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Bovine Rumen Metabolome Database



Showing metabocard for Citrulline (RMDB00904)

Legend: metabolite field enzyme field

Version 1.0
Creation Date 2005-11-16 15:48:42
Update Date 2009-07-07 15:29:55
Accession Number RMDB00904
Common Name Citrulline
Description Citrulline is an amino acid made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from arginine as a by-product of the reaction catalyzed by NOS family (NOS; EC 1.14.13.39). In this reaction arginine is first oxidized into N-hydroxyl-arginine, which is then further oxidized to citrulline concomitant with the release of nitric oxide.; EC 1.14.13.39). Citrulline's name is derived from citrullus, the Latin word for watermelon, from which it was first isolated.
Synonyms
  1. (2S)-2-amino-5-(carbamoylamino)pentanoic acid
  2. (S)-2-Amino-5-ureidopentanoate
  3. (S)-2-Amino-5-ureidopentanoic acid
  4. (S)-2-amino-5-(aminocarbonyl)aminopentanoic acid
  5. 2-Amino-5-uredovalerate
  6. 2-Amino-5-uredovaleric acid
  7. 2-Amino-5-ureidovalerate
  8. 2-Amino-5-ureidovaleric acid
  9. A-amino-d-ureidovalerate
  10. A-amino-d-ureidovaleric acid
  11. Alpha-amino-delta-ureidovalerate
  12. Alpha-amino-delta-ureidovaleric acid
  13. Alpha-amino-gamma-ureidovalerate
  14. Alpha-amino-gamma-ureidovaleric acid
  15. Amino-ureidovalerate
  16. Amino-ureidovaleric acid
  17. CIR
  18. CIT
  19. Cytrulline
  20. D-ureidonorvaline
  21. DL-citrulline
  22. Delta-ureidonorvaline
  23. Gammaureidonorvaline
  24. H-cit-oh
  25. L(+)-2-Amino-5-ureidovalerate
  26. L(+)-2-Amino-5-ureidovaleric acid
  27. L(+)-citrulline
  28. L-2-Amino-5-ureido-valerate
  29. L-2-Amino-5-ureido-valeric acid
  30. L-2-Amino-5-ureidovalerate
  31. L-2-Amino-5-ureidovaleric acid
  32. L-N5-carbamoyl-Ornithine
  33. L-citrulline
  34. L-cytrulline
  35. N()-carbamylornithine
  36. N(5)-(aminocarbonyl)-DL-Ornithine
  37. N(delta)-carbamylornithine
  38. N-carbamylornithine
  39. N5-(Aminocarbonyl)-L-ornithine
  40. N5-(Aminocarbonyl)ornithine
  41. N5-(aminocarbonyl)-Ornithine
  42. N5-Carbamoyl-L-ornithine
  43. N5-carbamoylornithine
  44. N5-carbamylornithine
  45. N5-(aminocarbonyl)ornithine
  46. ND-carbamylornithine
  47. Ndelta-carbamy-ornithine
  48. Ndelta-carbamylornithine
  49. Ngamma-carbamylornithine
  50. Sitrulline
  51. Ureidonorvaline
  52. Ureidovalerate
  53. Ureidovaleric acid
  54. (2S)-2-amino-5-(carbamoylamino)pentanoate
  55. (S)-2-amino-5-(aminocarbonyl)aminopentanoate
Chemical IUPAC Name (2S)-2-amino-5-(carbamoylamino)pentanoic acid
Chemical Formula C6H13N3O3
Chemical Structure Structure
Chemical Taxonomy
Kingdom
  • Organic
Super Class
  • Amino acids and Amino Acid conjugates
Class
  • Amino Acids
Sub Class
  • NA
Family
  • Mammalian_Metabolite
Species
  • primary amine; primary aliphatic amine (alkylamine); carboxylic acid; urea; alpha-aminoacid
Biofunction
  • Component of Alanine and aspartate metabolism; Component of Arginine and proline metabolism
Application
Source
  • Endogenous
Average Molecular Weight 175.186
Monoisotopic Molecular Weight 175.095688
Isomeric SMILES N[C@@H](CCCNC(N)=O)C(O)=O
Canonical SMILES NC(CCCNC(N)=O)C(O)=O
KEGG Compound ID C00327 Link Image
BioCyc ID L-CITRULLINE Link Image
BiGG ID 34627 Link Image
Wikipedia Link Citrulline Link Image
METLIN ID 16 Link Image
PubChem Compound 9750 Link Image
PubChem Substance 11532235 Link Image
ChEBI ID 18211 Link Image
CAS Registry Number 372-75-8
InChI Identifier InChI=1/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1
Synthesis Reference Kakimoto, Toshio; Shibatani, Takeji; Nishimura, Noriyuki; Chibata, Ichiro. Enzymic production of L-citrulline by Pseudomonas putida. Applied Microbiology (1971), 22(6), 992-9.
