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Bovine Rumen Metabolome Database



Showing metabocard for Phosphate (RMDB01429)

Legend: metabolite field enzyme field

Version 1.0
Creation Date 2005-11-16 15:48:42
Update Date 2009-10-28 12:47:30
Accession Number RMDB01429
Common Name Phosphate
Description Phosphate (Pi) is an essential component of life. In classical endocrine regulation, low serum phosphate induces the renal production of the seco-steroid hormone 1,25-dihydroxyvitamin D3 (1,25(OH)2D3).This active metabolite of vitamin D acts to restore circulating mineral levels by increasing absorption in the intestine, reabsorption in the kidney, and mobilization of calcium and phosphate from bone. Thus, chronic renal failure is associated with hyperparathyroidism, which in turn contributes to osteomalacia. Another complication of chronic renal failure is hyperphosphatemia. Fibroblast growth factor 23 (FGF-23) has recently been recognized as a key mediator of phosphate homeostasis, its most notable effect being promotion of phosphate excretion. FGF-23 was discovered to be involved in diseases such as autosomal dominant hypophosphatemic rickets, X-linked hypophosphatemia, and tumor-induced osteomalacia in which phosphate wasting was coupled to inappropriately low levels of 1,25(OH)2D3. FGF-23 is regulated by dietary phosphate in humans: phosphate restriction decreased FGF-23, and phosphate loading increased FGF-23. Phosphate must be actively transported into cells against its electrochemical gradient. In vertebrates, two unrelated families of Na+-dependent Pi transporters carry out this task. Remarkably, the two families transport different Pi species: whereas type II Na+/Pi cotransporters (SCL34) prefer divalent HPO4(2), type III Na+/Pi cotransporters (SLC20) transport monovalent H2PO4. The SCL34 family comprises both electrogenic and electroneutral members that are expressed in various epithelia and other polarized cells. Through regulated activity in apical membranes of the gut and kidney, they maintain body Pi homeostasis, and in salivary and mammary glands, liver, and testes they play a role in modulating the Pi content of luminal fluids. Hyperphosphatemia is a prevalent condition in the dialysis population and is associated with increased risk of mortality. Hypophosphatemia (hungry bone syndrome) has been associated to postoperative electrolyte aberrations and after parathyroidectomy. (PMID: 17581921, 11169009, 11039261, 9159312, 17625581)
Synonyms
  1. NFB Orthophosphate
  2. O-phosphoric acid
  3. Ortho-phosphate
  4. Orthophosphate (PO43-)
  5. Orthophosphate(3-)
  6. Phosphate
  7. Phosphate (PO43-)
  8. Phosphate anion(3-)
  9. Phosphate ion (PO43-)
  10. Phosphate ion(3-)
  11. Phosphate trianion
  12. Phosphate(3-)
  13. Phosphoric acid ion(3-);Pi
Chemical IUPAC Name phosphate
Chemical Formula [PO4]3-
Chemical Structure Structure
Chemical Taxonomy
Kingdom
  • Inorganic
Super Class
  • Inorganic compounds
Class
  • Inorganic Ions and Gases
Sub Class
  • Anions
Family
  • Mammalian_Metabolite
Species
  • anion; phosphoric acid
Biofunction
  • Osmolyte, enzyme cofactor, signalling
Application
Source
  • Endogenous
Average Molecular Weight 94.971
Monoisotopic Molecular Weight 94.953423
Isomeric SMILES [O-]P([O-])([O-])=O
Canonical SMILES [O-]P([O-])([O-])=O
KEGG Compound ID C00009 Link Image
BioCyc ID CPD-8587 Link Image
BiGG ID 33499 Link Image
Wikipedia Link Phosphate Link Image
METLIN ID 3231 Link Image
PubChem Compound 1061 Link Image
PubChem Substance 36534653 Link Image
ChEBI ID 18367 Link Image
CAS Registry Number 14265-44-2
InChI Identifier InChI=1/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
Synthesis Reference Cremer, Josef; Hartmann, Fridolin; Rodis, Franz; Hinz, Arnulf. Preparation of alkali or alkaline earth phosphates with simultaneous recovery of volatile mineral acids. Ger. (1966), 2 pp. CODEN: GWXXAW DE 1227435 19661027 CAN 66:12584 AN 1967:12584
Melting Point (Experimental) Not Available
Experimental Water Solubility 1000 mg/mL [MERCK INDEX (1996); freely soluble] Source: PhysProp
Predicted Water Solubility Not Available Calculated using ALOGPS
Physiological Charge -3
State Solid
Experimental LogP/Hydrophobicity Not Available Source: PhysProp
Predicted LogP/Hydrophobicity -3.61 [MEYLAN,WM & HOWARD,PH (1995)] Calculated using ALOGPS
Material Safety Data Sheet (MSDS)
MOL File Show Link Image
SDF File Show Link Image
PDB File Show Link Image
2D Structure
3D Structure
Experimental PDB ID Not Available
Experimental PDB File Show
Experimental PDB Structure
Experimental 1H NMR Spectrum Not Available
Experimental 13C NMR Spectrum Not Available
Experimental 13C HSQC Spectrum Not Available
Predicted 1H NMR Spectrum Not Available
Not Available
Predicted 13C NMR Spectrum Not Available
Not Available
Mass Spectrum Not Available
Simplified TOCSY Spectrum Not Available
BMRB Spectrum Not Available
Cellular Location
  • Cytoplasm
  • endoplasmic reticulum
  • Extracellular
  • golgi apparatus
  • lysosome
  • mitochondria
  • nucleus
  • peroxisome
Biofluid Location
  • Rumen
Tissue Location Not Available
Concentrations (Normal)
Biofluid Rumen
Value 1000-4000 uM
Age Infant:0-1_yr_old
Sex Both
Condition Normal
Breed Not Available
Experimental Condition Not Available
Comments An increase in the acidity of the ruminal fluid also increased the absorption of phosphate, as did an increase in the ruminal Ca2‡ concentration over the range (1-4)mmol per litre.
References
Concentrations (Abnormal) Not Available
Pathway Names Not Available
HMDB Pathways Not Available
KEGG Pathways Not Available
SimCell Pathways Not Available
General References
  1. Wikipedia Link Image
Metabolic Enzymes
  1. Diphosphomevalonate decarboxylase
  2. Monofunctional C1-tetrahydrofolate synthase, mitochondrial
  3. G protein-coupled receptor kinase 7
  4. Cystic fibrosis transmembrane conductance regulator
  5. Serine/threonine-protein phosphatase dullard
  6. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
  7. Proto-oncogene tyrosine-protein kinase Fyn
  8. [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
  9. Insulin-like growth factor 1 receptor
  10. Dual specificity protein phosphatase 14
  11. Sodium/potassium-transporting ATPase subunit alpha-1
  12. Activin receptor type-2A
  13. Arsenical pump-driving ATPase
  14. Glutamine synthetase
  15. Cytosolic purine 5'-nucleotidase
  16. Fructose-1,6-bisphosphatase isozyme 2
  17. Acylphosphatase-1
  18. Activin receptor type-2B
  19. Calcium-transporting ATPase type 2C member 1
  20. Glyceraldehyde-3-phosphate dehydrogenase
  21. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
  22. Ectonucleoside triphosphate diphosphohydrolase 8
  23. Probable phospholipid-transporting ATPase IIB
  24. Sodium/potassium-transporting ATPase subunit alpha-2
  25. 5'-nucleotidase
  26. Dual specificity protein phosphatase 26
  27. Phosphorylase
  28. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  29. Ectonucleoside triphosphate diphosphohydrolase 1
  30. Dynamin-1
  31. Glucose-6-phosphatase
  32. Beta-adrenergic receptor kinase 2
  33. Dual specificity phosphatase DUPD1
  34. Cell division control protein 2 homolog
  35. Folylpolyglutamate synthase, mitochondrial
  36. Dynamin-2
  37. Interferon-inducible GTPase 5
  38. ITK protein
  39. Glucose-6-phosphatase 3
  40. S-adenosylmethionine synthetase
  41. ATP-citrate synthase
  42. Fructose-1,6-bisphosphatase 1
  43. Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
  44. G protein-coupled receptor kinase 5
  45. YES1 protein
  46. FGR protein
  47. Dual specificity protein phosphatase 10
  48. Dynamin-1-like protein
  49. Tyrosine-protein kinase receptor
  50. Serine/threonine protein phosphatase
  51. Activated CDC42 kinase 1
  52. Integrin-linked protein kinase
  53. Dual specificity protein phosphatase 18
  54. Serine/threonine protein phosphatase
