCGTCTGCTTTTCCGGGTCATACCCCATGATCAGAGTTTCACCGAAAACTACGCG
GGGATTTTTCACTTCCAGTTCTGGCGCTATGGAGACTGGGTGGACGTGGTTATTGATGAC
TGCCTGCCAACCTACAACAATCAACTGGTTTTCACCAAATCCAACCATCGCAATGAGTTC
TGGAATGCTCTGCTGGAGAAGGCTTATGCTAAGCTCCATGGTTCGTATGAAGCCCTGAAA
GGTGGGAACACTACAGAGGCCATGGAGGACTTCACGGGAGGAGTGACAGAGTTTTTTGAA
ATCAAGGATGCTCCCAGAGACATGTACAAGATCATGAAGAAAGCCATCGAGAGGGGTTCC
CTCATGGGCTGCTCCATTGATGATGGCACAAACATGACCTATGGAACCTCTCCTTCTGGG
CTGAAAATGGGGGAGTTGATTGAGCGGATGGTGAGGAATATGGATAACTCGCGGCTCAGG
GACTCAGACCTCATCCCTGAGGGATGCTCAGATGACAGACCAACTCGGATGATTGTTCCA
GTTCAGTTTGAGACAAGAATGGCCTGTGGGCTGGTCAAAGGCCATGCCTACTCAGTCACT
GGGCTGGAGGAGGCCCTGTACAAGGGTGAGAAAGTGAAGCTGGTGCGGCTGCGGAACCCC
TGGGGCCAGGTGGAGTGGAATGGCTCCTGGAGTGACAGCTGGAAGGACTGGAGCTATGTG
GACAAGGACGAGAAGGCCCGTTTGCAGCACCAGGTCACTGAGGATGGAGAGTTCTGGATG
TCCTACGATGATTTTATCTACCATTTCACAAAGCTGGAGATCTGCAACCTCACAGCTGAT
GCCCTGGAGTCCGACAAGCTTCAGACTTGGACAGTGTCCGTGAATGAGGGCCGCTGGGTG
AGGGGCTGCTCTGCCGGAGGCTGCCGCAACTTCCCAGACACTTTCTGGACCAACCCACAG
TACCGTCTGAAGCTCCTAGAGGAGGACGACGACCCCGATGATTCCGAGGTGATCTGTAGT
TTCCTGGTGGCTCTGATGCAGAAGAACCGGAGGAAGGACCGGAAGCTGGGGGCTAACCTC
TTCACCATCGGTTTCGCCATCTACGAGGTTCCCAAAGAGATGCACGGCAACAAGCAGCAC
CTGCAGAAGGACTTCTTCCTGTACAATGCCTCCAAGGCTAGGAGCAGAACCTACATCAAC
ATGCGGGAGGTGTCTGAGCGCTTCCGCCTGCCTCCCAGCGAGTACGTCATTGTGCCCTCC
ACTTACGAGCCCCACCAGGAGGGCGAGTTCATCCTCCGGGTCTTCTCGGAAAAGAGGAAC
CTCTCTGAGGAAGTTGAGAATACAATCTCTGTGGATCGGCCAGTGAAAAAGAAAAAAAAC
AAGCCCATCATCTTTGTTTCAGACCGAGCAAACAGCAACAAGGAGCTGGGTGTGGACCAG
GAAACAGAGGAGGGAAAAGACAACACAAGCCCTGATAAGCAAGCAAAATCCCCACAGCTA
GAGCCTGGCAACACCGACCAGGAAAGTGAGGAACAGCGGCAATTCCGGAATATTTTCAGG
CAGATAGCAGGCGATGACATGGAGATCTGCGCAGATGAGCTCAAGAACGTCCTTAACAGA
GTTGTGAACAAACATAAGGACCTGAAGACACAAGGCTTCACGCTGGAGTCCTGCCGTAGC
ATGATTGCTCTCATGGACACAGATGGCTCTGGAAGACTGAACCTGCAAGAGTTTCATCAC
CTCTGGAAGAAGATTAAGACGTGGCAGAAAATTTTCAAACACTATGACACAGACCAATCT
GGCACCATCAACAGCTACGAGATGCGCAATGCAGTCAAAGATGCAGGCTTCCACCTCAAC
AACCAGCTCTACGATATCATTACCATGCGCTATGCAGACAAGTACATGAATATTGACTTC
GACAGTTTCATCTGCTGCTTTGTCAGGCTGGAGGGCATGTTCAGAGCTTTCAATGCATTT
GACAAGGATGGGGACGGTATCATCAAACTCAATGTTCTCGAGTGGCTGCAGCTCACCATG
TATGCCTGA
Enzyme 35 GenBank Gene ID AF087569 Link Image
Enzyme 35 GeneCard ID CAPN3 Link Image
Enzyme 35 GenAtlas ID Not Available
Enzyme 35 HGNC ID Not Available
Enzyme 35 Chromosome Location Chromosome:1
Enzyme 35 Locus 15q15.1-q21.1
Enzyme 35 SNPs SNPJam Report Link Image
Enzyme 35 General References
  1. [PubMed Link Image]
Enzyme 35 Metabolite References Not Available
Enzyme 36 [top]
Enzyme 36 ID 1309
Enzyme 36 Name Furin
Enzyme 36 Synonyms
  1. Paired basic amino acid residue-cleaving enzyme
  2. PACE
  3. Dibasic-processing enzyme
  4. Trans Golgi network protease furin
Enzyme 36 Gene Name FURIN
Enzyme 36 Protein Sequence >Furin
MELRPWLFWVVAAAGALVLLVADARGEKVFTNTWAVHIPGGPAVADRVARKHGFLNLGQI
FGDYYHFWHRAVTKRSLSPHRLGHNRLQREPQVKWLEQQVAKRRAKRDIYQEPTDPKFPQ
QWYLSGVTQRDLNVKEAWAQGYTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
GLNPNHIHIYSASWGPEDDGKTVDGPAHLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
TESHTGTSAFAPLAAGIIALTLEANKNLTWRDMQHLVVRTSKPAHLNANDWATNGVGRKV
SHSYGYGLLDAGAMVALAQNWTTVAPQRKCTIDILTEPKDIGKRLEVRKTVTACLGEPSH
ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPTPPESIGCKTLTSSQACVVCE
EGFSLHQKNCVQHCPPGFAPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCL
SCPSHASLDPVEQTCSRQSQSSRESHQQQPPPPPRPPPAEVATEPRLRADLLPSHLPEVV
AGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEE
DEGRGERTAFIKDQSAL
Enzyme 36 Number of Residues 797
Enzyme 36 Molecular Weight 87250.1
Enzyme 36 Theoretical pI 6.39
Enzyme 36 GO Classification
Function
Process
Component
Enzyme 36 General Function Posttranslational modification, protein turnover, chaperones
Enzyme 36 Specific Function Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif
Enzyme 36 Pathways Not Available
Enzyme 36 Reactions Not Available
Enzyme 36 Pfam Domain Function
Enzyme 36 Signals
  • 1-24
Enzyme 36 Transmembrane Regions
  • 719-741
Enzyme 36 Essentiality Not Available
Enzyme 36 GenBank ID Protein 439649 Link Image
Enzyme 36 UniProtKB/Swiss-Prot ID Q28193 Link Image
Enzyme 36 UniProtKB/Swiss-Prot Entry Name FURIN_BOVIN Link Image
Enzyme 36 PDB ID 1P8J Link Image
Enzyme 36 PDB File Show
Enzyme 36 3D Structure
Enzyme 36 Cellular Location Not Available
Enzyme 36 Gene Sequence >2394 bp
ATGGAGCTGAGGCCCTGGTTGTTCTGGGTGGTAGCAGCAGCGGGAGCCTTGGTCCTGCTG
GTGGCCGATGCCCGCGGAGAGAAGGTCTTCACCAACACCTGGGCCGTGCACATTCCTGGA
GGCCCAGCCGTCGCTGACCGTGTGGCACGCAAGCATGGCTTCCTCAACCTGGGCCAGATC
TTCGGTGACTATTACCACTTCTGGCATCGAGCGGTGACAAAGCGGTCCCTGTCTCCTCAC
CGCCTGGGCCACAACCGGCTGCAGCGGGAACCTCAAGTTAAGTGGCTGGAGCAGCAGGTG
GCAAAGCGACGGGCCAAACGGGACATATACCAGGAGCCCACGGACCCCAAGTTTCCCCAG
CAGTGGTACCTGTCTGGCGTCACCCAGCGGGACCTGAATGTGAAGGAGGCCTGGGCGCAG
GGCTACACGGGGCGTGGCATTGTGGTCTCTATCCTGGACGACGGCATCGAGAAGAACCAC
CCAGACTTGGCAGGCAATTATGATCCTGGGGCCAGCTTCGATGTCAATGATCAGGACCCT
GACCCCCAGCCCCGGTACACACAGATGAATGACAACAGGCATGGCACACGGTGTGCAGGA
GAGGTGGCTGCGGTGGCCAACAATGGTGTCTGTGGCGTAGGCGTGGCCTACAATGCCCGA
ATTGGAGGGGTGCGCATGCTGGATGGCGAAGTGACAGATGCCGTGGAGGCACGCTCGCTG
GGCCTGAACCCCAACCACATCCACATCTACAGTGCCAGCTGGGGCCCCGAGGACGACGGC
AAGACCGTGGATGGGCCAGCCCACCTGGCTGAGGAGGCCTTCTTCCGGGGGGTCAGCCAG
GGCCGCGGGGGTCTGGGCTCCATCTTTGTCTGGGCCTCGGGGAACGGGGGCCGGGAACAT