Melting Point (Experimental) 235.5 oC
Experimental Water Solubility 212 mg/mL [HMP experimental] Source: PhysProp
Predicted Water Solubility 12.8 mg/mL at 25 oC [MEYLAN,WM et al. (1996)]; 21.800001 mg/mL [Predicted by ALOGPS] Calculated using ALOGPS
Physiological Charge 0
State Solid
Experimental LogP/Hydrophobicity -3.19 [SANGSTER (1994)] Source: PhysProp
Predicted LogP/Hydrophobicity -3.27 [Predicted by ALOGPS]; -3.9 [Predicted by PubChem via XLOGP] Calculated using ALOGPS
Material Safety Data Sheet (MSDS)
MOL File Show Link Image
SDF File Show Link Image
PDB File Show Link Image
2D Structure
3D Structure
Experimental PDB ID 1H70 Link Image
Experimental PDB File Show
Experimental PDB Structure
Experimental 1H NMR Spectrum Not Available
Experimental 13C NMR Spectrum Not Available
Experimental 13C HSQC Spectrum Not Available
Predicted 1H NMR Spectrum Show Image
Show Peaklist
Predicted 13C NMR Spectrum Show Image
Show Peaklist
Mass Spectrum
Low Energy
Download File
Show Experimental Conditions Link Image
Medium Energy
Download File
Show Experimental Conditions Link Image
High Energy
Download File
Show Experimental Conditions Link Image
Simplified TOCSY Spectrum Not Available
BMRB Spectrum Not Available
Cellular Location
  • Cytoplasm (Predicted from LogP)
  • mitochondria
Biofluid Location
  • Blood
  • Rumen
Tissue Location
Concentrations (Normal)
Biofluid Rumen
Value 36.8 +/- 20.5 uM
Age N/A
Sex N/A
Condition Normal
Breed Not Available
Experimental Condition Not Available
Comments Not Available
References
  • The rumen metabolome (in preparation)
Concentrations (Abnormal) Not Available
Pathway Names Not Available
HMDB Pathways Not Available
KEGG Pathways Not Available
SimCell Pathways Not Available
General References
  1. Wikipedia Link Image
Metabolic Enzymes
  1. Nitric oxide synthase, endothelial
  2. Nitric oxide synthase, inducible
  3. Argininosuccinate synthase
  4. N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
  5. N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
  6. Ornithine carbamoyltransferase, mitochondrial
Enzyme 1 [top]
Enzyme 1 ID 22
Enzyme 1 Name Nitric oxide synthase, endothelial
Enzyme 1 Synonyms
  1. Endothelial NOS
  2. eNOS
  3. EC-NOS
  4. NOS type III
  5. NOSIII
  6. Constitutive NOS
  7. cNOS
Enzyme 1 Gene Name NOS3
Enzyme 1 Protein Sequence >Nitric oxide synthase, endothelial
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSRAPAPATPHAPDHSPAPNSPT
LTRPPEGPKFPRVKNWELGSITYDTLCAQSQQDGPCTPRCCLGSLVLPRKLQTRPSPGPP
PAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAW
RNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGR
GDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDE
APELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFSAAPFSGWYM
STEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIV
DHHAATVSFMKHLDNEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYILSPAFRYQPD
PWKGSATKGAGITRKKTFKEVANAVKISASLMGTLMAKRVKATILYASETGRAQSYAQQL
GRLFRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYN
SSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP
HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAKAAFQASCETFCVGEEAKA
AAQDIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRAT
ILVRLDTAGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPTESVAVEQLEKGSPG
GPPPSWVRDPRLPPCTLRQALTFFLDITSPPSPRLLRLLSTLAEEPSEQQELETLSQDPR
RYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPNAHPGEVHLTVA
VLAYRTQDGLGPLHYGVCSTWLSQLKTGDPVPCFIRGAPSFRLPPDPYVPCILVGPGTGI
APFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQERGVFGRVLTAFS
REPDSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDME
LDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGP
DTPGP
Enzyme 1 Number of Residues 1205
Enzyme 1 Molecular Weight 133285.5