  55. ATP synthase subunit beta, mitochondrial
  56. Putative tyrosine-protein phosphatase auxilin
  57. ATP10D protein
  58. Acylphosphatase-2
  59. 2',3'-cyclic-nucleotide 3'-phosphodiesterase
  60. Eyes absent homolog 2
  61. 3'(2'),5'-bisphosphate nucleotidase 1
  62. Probable phospholipid-transporting ATPase IA
  63. Glutathione synthetase
  64. Alkaline phosphatase
  65. Cell division protein kinase 9
  66. Tyrosine-protein kinase receptor
  67. Nucleoside-triphosphatase C1orf57 homolog
  68. Beta-adrenergic receptor kinase 1
  69. Tyrosine-protein kinase CSK
  70. Acetyl-CoA carboxylase 1
  71. Activin receptor type-1
  72. Dual specificity protein phosphatase 6
  73. Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
  74. Serine/threonine protein phosphatase
  75. Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
  76. Enolase-phosphatase E1
  77. Tyrosine-protein kinase
Enzyme 1 [top]
Enzyme 1 ID 101
Enzyme 1 Name Diphosphomevalonate decarboxylase
Enzyme 1 Synonyms
  1. Mevalonate pyrophosphate decarboxylase
  2. Mevalonate (diphospho)decarboxylase
Enzyme 1 Gene Name MVD
Enzyme 1 Protein Sequence >Diphosphomevalonate decarboxylase
MASEKPIVVVTCTAPVNIAVVKYWGKRDEELILPINSSLSVTLHQDQLKTTTTAAISRDF
TEDRIWLNGREEDMGHPRLQACLREIRRLARKRRSDGHEDPLPLSLSYKVHVASENNFPT
AAGLASSAAGYACLAYTLARVYGVDSDLSEVARRGSGSACRSLYGGFVEWQMGERPDGKD
SVACQVAPESHWPELRVLILVVSAERKPMGSTAGMQTSVETSALLKFRAEALVPPRMAEM
TRCIRERNFQAFGQLTMKDSNQFHATCLDTFPPISYLSDTSRRIIQLVHRFNAHHGQTKV
AYTFDAGPNAVVFTLDDTVAEFVAAVRHSFPPESNGDKFLKGLPVEPVLLSDELKAVLGM
DPVPGSIRYIIATQVGPGPQVLDDPGAHLLGPDGLPKPAA
Enzyme 1 Number of Residues 400
Enzyme 1 Molecular Weight 43731.4
Enzyme 1 Theoretical pI 6.90
Enzyme 1 GO Classification
Function
Process
Component
Enzyme 1 General Function Lipid transport and metabolism
Enzyme 1 Specific Function Performs the first committed step in the biosynthesis of isoprenes
Enzyme 1 Pathways
  • Steroid biosynthesis
  • cholesterol biosynthesis
Enzyme 1 Reactions Not Available
Enzyme 1 Pfam Domain Function
Enzyme 1 Signals
  • None
Enzyme 1 Transmembrane Regions
  • None
Enzyme 1 Essentiality Not Available
Enzyme 1 GenBank ID Protein 112362156 Link Image
Enzyme 1 UniProtKB/Swiss-Prot ID Q0P570 Link Image
Enzyme 1 UniProtKB/Swiss-Prot Entry Name ERG19_BOVIN Link Image
Enzyme 1 PDB ID Not Available
Enzyme 1 Cellular Location Not Available
Enzyme 1 Gene Sequence >1203 bp
ATGGCCTCAGAGAAGCCGATCGTGGTGGTGACTTGCACCGCGCCCGTCAACATCGCTGTC
GTCAAGTACTGGGGAAAGCGAGATGAGGAGCTGATCCTGCCCATCAATTCCTCTCTGAGC
GTCACATTGCACCAGGATCAGTTGAAAACCACCACGACGGCCGCCATCAGCAGGGACTTC
ACAGAGGACCGGATTTGGCTGAATGGCCGGGAGGAGGATATGGGGCACCCTCGCCTCCAG
GCCTGCCTGAGGGAGATCCGCCGCCTGGCCCGTAAGCGGAGGAGCGACGGCCATGAAGAC
CCACTGCCTCTCAGCCTCAGCTACAAGGTTCATGTGGCCTCGGAGAACAACTTCCCCACG
GCTGCAGGCCTGGCCTCCTCGGCTGCAGGCTATGCCTGCTTAGCCTACACCCTGGCCCGG
GTCTATGGGGTGGACAGCGATCTGTCGGAAGTGGCCCGCAGGGGCTCAGGCAGCGCCTGC
CGCAGCCTGTACGGTGGCTTTGTGGAGTGGCAGATGGGTGAGCGCCCTGATGGGAAGGAC
AGCGTCGCCTGTCAGGTGGCCCCCGAGTCACACTGGCCGGAGCTCCGAGTCCTGATCCTC
GTGGTGAGCGCTGAGAGGAAGCCGATGGGCAGCACGGCAGGCATGCAGACCAGCGTGGAG
ACCAGTGCCCTGCTCAAGTTCCGGGCAGAGGCACTGGTGCCGCCGCGCATGGCCGAGATG
ACCCGCTGCATCAGGGAGCGCAACTTCCAGGCCTTTGGCCAGCTGACCATGAAGGACAGC
AACCAGTTCCACGCCACCTGCCTGGACACCTTCCCGCCCATCTCCTACCTCAGTGACACA
TCCCGGCGCATCATCCAGCTGGTGCACCGCTTCAACGCTCACCATGGGCAGACCAAGGTG
GCGTACACTTTTGATGCGGGTCCCAACGCTGTGGTCTTCACTCTGGATGACACCGTGGCT
GAGTTTGTGGCTGCCGTGAGGCACAGCTTCCCCCCTGAGTCGAACGGAGACAAGTTTCTG
AAGGGGCTGCCCGTGGAGCCCGTCCTGCTCTCAGATGAGCTTAAAGCTGTGCTGGGCATG
GACCCCGTCCCTGGCAGCATCAGATACATCATTGCCACCCAGGTGGGACCCGGGCCTCAG
GTCCTGGATGACCCTGGCGCTCATCTCCTGGGTCCTGACGGTCTGCCAAAGCCAGCTGCC
TGA
Enzyme 1 GenBank Gene ID BC120432 Link Image
Enzyme 1 GeneCard ID MVD Link Image
Enzyme 1 GenAtlas ID Not Available
Enzyme 1 HGNC ID Not Available
Enzyme 1 Chromosome Location Chromosome:1
Enzyme 1 Locus 16q24.3
Enzyme 1 SNPs SNPJam Report Link Image
Enzyme 1 General References Not Available
Enzyme 1 Metabolite References Not Available
Enzyme 2 [top]
Enzyme 2 ID 118
Enzyme 2 Name Monofunctional C1-tetrahydrofolate synthase, mitochondrial
Enzyme 2 Synonyms
  1. Formyltetrahydrofolate synthetase
Enzyme 2 Gene Name MTHFD1L
Enzyme 2 Protein Sequence >Monofunctional C1-tetrahydrofolate synthase, mitochondrial
MSARLPFVLRRLARPQHPGSPRRLPSLCRASSGRGSGCGGGEGLLGQQRLRDTQAGSSRG
PGSPAPPARDSIVREVIQNSKEVLSLLQEKTPTFKPVLAIIQAGDDNLMQEVNQNLAEEA
GLNITHICLPAESGEDEIIDEILKINEDSRVHGLALQIAETSFSNKILNALKPEKDVDGL
TDVNLGKLVRGDAHECFISPVARAVIELLEKSGVSLDGKKILVIGAHGSLEATLQCLFQR
KGSMTMSSQWKTPQLQGKLQEADIVVLGSPKPEEIPLSWIQPGTTVFNCSHDFLSGKAAC
ISSGVHGISPIAEDVSLLAAALRIQNMVSSGRRWLREQQHRRWRLHCLKLQPLSPVPSDI
EISRAQTPKAVEILAKEIGLLADEIEIYGKSKAKVRLSLLERLKDQADGKYVLVAGITPT
PLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNL
HLTGDIHAITAANNLLAAAIDARILHENTQTDKALYNRLVPSVNGVREFSKIQLARLKRL
GINKTDPSALTEEEMRKFARLDIDPSTITWQRVVDTNDRFLRKITIGQANTEKGCSRQAQ
FDIAVASEIMAVLALTDSLSDMKERLGRMVVASDRNGQPVTADDLGVTGALTVLMKDAIK
PNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEGGFVVTEAGFGADIGMEKF
FNIKCRASGLVPSVVVLVATVRALKMHGGGPSVTAGVPLRKEYTEENLQLVADGCCNLEK
QIQIAQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFNAVPCYHWSIGGKGSVDLAW
AVREAASKESRFQFLYDVQLPIVEKIRTIAQSVYGAKDIELSPEAQSKIDRYTEQGFGNL
PICMAKTHLSLSHQPDKKGVPKGFILPISDVRASIGAGFIYPLVGTMSTMPGLPTRPCFY
DIDLDTETEQVKGLF
Enzyme 2 Number of Residues 975
Enzyme 2 Molecular Weight 105226.2
Enzyme 2 Theoretical pI 7.78
Enzyme 2 GO Classification
Function
Process
Component
Enzyme 2 General Function Nucleotide transport and metabolism
Enzyme 2 Specific Function May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2
Enzyme 2 Pathways
  • One-carbon metabolism
  • tetrahydrofolate interconversion
Enzyme 2 Reactions Not Available
Enzyme 2 Pfam Domain Function
Enzyme 2 Signals
  • None
Enzyme 2 Transmembrane Regions
  • None
Enzyme 2 Essentiality Not Available
Enzyme 2 GenBank ID Protein 111308519 Link Image
Enzyme 2 UniProtKB/Swiss-Prot ID Q0VCR7 Link Image
Enzyme 2 UniProtKB/Swiss-Prot Entry Name C1TM_BOVIN Link Image
Enzyme 2 PDB ID Not Available
Enzyme 2 Cellular Location Not Available
Enzyme 2 Gene Sequence >2928 bp
ATGAGCGCGCGCCTGCCGTTCGTCCTGCGCCGGCTCGCGCGCCCGCAGCACCCCGGCTCG
CCGCGCCGCCTCCCATCTCTTTGTCGCGCCAGCAGCGGCAGGGGCAGCGGATGTGGCGGC
GGGGAGGGTCTCCTCGGGCAACAGCGGCTGCGGGATACCCAGGCCGGGAGCAGCCGGGGC
CCGGGCAGCCCGGCGCCCCCAGCTCGGGACTCGATCGTCCGAGAAGTCATTCAGAATTCG
AAAGAAGTTCTGAGTTTATTGCAAGAAAAGACCCCTACCTTTAAGCCGGTTCTTGCTATT
ATTCAGGCAGGTGATGATAACTTGATGCAAGAAGTAAACCAGAATTTGGCTGAGGAGGCT
GGTCTGAACATCACCCACATCTGCCTTCCTGCGGAGAGCGGGGAAGATGAGATTATAGAT
GAGATCCTGAAGATTAATGAAGACAGCAGAGTACATGGCCTTGCCCTTCAGATCGCTGAG
ACCTCATTTAGCAACAAAATCCTCAATGCTTTGAAACCAGAAAAAGATGTGGATGGATTA
ACGGATGTCAACCTGGGGAAGTTGGTCCGAGGAGATGCCCATGGGTGTTTTATTTCACCT
GTGGCCAGAGCTGTAATCGAACTTCTTGAAAAGTCAGGTGTCAGCTTAGATGGAAAGAAG
ATCTTGGTAATAGGAGCCCATGGGTCTTTGGAAGCCACCCTACAATGTCTGTTCCAGAGA
AAAGGGTCCATGACAATGAGCTCCCAGTGGAAAACACCTCAGCTTCAAGGCAAGCTACAG
GAGGCTGATATTGTGGTCTTGGGCTCACCCAAGCCAGAAGAGATCCCCCTTTCTTGGATT
CAACCGGGAACTACTGTTTTCAACTGTTCGCATGACTTTCTATCAGGGAAGGCTGCATGC
ATTTCTTCTGGCGTCCATGGTATTAGTCCCATCGCCGAAGATGTGAGTCTCCTTGCTGCT
GCTCTGCGGATTCAGAACATGGTCAGCAGCGGAAGGAGATGGCTCCGTGAGCAGCAGCAC
CGCAGATGGAGACTTCACTGCTTGAAACTTCAGCCTCTGTCCCCTGTACCAAGTGATATC
GAGATTTCGAGAGCGCAGACTCCAAAAGCTGTGGAGATCCTTGCCAAGGAGATAGGATTG
CTTGCAGACGAAATTGAAATCTATGGCAAAAGCAAAGCCAAAGTACGTTTGTCCTTGTTG
GAAAGGTTAAAGGATCAAGCAGATGGAAAATACGTCTTGGTTGCTGGGATCACACCCACC
CCTCTTGGAGAAGGAAAAAGTACAGTTACAATTGGGCTTGTACAGGCATTGACTGCGCAC
CTGAACGTCAACTCCTTTGCCTGTCTCAGGCAGCCTTCTCAAGGACCAACTTTCGGAGTT
AAAGGAGGAGCTGCAGGTGGTGGATATGCCCAGGTCATCCCTATGGAGGAGTTCAACCTT
CACCTTACTGGGGACATCCACGCCATTACTGCTGCCAATAATTTGCTGGCTGCCGCTATC
GACGCAAGGATTTTGCATGAAAACACTCAAACAGATAAGGCCCTGTATAATCGACTGGTT
CCTTCAGTGAATGGTGTTCGAGAATTTTCAAAAATTCAACTTGCTCGGCTGAAAAGACTG
GGAATAAATAAGACTGATCCGAGTGCGCTGACAGAAGAGGAAATGAGGAAATTTGCCCGT
CTTGACATCGACCCCTCCACCATCACATGGCAGAGAGTTGTGGATACCAATGACCGATTT
CTACGGAAAATAACCATTGGGCAGGCGAACACAGAGAAGGGCTGTTCCCGGCAGGCGCAG