GACAGCTGCAATTGCGACGGCTACACCAACAGCATCTACACGCTGTCCATCAGCAGCGCC
ACACAGTTCGGCAACGTGCCCTGGTACAGTGAGGCCTGCTCGTCCACGCTGGCCACCACC
TACAGTAGTGGCAACCAGAATGAGAAGCAGATCGTGACCACTGACCTGCGGCAGAAGTGT
ACAGAGTCTCACACGGGCACCTCTGCGTTCGCCCCACTGGCAGCAGGCATCATCGCTCTC
ACCCTGGAGGCCAATAAGAACCTCACTTGGCGGGACATGCAGCACTTGGTAGTCCGGACC
TCAAAGCCAGCCCACCTCAACGCCAACGACTGGGCCACCAATGGTGTGGGCCGCAAAGTG
AGCCATTCGTACGGCTACGGGCTGTTGGACGCCGGCGCCATGGTGGCTCTGGCCCAGAAC
TGGACGACGGTGGCCCCTCAGCGGAAATGCACCATCGACATCCTCACTGAGCCCAAGGAC
ATCGGGAAGCGGCTGGAGGTGCGGAAGACCGTGACCGCCTGCCTGGGGGAGCCCAGCCAC
ATCACGCGGCTGGAGCATGCTCAGGCACGGCTCACCCTGTCCTACAACCGCCGCGGTGAC
CTTGCCATCCACCTGGTCAGCCCCATGGGCACCCGCTCCACCCTGCTGGCTGCCAGGCCA
CATGACTACTCTGCAGATGGGTTTAACGACTGGGCCTTCATGACGACCCATTCCTGGGAC
GAGGATCCCTCTGGCGAGTGGGTCTTAGAGATTGAAAACACCAGTGAAGCCAACAACTAT
GGGACACTGACCAAGTTCACCCTCGTGCTTTATGGCACGGCCCCTGAGGGTTTGCCCACA
CCCCCTGAGAGCATCGGCTGTAAGACCCTCACTTCCAGTCAGGCCTGTGTGGTGTGCGAG
GAAGGCTTCTCCTTGCACCAGAAGAACTGCGTCCAGCACTGTCCCCCAGGCTTCGCTCCC
CAAGTCCTGGACACACACTACAGCACAGAGAACGACGTGGAGATCATCCGGGCCAGCGTC
TGCACGCCCTGCCACGCCTCGTGCGCCACGTGCCAGGGCCCCGCCCCCACAGACTGCCTC
AGCTGCCCCAGCCACGCCTCCCTGGACCCGGTGGAGCAGACGTGCTCGCGCCAGAGCCAG
AGCAGCCGCGAGTCGCACCAGCAGCAGCCGCCGCCGCCCCCTCGGCCACCGCCCGCGGAG
GTAGCGACGGAGCCGCGGCTGCGGGCGGACCTGCTGCCCTCGCACCTGCCCGAGGTGGTG
GCCGGCCTCAGCTGCGCCTTCATCGTGCTGGTCTTCGTTACCGTCTTCCTGGTCCTGCAG
CTGCGCTCGGGCTTCAGCTTCCGAGGGGTGAAAGTGTACACCATGGACCGCGGCCTCATC
TCCTACAAGGGACTACCCCCTGAAGCCTGGCAGGAGGAGTGCCCGTCCGACTCAGAGGAG
GACGAGGGCCGGGGCGAGAGGACCGCCTTTATCAAAGACCAGAGCGCCCTTTGA
Enzyme 36 GenBank Gene ID X75956 Link Image
Enzyme 36 GeneCard ID FURIN Link Image
Enzyme 36 GenAtlas ID Not Available
Enzyme 36 HGNC ID Not Available
Enzyme 36 Chromosome Location Chromosome:1
Enzyme 36 Locus 15q26.1
Enzyme 36 SNPs SNPJam Report Link Image
Enzyme 36 General References
  1. [PubMed Link Image]
Enzyme 36 Metabolite References Not Available
Enzyme 37 [top]
Enzyme 37 ID 1310
Enzyme 37 Name Coagulation factor IX
Enzyme 37 Synonyms
  1. Christmas factor
  2. Coagulation factor IXa light chain
  3. Coagulation factor IXa heavy chain
  4. Fragment
Enzyme 37 Gene Name F9
Enzyme 37 Protein Sequence >Coagulation factor IX
YNSGKLEEFVRGNLERECKEEKCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGG
MCKDDINSYECWCQAGFEGTNCELDATCSIKNGRCKQFCKRDTDNKVVCSCTDGYRLAED
QKSCEPAVPFPCGRVSVSHISKKLTRAETIFSNTNYENSSEAEIIWDNVTQSNQSFDEFS
RVVGGEDAERGQFPWQVLLHGEIAAFCGGSIVNEKWVVTAAHCIKPGVKITVVAGEHNTE
KPEPTEQKRNVIRAIPYHSYNASINKYSHDIALLELDEPLELNSYVTPICIADRDYTNIF
SKFGYGYVSGWGKVFNRGRSASILQYLKVPLVDRATCLRSTKFSIYSHMFCAGYHEGGKD
SCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
Enzyme 37 Number of Residues 416
Enzyme 37 Molecular Weight 46785.1
Enzyme 37 Theoretical pI 5.38
Enzyme 37 GO Classification
Function
Process
Component
Enzyme 37 General Function Involved in calcium ion binding
Enzyme 37 Specific Function Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa
Enzyme 37 Pathways Not Available
Enzyme 37 Reactions Not Available
Enzyme 37 Pfam Domain Function
Enzyme 37 Signals
  • None
Enzyme 37 Transmembrane Regions
  • None
Enzyme 37 Essentiality Not Available
Enzyme 37 GenBank ID Protein 163054 Link Image
Enzyme 37 UniProtKB/Swiss-Prot ID P00741 Link Image
Enzyme 37 UniProtKB/Swiss-Prot Entry Name FA9_BOVIN Link Image
Enzyme 37 PDB ID 1PFX Link Image
Enzyme 37 PDB File Show
Enzyme 37 3D Structure
Enzyme 37 Cellular Location Not Available
Enzyme 37 Gene Sequence Not Available
Enzyme 37 GenBank Gene ID J00007 Link Image
Enzyme 37 GeneCard ID F9 Link Image
Enzyme 37 GenAtlas ID Not Available
Enzyme 37 HGNC ID Not Available
Enzyme 37 Chromosome Location Not Available
Enzyme 37 Locus Xq27.1-q27.2
Enzyme 37 SNPs SNPJam Report Link Image
Enzyme 37 General References
  1. [PubMed Link Image]
Enzyme 37 Metabolite References Not Available
Enzyme 38 [top]
Enzyme 38 ID 1311
Enzyme 38 Name Guanylyl cyclase-activating protein 2
Enzyme 38 Synonyms
  1. GCAP 2
  2. Guanylate cyclase activator 1B
  3. Retinal guanylyl cyclase activator protein p24
Enzyme 38 Gene Name GUCA1B
Enzyme 38 Protein Sequence >Guanylyl cyclase-activating protein 2
MGQQFSWEEAEENGAVGAADAAQLQEWYKKFLEECPSGTLFMHEFKRFFKVPDNEEATQY
VEAMFRAFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDI
VESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWV
MKMLQMDLNPSSWISQQRRKSAMF
Enzyme 38 Number of Residues 204
Enzyme 38 Molecular Weight 23727.7
Enzyme 38 Theoretical pI 4.47
Enzyme 38 GO Classification
Function
Process
Component
Enzyme 38 General Function Involved in calcium ion binding
Enzyme 38 Specific Function Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure
Enzyme 38 Pathways Not Available
Enzyme 38 Reactions Not Available
Enzyme 38 Pfam Domain Function
Enzyme 38 Signals
  • None
Enzyme 38 Transmembrane Regions
  • None
Enzyme 38 Essentiality Not Available
Enzyme 38 GenBank ID Protein 1002750 Link Image
Enzyme 38 UniProtKB/Swiss-Prot ID P51177 Link Image
Enzyme 38 UniProtKB/Swiss-Prot Entry Name GUC1B_BOVIN Link Image
Enzyme 38 PDB ID 1JBA Link Image
Enzyme 38 PDB File Show
Enzyme 38 3D Structure
Enzyme 38 Cellular Location Not Available
Enzyme 38 Gene Sequence Not Available
Enzyme 38 GenBank Gene ID U32856 Link Image