Enzyme 1 Theoretical pI 6.92
Enzyme 1 GO Classification
Function
Process
Component
Enzyme 1 General Function Inorganic ion transport and metabolism
Enzyme 1 Specific Function Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets
Enzyme 1 Pathways Not Available
Enzyme 1 Reactions Not Available
Enzyme 1 Pfam Domain Function
Enzyme 1 Signals
  • None
Enzyme 1 Transmembrane Regions
  • None
Enzyme 1 Essentiality Not Available
Enzyme 1 GenBank ID Protein 163422 Link Image
Enzyme 1 UniProtKB/Swiss-Prot ID P29473 Link Image
Enzyme 1 UniProtKB/Swiss-Prot Entry Name NOS3_BOVIN Link Image
Enzyme 1 PDB ID 1FOL Link Image
Enzyme 1 PDB File Show
Enzyme 1 3D Structure
Enzyme 1 Cellular Location Not Available
Enzyme 1 Gene Sequence >3618 bp
ATGGGCAACTTGAAGAGTGTGGGCCAGGAGCCCGGGCCCCCCTGCGGCCTGGGGCTGGGG
CTGGGCCTCGGGCTATGCGGCAAGCAGGGCCCAGCCTCCCCGGCACCTGAGCCCAGCCGG
GCCCCCGCACCCGCCACCCCGCACGCGCCAGACCACAGCCCAGCTCCCAACAGCCCCACG
CTGACCCGGCCTCCGGAGGGGCCCAAGTTCCCTCGCGTGAAGAACTGGGAGCTGGGGAGC
ATCACCTACGACACTCTGTGCGCGCAGTCCCAACAGGACGGGCCCTGCACTCCCAGGTGC
TGCCTGGGCTCCCTGGTGTTGCCCCGGAAACTGCAGACCCGGCCCTCCCCGGGACCTCCA
CCCGCTGAGCAGCTGCTGAGCCAGGCCAGGGACTTCATCAACCAGTACTACAGCTCCATC
AAGAGGAGCGGCTCCCAGGCTCACGAGGAGCGGCTTCAGGAGGTGGAGGCCGAGGTGGCA
TCCACGGGCACCTACCACCTCCGAGAGAGCGAGCTGGTGTTCGGGGCCAAGCAGGCCTGG
CGCAACGCACCCCGCTGCGTGGGCCGCATCCAGTGGGGGAAGCTGCAGGTGTTTGATGCC
CGGGACTGCAGCTCAGCACAGGAGATGTTCACCTACATCTGCAACCACATCAAGTACGCC
ACCAACCGCGGCAACCTTCGCTCGGCCATCACAGTGTTCCCGCAGCGCGCCCCGGGCCGC
GGAGACTTCCGGATCTGGAACAGCCAGCTGGTGCGCTACGCAGGCTACAGACAGCAGGAT
GGCTCTGTGCGTGGGGACCCAGCCAATGTGGAGATCACGGAGCTCTGCATCCAGCACGGC
TGGACCCCCGGAAACGGCCGCTTCGACGTGCTGCCCCTGCTGCTCCAGGCCCCAGACGAG
GCTCCAGAGCTCTTTGTTCTGCCCCCCGAGCTGGTCCTTGAAGTGCCCCTGGAGCACCCC
ACACTGGAGTGGTTCGCGGCCCTGGGCCTGCGATGGTATGCCCTCCCGGCCGTGTCCAAC
ATGCTGCTGGAAATCGGGGGTCTGGAGTTCTCCGCGGCCCCCTTCAGCGGCTGGTACATG
AGCACGGAGATTGGCACGCGGAACCTGTGTGACCCTCACCGCTACAATATCCTGGAGGAT
GTGGCCGTCTGCATGGACCTCGACACGCGGACCACCTCGTCCCTGTGGAAGGACAAGGCG
GCCGTGGAGATCAACCTGGCTGTGCTGCACAGCTTTCAGCTCGCCAAGGTGACCATCGTG
GACCACCACGCCGCCACGGTGTCCTTCATGAAGCACCTGGACAACGAGCAGAAGGCCAGG
GGGGGCTGCCCCGCCGACTGGGCCTGGATCGTGCCCCCCATCTCAGGCAGCCTCACGCCC
GTCTTCCACCAGGAGATGGTCAACTACATCCTGTCCCCTGCCTTCCGCTACCAGCCAGAC
CCCTGGAAAGGGAGCGCGACCAAGGGCGCAGGCATCACCAGGAAGAAGACCTTTAAGGAA
GTGGCCAACGCGGTGAAGATCTCTGCCTCACTCATGGGCACCCTGATGGCCAAGCGAGTG
AAAGCAACCATCCTGTACGCCTCTGAGACCGGCCGGGCCCAGAGCTACGCTCAGCAGCTG
GGGAGGCTCTTCCGGAAGGCCTTCGATCCCCGGGTCCTGTGCATGGATGAGTATGACGTG
GTGTCCCTGGAGCACGAGGCGCTGGTACTGGTGGTGACCAGCACCTTTGGGAATGGCGAT
CCCCCGGAGAATGGAGAGAGTTTTGCAGCTGCCCTGATGGAGATGTCGGGGCCCTACAAC
AGCTCCCCGCGGCCGGAACAGCACAAGAGTTACAAGATCCGCTTCAACAGCGTCTCCTGC
TCAGACCCGCTGGTGTCCTCCTGGCGGCGGAAGAGAAAGGAGTCCAGCAACACAGACAGT
GCGGGGGCCCTGGGGACCCTCAGGTTCTGTGTGTTCGGACTGGGCTCCCGGGCATACCCC
CACTTCTGCGCCTTCGCGCGAGCGGTGGACACCCGGCTGGAAGAGCTTGGAGGGGAGCGG
CTGCTGCAGCTGGGCCAGGGCGATGAGCTCTGCGGCCAGGAAGAGGCCTTCCGTGGTTGG
GCAAAGGCGGCCTTCCAGGCCTCCTGTGAGACCTTCTGCGTTGGGGAGGAGGCCAAGGCC
GCCGCCCAGGACATCTTCAGCCCCAAACGGAGCTGGAAACGCCAGAGGTACCGGCTGAGC
ACCCAGGCCGAGGGCCTCCAGCTGCTGCCAGGCCTGATCCACGTGCACAGACGGAAGATG
TTTCAGGCCACAGTCCTCTCGGTGGAAAATCTGCAAAGCAGCAAGTCCACCCGGGCCACC
ATCCTGGTGCGCCTGGACACTGCAGGCCAGGAGGGGCTGCAGTACCAGCCGGGGGACCAC
ATAGGCATCTGCCCGCCCAACCGGCCGGGCCTGGTGGAGGCGCTGCTGAGCCGCGTGGAG
GACCCGCCACCGCCCACCGAGTCTGTGGCTGTGGAGCAGCTGGAGAAAGGCAGCCCAGGC
GGCCCTCCTCCCAGCTGGGTGCGGGACCCACGGCTGCCCCCGTGCACGCTGCGCCAGGCT
CTCACCTTCTTCCTGGACATCACCTCCCCACCCAGCCCCCGGCTTCTCCGACTGCTCAGC
ACCCTGGCCGAAGAACCCAGCGAGCAGCAGGAGCTTGAGACCCTCAGTCAGGACCCCCGG
CGCTACGAGGAGTGGAAGTGGTTCCGCTGCCCCACGCTGCTGGAGGTGCTGGAGCAGTTC
CCGTCCGTGGCGCTGCCCGCCCCGCTGCTCCTCACCCAGCTGCCCCTGCTGCAGCCCCGG
TACTACTCTGTCAGCTCGGCCCCCAACGCCCACCCCGGAGAGGTCCACCTCACAGTGGCC
GTGCTGGCGTACAGGACCCAAGATGGGCTGGGCCCCCTACACTACGGGGTCTGCTCCACA