TTTGACATCGCAGTGGCCAGTGAAATCATGGCAGTGCTGGCTCTGACCGACAGCCTATCG
GACATGAAGGAGCGGCTGGGAAGAATGGTGGTGGCCAGTGACAGAAATGGACAGCCTGTG
ACAGCAGACGACTTGGGGGTGACAGGTGCTTTGACTGTTCTGATGAAAGACGCGATAAAA
CCAAATCTGATGCAGACCCTAGAAGGGACGCCTGTATTTGTGCATGCTGGCCCCTTTGCC
AACATCGCTCATGGCAACTCTTCAGTGTTGGCTGATAAAATTGCCCTGAAACTGGTTGGG
GAAGGAGGATTTGTGGTGACTGAAGCTGGCTTTGGTGCTGATATTGGCATGGAGAAATTC
TTCAACATCAAGTGCAGAGCTTCTGGTTTGGTGCCCAGCGTTGTGGTTCTGGTGGCGACC
GTGCGGGCTCTGAAGATGCATGGAGGTGGACCGAGCGTAACTGCTGGGGTCCCTCTTAGA
AAGGAATATACCGAAGAGAACCTCCAGCTGGTGGCAGATGGCTGCTGTAACCTGGAGAAG
CAAATTCAGATCGCTCAGCTCTTCGGGGTCCCTGTTGTTGTGGCTCTGAATGTCTTCAAG
ACCGACACCCGCGCAGAGATTGACTTGGTGTGTGAGCTTGCGAAGCGGGCCGGCGCCTTC
AATGCAGTCCCCTGCTATCACTGGTCGATTGGTGGGAAAGGGTCAGTGGACCTGGCTTGG
GCTGTGAGAGAAGCTGCAAGCAAAGAAAGTCGTTTCCAGTTCCTGTATGATGTGCAGCTT
CCAATTGTGGAAAAGATAAGAACCATTGCCCAGTCTGTCTATGGAGCCAAAGATATTGAA
CTCTCTCCAGAAGCACAATCCAAAATAGATCGTTACACGGAACAGGGATTTGGAAATTTG
CCCATCTGCATGGCGAAGACCCACCTCTCCCTGTCTCACCAACCTGACAAGAAAGGCGTA
CCCAAGGGTTTCATTCTACCCATTAGTGACGTCCGGGCCAGCATAGGCGCCGGATTCATT
TACCCATTGGTTGGAACGATGAGCACCATGCCAGGACTGCCAACTCGGCCCTGCTTCTAC
GACATAGATCTTGATACAGAAACAGAGCAGGTTAAAGGCTTGTTCTGA
Enzyme 2 GenBank Gene ID BC120038 Link Image
Enzyme 2 GeneCard ID MTHFD1L Link Image
Enzyme 2 GenAtlas ID Not Available
Enzyme 2 HGNC ID Not Available
Enzyme 2 Chromosome Location Chromosome:6
Enzyme 2 Locus 6q25.1
Enzyme 2 SNPs SNPJam Report Link Image
Enzyme 2 General References Not Available
Enzyme 2 Metabolite References Not Available
Enzyme 3 [top]
Enzyme 3 ID 137
Enzyme 3 Name G protein-coupled receptor kinase 7
Enzyme 3 Synonyms
  1. G protein-coupled receptor kinase GRK7
Enzyme 3 Gene Name GRK7
Enzyme 3 Protein Sequence >G protein-coupled receptor kinase 7
MVDMGGLDNLIANTAYLQARKSSDADSKELQRRRRSLMLPGPQSCEQLRQALATDFHSLC
EQQPIGRRLFRDFLATVPAYQEARGFLEEVQSWELAEEGPAKGSALQGLVTTCAAAPVPG
RPHPFFSPALVTKCQAATTDDDRASLVELAKAEVMAFLQDQPFREFLASPFYDKFLQWKV
FEMQPVSDKYFEEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKNGEKMALLEK
EILERVSSPFIVSLAYAFESKSHLCLVMSLMNGGDLKFHIYSVGEPGLDMSRVIFYSAQI
TCGVLHLHSLGIVYRDMKPENVLLDDLGNCRLSDLGLAVQIQDGKPITQRAGTNGYMAPE
ILMEKASYSYPVDWFAMGCSIYEMVAGRTPFRDYKEKVSKEDLKQRTLKEEVRFQHSNFT
EEAKDICRLFLAKTPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLVEPPFVPDPSVVYA
KDINEIDDFSEVRGVEFDDNDKQFFQRFATGAVPIAWQEEIIETGPFAELNDPNRPAGCG
EGSSRSGVCLLL
Enzyme 3 Number of Residues 552
Enzyme 3 Molecular Weight 62124.5
Enzyme 3 Theoretical pI 5.93
Enzyme 3 GO Classification
Function
Process
Component
Enzyme 3 General Function Involved in ATP binding
Enzyme 3 Specific Function Phosphorylates cone opsins thereby initiating their deactivation
Enzyme 3 Pathways Not Available
Enzyme 3 Reactions Not Available
Enzyme 3 Pfam Domain Function
Enzyme 3 Signals
  • None
Enzyme 3 Transmembrane Regions
  • None
Enzyme 3 Essentiality Not Available
Enzyme 3 GenBank ID Protein 17933490 Link Image
Enzyme 3 UniProtKB/Swiss-Prot ID Q8WMV0 Link Image
Enzyme 3 UniProtKB/Swiss-Prot Entry Name GRK7_BOVIN Link Image
Enzyme 3 PDB ID Not Available
Enzyme 3 Cellular Location Not Available
Enzyme 3 Gene Sequence >1659 bp
ATGGTCGACATGGGAGGTCTAGACAACCTGATCGCCAACACGGCCTACCTGCAGGCTCGG
AAGTCCTCGGACGCCGACAGCAAGGAGCTGCAGCGCCGGCGCCGGAGCCTGATGCTGCCC
GGGCCGCAGAGCTGCGAGCAGCTCCGCCAGGCCCTGGCCACCGACTTCCATAGTCTGTGC
GAGCAGCAGCCTATCGGCCGCCGCCTCTTCCGGGACTTCCTGGCCACGGTGCCTGCATAC
CAGGAGGCCAGGGGCTTTCTGGAGGAGGTGCAGAGCTGGGAGCTGGCCGAAGAGGGCCCC
GCCAAGGGCAGCGCGCTGCAGGGGCTGGTGACCACTTGTGCCGCCGCCCCTGTCCCGGGG
CGCCCACACCCCTTCTTCAGCCCAGCTCTGGTCACCAAGTGCCAAGCAGCCACCACCGAC
GACGATCGAGCATCCCTGGTGGAGCTGGCCAAGGCCGAGGTCATGGCCTTCCTGCAGGAC
CAGCCCTTCCGGGAGTTCCTAGCCAGTCCCTTCTATGACAAGTTTCTGCAATGGAAAGTC
TTCGAGATGCAGCCAGTGTCAGACAAGTACTTTGAAGAGTTCCGGGTGCTGGGGAAAGGT
GGTTTCGGGGAGGTATGTGCTGTCCAGGTGAAAAACACCGGTAAGATGTATGCCTGTAAG
AAACTGGACAAGAAGCGACTGAAGAAGAAAAATGGTGAGAAAATGGCTCTCTTGGAAAAG
GAAATCTTGGAGAGGGTCAGCAGCCCGTTCATTGTCTCTCTGGCGTACGCCTTTGAGAGC
AAGTCCCATCTCTGCCTGGTGATGAGCCTGATGAATGGTGGAGACCTCAAGTTCCACATC
TACAGTGTGGGTGAACCAGGCCTGGACATGAGCAGGGTGATCTTCTACTCGGCCCAGATA
ACCTGTGGCGTGCTGCACCTCCACTCCCTCGGCATCGTCTATCGGGACATGAAACCCGAG
AACGTGCTTCTGGACGACCTCGGCAACTGCAGACTGTCTGACCTGGGGCTGGCCGTGCAG
ATCCAGGATGGTAAACCCATCACCCAGAGGGCTGGAACTAATGGTTATATGGCTCCTGAA
ATCCTAATGGAAAAAGCAAGTTATTCCTATCCTGTGGACTGGTTTGCAATGGGATGCAGT
ATTTATGAAATGGTTGCTGGACGAACACCATTCAGAGATTACAAGGAAAAAGTCAGTAAA
GAGGATTTAAAGCAAAGAACACTGAAAGAGGAAGTCAGATTCCAACACAGTAACTTCACA
GAGGAAGCAAAAGATATTTGCAGACTCTTCTTGGCTAAGACACCAGAGCAACGCTTAGGA
AGCAGAGAAAAGTCTGATGATCCCAGGAAACACCATTTCTTCAAAACCATCAATTTTCCT
CGCCTGGAAGCCGGCCTAGTTGAACCTCCATTTGTGCCAGACCCATCAGTGGTTTATGCC
AAAGACATCAATGAAATCGATGATTTCTCTGAGGTTCGAGGAGTTGAATTTGATGATAAC
GATAAGCAGTTCTTTCAAAGGTTTGCAACAGGTGCTGTCCCCATAGCTTGGCAGGAAGAG
ATTATAGAAACGGGACCGTTTGCAGAATTGAATGACCCCAACAGGCCCGCAGGTTGTGGG
GAGGGTTCATCCAGGTCTGGCGTATGTTTGTTATTATAA
Enzyme 3 GenBank Gene ID AY049726 Link Image
Enzyme 3 GeneCard ID GRK7 Link Image
Enzyme 3 GenAtlas ID Not Available
Enzyme 3 HGNC ID Not Available
Enzyme 3 Chromosome Location Chromosome:3
Enzyme 3 Locus 3q21-q23
Enzyme 3 SNPs SNPJam Report Link Image
Enzyme 3 General References Not Available
Enzyme 3 Metabolite References Not Available
Enzyme 4 [top]
Enzyme 4 ID 138
Enzyme 4 Name Cystic fibrosis transmembrane conductance regulator
Enzyme 4 Synonyms
  1. CFTR
  2. Channel conductance-controlling ATPase
  3. cAMP-dependent chloride channel
  4. ATP-binding cassette transporter sub-family C member 7
Enzyme 4 Gene Name CFTR
Enzyme 4 Protein Sequence >Cystic fibrosis transmembrane conductance regulator
MQRSPLEKASVVSKLFFSWTRPILKKGYRQRLELSDIYHISSSDSADNLSEKLEREWDRE
LASKKNPKLINALRRCFFWRFMFYGIILYLGEVTKAVQPLLLGRIIASYDPDNKVERSIA
IYLGIGLCLLFIVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQL
VSLLSNNLNKFDEGLALAHFVWIAPLQVTLLMGLLWELLQAFTFCGLAFLIVLALLQAGL
GKMMMKYRDQRAGKINERLVITSEMIENIQSVKAYCWEEAMEKIIENLRQTELKLTRKAA
YVRYLNSSAFFFSGFFVVFLSVLPYALLKGIILRKIFTTISFCIVLRMAVTRQFPWAVQT
WYDSLGAINKIQDFLQKQEYKTLEYNLTTTDVVMENVTAFWEEGFSKLFEKAKENNNSRK
ISNGDNSLFFSNLLLGTPVLKDISFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSEGK
IKHSGRISFCSQYSWIMPGTIKDNIIFGVSYDEYRYRSVIKACQLEEDISKFAEKDNVVL
GEGGITLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCICKLMANKTRI
LVTSKMEHLKKADKILILHEGSIYFYGTFSELQNQRPDFSSKLMGCDTFDQFTAERRNSI
ITETLRRFSLEGDTSVSWNETKKPSFKQTGEFGEKRKNSILSSINSIRKFSVVQKTSLQM
NGIEGAADAPLERRLSLVPHSEPGEGILPRSNAVNSGPTFLGGRRQSVLNLMTGSSVNQG
QSIHRKTATSTRKMSLAPQASLAEIDIYSRRLSQDTGLEISEEINEEDLRDCFFDDVENI
PAVTTWNTYLRYITVHKSLMFVLIWCLVVFLVEVAASLVVLCLFPKIFFQDKGNSTKSAN
NSYAVIITSTSSYYIFYIYVGVADTLLALGLFRGLPLVHTLITVSKTLHHKMLQSVLQAP
MSTLNTLKTGGILNRFSKDIAVLDDLLPLTIFDFVQLLLIVIGAVVVVSVLQPYIFLATV
PVIAAFILLRAYFLHTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHK
ALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGEGEGRVGIILTLAMNIM
GTLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEDGKPNNSFRPSKDSQPSKVMIIENQHVK
KDDIWPSGGQMTVKDLTAKYTDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLLAFLR
LLNTKGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSGTFRKNLDPYGQWSDQEIWKVA
DEVGLRSVIEQFPGKLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPI
TYQIIRRTLKQAFANCTVILSEHRIEAMLECQRFLVIEENKVRQYDSIQRMLSEKSLFRQ
AISPADRLKLLPHRNSSRQRSRSNIAALKEETEEEVQETKL
Enzyme 4 Number of Residues 1481
Enzyme 4 Molecular Weight 167756.6
Enzyme 4 Theoretical pI 9.54
Enzyme 4 GO Classification
Function
Process
Component
Enzyme 4 General Function Defense mechanisms
Enzyme 4 Specific Function Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter
Enzyme 4 Pathways Not Available
Enzyme 4 Reactions Not Available
Enzyme 4 Pfam Domain Function
Enzyme 4 Signals
  • None
Enzyme 4 Transmembrane Regions
  • 81-103 118-138 195-215 221-241 308-328 331-350 860-880 912-932 991-1011 1014-1034 1103-1123 1129-1149
Enzyme 4 Essentiality Not Available
Enzyme 4 GenBank ID Protein 163742 Link Image
Enzyme 4 UniProtKB/Swiss-Prot ID P35071 Link Image
Enzyme 4 UniProtKB/Swiss-Prot Entry Name CFTR_BOVIN Link Image
Enzyme 4 PDB ID 1XMI Link Image