Enzyme 38 GeneCard ID GUCA1B Link Image
Enzyme 38 GenAtlas ID Not Available
Enzyme 38 HGNC ID Not Available
Enzyme 38 Chromosome Location Chromosome:6
Enzyme 38 Locus 6p21.1
Enzyme 38 SNPs SNPJam Report Link Image
Enzyme 38 General References
  1. [PubMed Link Image]
Enzyme 38 Metabolite References Not Available
Enzyme 39 [top]
Enzyme 39 ID 1312
Enzyme 39 Name Coagulation factor X
Enzyme 39 Synonyms
  1. Stuart factor
  2. Factor X light chain
  3. Factor X heavy chain
  4. Activated factor Xa heavy chain
Enzyme 39 Gene Name F10
Enzyme 39 Protein Sequence >Coagulation factor X
MAGLLHLVLLSTALGGLLRPAGSVFLPRDQAHRVLQRARRANSFLEEVKQGNLERECLEE
ACSLEEAREVFEDAEQTDEFWSKYKDGDQCEGHPCLNQGHCKDGIGDYTCTCAEGFEGKN
CEFSTREICSLDNGGCDQFCREERSEVRCSCAHGYVLGDDSKSCVSTERFPCGKFTQGRS
RRWAIHTSEDALDASELEHYDPADLSPTESSLDLLGLNRTEPSAGEDGSQVVRIVGGRDC
AEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTEQEEGNEM
AHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLMTQKTGIV
SGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDACQGDSGG
PHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKARAGAAGSRGHSEA
PATWTVPPPLPL
Enzyme 39 Number of Residues 492
Enzyme 39 Molecular Weight 54509.6
Enzyme 39 Theoretical pI 5.21
Enzyme 39 GO Classification
Function
Process
Component
Enzyme 39 General Function Involved in calcium ion binding
Enzyme 39 Specific Function Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting
Enzyme 39 Pathways Not Available
Enzyme 39 Reactions Not Available
Enzyme 39 Pfam Domain Function
Enzyme 39 Signals
  • 1-23
Enzyme 39 Transmembrane Regions
  • None
Enzyme 39 Essentiality Not Available
Enzyme 39 GenBank ID Protein 193 Link Image
Enzyme 39 UniProtKB/Swiss-Prot ID P00743 Link Image
Enzyme 39 UniProtKB/Swiss-Prot Entry Name FA10_BOVIN Link Image
Enzyme 39 PDB ID 1KIG Link Image
Enzyme 39 PDB File Show
Enzyme 39 3D Structure
Enzyme 39 Cellular Location Not Available
Enzyme 39 Gene Sequence Not Available
Enzyme 39 GenBank Gene ID X00673 Link Image
Enzyme 39 GeneCard ID F10 Link Image
Enzyme 39 GenAtlas ID Not Available
Enzyme 39 HGNC ID Not Available
Enzyme 39 Chromosome Location Chromosome:1
Enzyme 39 Locus 13q34
Enzyme 39 SNPs SNPJam Report Link Image
Enzyme 39 General References
  1. [PubMed Link Image]
Enzyme 39 Metabolite References Not Available
Enzyme 40 [top]
Enzyme 40 ID 1313
Enzyme 40 Name FK506-binding protein 10
Enzyme 40 Synonyms
  1. Peptidyl-prolyl cis-trans isomerase
  2. PPIase
  3. Rotamase
Enzyme 40 Gene Name FKBP10
Enzyme 40 Protein Sequence >FK506-binding protein 10
MLRAGPPSHTLLRLPLLQLLLLLLVQAVGRGLGRASPAGGPLEDVVIERYHIPRVCPREV
QMGDFVRYHYNGTFEDGKKFDSSYDRHTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIV
PPHLGYGSIGVAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDSDFVRY
HYNGTLLDGTAFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIVIPPFLAYGE
KGYGTVIPSQASLVFHVLLIDVHNPKDTVQLETLELPPGCVRRAVAGDFMRYHYNGSLMD
GTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGSCMGERRRITIPPHLAYGENGTGDKIP
GSAVLIFDVHVIDFHNPADPVEIKTLSRPLETCNETAKLGDFVHYHYNCSLLDGTRLFSS
HDYGAPQEATLGAHKVIEGLDTGLQGMCVGERRQLVVPPHLAHGESGARGVPGSAVLLFE
VELVSREDGLPTGYLFVWHEDPPAHLFEHMDLNKDGEVPVEEFSTFIKAQVSEGKGRLLP
GQDPEKTIGDMFQNQDRNQDGKITAEELKLKSDEDQDRVHEEL
Enzyme 40 Number of Residues 583
Enzyme 40 Molecular Weight 64483.9
Enzyme 40 Theoretical pI 5.82
Enzyme 40 GO Classification
Function
Process
Component
Enzyme 40 General Function Posttranslational modification, protein turnover, chaperones
Enzyme 40 Specific Function PPIases accelerate the folding of proteins during protein synthesis
Enzyme 40 Pathways Not Available
Enzyme 40 Reactions Not Available
Enzyme 40 Pfam Domain Function
Enzyme 40 Signals
  • 1-27
Enzyme 40 Transmembrane Regions
  • None
Enzyme 40 Essentiality Not Available
Enzyme 40 GenBank ID Protein 87578299 Link Image
Enzyme 40 UniProtKB/Swiss-Prot ID Q2HJ89 Link Image
Enzyme 40 UniProtKB/Swiss-Prot Entry Name FKB10_BOVIN Link Image
Enzyme 40 PDB ID Not Available
Enzyme 40 Cellular Location Not Available
Enzyme 40 Gene Sequence >1752 bp
ATGCTCCGCGCGGGCCCCCCCAGCCACACCCTCCTCCGGCTCCCCCTGCTGCAGTTGCTG
CTGCTGCTGCTGGTGCAGGCCGTGGGGAGGGGGCTGGGCCGCGCCAGCCCGGCCGGCGGC
CCCCTGGAAGATGTGGTCATCGAGAGGTACCACATCCCCAGGGTCTGTCCCCGGGAAGTG
CAGATGGGGGATTTTGTGCGCTACCATTACAACGGTACTTTCGAGGACGGCAAGAAATTT
GACTCGAGCTATGACCGCCACACCTTGGTGGCCATCGTGGTAGGCGTGGGGCGCCTCATC
ACTGGCATGGACCGAGGCCTCATGGGCATGTGTGTCAATGAACGACGACGCCTCATTGTG
CCTCCGCACCTAGGCTATGGCAGCATCGGCGTGGCGGGGCTCATCCCCCCCGATGCCACC
CTCTACTTTGACGTGGTCCTGCTGGATGTATGGAACAAGGAGGACACCGTGCAGGTGAGC
ACCTTGCTGCGCCCACCCCACTGCCCTCGGATGGTCCAGGACAGTGACTTTGTGCGCTAC
CACTACAACGGCACGCTGCTGGATGGCACTGCCTTCGACACCAGCTACAGTAAGGGTGGG
ACTTATGACACCTACGTGGGCTCTGGCTGGCTGATCAAGGGCATGGACCAGGGTCTGCTG
GGCATGTGTCCTGGAGAGAGAAGGAAGATCGTCATCCCTCCATTCCTGGCCTATGGCGAG
AAAGGCTATGGGACTGTGATCCCCTCACAGGCCTCGCTGGTCTTCCACGTCCTACTGATT
GACGTCCACAACCCAAAGGACACCGTCCAGCTGGAGACACTTGAGCTGCCGCCTGGCTGC
GTCCGGAGAGCCGTGGCTGGGGACTTCATGCGTTACCACTACAACGGGTCCCTAATGGAT
GGCACTCTCTTTGACTCCAGCTACTCCCGGAACCACACCTACAATACCTATGTGGGGCAG
GGCTACATCATCCCTGGGATGGACCAAGGCCTTCAAGGCTCGTGCATGGGGGAGCGCCGG
AGGATCACCATCCCCCCCCACCTTGCCTACGGGGAGAACGGGACTGGAGACAAGATCCCT
GGCTCTGCTGTGCTGATCTTTGACGTCCACGTGATCGACTTCCACAATCCTGCGGATCCA