TGGCTGAGCCAGCTCAAGACTGGAGACCCCGTGCCCTGCTTCATCAGGGGGGCTCCCTCC
TTCCGGCTGCCGCCTGACCCCTACGTGCCCTGCATCCTCGTGGGCCCTGGCACTGGCATC
GCCCCCTTCCGGGGATTTTGGCAGGAGAGGCTGCATGACATTGAGAGCAAAGGGCTGCAG
CCCGCCCCCATGACCCTGGTGTTCGGCTGCCGCTGCTCCCAACTCGACCATCTCTACCGC
GACGAGGTGCAGGACGCCCAGGAGCGCGGGGTGTTTGGCCGCGTCCTCACCGCCTTCTCC
CGGGAACCTGACAGCCCCAAGACCTACGTACAGGACATCCTGAGAACCGAGCTGGCTGCC
GAGGTGCACCGCGTGCTGTGCCTCGAGCGGGGCCACATGTTTGTCTGCGGCGATGTCACT
ATGGCAACCAGCGTCCTGCAGACGGTGCAGCGCATCTTGGCGACAGAGGGCGACATGGAG
CTGGACGAGGCGGGCGACGTCATCGGCGTGCTGCGGGATCAGCAACGCTATCACGAGGAC
ATTTTCGGCCTCACGCTGCGCACCCAGGAGGTGACAAGCCGTATACGTACCCAGAGCTTT
TCCCTGCAGGAGCGGCATCTGCGGGGCGCGGTGCCCTGGGCCTTCGACCCGCCCGGCCCA
GACACCCCCGGCCCCTGA
Enzyme 1 GenBank Gene ID M99057 Link Image
Enzyme 1 GeneCard ID NOS3 Link Image
Enzyme 1 GenAtlas ID Not Available
Enzyme 1 HGNC ID Not Available
Enzyme 1 Chromosome Location Chromosome:7
Enzyme 1 Locus 7q36
Enzyme 1 SNPs SNPJam Report Link Image
Enzyme 1 General References
  1. [PubMed Link Image]
Enzyme 1 Metabolite References Not Available
Enzyme 2 [top]
Enzyme 2 ID 69
Enzyme 2 Name Nitric oxide synthase, inducible
Enzyme 2 Synonyms
  1. Inducible NO synthase
  2. Inducible NOS
  3. iNOS
  4. NOS type II
  5. NOSII
Enzyme 2 Gene Name NOS2
Enzyme 2 Protein Sequence >Nitric oxide synthase, inducible
MACPWQFLFKIKSQKVDLATELDINNNVGKFYQPPSSPVTQDDPKRHSPGKHGNESPQPL
TGTVKTSPESLSKLDAPPSACPRHVRIKNWGSGVTFQDTLHQKAKGDLSCKSKSCLASIM
NPKSLTIGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ
LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYATNNGNI
RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG
RFDVLPLVLQADGRDPELFEIPPDLVLEVPMEHPRYEWFRELELKWYALPAVANMLLEVG
GLEFPGCPFNGWYMGTEVGVRDFCDAQRYNILEEVGRRMGLETHKVASLWKDRAVVEINV
AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM
LNYVLSPFYYYQVEPWKTHVWQDERRRPQRREIRFKVLVKAVFFASVLMHKAMASRVRAT
ILFATETGRSETLAQDLGALFSCAFNPKVLCMDQYQLSHLEEEQLLLVVTSTFGNGDSPG
NGEKLKKSLLMLKELTNTFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQLAPTGEGD
ELSGQEEAFRSWAVQTFKAACETFDVSGKHHIEIPKLYTSNVTWDPQHYRLVQDSEPLDL
NKALSSMHAKHVFTMRLKSQQNLQSPKSSRTTLLVELSCEGSQAPSYLPGEHLGVFPCNQ
PALVQGILERVVDGPAPHQPVRLETLCENGSYWVKDKRLPPCSLSQALTYFLDITTPPTQ
LLLRKLAQLATEEAEKQRLETLCQPSDYNKWKFTNSPTFLEVLEEFPSLRVSASFLLSQL
PILKPRYYSISSSRDLTPTEIHLTVAVLTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCF
VRSASGFQLPEDRSRPCILIGPGTGIAPFRSFWQQRLHEAEHKGLQGGRMTLVFGCRRPE
EDHLYWEEMLEMARKGVLHEVHTAYSRLPDQPKVYVQDILRQRLAGEVLRVLHEEQGHLY
VCGDVRMARDVARTLKQLMATALSLNEEQVEDYFFQLKNQKRYHEDIFGAVFPYEVKKDG
AAGLPSNPRAPGAHRS
Enzyme 2 Number of Residues 1156
Enzyme 2 Molecular Weight 131206.8
Enzyme 2 Theoretical pI 7.42
Enzyme 2 GO Classification
Function
Process
Component
Enzyme 2 General Function Inorganic ion transport and metabolism
Enzyme 2 Specific Function Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions
Enzyme 2 Pathways Not Available
Enzyme 2 Reactions Not Available
Enzyme 2 Pfam Domain Function
Enzyme 2 Signals
  • None
Enzyme 2 Transmembrane Regions
  • None
Enzyme 2 Essentiality Not Available
Enzyme 2 GenBank ID Protein 110468061 Link Image
Enzyme 2 UniProtKB/Swiss-Prot ID Q27995 Link Image
Enzyme 2 UniProtKB/Swiss-Prot Entry Name NOS2_BOVIN Link Image
Enzyme 2 PDB ID 2NSI Link Image
Enzyme 2 PDB File Show
Enzyme 2 3D Structure
Enzyme 2 Cellular Location Not Available
Enzyme 2 Gene Sequence >3471 bp
ATGGCCTGTCCCTGGCAGTTTCTGTTCAAAATCAAATCCCAAAAGGTGGACTTGGCTACG
GAACTGGACATCAACAACAATGTGGGAAAATTCTACCAGCCCCCGTCCAGTCCAGTGACA
CAGGATGACCCCAAACGTCACAGCCCGGGCAAGCACGGGAATGAGTCTCCCCAGCCCCTC
ACGGGGACAGTAAAGACGTCTCCAGAATCCCTGAGCAAGCTGGACGCGCCCCCGTCAGCC
TGTCCACGGCATGTGAGGATCAAAAACTGGGGCAGCGGAGTGACTTTCCAAGACACGCTT
CACCAGAAGGCCAAAGGGGATCTCTCTTGCAAGTCCAAGTCTTGCCTGGCATCCATCATG