Enzyme 4 PDB File Show
Enzyme 4 3D Structure
Enzyme 4 Cellular Location Not Available
Enzyme 4 Gene Sequence >4446 bp
ATGCAGAGGTCGCCTCTGGAAAAGGCCAGCGTCGTCTCCAAAGTTTTTTTCAGCTGGACC
AGACCAATTTTGAAGAAAGGATACAGACAGCGCCTGGAATTGTCAGACATATACCATATC
TCTTCTTCTGATTCTGCTGACAATCTATCTGAAAAATTGGAAAGAGAATGGGACAGAGAA
CTGGCTTCAAAGAAAAATCCCAAACTCATAAATGCCCTTCGACGATGCTTTTTCTGGAGA
TTTATGTTCTATGGAATCATATTATATTTAGGGGAAGTCACCAAAGCAGTCCAGCCTCTC
TTACTGGGAAGAATCATAGCTTCCTATGACCCAGATAACAAGGTGGAACGCTCCATTGCC
ATTTACTTAGGCATAGGCCTATGCCTTCTCTTTATCGTGAGGACACTGCTCCTGCACCCA
GCCATTTTTGGTCTCCATCACATTGGAATGCAGATGAGAATAGCTATGTTTAGTTTGATT
TATAAGAAGACTTTGAAGCTATCAAGCCGTGTTCTGGATAAAATAAGTATTGGACGACTT
GTTAGTCTCCTTTCCAACAACCTGAACAAATTTGATGAAGGACTCGCACTGGCACATTTT
GTGTGGATCGCTCCTCTGCAAGTGACGCTGCTCATGGGGCTGCTCTGGGAGTTGTTGCAG
GCCTTCACCTTCTGTGGGCTTGCTTTCCTCATAGTCCTCGCCCTTCTTCAAGCCGGATTA
GGGAAAATGATGATGAAGTACAGAGATCAGAGAGCTGGAAAGATCAATGAAAGAGTGGTG
ATAACGTCAGAAATGATTGAAAATATCCAATCAGTTAAGGCATACTGCTGGGAAGAAGCA
ATGGAAAAAATCATTGAAAACCTAAGACAAACAGAACTGAAACTCACCCGGAAGGCAGCC
TATGTGAGATACCTCAATAGCTCAGCCTTCTTCTTCTCAGGGTTCTTTGTGGTATTTTTA
TCTGTGCTTCCTTATGCACTGCTCAAAGGAATCATCCTTCGAAAAATATTCACAACCATC
TCATTCTGCATCGTTCTGCGCATGGCAGTTACTCGGCAGTTCCCCTGGGCTGTACAAACT
TGGTATGATTCTCTGGGAGCAATAAACAAAATACAGGATTTCTTACAAAAGCAAGAATAT
AAGACATTGGAATATAACTTAACAACTACAGATGTAGTGATGGATAATGTAACAGCCTTC
TGGGAGGAGGGATTTAGTAAATTATTTGAGAAAGCAAAAGAAAATAATAACAATAGAAAA
ATTTCCAATGGTGATAACAGCCTCTTCTTCAGTAACTTACTTCTTGGTACTCCTGTCCTG
AAAGATATCAGTTTCAAGATAGAAAGAGGACAGTTGTTGGCAGTTGCTGGATCTACGGGA
GCAGGCAAGACTTCACTTCTCTTGATGATTATGGGAGAATTGGAAGCTTCAGAGGGTAAA
ATTAAGCACAGTGGAAGAATTTCATTCTGCTCTCAGTATTCCTGGATCATGCCTGGAACC
ATTAAAGATAACATCATCTTTGGTGTTTCCTATGATGAATATAGATATAGAAGTGTCATC
AAAGCATGCCAACTAGAAGAGGACATCTCCAAGTTTGCAGAGAAAGACAACGTAGTTCTC
GGAGAAGGTGGAATCACACTGAGTGGAGGTCAGCGAGCGAGAATTTCTTTAGCAAGAGCA
GTATACAAAGATGCTGATTTGTACCTATTAGACTCTCCTTTTGGATATCTAGATGTTTTA
ACAGAGAAAGAAATATTTGAAAGCTGTATCTGTAAATTGATGGCTAACAAAACTAGGATT
TTGGTCACTTCTAAAATGGAGCACTTAAAGAAAGCTGACAAAATATTAATTTTACATGAA
GGTAGCATCTATTTTTATGGGACATTTTCTGAATTACAAAATCAGCGGCCCGACTTCAGC
TCGAAGCTCATGGGATGTGACACTTTCGACCAGTTTACTGCAGAACGAAGAAATTCAATC
ATAACTGAGACTTTACGGCGTTTCTCATTAGAAGGAGATACTTCTGTGTCCTGGAATGAA
ACGAAAAAGCCTTCTTTTAAACAGACTGGAGAGTTTGGTGAAAAAAGGAAGAACTCCATT
CTCAGTTCAATCAACTCTATAAGGAAATTTTCAGTTGTACAAAAGACTTCATTACAAATG
AATGGTATTGAAGGAGCTGCTGATGCGCCTTTAGAGAGAAGACTATCCTTAGTTCCCCAT
TCTGAACCTGGAGAGGGGATCCTGCCTCGGAGCAATGCAGTCAACAGTGGCCCCACATTT
CTGGGAGGGAGGAGGCAGTCCGTTCTGAACCTTATGACCGGCTCCTCAGTGAACCAAGGT
CAAAGCATTCATCGAAAGACAGCGACATCCACACGAAAAATGTCACTGGCTCCTCAGGCA
AGCTTAGCCGAAATAGATATATATTCAAGACGGTTATCTCAAGATACTGGCTTGGAAATA
AGTGAAGAAATTAATGAAGAAGATTTAAGGGATTGCTTTTTTGATGATGTGGAGAACATA
CCAGCAGTGACTACATGGAACACATACCTTCGATATATTACTGTCCACAAGAGCTTAATG
TTTGTGCTAATTTGGTGCTTAGTCGTTTTTCTGGTTGAGGTGGCCGCTTCTTTGGTTGTG
TTGTGCCTATTTCCGAAAATATTTTTTCAAGACAAAGGAAACAGTACTAAGAGTGCAAAT
AACAGTTATGCAGTGATCATCACCAGCACCAGCTCGTATTATATTTTTTACATTTATGTG
GGAGTGGCTGACACTTTGCTTGCTCTAGGACTCTTCAGAGGTTTACCACTGGTGCATACT
CTAATCACAGTGTCAAAAACTTTACACCACAAAATGCTACAGTCTGTTCTTCAAGCCCCT
ATGTCAACCCTCAACACGTTGAAAACAGGTGGGATTCTTAATAGATTCTCCAAAGATATA
GCAGTTTTGGATGATCTTCTGCCTCTTACCATATTTGATTTTGTTCAGTTGTTATTAATT
GTGATCGGAGCTGTGGTGGTCGTCTCAGTTTTACAGCCCTACATCTTCCTAGCTACAGTG
CCAGTGATAGCGGCTTTTATTCTCTTGAGAGCCTACTTCCTCCACACCTCCCAGCAACTC
AAGCAGCTGGAATCTGAAGGCAGGAGTCCAATTTTCACTCATCTTGTTACAAGTTTAAAA
GGACTATGGACACTTCGTGCCTTGGACCGGCAGCCTTACTTTGAAACTTTATTCCACAAA
GCTCTGAATTTACATACTGCCAACTGGTTCTTGTATCTGTCAACACTGCGCTGGTTCCAA
ATGAGAATAGAAATGATTTTTGTCATCTTCTTCATTGCTGTTACCTTCATTTCCATTTTA
ACAACAGGTGAAGGAGAAGGAAGAGTTGGGATTATTCTAACTTTAGCCATGAATATCATG
GGTACATTGCAGTGGGCTGTAAACTCTAGCATAGATGTGGATAGCTTGATGCGATCTGTG
AGCCGAGTCTTTAAGTTTATTGATATGCCAACAGAAGATGGTAAACCTAACAATTCATTC
AGACCATCCAAGGATAGTCAGCCCTCAAAAGTTATGATCATTGAGAATCAACATGTGAAG
AAAGATGACATCTGGCCCTCAGGGGGCCAAATGACTGTCAAAGACCTCACAGCAAAGTAT
ACAGATGGAGGGAATGCCATACTAGAGAACATATCCTTCTCAATAAGCTCCGGCCAGAGG
GTGGGCCTCTTGGGAAGAACTGGATCAGGGAAGAGCACTTTGTTACTGGCTTTTTTGAGA
CTGCTGAATACCAAAGGAGAAATCCAAATAGATGGTGTGTCTTGGGATTCAATTACTTTG
CAACAATGGAGGAAGGCCTTTGGAGTCATACCACAGAAAGTATTCATCTTTTCTGGAACA
TTTAGAAAAAACTTGGACCCCTATGGACAGTGGAGTGATCAAGAAATATGGAAAGTTGCA
GATGAGGTCGGACTCAGAGCTGTGATAGAGCAGTTTCCTGGGAAGCTTGATTTTGTCCTT
GTGGATGGGGGTTGTGTTCTAAGCCACGGCCACAAGCAGTTGATGTGCTTGGCCAGATCT
GTTCTCAGTAAAGCAAAGATCTTGCTGCTTGATGAACCCAGTGCTCATTTGGATCCAATA
ACATACCAGATCATTCGAAGAACCCTAAAACAAGCATTTGCTAATTGCACAGTAATCCTC
TCTGAACACAGGATAGAAGCAATGTTGGAATGTCAACGATTTTTTGTCATAGAGGAGAAC
AAGGTGCGGCAGTATGATTCCATCCAGAGGATGCTGAGCGAGAAGAGCCTCTTCCGGCAA
GCCATCAGCCCCGCAGACCGCTTGAAGCTCTTGCCCCACCGGAACTCGAGCAGGCAGAGG
TCTCGGTCCAACATCGCGGCTCTGAAGGAGGAGACAGAAGAAGAGGTGCAAGAAACAAAG
CTTTAG
Enzyme 4 GenBank Gene ID M76128 Link Image
Enzyme 4 GeneCard ID CFTR Link Image
Enzyme 4 GenAtlas ID Not Available
Enzyme 4 HGNC ID Not Available
Enzyme 4 Chromosome Location Chromosome:7
Enzyme 4 Locus 7q31.2
Enzyme 4 SNPs SNPJam Report Link Image
Enzyme 4 General References
  1. [PubMed Link Image]
Enzyme 4 Metabolite References Not Available
Enzyme 5 [top]
Enzyme 5 ID 139
Enzyme 5 Name Serine/threonine-protein phosphatase dullard
Enzyme 5 Synonyms Not Available
Enzyme 5 Gene Name DULLARD
Enzyme 5 Protein Sequence >Serine/threonine-protein phosphatase dullard
MMRTQCLLGLRTFVAFAAKLWSFFIYLLRRQIRTVIQYQTVRYDILPLSPVSRNRLSQVK
RKILVLDLDETLIHSHHDGVLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEV
VSQWYELVVFTASMEIYGSAVADKLDNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLS
SIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQ
HRLW
Enzyme 5 Number of Residues 244
Enzyme 5 Molecular Weight 28392.7
Enzyme 5 Theoretical pI 10.19
Enzyme 5 GO Classification
Function
Process
Component
Enzyme 5 General Function Involved in protein serine/threonine phosphatase activity
Enzyme 5 Specific Function Serine/threonine phosphatase which may be required for proper nuclear membrane morphology. Involved in LPIN1 dephosphorylation. May antagonize BMP signaling
Enzyme 5 Pathways Not Available
Enzyme 5 Reactions Not Available
Enzyme 5 Pfam Domain Function
Enzyme 5 Signals
  • None
Enzyme 5 Transmembrane Regions
  • 7-29
Enzyme 5 Essentiality Not Available
Enzyme 5 GenBank ID Protein 92096691 Link Image
Enzyme 5 UniProtKB/Swiss-Prot ID Q1RMV9 Link Image
Enzyme 5 UniProtKB/Swiss-Prot Entry Name DULRD_BOVIN Link Image
Enzyme 5 PDB ID Not Available
Enzyme 5 Cellular Location Not Available
Enzyme 5 Gene Sequence >735 bp
ATGATGAGGACGCAGTGTCTGCTGGGGCTGCGCACGTTCGTGGCCTTCGCCGCCAAGCTC
TGGAGCTTCTTCATTTACCTTTTGAGGAGGCAGATCCGCACGGTAATTCAGTACCAAACT
GTTCGATATGACATCCTTCCCTTATCTCCTGTGTCCCGGAATCGGCTAAGCCAGGTGAAG
AGGAAGATCCTGGTGCTGGATCTGGATGAGACACTTATTCACTCCCATCATGATGGGGTC
CTGAGGCCCACAGTCCGGCCTGGAACGCCTCCTGACTTCATTCTCAAGGTGGTAATAGAC
AAACATCCCGTCCGGTTTTTTGTACATAAGAGGCCCCATGTGGATTTCTTCTTGGAAGTG
GTGAGCCAGTGGTACGAGTTGGTGGTGTTCACAGCAAGCATGGAGATTTATGGCTCTGCT
GTGGCAGATAAACTGGATAATAGCAGAAGCATTCTCAAGAGAAGATACTACAGACAACAC
TGCACTTTGGAATTGGGCAGCTACATCAAGGACCTCTCTGTGGTCCACAGTGACCTCTCC
AGCATTGTGATCCTGGATAACTCCCCAGGGGCTTACAGGAGCCATCCAGACAATGCCATC
CCCATCAAATCCTGGTTCAGTGATCCCAGTGATACCGCCCTTCTCAACCTGCTTCCAATG
CTGGATGCCCTCAGGTTCACCGCTGATGTTCGTTCTGTGCTGAGCCGAAACCTTCACCAA
CATAGGCTCTGGTGA
Enzyme 5 GenBank Gene ID BC114677 Link Image
Enzyme 5 GeneCard ID DULLARD Link Image
Enzyme 5 GenAtlas ID Not Available
Enzyme 5 HGNC ID Not Available
Enzyme 5 Chromosome Location Chromosome:1
Enzyme 5 Locus 17p13
Enzyme 5 SNPs SNPJam Report Link Image
Enzyme 5 General References Not Available
Enzyme 5 Metabolite References Not Available
Enzyme 6 [top]
Enzyme 6 ID 140
Enzyme 6 Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Enzyme 6 Synonyms
  1. 6PF-2-K/Fru-2,6-P2ASE liver isozyme
  2. 6-phosphofructo-2-kinase
  3. Fructose-2,6-bisphosphatase
Enzyme 6 Gene Name PFKFB1
Enzyme 6 Protein Sequence >6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
MSQEMGELTQTRLQKIWIPHNNGNSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
KLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALLIRKQCALAALKDVHSYL
SHEEGRVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPDVIAENIRQVKLGSPD
YIDCDREKVLEDFLKRIECYEVNYQPLDDELDSHLSYIKIFDVGTRYMVNRVQDHIQSRT
VYYLMNIHVTPRSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIQSQGISSLK
VGTSHMKRTIQTAEALGLPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY
RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH
TVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
Enzyme 6 Number of Residues 471
Enzyme 6 Molecular Weight 54656.8
Enzyme 6 Theoretical pI 6.51
Enzyme 6 GO Classification
Function
Process
Component
Enzyme 6 General Function Carbohydrate transport and metabolism
Enzyme 6 Specific Function Synthesis and degradation of fructose 2,6-bisphosphate
Enzyme 6 Pathways Not Available
Enzyme 6 Reactions Not Available
Enzyme 6 Pfam Domain Function
Enzyme 6 Signals
  • None
Enzyme 6 Transmembrane Regions
  • None
Enzyme 6 Essentiality Not Available
Enzyme 6 GenBank ID Protein 163518 Link Image
Enzyme 6 UniProtKB/Swiss-Prot ID P49872 Link Image
Enzyme 6 UniProtKB/Swiss-Prot Entry Name F261_BOVIN Link Image
Enzyme 6 PDB ID 1K6M Link Image
Enzyme 6 PDB File Show
Enzyme 6 3D Structure
Enzyme 6 Cellular Location Not Available
Enzyme 6 Gene Sequence >1416 bp
ATGTCTCAAGAGATGGGAGAGCTCACCCAAACCAGATTGCAGAAGATCTGGATTCCACAC
AACAACGGCAACAGCAGGCTTCAACGGAGGAGGGGCTCATCCATACCACAGTTTACAAAT
TCCCCCACAATGGTGATCATGGTGGGTTTACCAGCTCGAGGAAAGACCTACATCTCAACA
AAGCTCACACGCTATCTCAACTGGATAGGAACACCAACTAAAGTGTTTAATTTAGGCCAA
TATCGACGAGAGGCAGTGAGCTACAAGAACTACGAATTCTTTCTTCCCGACAACATGGAG
GCCCTACTTATCAGGAAGCAGTGTGCCCTAGCAGCCCTGAAAGATGTTCATAGCTATCTC
AGCCATGAGGAAGGTCGTGTTGCAGTTTTTGATGCCACCAACACTACCAGAGAACGACGG
TCACTGATTCTGCAGTTTGCTAAAGAACATGGTTACAAGGTCTTTTTCATTGAGTCCATT
TGTAATGACCCTGACGTCATTGCAGAAAACATCAGGCAAGTGAAACTTGGCAGTCCTGAT
TATATAGACTGTGATCGTGAAAAGGTTCTGGAAGATTTTCTAAAGAGAATAGAGTGCTAT
GAGGTCAACTACCAACCCTTGGATGATGAACTGGATAGCCACCTGTCCTACATCAAGATC
TTCGACGTGGGCACACGCTACATGGTGAATCGTGTGCAGGACCATATCCAGAGCCGCACA
GTCTACTATCTCATGAACATTCACGTCACACCCCGCTCCATCTACCTATGCCGGCACGGT
GAGAGTGAACTCAACCTCAGAGGCCGCATTGGAGGTGACTCTGGCCTCTCAGCTCGGGGC
AAGCAGTATGCCTATGCCCTGGCCAATTTCATTCAGTCCCAGGGTATCAGCTCACTGAAG
GTTGGGACCAGCCACATGAAGAGGACTATCCAGACAGCTGAAGCCTTAGGACTTCCCTAT
GAGCAATGGAAGGCCCTGAATGAGATTGATGCGGGTGTCTGTGAGGAGATGACCTATGAA
GAAATCCAAGAACACTACCCTGAAGAATTTGCACTGCGAGACCAAGATAAATACCGCTAC
CGCTATCCTAAGGGAGAGTCTTACGAGGATCTGGTCCAGCGTCTGGAGCCAGTTATAATG
GAGCTAGAACGGCAGGAAAATGTATTGGTGATCTGCCATCAGGCTGTCATGCGGTGCCTC
CTGGCCTACTTTCTGGACAAGAGCTCAGATGAGTTGCCTTATCTCAAGTGCCCTCTCCAC
ACAGTGCTCAAACTTACACCTGTGGCTTATGGCTGCAAAGTGGAGTCCATCTACCTGAAT
GTGGAGGCTGTAAACACACATCGGGAGAAACCTGAGAATGTGGACATCACCCGGGAACCT
GAAGAAGCCCTGGACACTGTTCCTGCCCACTACTGA
Enzyme 6 GenBank Gene ID M64323 Link Image
Enzyme 6 GeneCard ID PFKFB1 Link Image
Enzyme 6 GenAtlas ID Not Available
Enzyme 6 HGNC ID Not Available
Enzyme 6 Chromosome Location Not Available
Enzyme 6 Locus Xp11.21
Enzyme 6 SNPs SNPJam Report Link Image
Enzyme 6 General References
  1. [PubMed Link Image]
Enzyme 6 Metabolite References Not Available
Enzyme 7 [top]
Enzyme 7 ID 141
Enzyme 7 Name Proto-oncogene tyrosine-protein kinase Fyn
Enzyme 7 Synonyms
  1. p59-Fyn
Enzyme 7 Gene Name FYN
Enzyme 7 Protein Sequence >Proto-oncogene tyrosine-protein kinase Fyn
MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHGAGGQG
LTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWW
EARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESET
TKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCC
RLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKT
LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGR
ALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY
TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE
RGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL
Enzyme 7 Number of Residues 537
Enzyme 7 Molecular Weight 60717.4
Enzyme 7 Theoretical pI 6.65
Enzyme 7 GO Classification
Function
Process
Component
Enzyme 7 General Function Involved in ATP binding
Enzyme 7 Specific Function Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC. May phosphorylate and regulate CLIC5
Enzyme 7 Pathways Not Available
Enzyme 7 Reactions Not Available
Enzyme 7 Pfam Domain Function
Enzyme 7 Signals
  • None
Enzyme 7 Transmembrane Regions
  • None
Enzyme 7 Essentiality Not Available
Enzyme 7 GenBank ID Protein 117306509 Link Image
Enzyme 7 UniProtKB/Swiss-Prot ID A0JNB0 Link Image
Enzyme 7 UniProtKB/Swiss-Prot Entry Name FYN_BOVIN Link Image
Enzyme 7 PDB ID Not Available
Enzyme 7 Cellular Location Not Available
Enzyme 7 Gene Sequence >1614 bp
ATGGGCTGTGTGCAATGTAAGGACAAAGAAGCAACAAAACTGACGGAGGAGAGGGATGGC
AGTCTGAACCAGAGCTCCGGGTACCGCTATGGTACAGACCCCACTCCTCAGCACTACCCC
AGCTTCGGTGTGACCTCCATCCCGAACTACAACAACTTCCACGGGGCCGGGGGCCAAGGA
CTCACCGTCTTTGGGGGTGTGAACTCTTCGTCTCATACTGGGACCTTGCGAACAAGAGGA
GGAACAGGAGTGACCCTGTTTGTGGCCCTTTATGACTATGAAGCACGGACGGAAGATGAC
CTGAGTTTTCACAAAGGAGAAAAATTTCAAATATTGAACAGCTCGGAAGGAGATTGGTGG
GAAGCACGCTCCTTGACAACTGGAGAGACGGGTTACATTCCCAGCAATTATGTGGCTCCA
GTTGACTCCATCCAGGCAGAAGAGTGGTACTTTGGAAAACTCGGCCGGAAAGATGCTGAG
CGACAGCTTTTGTCCTTTGGAAACCCACGGGGTACCTTTCTTATCCGTGAGAGTGAAACC
ACCAAAGGTGCCTATTCACTTTCTATCCGAGACTGGGATGATATGAAAGGAGACCATGTC
AAACATTATAAAATTCGCAAACTTGACAACGGTGGATACTATATTACCACCCGGGCCCAA
TTTGAAACCCTTCAGCAGCTTGTACAACATTACTCAGAGAGAGCTGCAGGCCTCTGCTGC
CGCCTAGTAGTTCCCTGTCACAAAGGGATGCCACGGCTTACCGATCTGTCTGTCAAAACC
AAAGATGTCTGGGAAATCCCTCGAGAATCCCTGCAGTTGATCAAGAGACTGGGAAATGGG
CAGTTTGGGGAAGTATGGATGGGTACCTGGAATGGAAACACAAAAGTAGCCATAAAGACT
CTTAAACCAGGCACAATGTCCCCTGAATCATTCCTTGAGGAGGCGCAGATCATGAAGAAG
TTGAAGCACGACAAACTGGTCCAGCTATATGCCGTGGTGTCCGAGGAGCCCATCTACATC
GTCACCGAGTATATGAATAAAGGAAGTTTACTCGATTTCTTGAAAGATGGGGAAGGAAGG
GCTCTGAAATTACCAAATCTCGTGGACATGGCAGCACAGGTTGCCGCGGGAATGGCGTAC
ATCGAGCGCATGAATTACATCCACAGAGACCTGCGGTCAGCAAACATTCTCGTGGGGAAT
GGACTAATTTGCAAGATCGCCGACTTCGGATTGGCCAGGTTGATCGAGGACAATGAGTAC
ACAGCAAGACAAGGCGCCAAGTTCCCCATCAAGTGGACGGCCCCCGAAGCAGCCCTGTAC
GGGAGGTTCACAATCAAGTCTGACGTGTGGTCTTTTGGAATCTTACTCACAGAGCTGGTC
ACCAAAGGAAGAGTTCCGTACCCAGGCATGAACAACCGGGAGGTGCTGGAGCAGGTGGAG
CGCGGTTACAGGATGCCCTGTCCACAGGACTGCCCCATCTCCCTCCACGAGCTCATGATA
CACTGCTGGAAAAAGGACCCCGAAGAGCGGCCCACTTTCGAGTACCTGCAGGGCTTCCTG
GAAGACTACTTCACCGCAACAGAGCCTCAGTATCAACCCGGGGAAAACCTGTAA
Enzyme 7 GenBank Gene ID BC126591 Link Image
Enzyme 7 GeneCard ID FYN Link Image
Enzyme 7 GenAtlas ID Not Available
Enzyme 7 HGNC ID Not Available
Enzyme 7 Chromosome Location Chromosome:6
Enzyme 7 Locus 6q21
Enzyme 7 SNPs SNPJam Report Link Image
Enzyme 7 General References
  1. [PubMed Link Image]
Enzyme 7 Metabolite References Not Available
Enzyme 8 [top]
Enzyme 8 ID 142
Enzyme 8 Name [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
Enzyme 8 Synonyms
  1. Branched-chain alpha-ketoacid dehydrogenase kinase
  2. BCKD-kinase
  3. BCKDHKIN
Enzyme 8 Gene Name BCKDK
Enzyme 8 Protein Sequence >[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
MILASVLGSGPRGGPPLRPLLGPALSLRARSTSATDTHHVEMARERSKTVTSFYNQSAID
VAAEKPSVRLTPTMMLYSGRSQDGSHLLKSARYLQQELPVRIAHRIKGFRSLPFIIGCNP
TILHVHELYIRAFQKLTDFPPIKDQADEARYCQLVRQLLDDHKDVVTLLAEGLRESRKYI
EDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFVGIICTRLSPKKIIEKWVDFARR
LCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVI
TIANNDIDLVIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDLHSGGQS
GPMHGFGFGLPTSRAYAEYLGGSLRLQSLQGIGTDVYLRLRHIDGREESFRI
Enzyme 8 Number of Residues 412
Enzyme 8 Molecular Weight 46438.0
Enzyme 8 Theoretical pI 9.48
Enzyme 8 GO Classification
Function
Process
Component
Enzyme 8 General Function Signal transduction mechanisms
Enzyme 8 Specific Function Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex
Enzyme 8 Pathways Not Available
Enzyme 8 Reactions Not Available
Enzyme 8 Pfam Domain Function
Enzyme 8 Signals
  • None
Enzyme 8 Transmembrane Regions
  • None
Enzyme 8 Essentiality Not Available
Enzyme 8 GenBank ID Protein 86827669 Link Image
Enzyme 8 UniProtKB/Swiss-Prot ID Q2KJG8 Link Image