GTGGAAATCAAGACACTGTCTCGGCCCCTGGAGACCTGCAACGAGACGGCCAAGCTCGGG
GACTTTGTTCACTACCACTACAACTGCTCTCTGCTGGATGGCACCAGGCTCTTCTCCTCC
CATGACTACGGGGCCCCTCAGGAGGCGACTCTGGGGGCCCACAAAGTGATCGAAGGCCTG
GACACGGGCCTGCAAGGCATGTGCGTGGGAGAGAGGCGGCAGCTCGTGGTCCCCCCGCAC
CTGGCACACGGAGAGAGCGGAGCCCGGGGGGTCCCTGGCAGTGCTGTGCTGCTGTTTGAG
GTGGAGCTAGTGTCTCGGGAGGATGGGCTGCCCACGGGCTACCTGTTTGTGTGGCACGAA
GACCCTCCTGCCCACCTGTTTGAACACATGGACCTTAACAAGGATGGCGAGGTCCCCGTG
GAGGAGTTCTCCACCTTCATCAAGGCTCAAGTCAGTGAGGGCAAAGGCCGCCTCCTGCCT
GGCCAGGATCCTGAGAAAACCATAGGAGACATGTTCCAGAATCAGGATCGCAACCAGGAT
GGCAAGATCACCGCCGAGGAGCTCAAGCTGAAGTCAGATGAAGACCAGGACCGGGTCCAT
GAGGAACTCTGA
Enzyme 40 GenBank Gene ID BC113250 Link Image
Enzyme 40 GeneCard ID FKBP10 Link Image
Enzyme 40 GenAtlas ID Not Available
Enzyme 40 HGNC ID Not Available
Enzyme 40 Chromosome Location Chromosome:1
Enzyme 40 Locus 17q21.2
Enzyme 40 SNPs SNPJam Report Link Image
Enzyme 40 General References Not Available
Enzyme 40 Metabolite References Not Available
Enzyme 41 [top]
Enzyme 41 ID 1314
Enzyme 41 Name Calcineurin subunit B type 1
Enzyme 41 Synonyms
  1. Protein phosphatase 2B regulatory subunit 1
  2. Protein phosphatase 3 regulatory subunit B alpha isoform 1
Enzyme 41 Gene Name PPP3R1
Enzyme 41 Protein Sequence >Calcineurin subunit B type 1
MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVID
IFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMV
GNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV
Enzyme 41 Number of Residues 170
Enzyme 41 Molecular Weight 19299.8
Enzyme 41 Theoretical pI 4.40
Enzyme 41 GO Classification
Function
Process
Component
Enzyme 41 General Function Involved in calcium ion binding
Enzyme 41 Specific Function Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity
Enzyme 41 Pathways Not Available
Enzyme 41 Reactions Not Available
Enzyme 41 Pfam Domain Function
Enzyme 41 Signals
  • None
Enzyme 41 Transmembrane Regions
  • None
Enzyme 41 Essentiality Not Available
Enzyme 41 GenBank ID Protein 312969 Link Image
Enzyme 41 UniProtKB/Swiss-Prot ID P63099 Link Image
Enzyme 41 UniProtKB/Swiss-Prot Entry Name CANB1_BOVIN Link Image
Enzyme 41 PDB ID 1MF8 Link Image
Enzyme 41 PDB File Show
Enzyme 41 3D Structure
Enzyme 41 Cellular Location Not Available
Enzyme 41 Gene Sequence >513 bp
ATGGGAAATGAGGCAAGTTATCCTTTGGAAATGTGCTCACACTTTGATGCAGATGAAATT
AAAAGGCTAGGAAAGAGATTTAAGAAGCTCGATTTGGACAATTCTGGTTCTTTGAGTGTG
GAAGAGTTCATGTCTCTACCTGAGTTACAACAGAATCCCTTAGTACAGCGAGTAATAGAT
ATATTCGACACAGATGGGAATGGAGAAGTAGACTTTAAAGAGTTCATTGAGGGAGTCTCT
CAGTTCAGTGTCAAAGGAGATAAGGAACAGAAGTTGAGGTTTGCTTTCCGTATCTATGAC
ATGGATAAAGACGGCTATATTTCCAATGGGGAACTCTTCCAGGTGCTAAAGATGATGGTG
GGGAACAATCTGAAAGATACACAGTTACAGCAAATTGTAGACAAAACCATAATAAATGCA
GATAAGGATGGGGATGGAAGAATATCCTTTGAAGAATTCTGTGCTGTTGTAGGCGGCCTA
GATATCCACAAAAAGATGGTGGTAGACGTGTGA
Enzyme 41 GenBank Gene ID X71666 Link Image
Enzyme 41 GeneCard ID PPP3R1 Link Image
Enzyme 41 GenAtlas ID Not Available
Enzyme 41 HGNC ID Not Available
Enzyme 41 Chromosome Location Chromosome:2
Enzyme 41 Locus 2p15
Enzyme 41 SNPs SNPJam Report Link Image
Enzyme 41 General References
  1. [PubMed Link Image]
Enzyme 41 Metabolite References Not Available
Enzyme 42 [top]
Enzyme 42 ID 1315
Enzyme 42 Name Chymotrypsin-like elastase family member 1
Enzyme 42 Synonyms
  1. Elastase-1
  2. Elastase I
Enzyme 42 Gene Name CELA1
Enzyme 42 Protein Sequence >Chymotrypsin-like elastase family member 1
MLRLLVFTSLVLYGHSTQDFPETNARVVGGTAVSKNSWPSQISLQYKSGSSWYHTCGGTL
IKQKWVMTAAHCVDSQMTFRVVLGDHNLSQNDGTEQYISVQKIVVHPSWNSNNVAAGYDI
AVLRLAQSATLNSYVQLGVLPQSGTILANNTPCYITGWGRTKTNGQLAQTLQQAYLPSVD
YATCSSSSYWGSTVKTTMVCAGGDGVRAGCQGDSGGPLHCLVNGQYAVHGVTSFVSSLGC
NVSKKPTVFTRVSAYISWINNAIASN
Enzyme 42 Number of Residues 266
Enzyme 42 Molecular Weight 28518.0
Enzyme 42 Theoretical pI 8.71
Enzyme 42 GO Classification
Function
Process
Component
Enzyme 42 General Function Involved in calcium ion binding
Enzyme 42 Specific Function Acts upon elastin
Enzyme 42 Pathways Not Available
Enzyme 42 Reactions Not Available
Enzyme 42 Pfam Domain Function
Enzyme 42 Signals
  • 1-16
Enzyme 42 Transmembrane Regions
  • None
Enzyme 42 Essentiality Not Available
Enzyme 42 GenBank ID Protein 163484 Link Image
Enzyme 42 UniProtKB/Swiss-Prot ID Q28153 Link Image
Enzyme 42 UniProtKB/Swiss-Prot Entry Name CELA1_BOVIN Link Image
Enzyme 42 PDB ID Not Available
Enzyme 42 Cellular Location Not Available
Enzyme 42 Gene Sequence >801 bp
ATGCTGCGCTTGCTGGTGTTCACCTCTCTCGTCCTTTATGGACACAGCACCCAGGACTTT
CCAGAAACCAACGCCCGGGTAGTTGGAGGGACTGCGGTCTCAAAGAATTCTTGGCCCTCT
CAGATTTCCCTCCAGTACAAGTCTGGAAGTTCCTGGTATCACACCTGTGGAGGCACCCTC
ATCAAACAGAAGTGGGTGATGACAGCGGCTCACTGTGTGGATAGCCAAATGACCTTCCGT
GTGGTGCTGGGAGACCACAACCTGAGCCAGAACGATGGCACCGAGCAGTACATCAGCGTG
CAGAAGATCGTGGTGCATCCATCCTGGAACAGCAACAACGTGGCTGCAGGTTACGACATC
GCCGTGCTGCGCCTGGCCCAGAGTGCTACCCTCAACAGCTATGTCCAGCTGGGTGTTCTG
CCACAGTCGGGAACCATCCTGGCTAACAACACGCCCTGCTACATCACAGGCTGGGGCAGG
ACTAAGACCAATGGGCAGCTGGCCCAGACCCTGCAGCAGGCTTACCTGCCCTCCGTGGAC
TACGCCACCTGCTCCAGCTCCTCCTACTGGGGCTCCACTGTGAAGACCACCATGGTGTGC
GCTGGAGGAGACGGAGTTCGTGCTGGATGCCAGGGTGATTCTGGAGGCCCCCTTCACTGC
TTGGTGAATGGCCAGTATGCTGTCCACGGTGTGACCAGCTTTGTATCCAGCCTGGGCTGT