AACCCCAAAAGTTTGACCATAGGACCCCGGGACAAGCCAACCCCCCCAGACGAGCTTCTA
CCTCAAGCTATCGAATTTGTCAACCAGTATTACGGCTCCTTCAAAGAGGCAAAAATAGAG
GAACATCTGGCCAGGGTGGAAGCAGTAACAAAGGAGATAGAAACAACAGGAACCTACCAG
CTGACGGGAGATGAGCTCATCTTCGCCACCAAGCAGGCCTGGCGCAACGCCCCCCGCTGC
ATCGGAAGGATCCAGTGGTCGAACCTGCAGGTCTTTGACGCCCGGAGCTGTTCCACGGCC
CAGGAAATGTTCGAACACATCTGCAGACACGTGCGTTATGCCACCAACAACGGCAACATC
AGGTCGGCCATCACTGTGTTCCCCCAGCGGAGCGATGGGAAGCATGACTTCCGGGTCTGG
AACGCCCAGCTCATCCGCTATGCCGGCTACCAGATGCCAGATGGCAGCATCAGAGGGGAC
CCCGCCAACGTGGAGTTCACACAGCTGTGCATCGACCTGGGCTGGAAGCCCAAGTACGGC
CGCTTCGACGTGTTGCCTCTAGTCCTGCAGGCTGACGGCCGTGACCCAGAGCTCTTCGAA
ATCCCCCCTGACCTTGTTCTCGAGGTGCCCATGGAACATCCCAGGTACGAATGGTTCCGG
GAGCTGGAGCTCAAGTGGTACGCCCTGCCAGCCGTGGCCAACATGCTGCTTGAGGTGGGC
GGCCTCGAGTTCCCAGGGTGCCCCTTCAACGGGTGGTACATGGGCACAGAAGTTGGAGTC
CGGGACTTCTGCGACGCCCAGCGATACAACATCCTGGAGGAAGTGGGCAGAAGGATGGGC
CTGGAAACGCACAAGGTGGCCTCACTCTGGAAGGACCGGGCTGTCGTTGAGATCAACGTC
GCTGTGCTCCACAGTTTCCAGAAGCAGAACGTGACCATCATGGACCACCACTCCGCTGCA
GAGTCCTTCATGAAGTACATGCAGAATGAGTACCGCTCCCGAGGGGGCTGCCCAGCTGAC
TGGATTTGGCTGGTCCCCCCGATCTCTGGAAGCATCACCCCCGTGTTCCACCAGGAGATG
TTAAATTACGTCCTGTCCCCTTTCTACTACTACCAGGTGGAGCCCTGGAAAACCCACGTC
TGGCAGGACGAGAGGCGGAGACCCCAGAGAAGAGAAATTCGATTCAAAGTCTTGGTCAAA
GCCGTGTTCTTCGCCTCGGTGCTGATGCATAAGGCCATGGCATCCCGGGTCAGAGCCACG
ATCCTCTTTGCAACAGAGACGGGGAGATCGGAAACGCTGGCCCAGGACCTGGGGGCTTTG
TTCAGCTGTGCCTTCAACCCCAAGGTTCTCTGCATGGATCAGTACCAGCTGAGCCATCTG
GAGGAGGARCAGCTGCTGCTGGTGGTGACCAGCACTTTTGGCAACGGAGACTCCCCTGGC
AACGGAGAGAAACTGAAGAAGTCCCTCTTGATGCTGAAAGAACTCACCAACACGTTCCGG
TACGCCGTGTTTGGCCTTGGCTCCAGCATGTACCCTCAGTTCTGCGCTTTTGCTCATGAC
ATTGACCAGAAGTTGTCCCAGCTGGGGGCTTCTCAGCTTGCCCCAACCGGGGAAGGGGAC
GAACTCAGCGGGCAGGAGGAGGCCTTTCGCAGCTGGGCCGTGCAAACCTTCAAGGCAGCC
TGTGAGACATTCGATGTCAGCGGCAAGCACCACATTGAGATCCCCAAGCTCTACACTTCC
AATGTGACCTGGGACCCGCAGCACTACAGGCTCGTGCAGGACTCAGAGCCTCTGGACCTC
AACAAAGCCCTGAGCAGTATGCACGCCAAGCATGTGTTCACCATGAGGCTCAAATCGCAG
CAGAATCTGCAGAGTCCGAAATCCAGCCGCACCACCCTCCTGGTGGAACTCTCCTGTGAG
GGCAGCCAAGCTCCAAGCTACCTGCCGGGAGAGCACCTCGGAGTTTTCCCATGCAACCAG
CCGGCCCTGGTTCAAGGCATCCTTGAGCGAGTGGTGGATGGCCCTGCCCCGCACCAGCCT
GTGCGCCTGGAGACCCTCTGTGAGAATGGCAGCTATTGGGTCAAGGATAAGCGGCTGCCA
CCTTGCTCACTCAGCCAGGCTCTCACCTATTTCCTGGACATCACCACCCCGCCAACCCAG
CTGCTGCTCCGAAAGCTGGCCCAGCTGGCCACAGAAGAGGCTGAGAAGCAGAGGCTGGAG
ACCCTATGCCAGCCCTCAGATTACAACAAGTGGAAGTTCACCAACAGCCCCACATTTCTG
GAGGTGCTGGAGGAGTTCCCGTCCCTGCGGGTGTCTGCCAGCTTCCTGCTCTCCCAGCTC
CCTATTCTGAAGCCCCGGTACTACTCCATCAGCTCCTCCAGGGACCTCACACCCACGGAG
ATCCACCTCACTGTGGCCGTGCTCACGTACCGCACCCGAGATGGCCAAGGTCCCCTGCAC
CATGGTGTCTGCAGCACGTGGCTCAGCAGCTTGAAGCCCCAAGACCCGGTGCCCTGCTTT
GTGCGAAGTGCCAGYGGCTTCCAGCTTCCCGAGGACCGCTCCCGTCCTTGCATCCTCATT
GGGCCCGGCACGGGCATCGCCCCCTTCCGCAGTTTCTGGCAGCAGCGGCTCCATGAGGCT
GAGCACAAAGGGCTCCAGGGCGGCCGCATGACCCTGGTTTTCGGGTGCCGCCGCCCAGAA
GAGGACCACCTCTACTGGGAGGAGATGCTGGAGATGGCCCGCAAGGGGGTGCTGCACGAG
GTGCACACCGCCTATTCCCGCCTGCCTGACCAGCCCAAGGTCTATGTTCAAGACATCCTG
CGGCAGCGGCTGGCGGGCGAGGTGCTTCGCGTGCTCCATGAGGAGCAAGGTCACCTCTAT
GTCTGTGGGGATGTGCGCATGGCCCGGGACGTGGCCCGCACCCTGAAGCAGCTGATGGCT
ACTGCGCTGAGCCTGAACGAGGAACAGGTGGAGGACTATTTCTTCCAGCTCAAGAACCAG
AAGCGCTATCATGAAGACATCTTTGGTGCTGTATTTCCCTATGAGGTGAAAAAGGATGGG
GCAGCAGGGCTGCCCAGCAATCCCAGAGCTCCAGGCGCCCACAGAAGTTAA
Enzyme 2 GenBank Gene ID DQ676956 Link Image
Enzyme 2 GeneCard ID NOS2 Link Image
Enzyme 2 GenAtlas ID Not Available
Enzyme 2 HGNC ID Not Available
Enzyme 2 Chromosome Location Chromosome:1
Enzyme 2 Locus 17q11.2-q12
Enzyme 2 SNPs SNPJam Report Link Image
Enzyme 2 General References
  1. [PubMed Link Image]
Enzyme 2 Metabolite References Not Available
Enzyme 3 [top]
Enzyme 3 ID 237
Enzyme 3 Name Argininosuccinate synthase
Enzyme 3 Synonyms
  1. Citrulline--aspartate ligase
Enzyme 3 Gene Name ASS1
Enzyme 3 Protein Sequence >Argininosuccinate synthase
MSGKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF
IEDISKEFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG
KGNDQIRFELTCYSLAPQIKVIAPWRMPEFYNRFQGRNDLMEYAKQHGIPVPVTPKNPWS
MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNSPDMLEIEFKKGVPVKVTNVGD
GTTHSTALELFLYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF
TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVFKGQVYI
LGRESPLSLYNEELVSMNVQGDYEPVDATGFININSLRLKEYHRLQNKVTAK
Enzyme 3 Number of Residues 412
Enzyme 3 Molecular Weight 46416.9
Enzyme 3 Theoretical pI 7.61
Enzyme 3 GO Classification
Function
Process
Component
Enzyme 3 General Function Nucleotide transport and metabolism
Enzyme 3 Specific Function ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate
Enzyme 3 Pathways
  • Nitrogen metabolism
  • urea cycle
  • (N(omega)-L- arginino)succinate from L-aspartate and L-citrulline:step 1/1
Enzyme 3 Reactions Not Available
Enzyme 3 Pfam Domain Function
Enzyme 3 Signals
  • None
Enzyme 3 Transmembrane Regions
  • None
Enzyme 3 Essentiality Not Available
Enzyme 3 GenBank ID Protein 162697 Link Image
Enzyme 3 UniProtKB/Swiss-Prot ID P14568 Link Image
Enzyme 3 UniProtKB/Swiss-Prot Entry Name ASSY_BOVIN Link Image
Enzyme 3 PDB ID Not Available
Enzyme 3 Cellular Location Not Available
Enzyme 3 Gene Sequence >1239 bp
ATGTCCGGCAAAGGCTCCGTGGTTCTGGCCTACAGTGGGGGCCTGGACACCTCCTGCATC
CTCGTGTGGCTGAAGGAGCAAGGCTATGACGTCATTGCCTACCTGGCCAACATCGGCCAG
AAAGAAGACTTTGAGGAAGCCAGGAAGAAGGCGCTGAAGCTTGGGGCCAAAAAGGTGTTC
ATTGAGGACATCAGCAAGGAGTTTGTGGAGGAGTTCATCTGGCCGGCCATCCAGTCCAGC
GCACTGTACGAGGACCGATACCTCCTGGGCACCTCTCTCGCCAGGCCCTGCATCGCCCGC
AAGCAGGTGGAGATCGCCCAGCGAGAAGGAGCCAAGTATGTGTCTCACGGCGCCACAGGA
AAGGGGAACGACCAGATCCGGTTTGAGCTCACCTGCTACTCGCTGGCCCCACAGATCAAG
GTCATCGCTCCCTGGAGGATGCCCGAGTTCTATAACCGCTTCCAGGGCCGCAACGATCTG
ATGGAGTATGCGAAGCAACATGGAATCCCCGTCCCAGTCACCCCCAAGAACCCGTGGAGC
ATGGACGAGAACCTGATGCATATCAGCTACGAGGCTGGAATCCTGGAGAACCCCAAGAAC
CAAGCGCCTCCAGGCCTCTACACAAAGACCCAGGACCCGGCCAAAGCCCCCAACAGCCCG
GACATGCTCGAGATCGAGTTCAAGAAAGGGGTCCCCGTGAAGGTGACCAACGTCGGGGAT
GGCACCACCCACAGCACAGCGTTGGAGCTTTTCCTGTACCTGAATGAAGTCGCTGGCAAG
CACGGCGTGGGCCGCATCGACATCGTGGAAAACCGCTTCATCGGGATGAAGTCCCGGGGT
ATCTACGAGACCCCAGCGGGGACGATCCTTTACCACGCTCATTTAGACATCGAGGCCTTC
ACCATGGACCGGGAAGTGCGCAAAATCAAGCAAGGCCTCGGCTTGAAATTCGCCGAGCTG
GTCTACACGGGTTTCTGGCACAGCCCCGAGTGTGAATTTGTCCGCCACTGCATTGCCAAG
TCCCAGGAGCGCGTGGAAGGGAAAGTGCAGGTGTCCGTCTTCAAGGGCCAGGTGTACATC
CTTGGCCGGGAGTCCCCACTGTCCCTCTACAATGAGGAGCTCGTGAGCATGAACGTGCAG
GGAGACTACGAGCCGGTTGATGCCACTGGTTTCATCAACATCAATTCCCTCAGGCTGAAG
GAATATCATCGCCTCCAGAACAAGGTCACCGCCAAATAG
Enzyme 3 GenBank Gene ID M26198 Link Image
Enzyme 3 GeneCard ID ASS1 Link Image
Enzyme 3 GenAtlas ID Not Available
Enzyme 3 HGNC ID Not Available
Enzyme 3 Chromosome Location Chromosome:9
Enzyme 3 Locus 9q34.1
Enzyme 3 SNPs SNPJam Report Link Image
Enzyme 3 General References
  1. [PubMed Link Image]
Enzyme 3 Metabolite References Not Available
Enzyme 4 [top]
Enzyme 4 ID 611
Enzyme 4 Name N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
Enzyme 4 Synonyms
  1. Dimethylarginine dimethylaminohydrolase 2
  2. DDAH-2
  3. DDAHII
  4. Dimethylargininase-2
Enzyme 4 Gene Name DDAH2
Enzyme 4 Protein Sequence >N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
MGTPGEGLGRCSHALIRGVPESLASGEGAAAGLPALDLAKAQREHGVLGGKLRQRLGLQL
VELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEMGDE
NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVTSTSHLRGLCGMGG
PRTVVAGSSEAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGQPGLPPFLLHRGGG
DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHN
Enzyme 4 Number of Residues 285
Enzyme 4 Molecular Weight 29779.7
Enzyme 4 Theoretical pI 5.90
Enzyme 4 GO Classification
Function
Process
Component