Enzyme 8 UniProtKB/Swiss-Prot Entry Name BCKD_BOVIN Link Image
Enzyme 8 PDB ID 1GKZ Link Image
Enzyme 8 PDB File Show
Enzyme 8 3D Structure
Enzyme 8 Cellular Location Not Available
Enzyme 8 Gene Sequence >1239 bp
ATGATACTGGCTTCGGTGCTGGGGAGCGGACCCCGGGGCGGGCCACCCCTCCGGCCTCTC
TTGGGGCCCGCACTCTCGCTCCGGGCCCGCTCCACATCAGCCACTGATACCCACCATGTG
GAAATGGCACGGGAGCGCTCTAAGACCGTCACCTCCTTTTACAACCAGTCAGCCATTGAC
GTCGCAGCGGAGAAGCCTTCAGTCCGCCTCACTCCAACCATGATGCTCTATTCAGGCCGC
TCCCAGGATGGCAGTCACCTCCTGAAAAGTGCCCGCTACTTGCAGCAGGAGTTGCCAGTG
AGGATCGCTCACCGCATCAAGGGCTTCCGCAGCCTTCCTTTCATCATTGGCTGCAACCCC
ACCATACTGCACGTGCACGAGCTGTACATCCGTGCCTTCCAGAAGCTGACAGACTTCCCT
CCGATCAAGGACCAGGCGGATGAGGCCCGATACTGCCAGCTGGTGCGACAGCTGTTGGAT
GACCACAAGGACGTGGTGACCCTCTTAGCGGAAGGCCTGCGTGAGAGCCGGAAGTACATA
GAGGATGAGAAGCTCGTCCGTTACTTCTTAGACAAGACGTTGACTTCAAGGCTTGGGATC
CGTATGTTGGCCACCCACCATCTGGCACTACATGAGGACAAGCCCGACTTTGTTGGCATC
ATCTGCACTCGCCTGTCACCGAAGAAGATTATTGAAAAGTGGGTGGACTTTGCCAGACGC
CTGTGTGAGCACAAGTATGGCAATGCACCCCGAGTCCGCATCAACGGACACGTGGCTGCC
CGTTTCCCCTTCATCCCAATGCCACTGGACTACATCCTACCTGAGCTGCTCAAGAACGCC
ATGAGAGCCACAATGGAGAGTCACCTCGACACTCCCTACAATGTCCCAGATGTCGTCATC
ACCATCGCCAACAATGATATCGATCTCGTCATCAGGATTTCAGACCGGGGCGGGGGAATT
GCTCACAAAGACCTGGATCGGGTGATGGACTACCACTTCACTACAGCTGAGGCCAGCACC
CAGGACCCCCGGATCAGCCCCCTCTTTGGCCACCTGGACTTGCACAGTGGTGGCCAGTCA
GGACCCATGCACGGCTTTGGCTTCGGGCTGCCCACTTCGCGGGCCTACGCAGAGTACCTC
GGTGGTTCCCTTCGGCTGCAGTCGCTGCAGGGCATTGGCACAGATGTCTACCTACGGCTC
CGTCACATCGATGGCCGGGAAGAAAGCTTCCGCATCTGA
Enzyme 8 GenBank Gene ID BC105352 Link Image
Enzyme 8 GeneCard ID BCKDK Link Image
Enzyme 8 GenAtlas ID Not Available
Enzyme 8 HGNC ID Not Available
Enzyme 8 Chromosome Location Chromosome:1
Enzyme 8 Locus 16p11.2
Enzyme 8 SNPs SNPJam Report Link Image
Enzyme 8 General References Not Available
Enzyme 8 Metabolite References Not Available
Enzyme 9 [top]
Enzyme 9 ID 143
Enzyme 9 Name Insulin-like growth factor 1 receptor
Enzyme 9 Synonyms
  1. Insulin-like growth factor I receptor
  2. IGF-I receptor
  3. CD221 antigen
  4. Insulin-like growth factor 1 receptor alpha chain
  5. Insulin-like growth factor 1 receptor beta chain
  6. Fragment
Enzyme 9 Gene Name IGF1R
Enzyme 9 Protein Sequence >Insulin-like growth factor 1 receptor
NAIFVPRPERKRREVMQIANTTMSSRSRNTTVLDTYNITDPEELETEYPFFESRVDNKER
TVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENS
IFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQA
TSLSGNGSWTDPVFFYVQAKTTYENFIHLMIALPIAVLLIVGGLVIMLYVFHRKRNSSRL
GNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPE
TRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDL
KSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDF
TVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIAT
LAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSVK
DEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSASLPLPDRHSGHKAEN
GPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
Enzyme 9 Number of Residues 640
Enzyme 9 Molecular Weight 72510.9
Enzyme 9 Theoretical pI 5.08
Enzyme 9 GO Classification
Function
Process
Component
Enzyme 9 General Function Involved in ATP binding
Enzyme 9 Specific Function This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1
Enzyme 9 Pathways Not Available
Enzyme 9 Reactions Not Available
Enzyme 9 Pfam Domain Function
Enzyme 9 Signals
  • None
Enzyme 9 Transmembrane Regions
  • 209-232
Enzyme 9 Essentiality Not Available
Enzyme 9 GenBank ID Protein 434 Link Image
Enzyme 9 UniProtKB/Swiss-Prot ID Q05688 Link Image
Enzyme 9 UniProtKB/Swiss-Prot Entry Name IGF1R_BOVIN Link Image
Enzyme 9 PDB ID 1M7N Link Image
Enzyme 9 PDB File Show
Enzyme 9 3D Structure
Enzyme 9 Cellular Location Not Available
Enzyme 9 Gene Sequence Not Available
Enzyme 9 GenBank Gene ID X54980 Link Image
Enzyme 9 GeneCard ID IGF1R Link Image
Enzyme 9 GenAtlas ID Not Available
Enzyme 9 HGNC ID Not Available
Enzyme 9 Chromosome Location Chromosome:1
Enzyme 9 Locus 15q26.3
Enzyme 9 SNPs SNPJam Report Link Image
Enzyme 9 General References
  1. [PubMed Link Image]
Enzyme 9 Metabolite References Not Available
Enzyme 10 [top]
Enzyme 10 ID 144
Enzyme 10 Name Dual specificity protein phosphatase 14
Enzyme 10 Synonyms Not Available
Enzyme 10 Gene Name DUSP14
Enzyme 10 Protein Sequence >Dual specificity protein phosphatase 14
MSSRGHSTLPRTLMAPRMISEGDLGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT
IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT
LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI
VPDVYEKESRHLLPYWGI
Enzyme 10 Number of Residues 198
Enzyme 10 Molecular Weight 22236.7
Enzyme 10 Theoretical pI 9.93
Enzyme 10 GO Classification
Function
Process
Component
Enzyme 10 General Function Signal transduction mechanisms
Enzyme 10 Specific Function Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases
Enzyme 10 Pathways Not Available
Enzyme 10 Reactions Not Available
Enzyme 10 Pfam Domain Function
Enzyme 10 Signals
  • None
Enzyme 10 Transmembrane Regions
  • None
Enzyme 10 Essentiality Not Available
Enzyme 10 GenBank ID Protein 109658275 Link Image
Enzyme 10 UniProtKB/Swiss-Prot ID Q17QM8 Link Image
Enzyme 10 UniProtKB/Swiss-Prot Entry Name DUS14_BOVIN Link Image
Enzyme 10 PDB ID Not Available
Enzyme 10 Cellular Location Not Available
Enzyme 10 Gene Sequence >597 bp
ATGAGCTCCAGAGGTCACAGCACGCTCCCCCGGACTCTCATGGCCCCCCGGATGATTTCT
GAGGGAGACCTGGGAGGCATTGCGCAGATCACCTCCTCGCTCTTCCTGGGCAGAGGCAGC
GTAGCCTCCAACCGGCACCTCCTCCAGGCTCGCGGCATCACCTGCATTGTGAACGCTACC
ATCGAGATCCCCAATTTCAACTGGCCCCAGTTTGAATACGTTAAAGTGCCTCTGGCGGAC
ATGCCTCACGCCCCCATTGGACTGTACTTTGACACCGTGGCCGACAAGATCCACAGCGTG
AGCCGGAAACACGGGGCCACCCTGGTGCACTGTGCTGCGGGGGTCAGCCGCTCGGCCACG
CTCTGCATCGCGTACCTGATGAAATTCCACAACGTGTGCCTGCTGGAGGCCTACAACTGG
GTGAAAGCCCGGAGGCCCGTCATCAGGCCCAACGTCGGCTTCTGGAGGCAGCTGATAGAC
TACGAGCGGCAGCTTTTTGGGAAGTCGACAGTTAAGATGGTACAGACACCGTACGGCATA
GTGCCGGACGTTTACGAGAAGGAGTCCCGACACCTGCTGCCTTACTGGGGGATCTGA
Enzyme 10 GenBank Gene ID BC118267 Link Image
Enzyme 10 GeneCard ID DUSP14 Link Image
Enzyme 10 GenAtlas ID Not Available
Enzyme 10 HGNC ID Not Available
Enzyme 10 Chromosome Location Chromosome:1
Enzyme 10 Locus 17q12
Enzyme 10 SNPs SNPJam Report Link Image
Enzyme 10 General References Not Available
Enzyme 10 Metabolite References Not Available
Enzyme 11 [top]
Enzyme 11 ID 145
Enzyme 11 Name Sodium/potassium-transporting ATPase subunit alpha-1
Enzyme 11 Synonyms
  1. Sodium pump subunit alpha-1
  2. Na(+)/K(+) ATPase alpha-1 subunit
Enzyme 11 Gene Name ATP1A1
Enzyme 11 Protein Sequence >Sodium/potassium-transporting ATPase subunit alpha-1
MGKGVGRDKYEPAAVSEHGDKKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRG
LTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAVLCFLAYGIQAATE
EEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINA
EEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNI
AFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFL
GVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALS
RIAGLCNRAVFQANQDNLPILKRAVAGDASESALLKCIEVCCGSVKEMRERYTKIVEIPF
NSTNKYQLSIHKNANAGEPRHLLVMKGAPERILDRCSSILIHGKEQPLDEELKDAFQNAY
LELGGLGERVLGFCHLLLPDEQFPEGFQFDTDDVNFPVDNLCFVGLISMIDPPRAAVPDA
VGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDARA
CVVHGSDLKDMTPEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDS
PALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTS
NIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPQTD
KLVNERLISMAYGQIGMIQALGGFFTYFVIMAENGFLPNHLLGIRVTWDDRWINDVEDSY
GQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEET
ALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETY
Y
Enzyme 11 Number of Residues 1021
Enzyme 11 Molecular Weight 112641.7
Enzyme 11 Theoretical pI 5.19
Enzyme 11 GO Classification
Function
Process
Component
Enzyme 11 General Function Inorganic ion transport and metabolism
Enzyme 11 Specific Function This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients
Enzyme 11 Pathways Not Available
Enzyme 11 Reactions Not Available
Enzyme 11 Pfam Domain Function