AATGTCTCCAAGAAGCCCACAGTCTTCACCCGGGTCTCTGCTTACATCTCTTGGATAAAT
AATGCCATTGCCAGCAACTGA
Enzyme 42 GenBank Gene ID M80838 Link Image
Enzyme 42 GeneCard ID CELA1 Link Image
Enzyme 42 GenAtlas ID Not Available
Enzyme 42 HGNC ID Not Available
Enzyme 42 Chromosome Location Chromosome:1
Enzyme 42 Locus 12q13
Enzyme 42 SNPs SNPJam Report Link Image
Enzyme 42 General References
  1. [PubMed Link Image]
Enzyme 42 Metabolite References Not Available
Enzyme 43 [top]
Enzyme 43 ID 1316
Enzyme 43 Name Calpain-1 catalytic subunit
Enzyme 43 Synonyms
  1. Calpain-1 large subunit
  2. Calcium-activated neutral proteinase 1
  3. CANP 1
  4. Calpain mu-type
  5. muCANP
  6. Micromolar-calpain
Enzyme 43 Gene Name CAPN1
Enzyme 43 Protein Sequence >Calpain-1 catalytic subunit
MAEEFITPVYCTGVSAQVQKQRAKELGLGRHENAIKYLGQDYEQLRVHCLQRGALFRDEA
FPPVPQSLGFKELGPNSSKTYGIKWKRPTELFSNPQFIVDGATRTDICQGALGDCWLLAA
IASLTLNDTLLHRVVPHGQSFQDGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHS
AQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYNIILK
ALERGSLLGCSIDISSILDMEAVTFKKLVKGHAYSVTGAKQVNYQGQMVNLIRMRNPWGE
VEWTGAWSDGSSEWNGVDPYMREQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS
QRFRNWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEETDDPDPDDYGGRESGCS
FLLALMQKHRRRERRFGRDMETIGFAVYEVPPELMGQPAVHLKRDFFLSNASRARSEQFI
NLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTQELDDQVQANLPDEQVL
SEEEIDENFKSLFRQLAGEDMEISVKELRTILNRIISKHKDLRTTGFSLESCRSMVNLMD
RDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIEFAGFKLNKKLYEL
IITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA
Enzyme 43 Number of Residues 716
Enzyme 43 Molecular Weight 82206.7
Enzyme 43 Theoretical pI 5.26
Enzyme 43 GO Classification
Function
Process
Component
Enzyme 43 General Function Involved in calcium ion binding
Enzyme 43 Specific Function Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction
Enzyme 43 Pathways Not Available
Enzyme 43 Reactions Not Available
Enzyme 43 Pfam Domain Function
Enzyme 43 Signals
  • None
Enzyme 43 Transmembrane Regions
  • None
Enzyme 43 Essentiality Not Available
Enzyme 43 GenBank ID Protein 6942221 Link Image
Enzyme 43 UniProtKB/Swiss-Prot ID Q27970 Link Image
Enzyme 43 UniProtKB/Swiss-Prot Entry Name CAN1_BOVIN Link Image
Enzyme 43 PDB ID Not Available
Enzyme 43 Cellular Location Not Available
Enzyme 43 Gene Sequence >2151 bp
ATGGCCGAGGAGTTCATCACTCCGGTGTACTGCACCGGGGTGTCTGCACAAGTGCAGAAG
CAGCGGGCCAAGGAGCTGGGCCTGGGCCGCCATGAAAATGCCATCAAGTACCTGGGCCAG
GATTACGAGCAGCTGCGGGTTCACTGCCTGCAAAGAGGGGCCCTTTTCCGTGACGAGGCT
TTCCCCCCAGTGCCCCAGAGCCTGGGCTTCAAGGAGCTGGGCCCCAACTCCTCCAAAACC
TATGGCATCAAGTGGAAGCGTCCCACGGAGCTGTTCTCAAACCCCCAGTTCATCGTGGAT
GGAGCCACCCGCACGGACATCTGCCAGGGCGCACTGGGGGACTGTTGGCTCCTGGCTGCC
ATCGCCTCCCTTACCCTCAATGACACCCTCCTGCACCGAGTAGTTCCACATGGCCAAAGC
TTCCAGGATGGCTACGCTGGCATCTTCCATTTCCAGCTGTGGCAGTTTGGTGAGTGGGTG
GATGTGGTGGTGGATGACCTGCTGCCCACCAAGGACGGGAAGCTGGTGTTTGTGCACTCT
GCCCAAGGCAACGAGTTCTGGAGCGCCCTGCTGGAGAAAGCCTATGCCAAGGTGAACGGC
AGCTACGAGGCCCTCTCAGGAGGCAGCACATCTGAGGGCTTTGAGGACTTCACCGGCGGA
GTCACCGAGTGGTACGAGCTGCGCAAGGCGCCCAGCGACCTCTACAACATCATCCTCAAG
GCCCTGGAGCGTGGCTCCCTGCTGGGCTGCTCCATCGATATCTCCAGCATTCTGGACATG
GAGGCTGTCACCTTCAAGAAGCTGGTGAAGGGCCACGCCTACTCTGTGACCGGGGCCAAA
CAGGTGAACTACCAGGGCCAGATGGTGAACCTGATCCGGATGCGGAACCCCTGGGGCGAG
GTGGAGTGGACAGGAGCCTGGAGTGACGGCTCCTCGGAGTGGAACGGCGTGGACCCTTAC
ATGCGGGAGCAGCTCCGGGTCAAGATGGAGGATGGGGAGTTCTGGATGTCATTCCGAGAC
TTCATGCGTGAATTCACCCGCCTGGAGATCTGCAACCTGACACCCGACGCGCTCAAGAGC
CAGAGGTTCCGCAACTGGAACACCACCCTGTATGAGGGCACCTGGCGGCGGGGGAGCACC
GCGGGGGGCTGCCGCAACTACCCAGCCACTTTCTGGGTGAACCCCCAGTTCAAGATCCGG
CTGGAGGAGACGGATGACCCGGACCCCGACGACTACGGGGGTCGCGAGTCAGGCTGCAGC
TTCCTGCTCGCCCTCATGCAGAAGCACCGCCGTCGGGAGCGCCGTTTCGGCCGTGACATG
GAGACCATAGGCTTCGCTGTCTACGAGGTCCCTCCGGAGCTGATGGGCCAGCCGGCCGTG
CATCTGAAGCGGGACTTCTTCCTGTCCAACGCCTCCCGGGCCCGGTCCGAGCAGTTCATC
AACCTGCGGGAGGTCAGCACCCGCTTCCGCCTGCCGCCTGGGGAGTACGTGGTGGTGCCC
TCCACCTTCGAGCCCAACAAGGAAGGTGACTTTGTGCTGCGTTTCTTCTCAGAGAAGAGC
GCAGGGACCCAAGAGCTGGATGACCAGGTCCAGGCCAATCTCCCCGACGAGCAAGTGCTC
TCAGAAGAGGAGATTGATGAGAACTTCAAGTCCCTCTTCAGACAACTGGCAGGGGAGGAC
ATGGAGATCAGCGTCAAGGAGCTGCGGACCATCCTCAACAGGATCATCAGCAAACACAAA
GACCTGCGGACCACGGGCTTCAGCCTGGAGTCCTGCCGCAGCATGGTCAACCTCATGGAT
CGCGACGGCAATGGCAAACTGGGCCTGGTGGAGTTCAACATCCTATGGAACCGGATCCGG
AATTACCTGTCCATCTTCCGGAAGTTTGACCTGGACAAGTCGGGCAGCATGAGTGCCTAT
GAAATGCGGATGGCCATTGAGTTTGCAGGCTTCAAGCTCAACAAGAAGCTGTACGAGCTC
ATTATCACCCGCTACTCGGAGCCCGACCTGGCCGTGGACTTCGACAACTTCGTGTGCTGC
CTGGTGCGGCTGGAGACCATGTTCCGGTTTTTCAAAACTCTGGACACTGATCTGGATGGA
GTGGTGACCTTTGACTTGTTTAAGTGGTTACAGCTGACCATGTTTGCGTGA
Enzyme 43 GenBank Gene ID AF221129 Link Image
Enzyme 43 GeneCard ID CAPN1 Link Image
Enzyme 43 GenAtlas ID Not Available
Enzyme 43 HGNC ID Not Available
Enzyme 43 Chromosome Location Chromosome:1
Enzyme 43 Locus 11q13
Enzyme 43 SNPs SNPJam Report Link Image
Enzyme 43 General References
  1. [PubMed Link Image]
Enzyme 43 Metabolite References Not Available
Enzyme 44 [top]
Enzyme 44 ID 1317
Enzyme 44 Name FK506-binding protein 9
Enzyme 44 Synonyms
  1. Peptidyl-prolyl cis-trans isomerase
  2. PPIase
  3. Rotamase
Enzyme 44 Gene Name FKBP9
Enzyme 44 Protein Sequence >FK506-binding protein 9
MAIRARSWRPPPPPLLLLLLWVTGQAAPVAGLGLGSDSELQIERRFVPEECPRTVRSGDF
VRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQLIAGMDQALVGMCVNERRFVKIPPKLA
YGSDGVSGVIPPDSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGT
FLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGK
DIPGQASLVFDVALLDLHNPKDGISIENKVVPENCERRSQSGDFLRYHYNGTLLDGTFFD
SSYSRNRTFDTYIGQGYVIPGIDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLV
FDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTY
NIVLGFGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLEL
VAGLPEGYMFVWNGEVSANLFEEIDKDGDGEVLLEEFSEYIHAQVASGKGKLAPGFDAEM
IVKNMFTNQDRNGDGKVTAEEFKLKDQETKHDEL
Enzyme 44 Number of Residues 574
Enzyme 44 Molecular Weight 63534.6
Enzyme 44 Theoretical pI 4.70
Enzyme 44 GO Classification
Function
Process
Component
Enzyme 44 General Function Posttranslational modification, protein turnover, chaperones
Enzyme 44 Specific Function PPIases accelerate the folding of proteins during protein synthesis
Enzyme 44 Pathways Not Available
Enzyme 44 Reactions Not Available
Enzyme 44 Pfam Domain Function
Enzyme 44 Signals
  • 1-26
Enzyme 44 Transmembrane Regions
  • None
Enzyme 44 Essentiality Not Available
Enzyme 44 GenBank ID Protein 86821385 Link Image
Enzyme 44 UniProtKB/Swiss-Prot ID Q2KJC8 Link Image
Enzyme 44 UniProtKB/Swiss-Prot Entry Name FKBP9_BOVIN Link Image
Enzyme 44 PDB ID Not Available
Enzyme 44 Cellular Location Not Available
Enzyme 44 Gene Sequence >1725 bp
ATGGCTATCAGGGCCCGGAGTTGGCGGCCCCCGCCGCCGCCGCTGCTCCTGCTGCTTCTC
TGGGTGACCGGGCAGGCGGCCCCTGTGGCGGGCCTGGGACTGGGTTCGGACTCGGAGCTG
CAGATCGAGCGGCGCTTCGTGCCCGAGGAGTGTCCGCGCACCGTGCGCAGCGGCGACTTC
GTGCGCTACCACTACGTGGGGACGTTCCCCGACGGCCAAAAGTTCGACTCCAGCTACGAC
AGAGACTCCACTTTCAACGTGTTCGTGGGAAAAGGACAGCTGATAGCAGGGATGGATCAA
GCTCTGGTTGGGATGTGTGTAAATGAGAGACGGTTTGTGAAGATCCCTCCAAAGCTGGCT
TATGGAAGTGACGGTGTTTCTGGTGTGATCCCCCCAGATTCAGTGCTTCATTTTGATGTA
CTTCTGATGGATATTTGGAATTCGGAAGATCAGGTTCAGATTCACACTTACTTCAAGCCT
CCCAGTTGCCCTCGGACCATCCAGGTATCTGATTTTGTAAGATACCACTACAACGGGACA
TTCCTGGACGGGACACTGTTTGATTCGAGTCACAATCGCATGAAAACATATGACACCTAT
GTGGGAATTGGCTGGCTGATCCCTGGAATGGATAAAGGGCTGTTGGGGATGTGTGTGGGA
GAAAAACGCATCATCACCATTCCTCCTTTTCTGGCCTATGGAGAAGATGGAGACGGGAAA
GACATTCCTGGTCAGGCATCTCTGGTGTTTGATGTTGCGTTATTGGACCTCCATAACCCT
AAGGATGGCATTTCCATTGAGAATAAAGTAGTGCCTGAAAACTGTGAGCGGCGAAGTCAA
AGCGGGGACTTTCTCAGGTATCATTACAACGGCACGCTCCTGGACGGCACATTCTTTGAT
TCCAGCTACTCGCGGAACCGCACTTTTGACACGTACATTGGGCAGGGCTACGTGATTCCT
GGGATTGATGAAGGTTTACTTGGCGTCTGCATCGGAGAGAAGCGGAGGATCGTGGTCCCC
CCTCACCTGGGGTATGGTGAGGAAGGAAGAGGGAACATCCCTGGCTCGGCTGTGCTGGTG
TTTGACATCCACGTGATTGACTTTCACAACCCGTCAGACTCCATCAGCATCACCTCCCAC
TACAAACCCCCTGATTGCTCAGTGCTGAGTAAGAAAGGGGATTACCTCAAGTATCACTAC
AATGCCTCACTTCTGGACGGGACCCTGCTGGATTCCACGTGGAATTTAGGCAAAACGTAT
AACATCGTTTTAGGATTTGGACAGGTCGTGTTGGGAATGGATATGGGTCTCAGAGAGATG
TGCGTTGGAGAGAAGCGGACTGTGATCATTCCGCCCCACCTGGGCTACGGCGAGGCTGGC
GTGGATGGAGAAGTGCCCGGCAGTGCCGTGCTGGTGTTTGACATCGAGCTGCTGGAGCTC
GTGGCTGGCCTGCCAGAGGGGTACATGTTCGTATGGAACGGTGAGGTGTCAGCCAACCTC
TTTGAAGAGATCGACAAGGATGGTGATGGAGAAGTCCTCCTGGAAGAGTTCTCAGAGTAC
ATTCATGCCCAGGTGGCATCTGGAAAAGGGAAACTCGCTCCTGGATTCGATGCTGAGATG
ATCGTGAAGAATATGTTCACCAACCAGGACCGAAATGGAGATGGGAAGGTCACGGCTGAG
GAATTTAAACTCAAAGACCAGGAGACAAAACACGATGAACTCTAA
Enzyme 44 GenBank Gene ID BC105407 Link Image
Enzyme 44 GeneCard ID FKBP9 Link Image
Enzyme 44 GenAtlas ID Not Available
Enzyme 44 HGNC ID Not Available
Enzyme 44 Chromosome Location Chromosome:7
Enzyme 44 Locus 7p11.1
Enzyme 44 SNPs SNPJam Report Link Image
Enzyme 44 General References Not Available
Enzyme 44 Metabolite References Not Available
Enzyme 45 [top]
Enzyme 45 ID 1318
Enzyme 45 Name Annexin A1
Enzyme 45 Synonyms
  1. Annexin-1
  2. Annexin I
  3. Lipocortin I
  4. Calpactin II
  5. Chromobindin-9
  6. p35
  7. Phospholipase A2 inhibitory protein
Enzyme 45 Gene Name ANXA1
Enzyme 45 Protein Sequence >Annexin A1
MAMVSEFLKQAWFIENEEQEYIKTVKGSKGGPGSAVSPYPTFNPSSDVEALHKAITVKGV
DEATIIEILTKRNNAQRQQIKAAYLQEKGKPLDEVLKKALLGHLEEVVLALLKTPAQFDA
EELRAAMKGLGTDEDTLNEILASRTNREIREINRVYREELKRDLAKDIASDTSGDYEKAL
LSLAKGDRSEELAVNDDLADSDARALYEAGERRKGTDVNVFITILTTRSYPHLRRVFQKY
SKYSKHDMNKVLDLELKGDIEKCLTVIVKCATSQPMFFAEKLHQAMKGIGTRHKTLIRIM
VSRSEIDMNDIKACYQKLYGISLCQAILDETKGDYEKILVALCGRD
Enzyme 45 Number of Residues 346
Enzyme 45 Molecular Weight 38951.3
Enzyme 45 Theoretical pI 6.79
Enzyme 45 GO Classification
Function
Process
Component
Enzyme 45 General Function Involved in calcium ion binding
Enzyme 45 Specific Function Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. Binds muscle actin
Enzyme 45 Pathways Not Available
Enzyme 45 Reactions Not Available
Enzyme 45 Pfam Domain Function
Enzyme 45 Signals
  • None
Enzyme 45 Transmembrane Regions
  • None
Enzyme 45 Essentiality Not Available
Enzyme 45 GenBank ID Protein 74 Link Image
Enzyme 45 UniProtKB/Swiss-Prot ID P46193 Link Image
Enzyme 45 UniProtKB/Swiss-Prot Entry Name ANXA1_BOVIN Link Image
Enzyme 45 PDB ID 1MCX Link Image
Enzyme 45 PDB File Show
Enzyme 45 3D Structure
Enzyme 45 Cellular Location Not Available
Enzyme 45 Gene Sequence >1041 bp
ATGGCAATGGTATCTGAATTCCTCAAGCAGGCCTGGTTTATTGAAAATGAAGAGCAGGAA
TACATTAAAACGGTGAAAGGATCCAAAGGTGGTCCTGGGTCAGCAGTGAGCCCCTATCCT
ACGTTCAATCCATCCTCGGATGTTGAGGCCTTGCACAAAGCAATCACAGTTAAAGGTGTG