Enzyme 4 General Function Amino acid transport and metabolism
Enzyme 4 Specific Function Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in nitric oxide generation
Enzyme 4 Pathways Not Available
Enzyme 4 Reactions Not Available
Enzyme 4 Pfam Domain Function
Enzyme 4 Signals
  • None
Enzyme 4 Transmembrane Regions
  • None
Enzyme 4 Essentiality Not Available
Enzyme 4 GenBank ID Protein 74356281 Link Image
Enzyme 4 UniProtKB/Swiss-Prot ID Q3SX44 Link Image
Enzyme 4 UniProtKB/Swiss-Prot Entry Name DDAH2_BOVIN Link Image
Enzyme 4 PDB ID Not Available
Enzyme 4 Cellular Location Not Available
Enzyme 4 Gene Sequence >858 bp
ATGGGGACGCCAGGGGAGGGGCTGGGCCGCTGCTCCCATGCCCTGATCCGGGGGGTCCCG
GAGAGCCTGGCGTCGGGGGAGGGTGCAGCAGCTGGCCTCCCAGCTCTGGACCTAGCCAAA
GCTCAGAGGGAACATGGGGTGCTGGGGGGTAAGCTGAGGCAGCGATTGGGGCTGCAACTA
GTAGAACTGCCTCCTGAAGAGTCGCTGCCGCTGGGACCGCTGCTCGGTGACACCGCCGTG
ATCCAAGGGGATACGGCTCTAATCACGCGGCCCTGGAGCCCCGCCCGCAGGCCGGAGGTC
GATGGAGTCCGCAAAGCCCTCCAGGACCTGGGGCTCCGAATTGTGGAGATGGGGGACGAG
AACGCAACGCTGGATGGCACTGATGTTCTCTTCACCGGCCGGGAGTTTTTCGTAGGCCTC
TCCAAGTGGACCAATCACCGAGGAGCTGAGATCGTGGCGGACACGTTCCGGGACTTTGCC
GTCTCCACGGTGCCCGTCACAAGCACCTCCCACCTGCGTGGCCTCTGCGGTATGGGGGGA
CCCCGCACCGTGGTGGCGGGTTCCAGCGAAGCTGCCCAAAAAGCTGTCAGGGCAATGGCA
GTGTTGACTGATCACCCCTATGCCTCCCTGACCCTCCCGGATGACGCAGCAGCTGACTGT
CTCTTTCTGCGTCCTGGGCAGCCCGGCCTGCCCCCTTTCCTCCTGCACCGGGGAGGCGGG
GACCTGCCCAACAGCCAAGAGGCACTGCAGAAGCTCTCTGACGTCACCCTCGTACCTGTG
TCCTGTTCAGAACTGGAGAAGGCCGGCGCTGGGCTCAGTTCCCTCTGCCTGGTGCTCAGC
ACACGCCCCCACAACTGA
Enzyme 4 GenBank Gene ID BC104509 Link Image
Enzyme 4 GeneCard ID DDAH2 Link Image
Enzyme 4 GenAtlas ID Not Available
Enzyme 4 HGNC ID Not Available
Enzyme 4 Chromosome Location Chromosome:6
Enzyme 4 Locus 6p21.3
Enzyme 4 SNPs SNPJam Report Link Image
Enzyme 4 General References Not Available
Enzyme 4 Metabolite References Not Available
Enzyme 5 [top]
Enzyme 5 ID 612
Enzyme 5 Name N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
Enzyme 5 Synonyms
  1. Dimethylarginine dimethylaminohydrolase 1
  2. DDAH-1
  3. DDAHI
  4. Dimethylargininase-1
Enzyme 5 Gene Name DDAH1
Enzyme 5 Protein Sequence >N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
MASLGHPATFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGL
QVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMK
DENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSM
AGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPE
EYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINKKVDS
Enzyme 5 Number of Residues 285
Enzyme 5 Molecular Weight 31288.6
Enzyme 5 Theoretical pI 5.88
Enzyme 5 GO Classification
Function
Process
Component
Enzyme 5 General Function Amino acid transport and metabolism
Enzyme 5 Specific Function Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in nitric oxide generation
Enzyme 5 Pathways Not Available
Enzyme 5 Reactions Not Available
Enzyme 5 Pfam Domain Function
Enzyme 5 Signals
  • None
Enzyme 5 Transmembrane Regions
  • None
Enzyme 5 Essentiality Not Available
Enzyme 5 GenBank ID Protein 151554584 Link Image
Enzyme 5 UniProtKB/Swiss-Prot ID P56965 Link Image
Enzyme 5 UniProtKB/Swiss-Prot Entry Name DDAH1_BOVIN Link Image
Enzyme 5 PDB ID Not Available
Enzyme 5 Cellular Location Not Available
Enzyme 5 Gene Sequence >858 bp
ATGGCTTCTCTCGGCCACCCAGCCACCTTTGGCCGGGCCACCCATGTCGTGGTACGGGCG
CTGCCCGAGTCCCTCGCCCAACAGGCGCTGAGGCGCACCAAGGGCGACGAGGTGGATTTC
GCCCGCGCTGAGCGGCAGCACCAGCTCTACGTGGGCGTGCTGGGCAGTAAACTGGGGCTG
CAGGTGGTGCAGCTGCCCGCCGACGAGAGCCTCCCAGACTGCGTGTTCGTGGAGGACGTG
GCCGTGGTGTGCGAGGAGACGGCCCTGATCACCCGCCCCGGGGCGCCGAGCCGGAGGAAG
GAGGCTGACATGATGAAAGAAGCACTAGAAAAACTTCAGCTCAACATAGTAGAGATGAAA
GATGAAAATGCAACTTTAGATGGTGGAGATGTCTTATTCACAGGCAGAGAATTTTTTGTG
GGCCTTTCCAAAAGGACAAATCAACGAGGTGCGGAAATCTTGGCTGATACTTTTAAGGAC
TATGCGGTCTCCACGGTCCCTGTGGTGGATGCTTTGCACTTGAAGAGTTTCTGCAGCATG
GCTGGGCCTAACCTAATCGCTATTGGATCCAGTGAATCTGCACAGAAGGCCCTCAAGATC
ATGCAACAGATGAGTGATCATCGCTACGACAAACTCACAGTGCCTGATGACACGGCCGCA
AACTGCATATACCTGAATATCCCCAGCAAAGGCCACGTCTTGCTGCACCGAACCCCAGAA
GAGTACCCAGAGAGTGCAAAGGTTTATGAAAAGCTGAAGGACCATATGCTGATCCCCGTG
AGCAATTCTGAACTGGAAAAGGTGGACGGGCTGCTCACCTGCAGCTCGGTTTTAATTAAC
AAGAAAGTAGACTCCTGA
Enzyme 5 GenBank Gene ID BC149998 Link Image
Enzyme 5 GeneCard ID DDAH1 Link Image
Enzyme 5 GenAtlas ID Not Available
Enzyme 5 HGNC ID Not Available
Enzyme 5 Chromosome Location Chromosome:1
Enzyme 5 Locus 1p22
Enzyme 5 SNPs SNPJam Report Link Image
Enzyme 5 General References
  1. [PubMed Link Image]
Enzyme 5 Metabolite References Not Available
Enzyme 6 [top]
Enzyme 6 ID 953
Enzyme 6 Name Ornithine carbamoyltransferase, mitochondrial
Enzyme 6 Synonyms
  1. Ornithine transcarbamylase
  2. OTCase
Enzyme 6 Gene Name OTC
Enzyme 6 Protein Sequence >Ornithine carbamoyltransferase, mitochondrial
MLFHLRTLLNNAALRNGHNFVVRNFRCGQPLQDKVQLKGRDLLTLKNFTGEEIKYMLWLS
ADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTDDIHLGV
NESLTDTARVLSSMTDAVLARVYKQSDLDLLAKEASIPIVNGLSDLYHPIQILADYLTLQ
EHYGSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQVATPKGYEPDPSITKMAEQYAKEN
GTKLSLTNDPLEAACGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAAPDWTF
LHCLPRKPEEVDDEVFYSPRSLVSPEAENRKWTIMAVMVSLLTDYSPQLQKPKF
Enzyme 6 Number of Residues 354
Enzyme 6 Molecular Weight 39841.7
Enzyme 6 Theoretical pI 8.30
Enzyme 6 GO Classification
Function
Process
Component
Enzyme 6 General Function Amino acid transport and metabolism
Enzyme 6 Specific Function Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline
Enzyme 6 Pathways
  • Nitrogen metabolism
  • urea cycle
  • L-citrulline from L- ornithine and carbamoyl phosphate:step 1/1
Enzyme 6 Reactions Not Available
Enzyme 6 Pfam Domain Function
Enzyme 6 Signals
  • None
Enzyme 6 Transmembrane Regions
  • None
Enzyme 6 Essentiality Not Available
Enzyme 6 GenBank ID Protein 7381141 Link Image
Enzyme 6 UniProtKB/Swiss-Prot ID Q9N1U7 Link Image
Enzyme 6 UniProtKB/Swiss-Prot Entry Name OTC_BOVIN Link Image
Enzyme 6 PDB ID 1FVO Link Image
Enzyme 6 PDB File Show
Enzyme 6 3D Structure
Enzyme 6 Cellular Location Not Available
Enzyme 6 Gene Sequence >1065 bp
ATGCTGTTTCATCTAAGGACCCTGTTGAACAATGCAGCTCTTAGAAATGGTCACAATTTC
GTGGTTCGAAATTTTCGATGTGGGCAACCACTACAGGATAAAGTACAGCTGAAGGGCCGT
GACCTCCTCACTCTAAAGAACTTTACAGGAGAAGAAATTAAGTATATGCTATGGCTATCA
GCAGATCTGAAATTCAGGATAAAACAGAAAGGAGAGTATTTGCCTTTACTGCAAGGGAAG
TCCTTAGGCATGATTTTTGAAAAAAGAAGTACTCGAACAAGATTGTCCACAGAAACAGGC
TTTGCACTTCTGGGAGGACACCCTTGTTTTCTTACTACGGACGATATTCATTTGGGTGTG
AATGAAAGTCTCACAGATACAGCCCGTGTGTTGTCTAGCATGACAGATGCCGTGCTGGCG
CGAGTGTACAAACAATCAGATCTGGACCTCCTGGCTAAAGAAGCTTCCATCCCAATTGTC
AATGGGCTGTCGGATTTGTACCACCCTATCCAGATCCTGGCTGATTACCTCACGCTCCAG
GAACACTACGGCTCTCTGAAAGGCCTTACCCTCAGCTGGATTGGGGATGGGAATAACATC
CTGCACTCCATCATGATGAGTGCGGCTAAATTCGGGATGCACCTTCAGGTGGCTACCCCA
AAGGGTTATGAGCCGGATCCCAGTATAACCAAGATGGCAGAGCAGTATGCCAAGGAGAAC
GGTACCAAGCTGTCGCTGACAAATGATCCATTGGAAGCAGCTTGTGGAGGCAATGTATTA
ATTACAGACACTTGGATAAGCATGGGACAAGAAGAGGAGAAGAAAAAGCGGCTCCAGGCT
TTCCAAGGTTACCAGGTTACAATGAAGACTGCTAAAGTTGCTGCCCCTGACTGGACATTT
TTACACTGCTTGCCCAGAAAGCCAGAAGAAGTGGACGATGAAGTGTTTTATTCTCCACGA
TCTCTTGTATCCCCAGAGGCCGAAAACAGAAAGTGGACAATCATGGCTGTCATGGTATCC
CTGCTGACAGATTATTCGCCTCAGCTCCAGAAGCCAAAGTTTTGA
Enzyme 6 GenBank Gene ID AF134841 Link Image
Enzyme 6 GeneCard ID OTC Link Image
Enzyme 6 GenAtlas ID Not Available
Enzyme 6 HGNC ID Not Available
Enzyme 6 Chromosome Location Not Available
Enzyme 6 Locus Xp21.1
Enzyme 6 SNPs SNPJam Report Link Image
Enzyme 6 General References Not Available
Enzyme 6 Metabolite References Not Available