GATGAAGCAACCATCATTGAAATTCTGACTAAGAGAAACAATGCACAGCGTCAGCAGATC
AAAGCGGCCTATCTGCAGGAGAAAGGAAAGCCCCTGGATGAAGTTCTGAAGAAAGCCCTC
CTCGGTCACCTTGAGGAAGTTGTTTTGGCTCTATTGAAAACTCCAGCCCAGTTTGATGCC
GAAGAGCTCCGTGCTGCCATGAAGGGCCTTGGGACTGATGAAGACACTCTGAATGAAATT
CTGGCATCAAGAACTAACAGAGAGATCAGAGAAATTAACAGAGTCCATAGAGAAGAACTG
AAGAGAGATCTGGCTAAAGACATCGCCTCAGACACATCTGGAGATTATGAGAAGGCTTTG
CTTGCTCTTGCTAAGGGTGACCGATCCGAGGAGCTTGCTGTAAATGACGACTTGGCTGAT
TCAGATGCCAGGGCCTTATATGAAGCAGGAGAAAGAAGAAAAGGGACAGATGTGAATGTG
TTCACTACCATTCTTACCACCAGGAGCTATCCCCATCTCCGCAGAGTGTTTCAGAAATAT
TCCAAGTATAGCAAGCATGACATGAACAAAGTTCTGGACCTGGAGTTGAAAGGTGACATC
GAGAAATGCCTCACAGTTATTGTGAAGTGTGCTACAAGCCAGCCAATGTTCTTTGCTGAG
AAGCTCCATCAGGCCATGAAGGGTATTGGAACTCGTCATAAGACACTGATCAGGATTATG
GTTTCCCGCTCCGAAATTGACATGAATGACATCAAAGCATGCTATCAGAAGTTGTATGGC
ATCTCTCTCTGTCAAGCCATCCTGGATGAAACCAAAGGAGATTATGAAAAAATCCTGGTG
GCTCTCTGTGGAAGAGACTAA
Enzyme 45 GenBank Gene ID X56649 Link Image
Enzyme 45 GeneCard ID ANXA1 Link Image
Enzyme 45 GenAtlas ID Not Available
Enzyme 45 HGNC ID Not Available
Enzyme 45 Chromosome Location Chromosome:9
Enzyme 45 Locus 9q12-q21.2|9q12-q21.2
Enzyme 45 SNPs SNPJam Report Link Image
Enzyme 45 General References
  1. [PubMed Link Image]
Enzyme 45 Metabolite References Not Available
Enzyme 46 [top]
Enzyme 46 ID 1319
Enzyme 46 Name Hepatocyte growth factor-regulated tyrosine kinase substrate
Enzyme 46 Synonyms Not Available
Enzyme 46 Gene Name HGS
Enzyme 46 Protein Sequence >Hepatocyte growth factor-regulated tyrosine kinase substrate
MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVSSIKKKVNDKNPHV
ALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFR
NEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKH
HCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCFEQLNKKAEGKAASTTELPPEYLTS
PLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERMRQKSAYTAYPKAEPTPVASS
APPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPTAQ
PGEGHAIPANVETSLPETDPQAVTAAGAAFSEQYQNGESEESHAQFLKALQNAVTTFVNR
MKSNHVRGRSITNDSAVLSLFQSINTMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARG
ALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKE
RQMRLEQQKQTIQMRAQMPAFSLPYAQLQAMPAAGGVLYQPSGPASFAGTFSPAGSVEGS
PMHTMYMSQPAPAASGPYPSMPAAAADPSMVSAYMYPAGAAGAQAAAQGPAGPTTSPAYS
SYQPTPTQGYQTVASQAPQSLPAISQPPQSGTMGYMGSQSVSMGYQPYSMQNLMPTLPGQ
DAPLPPPQQPYISGQQPVYQQMAPSSGPPQQQPPVAQQPPAQGPPAQGSEAQLISFD
Enzyme 46 Number of Residues 777
Enzyme 46 Molecular Weight 85785.1
Enzyme 46 Theoretical pI 6.10
Enzyme 46 GO Classification
Function
Process
Component
Enzyme 46 General Function Involved in zinc ion binding
Enzyme 46 Specific Function Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down- regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation
Enzyme 46 Pathways Not Available
Enzyme 46 Reactions Not Available
Enzyme 46 Pfam Domain Function
Enzyme 46 Signals
  • None
Enzyme 46 Transmembrane Regions
  • None
Enzyme 46 Essentiality Not Available
Enzyme 46 GenBank ID Protein 110331763 Link Image
Enzyme 46 UniProtKB/Swiss-Prot ID Q0V8S0 Link Image
Enzyme 46 UniProtKB/Swiss-Prot Entry Name HGS_BOVIN Link Image
Enzyme 46 PDB ID Not Available
Enzyme 46 Cellular Location Not Available
Enzyme 46 Gene Sequence >2334 bp
ATGGGGCGTGGCAGTGGCACCTTCGAGCGTCTCCTAGACAAAGCGACCAGCCAGCTTCTT
CTGGAGACTGACTGGGAGTCCATCCTCCAGATCTGTGACCTGATCCGCCAGGGGGACACG
CAGGCAAAATATGCAGTGAGTTCCATCAAGAAGAAAGTTAATGATAAGAATCCCCACGTG
GCCTTGTACGCCCTAGAGGTCATGGAGTCTGTGGTGAAGAATTGCGGCCAGACAGTCCAT
GATGAGGTGGCAAACAAGCAGACCATGGAGGAGCTGAAGGATCTGCTGAAGAGGCAGGTG
GAAGTAAACGTCCGGAACAAGATCCTGTATCTGATTCAGGCCTGGGCACACGCCTTCCGG
AACGAGCCCAAGTACAAGGTGGTCCAGGACACGTACCAGATCATGAAGGTGGAAGGACAC
GTCTTCCCAGAGTTCAAGGAAAGCGATGCCATGTTTGCTGCGGAGAGAGCCCCTGACTGG
GTGGATGCTGAGGAGTGCCACCGGTGCCGGGTGCAGTTTGGGGTCATGACCCGCAAGCAC
CACTGCCGGGCGTGTGGCCAGATCTTCTGCGGCAAGTGCTCTTCCAAGTACTCCACCATC
CCCAAGTTCGGCATTGAGAAGGAGGTGCGGGTGTGTGAGCCCTGCTTTGAGCAGCTCAAC
AAGAAAGCGGAGGGAAAAGCGGCCTCGACGACGGAGCTGCCCCCGGAGTACCTGACCAGC
CCGCTGTCTCAGCAGTCGCAGCTGCCCCCTAAAAGGGATGAGACAGCCCTGCAGGAAGAG
GAGGAGCTGCAGCTGGCCCTGGCCCTGTCTCAGTCGGAGGCCGAGGAGAAGGAACGGATG
AGGCAGAAGTCGGCCTATACCGCGTACCCCAAGGCGGAACCCACGCCCGTGGCCTCCTCA
GCACCCCCCGCCAGCAGCCTGTATTCTTCGCCTGTGAACTCGTCGGCGCCTCTGGCTGAG
GACATCGATCCTGAGCTTGCGCGGTACCTGAACCGGAACTACTGGGAGAAGAAGCAGGAG
GAGGCTCGGAAGAGCCCCACGCCGTCCGCGCCGGTGCCTCTGACAGAGCCCACGGCCCAG
CCTGGGGAGGGACACGCAATCCCTGCCAACGTGGAGACTTCCCTCCCAGAGACAGACCCT
CAGGCCGTAACTGCAGCCGGAGCTGCCTTTAGTGAGCAGTACCAGAATGGGGAGTCCGAG
GAGAGCCACGCACAGTTCCTGAAGGCCCTCCAGAATGCCGTCACCACCTTCGTCAACCGC
ATGAAGAGCAACCACGTGCGGGGCCGCAGCATCACCAACGACTCGGCCGTGCTGTCCCTC
TTCCAGTCCATCAACACCATGCACCCCCAGCTGCTGGAGCTGCTCAACCAGCTGGATGAG
CGCAGGTTATACTACGAGGGACTGCAGGACAAGCTGGCACAGATCCGTGATGCCCGGGGG
GCACTCAGCGCCCTGCGGGAGGAGCACCGGGAGAAGCTTCGCCGCGCAGCTGAGGAGGCT
GAGCGCCAGCGCCAGATCCAGCTGGCCCAGAAGCTGGAGATCATGCGGCAGAAGAAGCAG
GAGTACTTAGAGGTGCAGCGGCAGCTGGCCATCCAGCGCCTGCAGGAGCAGGAGAAGGAG
CGGCAAATGCGCCTGGAGCAGCAGAAGCAGACCATCCAGATGCGGGCCCAGATGCCCGCT
TTCTCCCTGCCCTACGCCCAGCTCCAGGCCATGCCTGCAGCAGGGGGCGTGCTGTACCAG
CCTTCCGGCCCGGCGAGCTTCGCGGGCACCTTCAGCCCGGCCGGCTCGGTGGAGGGCTCG
CCCATGCACACCATGTACATGAGTCAGCCGGCCCCGGCTGCCAGCGGCCCCTACCCCAGC
ATGCCAGCAGCCGCAGCAGACCCCAGCATGGTGAGCGCTTACATGTACCCAGCAGGGGCG
GCTGGTGCACAGGCAGCCGCACAGGGCCCCGCAGGGCCCACCACCAGCCCAGCCTACTCA
TCATACCAGCCTACTCCCACGCAGGGCTATCAGACCGTGGCCTCCCAGGCCCCACAGAGC
CTCCCAGCCATCTCCCAGCCCCCGCAGTCTGGTACGATGGGCTACATGGGGAGCCAGTCA
GTGTCCATGGGCTACCAGCCTTATAGCATGCAGAATCTCATGCCGACCCTCCCCGGCCAA
GACGCGCCTCTGCCGCCCCCACAGCAACCCTATATCTCAGGGCAGCAGCCCGTGTACCAG
CAGATGGCGCCCTCCAGCGGCCCTCCTCAGCAGCAGCCCCCAGTGGCCCAGCAGCCCCCA
GCACAGGGCCCGCCAGCACAGGGCAGTGAAGCCCAGCTCATCTCGTTTGACTGA
Enzyme 46 GenBank Gene ID BT026148 Link Image
Enzyme 46 GeneCard ID HGS Link Image
Enzyme 46 GenAtlas ID Not Available
Enzyme 46 HGNC ID Not Available
Enzyme 46 Chromosome Location Chromosome:1
Enzyme 46 Locus 17q25
Enzyme 46 SNPs SNPJam Report Link Image
Enzyme 46 General References
  1. [PubMed Link Image]
Enzyme 46 Metabolite References Not Available
Enzyme 47 [top]
Enzyme 47 ID 1320
Enzyme 47 Name Calpain-2 catalytic subunit
Enzyme 47 Synonyms
  1. Calpain-2 large subunit
  2. Calcium-activated neutral proteinase 2
  3. CANP 2
  4. Calpain M-type
  5. M-calpain
  6. Millimolar-calpain
Enzyme 47 Gene Name CAPN2
Enzyme 47 Protein Sequence >Calpain-2 catalytic subunit
MAGIAAKLAKDREAAEGLGSHERAVKYLNQDYAALRDECLEAGALFQDPSFPALPSSLGF
KELGPYSSKTRGIEWKRPTEICDNPQFITGGATRTDICQGALGDCWLLAAIASLTLNEEI
LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL
LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKAPPNLFRIIQKALQKGSLLGC
SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESRGSLQKLIRIRNPWGEVEWTGQWNDN
CPNWNTVDPEVRETLTRQHEDGEFWMSFNDFLRHYSRLEICNLTPDTLTSDSYKKWKLTK
MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDQEDGESGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEELTGQTNIHLSKKFFLTTRARERSDTFINLREVLNRFKLPPG
EYIVVPSTFEPNKDGDFCIRVFSEKKADYQVVDDEIEANIDEIDISEDDIDDGFRRLFAQ
LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL
WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDDLIIDFD
NFVRCLIRLETLFRIFKQLDPENTGMIQLDLISWLSFSVL
Enzyme 47 Number of Residues 700
Enzyme 47 Molecular Weight 79934.5
Enzyme 47 Theoretical pI 4.59
Enzyme 47 GO Classification
Function
Process
Component
Enzyme 47 General Function Involved in calcium ion binding
Enzyme 47 Specific Function Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction
Enzyme 47 Pathways Not Available
Enzyme 47 Reactions Not Available
Enzyme 47 Pfam Domain Function
Enzyme 47 Signals
  • None
Enzyme 47 Transmembrane Regions
  • None
Enzyme 47 Essentiality Not Available
Enzyme 47 GenBank ID Protein 134024549 Link Image
Enzyme 47 UniProtKB/Swiss-Prot ID Q27971 Link Image
Enzyme 47 UniProtKB/Swiss-Prot Entry Name CAN2_BOVIN Link Image
Enzyme 47 PDB ID 1KFU Link Image
Enzyme 47 PDB File Show
Enzyme 47 3D Structure
Enzyme 47 Cellular Location Not Available
Enzyme 47 Gene Sequence >2103 bp
ATGGCGGGCATCGCGGCCAAGCTGGCGAAGGACCGGGAGGCGGCCGAGGGGCTGGGCTCG
CACGAGAGGGCGGTCAAGTACCTCAACCAGGACTACGCGGCGCTGCGGGACGAGTGCCTG
GAGGCCGGGGCGCTGTTCCAGGACCCCTCCTTCCCGGCCCTGCCGTCCTCCCTGGGCTTC
AAGGAGTTGGGACCTTACTCCAGCAAGACCCGGGGCATCGAGTGGAAGCGGCCCACGGAG
ATCTGCGATAATCCCCAATTTATTACTGGAGGAGCCACTCGCACAGACATCTGCCAAGGA
GCCCTAGGTGACTGCTGGCTGCTGGCCGCAATTGCCTCCCTCACTTTGAATGAAGAAATC
CTGGCTCGAGTCGTCCCCCTGGACCAGAGCTTCCAGGAGAACTATGCGGGGATCTTCCAC
TTCCAGTTCTGGCAGTACGGCGAGTGGGTGGAGGTGGTGGTGGACGACAGGCTGCCCACC
AAGGACGGGGAGCTGCTCTTCGTGCACTCGGCAGAGGGCAGCGAGTTCTGGAGTGCGCTG
CTGGAGAAGGCCTACGCCAAGATCAATGGGTGTTATGAAGCACTTTCGGGGGGCGCCACC
ACTGAGGGCTTCGAGGACTTCACTGGAGGCATCGCTGAGTGGTATGAGTTGAGGAAGGCC
CCTCCCAACCTGTTCAGGATCATCCAGAAGGCTCTGCAGAAAGGCTCTCTCCTGGGCTGC
TCCATCGATATCACCAGCGCTGCGGACTCGGAGGCCATCACGTTCCAGAAGCTGGTGAAG
GGGCACGCGTACTCGGTGACCGGTGCCGAGGAGGTGGAAAGCAGAGGAAGCCTGCAGAAG
CTGATCCGCATCCGGAATCCCTGGGGAGAGGTGGAGTGGACCGGGCAGTGGAATGACAAC
TGCCCAAACTGGAACACAGTCGACCCCGAGGTGAGGGAAACGCTGACTAGACAGCATGAG
GATGGGGAATTCTGGATGTCTTTCAACGACTTCCTGAGACACTATTCCCGCCTGGAAATC
TGCAACCTGACCCCTGACACACTCACCAGTGACAGCTACAAGAAGTGGAAACTCACCAAG
ATGGATGGGAACTGGAGGCGGGGCTCCACCGCGGGCGGCTGCAGGAACTACCCGAACACG
TTCTGGATGAATCCTCAGTACCTGATCAAGCTGGAGGAAGAGGACGAGGACCAGGAGGAC
GGGGAGAGCGGCTGCACCTTCCTGGTGGGCCTCATCCAGAAGCACCGGCGGCGGCAGAGG
AAGATGGGCGAGGACATGCACACCATTGGCTTCGGCATCTATGAGGTTCCAGAGGAGTTG
ACTGGACAGACCAACATCCACCTCAGCAAAAAATTCTTCCTGACAACCAGAGCGCGGGAG
CGGTCGGACACCTTCATCAACCTGCGGGAGGTGCTCAACCGCTTCAAGCTGCCCCCCGGG
GAGTACATCGTGGTGCCCTCCACCTTCGAGCCCAACAAGGACGGCGACTTCTGCATCCGG
GTCTTTTCCGAGAAGAAAGCCGACTACCAAGTTGTCGACGATGAAATCGAGGCCAACATT
GACGAGATTGACATCAGCGAGGATGACATCGATGATGGATTCAGGAGACTGTTCGCCCAG
CTGGCCGGAGAGGACGCAGAGATTTCTGCCTTTGAGTTGCAGACAATCCTGAGAAGAGTG
CTAGCAAAGCGCCAAGATATCAAGTCCGACGGCTTTAGCATTGAGACCTGCAAAATCATG
GTGGACATGCTCGACTCGGATGGGAGTGGCAAACTGGGTCTGAAGGAGTTCTACATTCTC
TGGACGAAGATTCAGAAATACCAAAAAATTTACCGGGAAATTGATGTGGACCGGTCTGGA
ACCATGAACTCCTATGAGATGCGGAAAGCATTAGAAGAAGCAGGTTTCAAGATGCCCTGT
CAGCTCCACCAAGTGATTGTCGCCCGGTTTGCAGATGACGACCTCATCATCGATTTTGAC
AATTTTGTCCGGTGTTTGATTCGACTGGAGACACTGTTCAGGATATTTAAGCAGCTGGAC
CCCGAGAATACTGGAATGATCCAGCTTGACCTTATCTCTTGGCTGTCTTTTTCAGTACTT
TGA
Enzyme 47 GenBank Gene ID BC134526 Link Image
Enzyme 47 GeneCard ID CAPN2 Link Image
Enzyme 47 GenAtlas ID Not Available
Enzyme 47 HGNC ID Not Available
Enzyme 47 Chromosome Location Chromosome:1
Enzyme 47 Locus 1q41-q42
Enzyme 47 SNPs SNPJam Report Link Image
Enzyme 47 General References Not Available
Enzyme 47 Metabolite References Not Available