Enzyme 11 Signals
  • None
Enzyme 11 Transmembrane Regions
  • 86-106 130-150 287-306 319-336 771-790 801-821 842-864 917-936 950-968 984-1004
Enzyme 11 Essentiality Not Available
Enzyme 11 GenBank ID Protein 115305284 Link Image
Enzyme 11 UniProtKB/Swiss-Prot ID Q08DA1 Link Image
Enzyme 11 UniProtKB/Swiss-Prot Entry Name AT1A1_BOVIN Link Image
Enzyme 11 PDB ID 1MO8 Link Image
Enzyme 11 PDB File Show
Enzyme 11 3D Structure
Enzyme 11 Cellular Location Not Available
Enzyme 11 Gene Sequence >3066 bp
ATGGGGAAGGGGGTTGGACGTGATAAATATGAACCGGCAGCTGTTTCAGAGCATGGGGAC
AAGAAAAAAGCCAAGAAAGAGAGGGATATGGACGAGCTGAAGAAAGAAGTTTCTATGGAT
GATCATAAACTTAGCCTTGATGAACTTCATCGCAAATATGGAACAGACTTGAGCCGAGGC
TTAACAACTGCTCGAGCTGCCGAGATCCTAGCCAGAGATGGACCCAACGCCCTCACGCCC
CCTCCCACGACCCCTGAATGGGTCAAGTTCTGTCGACAGCTGTTTGGGGGGTTCTCAATG
TTACTGTGGATTGGAGCAGTTCTTTGCTTCCTGGCCTATGGTATCCAAGCTGCTACAGAA
GAGGAACCTCAAAATGATAATCTGTACCTTGGTGTGGTGCTGTCTGCTGTCGTCATCATA
ACCGGGTGTTTCTCCTACTATCAAGAAGCTAAAAGCTCAAAGATCATGGAGTCCTTCAAA
AACATGGTTCCTCAGCAAGCCCTCGTGATTCGAAATGGTGAGAAAATGAGCATAAATGCG
GAAGAGGTTGTCGTCGGAGATCTGGTGGAAGTGAAAGGAGGGGATCGAATTCCTGCCGAT
CTCAGGATCATTTCTGCAAATGGCTGCAAGGTGGATAACTCCTCACTCACGGGAGAATCA
GAGCCACAGACCAGGTCTCCGGATTTCACCAATGAAAATCCCCTGGAGACACGGAACATT
GCCTTTTTTTCAACTAACTGTGTTGAAGGCACTGCACGTGGCATTGTCGTGTATACTGGG
GATCGAACCGTGATGGGCAGAATTGCCACGCTGGCTTCTGGGCTGGAGGGGGGCCAGACT
CCCATCGCTGCGGAAATTGAACATTTTATCCACATCATCACGGGTGTGGCTGTGTTCCTG
GGCGTGTCGTTCTTCATCCTTTCTCTGATCCTTGAGTACACCTGGCTGGAGGCTGTCATC
TTCCTCATCGGCATCATTGTAGCCAACGTGCCAGAGGGTTTGCTGGCCACCGTCACGGTG
TGCCTGACGCTGACTGCAAAGCGCATGGCCAGGAAAAACTGCTTAGTGAAGAACCTGGAG
GCTGTGGAGACCTTGGGATCCACGTCCACCATCTGCTCAGACAAAACTGGAACTCTGACC
CAGAACCGAATGACAGTGGCCCACATGTGGTTCGACAACCAAATCCACGAGGCGGACACG
ACAGAGAATCAGAGCGGTGTTTCATTTGACAAGACTTCGGCCACGTGGCTCGCTCTGTCC
AGAATTGCAGGTCTTTGTAACAGGGCCGTGTTTCAGGCTAACCAGGATAACCTGCCTATC
CTGAAGCGGGCTGTAGCGGGTGATGCCTCAGAGTCTGCGCTCCTGAAGTGCATTGAGGTG
TGCTGCGGTTCTGTGAAGGAGATGAGAGAGAGATACACCAAGATCGTCGAGATCCCATTC
AACTCCACCAACAAGTACCAGTTATCCATCCACAAGAACGCCAATGCAGGTGAGCCCCGG
CACCTACTGGTGATGAAAGGTGCCCCAGAAAGGATCTTGGACCGCTGCAGCTCCATCCTC
ATCCATGGCAAGGAGCAGCCCCTGGACGAGGAGCTGAAGGACGCTTTTCAGAATGCCTAC
CTGGAGCTGGGTGGCCTCGGAGAGCGTGTGCTGGGTTTTTGCCACTTGCTGCTGCCAGAT
GAGCAGTTTCCTGAAGGCTTCCAGTTTGACACCGACGATGTGAACTTCCCTGTTGATAAT
CTCTGCTTCGTGGGACTCATCTCCATGATTGACCCACCACGGGCTGCTGTCCCAGATGCT
GTGGGCAAATGCCGAAGTGCTGGAATCAAGGTCATCATGGTCACCGGAGACCATCCCATC
ACTGCCAAAGCCATTGCCAAAGGTGTGGGGATCATCTCAGAAGGTAATGAGACTGTAGAA
GACATTGCTGCCCGCCTCAACATCCCAGTGAGCCAGGTGAACCCCAGGGATGCCCGGGCC
TGCGTGGTGCATGGAAGTGATCTGAAGGACATGACTCCCGAGCAGCTGGATGACATCTTG
AAGTACCACACAGAGATTGTGTTCGCCAGGACCTCTCCGCAGCAGAAGCTCATCATTGTG
GAAGGCTGCCAGAGACAGGGTGCCATCGTGGCTGTAACTGGAGACGGTGTCAATGACTCC
CCGGCTTTGAAGAAGGCAGACATTGGGGTTGCCATGGGGATTGCAGGCTCAGACGTGTCT
AAGCAAGCTGCTGACATGATTCTCCTAGATGACAACTTTGCCTCAATTGTGACTGGAGTA
GAGGAAGGTCGTCTGATCTTTGATAACTTGAAGAAATCCATTGCTTATACCCTCACCAGT
AACATTCCTGAGATTACCCCCTTCCTGATATTTATTATTGCAAACATTCCACTCCCTCTG
GGGACCGTCACCATCCTCTGCATCGACTTGGGAACGGACATGGTCCCTGCTATCTCCTTG
GCTTATGAGCAGGCTGAGAGCGACATCATGAAGAGGCAGCCCAGAAACCCCCAGACGGAC
AAACTCGTGAACGAGCGGCTGATCAGCATGGCCTATGGACAGATTGGTATGATCCAGGCC
CTGGGGGGCTTCTTCACTTACTTTGTTATCATGGCTGAGAACGGCTTCCTCCCAAATCAC
CTGCTGGGCATCCGAGTGACCTGGGATGACCGTTGGATCAACGATGTGGAGGACAGCTAT
GGGCAGCAGTGGACCTATGAACAGAGGAAGATTGTGGAGTTCACCTGCCACACGGCCTTC
TTTGTCAGTATCGTGGTGGTGCAGTGGGCTGACCTGGTCATCTGCAAGACCAGGAGGAAT
TCTGTCTTCCAGCAGGGGATGAAGAACAAGATCTTAATATTTGGCCTCTTTGAAGAGACA
GCCCTTGCTGCTTTCCTTTCCTACTGCCCTGGAATGGGTGTTGCCCTGAGGATGTATCCC
CTCAAACCTACCTGGTGGTTCTGTGCCTTCCCCTACTCTCTTCTCATCTTCGTGTATGAC
GAAGTCCGGAAGCTCATCATCAGGCGACGTCCTGGCGGTTGGGTGGAGAAGGAGACCTAC
TACTAG
Enzyme 11 GenBank Gene ID BC123864 Link Image
Enzyme 11 GeneCard ID ATP1A1 Link Image
Enzyme 11 GenAtlas ID Not Available
Enzyme 11 HGNC ID Not Available
Enzyme 11 Chromosome Location Chromosome:1
Enzyme 11 Locus 1p21
Enzyme 11 SNPs SNPJam Report Link Image
Enzyme 11 General References Not Available
Enzyme 11 Metabolite References Not Available
Enzyme 12 [top]
Enzyme 12 ID 146
Enzyme 12 Name Activin receptor type-2A
Enzyme 12 Synonyms
  1. Activin receptor type IIA
  2. ACTR-IIA
Enzyme 12 Gene Name ACVR2A
Enzyme 12 Protein Sequence >Activin receptor type-2A
MGAAAKLAFAVFLISCSSGAILGRSETQECIFYNANWERDRTNRTGVESCYGDKDKRRHC
FATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNERFSYFPEM
EVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGP
PPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPG
MKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGL
AYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQV
GTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIG
QHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERIT
QMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
Enzyme 12 Number of Residues 513
Enzyme 12 Molecular Weight 57951.2
Enzyme 12 Theoretical pI 5.90
Enzyme 12 GO Classification
Function
Process
Component
Enzyme 12 General Function Involved in activin receptor activity
Enzyme 12 Specific Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A
Enzyme 12 Pathways Not Available
Enzyme 12 Reactions Not Available
Enzyme 12 Pfam Domain Function
Enzyme 12 Signals
  • 1-19
Enzyme 12 Transmembrane Regions
  • 136-161
Enzyme 12 Essentiality Not Available
Enzyme 12 GenBank ID Protein 393114 Link Image
Enzyme 12 UniProtKB/Swiss-Prot ID Q28043 Link Image
Enzyme 12 UniProtKB/Swiss-Prot Entry Name AVR2A_BOVIN Link Image
Enzyme 12 PDB ID Not Available
Enzyme 12 Cellular Location Not Available
Enzyme 12 Gene Sequence >1542 bp
ATGGGAGCCGCTGCAAAGTTGGCGTTTGCCGTCTTTCTTATCTCTTGTTCTTCAGGTGCT
ATACTTGGTAGATCAGAAACTCAGGAGTGTATTTTCTATAATGCTAATTGGGAAAGAGAT
AGAACGAATCGCACTGGTGTTGAATCCTGTTACGGTGACAAAGATAAACGGCGGCATTGT
TTTGCTACATGGAAGAATATTTCTGGTTCCATTGAAATAGTGAAGCAAGGTTGTTGGCTG
GATGATATCAACTGCTATGACAGGACTGATTGTATAGAAAAAAAAGATAGCCCTGAAGTA
TATTTTTGTTGCTGTGAGGGCAATATGTGTAACGAAAGGTTTTCTTATTTTCCGGAGATG
GAGGTCACACAGCCTACGTCGAATCCAGTAACTCCTAAGCCTCCCTATTACAACATCTTG
CTCTATTCTTTGGTGCCACTTATGTTAATTGCGGGGATTGTCATTTGTGCATTTTGGGTG
TACAGACATCATAAGATGGCTTACCCTCCTGTGCTCGTTCCAACTCAAGACCCAGGACCA
CCCCCACCTTCTCCATTACTAGGTTTGAAGCCATTACAGTTACTAGAAGTGAAAGCAAGA
GGAAGATTTGGTTGTGTGTGGAAAGCCCAGTTACTCAATGAATATGTGGCTGTGAAAATA
TTTCCAATACAGGATAAACAGTCATGGCAGAATGAATATGAAGTCTATAGTTTGCCTGGA
ATGAAGCATGAGAACATACTGCAGTTCATTGGTGCAGAGAAACGAGGCACCAGTGTTGAT
GTGGATCTTTGGCTAATCACAGCATTTCATGAAAAGGGTTCACTATCAGACTTTCTTAAG
GCTAATGTGGTCTCTTGGAATGAATTGTGTCATATTGCAGAAACCATGGCTAGAGGATTG
GCATATTTACATGAGGATATACCTGGCCTAAAAGATGGCCACAAACCCGCCATATCTCAC
AGGGACATCAAAAGTAAAAATGTGCTGTTGAAAAACAATCTGACAGCCTGCATTGCTGAC
TTTGGGTTGGCGTTGAAGTTTGAGGCTGGCAAGTCTGCAGGTGATACTCATGGACAGGTG
GGTACCCGAAGGTATATGGCTCCAGAGGTGTTAGAGGGTGCTATCAACTTCCAAAGGGAT
GCATTTTTGAGGATAGATATGTACGCCATGGGATTAGTCCTGTGGGAACTGGCTTCTCGC
TGTACTGCTGCAGATGGACCTGTAGATGAATACATGCTGCCATTTGAGGAAGAAATTGGC
CAGCATCCCTCTCTTGAAGACATGCAGGAAGTTGTTGTGCATAAAAAAAAGAGGCCTGTT
TTAAGAGATTATTGGCAGAAACATGCTGGAATGGCAATGCTCTGTGAAACGATAGAAGAA
TGTTGGGATCACGATGCAGAAGCCAGGTTATCAGCTGGATGTGTAGGTGAAAGAATTACT
CAGATGCAAAGACTAACAAATATCATTACCACAGAGGACATTGTAACAGTGGTCACGATG
GTGACAAATGTTGACTTTCCTCCCAAAGAATCTAGTCTATGA
Enzyme 12 GenBank Gene ID L21717 Link Image
Enzyme 12 GeneCard ID ACVR2A Link Image
Enzyme 12 GenAtlas ID Not Available
Enzyme 12 HGNC ID Not Available
Enzyme 12 Chromosome Location Chromosome:2
Enzyme 12 Locus 2q22.3
Enzyme 12 SNPs SNPJam Report Link Image
Enzyme 12 General References
  1. [PubMed Link Image]
Enzyme 12 Metabolite References Not Available
Enzyme 13 [top]
Enzyme 13 ID 147
Enzyme 13 Name Arsenical pump-driving ATPase
Enzyme 13 Synonyms
  1. Arsenite-translocating ATPase
  2. Arsenical resistance ATPase
  3. Arsenite-transporting ATPase
Enzyme 13 Gene Name ASNA1
Enzyme 13 Protein Sequence >Arsenical pump-driving ATPase
MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQ
LSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFE
EDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRLLNFP
TIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPE
QTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQA
KYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSAQ
Enzyme 13 Number of Residues 348
Enzyme 13 Molecular Weight 38792.4
Enzyme 13 Theoretical pI 4.54
Enzyme 13 GO Classification
Function
Process
Component
Enzyme 13 General Function Inorganic ion transport and metabolism
Enzyme 13 Specific Function Anion-transporting ATPase. Catalyzes the extrusion of arsenite
Enzyme 13 Pathways Not Available
Enzyme 13 Reactions Not Available
Enzyme 13 Pfam Domain Function
Enzyme 13 Signals
  • None
Enzyme 13 Transmembrane Regions
  • None
Enzyme 13 Essentiality Not Available
Enzyme 13 GenBank ID Protein 148744879 Link Image
Enzyme 13 UniProtKB/Swiss-Prot ID A5PJI5 Link Image
Enzyme 13 UniProtKB/Swiss-Prot Entry Name ARSA1_BOVIN Link Image
Enzyme 13 PDB ID Not Available
Enzyme 13 Cellular Location Not Available
Enzyme 13 Gene Sequence >1047 bp
ATGGCGGCAGGGGTGGCCGGGTGGGGGGTTGAGGCAGAGGAGTTCGAGGATGCCCCTGAT
GTGGAGCCGCTGGAGCCCACGCTTAGCAACATCATCGAGCAGCGCAGCCTTAAGTGGATC
TTCGTTGGGGGCAAAGGTGGAGTTGGCAAAACAACCTGCAGCTGCAGCCTAGCAGTCCAG
CTGTCCAAGGGGCGGGAGAGTGTTCTGATCATCTCCACCGACCCAGCCCACAACATCTCC
GATGCATTTGACCAGAAGTTCTCCAAGGTGCCTACCAAGGTCAAAGGCTATGACAACCTC
TTTGCCATGGAGATTGACCCCAGCCTGGGCGTGGCGGAGCTGCCAGACGAGTTCTTTGAA
GAGGACAACATGCTGAGCATGGGCAAAAAGATGATGCAAGAAGCTATGAGCGCATTCCCA
GGCATCGACGAGGCCATGAGCTACGCAGAGGTGATGAGGCTGGTGAAGGGCATGAACTTC
TCCGTGGTGGTGTTCGACACTGCGCCCACAGGCCACACGCTGAGGCTGCTCAACTTCCCC
ACCATCGTCGAGCGGGGGCTTGGCCGCCTCATGCAGATCAAGAACCAGATCAGCCCCTTC
ATCTCACAGATGTGCAACATGCTGGGCCTCGGCGACATGAACGCAGACCAGCTGGCCTCC
AAGCTAGAGGAGACGCTGCCTGTCATCCGCTCGGTCAGCGAGCAGTTCAAGGACCCTGAG
CAAACAACCTTCATCTGTGTGTGCATCGCGGAGTTCCTGTCCCTGTATGAAACCGAACGG
CTGATCCAGGAGCTGGCCAAGTGCAAGATTGACACGCACAACATCATCGTCAACCAGCTC
GTCTTCCCTGATCCCGAGAAGCCCTGCAAGATGTGTGAGGCCCGCCACAAGATCCAAGCC
AAGTACCTGGATCAGATGGAGGACCTATATGAAGACTTCCACATTGTGAAGCTGCCGCTG
CTGCCCCATGAGGTTCGGGGAGCAGACAAGGTCAACACCTTCTCCGCTCTCCTCCTGGAG
CCCTACAAGCCCCCCAGCGCGCAGTAG
Enzyme 13 GenBank Gene ID BC142125 Link Image
Enzyme 13 GeneCard ID ASNA1 Link Image
Enzyme 13 GenAtlas ID Not Available
Enzyme 13 HGNC ID Not Available
Enzyme 13 Chromosome Location Chromosome:1
Enzyme 13 Locus 19q13.3
Enzyme 13 SNPs SNPJam Report Link Image
Enzyme 13 General References Not Available
Enzyme 13 Metabolite References Not Available
Enzyme 14 [top]
Enzyme 14 ID 148
Enzyme 14 Name Glutamine synthetase
Enzyme 14 Synonyms
  1. GS
  2. Glutamate--ammonia ligase
Enzyme 14 Gene Name GLUL
Enzyme 14 Protein Sequence >Glutamine synthetase
MATSASSHLNKGIKQVYMALPQGDKVQAMYIWIDGTGEGLRCKTRTLDSEPKCIEELPEW
NFDGSSTFQSEGSNSDMYLVPAAMFRDPFRKDPNKLVFCEVFKYNRKPAETNLRHTCKRI
MDMVSNQRPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHY
RACLYAGIKIGGTNAEVMPAQWEFQIGPCEGIDMGDHLWVARFILHRVCEDFGVIATFDP
KPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRL
TGFHETSNINDFSAGVANRGASIRIPRTVGQEKKGYFEDRRPSANCDPFAVTEALIRTCL
LNETGDEPFQYKN
Enzyme 14 Number of Residues 373
Enzyme 14 Molecular Weight 42031.2
Enzyme 14 Theoretical pI 6.83
Enzyme 14 GO Classification
Function
Process
Component
Enzyme 14 General Function Amino acid transport and metabolism
Enzyme 14 Specific Function Essential for proliferation of fetal skin fibroblasts
Enzyme 14 Pathways Not Available
Enzyme 14 Reactions Not Available
Enzyme 14 Pfam Domain Function
Enzyme 14 Signals
  • None
Enzyme 14 Transmembrane Regions
  • None
Enzyme 14 Essentiality Not Available
Enzyme 14 GenBank ID Protein 73586743 Link Image
Enzyme 14 UniProtKB/Swiss-Prot ID P15103 Link Image
Enzyme 14 UniProtKB/Swiss-Prot Entry Name GLNA_BOVIN Link Image
Enzyme 14 PDB ID Not Available
Enzyme 14 Cellular Location Not Available
Enzyme 14 Gene Sequence >1122 bp
ATGGCCACCTCGGCGAGCTCCCACTTGAACAAAGGCATCAAGCAGGTGTACATGGCCCTA
CCTCAGGGTGATAAAGTCCAAGCTATGTACATCTGGATCGACGGTACTGGAGAAGGACTG
CGCTGCAAGACCCGAACCTTGGATTCTGAACCCAAGTGTATAGAAGAGTTGCCCGAGTGG
AATTTTGATGGCTCTAGTACTTTTCAGTCTGAAGGCTCCAACAGTGACATGTATCTTGTC
CCCGCTGCCATGTTTCGGGACCCTTTCCGCAAGGACCCCAACAAGCTGGTGTTCTGTGAA
GTCTTCAAGTACAACCGAAAGCCTGCAGAGACCAATTTAAGGCACACCTGTAAACGGATA
ATGGACATGGTGAGCAACCAGCGCCCCTGGTTTGGAATGGAGCAGGAATATACCCTCATG
GGCACTGATGGGCACCCCTTTGGTTGGCCTTCCAATGGCTTTCCTGGGCCCCAAGGTCCC
TACTACTGTGGTGTGGGAGCGGACAAGGCCTACGGCAGGGATATTGTGGAGGCTCACTAC
AGGGCCTGCTTGTACGCCGGCATCAAGATCGGGGGCACGAATGCCGAGGTCATGCCTGCA
CAGTGGGAATTCCAGATAGGACCCTGTGAAGGAATCGACATGGGCGATCATCTCTGGGTG
GCCCGTTTCATCTTGCATCGTGTGTGTGAAGACTTCGGAGTGATCGCCACCTTTGATCCT
AAGCCCATTCCTGGAAACTGGAATGGTGCTGGCTGCCACACCAACTTTAGCACCAAGGCC
ATGCGAGAGGAGAATGGTCTGAAGTACATTGAGGAGGCCATTGAGAAGCTAAGCAAGCGC
CACCAGTACCACATCCGAGCCTACGATCCCAAGGGGGGCCTGGACAACGCCCGGCGCCTA
ACTGGGTTCCACGAAACCTCCAACATCAACGACTTCTCTGCCGGCGTGGCCAACCGTGGT
GCTAGCATCCGCATCCCCCGGACTGTTGGCCAGGAGAAGAAGGGCTACTTCGAAGACCGT
CGCCCATCTGCCAACTGTGACCCCTTCGCCGTGACCGAAGCCCTCATCCGCACATGTCTT
CTGAACGAAACTGGCGACGAGCCCTTCCAGTACAAGAACTAA
Enzyme 14 GenBank Gene ID BC103099 Link Image
Enzyme 14 GeneCard ID GLUL Link Image
Enzyme 14 GenAtlas ID Not Available
Enzyme 14 HGNC ID Not Available
Enzyme 14 Chromosome Location Chromosome:1
Enzyme 14 Locus 1q31
Enzyme 14 SNPs SNPJam Report Link Image
Enzyme 14 General References
  1. [PubMed Link Image]
Enzyme 14 Metabolite References Not Available
Enzyme 15 [top]
Enzyme 15 ID 149
Enzyme 15 Name Cytosolic purine 5'-nucleotidase
Enzyme 15 Synonyms
  1. 5'-nucleotidase cytosolic II
  2. Cytosolic IMP/GMP-specific 5'-nucleotidase
Enzyme 15 Gene Name NT5C2
Enzyme 15 Protein Sequence >Cytosolic purine 5'-nucleotidase
MTTSWSDRLQNAADMPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVY
KSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLV
CAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTS
CETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMK
EVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGT
VLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTVCDLLGAKGKDILYIGDHIFGDILKS
KKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQ
RRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAA
HVLMPHESTVEHTHVDINEMESPLATRNRTSVDFKDTDYKRHQLTRSISEIKPPNLFPLA
PQEITHCHDEDDDEEEEEEE
Enzyme 15 Number of Residues 560
Enzyme 15 Molecular Weight 64840.1
Enzyme 15 Theoretical pI 6.15
Enzyme 15 GO Classification
Function
Process
Component
Enzyme 15 General Function Involved in 5'-nucleotidase activity
Enzyme 15 Specific Function May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides
Enzyme 15 Pathways Not Available
Enzyme 15 Reactions Not Available
Enzyme 15 Pfam Domain Function
Enzyme 15 Signals
  • None
Enzyme 15 Transmembrane Regions
  • None
Enzyme 15 Essentiality Not Available
Enzyme 15 GenBank ID Protein 2668557 Link Image
Enzyme 15 UniProtKB/Swiss-Prot ID O46411 Link Image
Enzyme 15 UniProtKB/Swiss-Prot Entry Name 5NTC_BOVIN Link Image
Enzyme 15 PDB ID Not Available
Enzyme 15 Cellular Location Not Available
Enzyme 15 Gene Sequence >1683 bp
ATGACAACCTCCTGGAGTGATCGGTTACAAAATGCAGCAGATATGCCTGCTAACATGGAT
AAACATGCCCTGAAAAAGTATCGGCGAGAAGCCTATCATCGGGTGTTTGTGAACCGGAGT
TTAGCCATGGAAAAAATAAAGTGTTTTGGGTTTGACATGGATTATACACTTGCTGTGTAC
AAGTCCCCGGAGTATGAGTCCCTTGGCTTTGAGCTTACTGTGGAGAGATTAGTTTCTATT
GGCTATCCTCAGGAACTTCTCAGCTTTGCATATGACTCTACATTCCCTACCAGGGGACTA
GTATTTGATACACTGTATGGAAATCTTTTGAAAGTTGATGCCTATGGAAACCTCTTGGTC
TGTGCACATGGATTTAACTTCATAAGGGGACCAGAAACTAGAGAGCAGTATCCAAATAAA
TTTATTCAACGAGATGACACTGAAAGATTTTACATTCTGAACACACTATTCAACCTACCA
GAGACCTACCTGTTGGCCTGCCTAGTAGATTTTTTTACTAATTGTCCCAGATACACCAGC
TGTGAAACAGGATTTAAAGATGGGGACCTCTTCATGTCTTACCGGAGTATGTTCCAGGAT
GTAAGAGACGCAGTTGACTGGGTTCATTACAAGGGTTCCCTTAAGGAAAAGACAGTTGAA
AATCTTGAGAAGTATGTAGTCAAAGATGGAAAACTGCCTTTGCTTCTGAGCCGGATGAAG
GAAGTAGGAAAAGTATTTCTTGCCACCAACAGTGACTATAAATATACAGATAAAATTATG
ACTTACCTGTTTGATTTCCCACATGGCCCCAAGCCTGGGAGCTCTCATCGGCCGTGGCAG
TCCTACTTTGACCTGATCTTGGTGGACGCACGGAAACCACTGTTCTTCGGAGAAGGCACA
GTACTGCGTCAGGTGGATACTAAAACTGGCAAGCTGAAAATTGGTACCTACACGGGCCCC
TTACAGCATGGCATCGTCTACTCTGGGGGTTCATCTGATACAGTTTGTGACCTGTTGGGA
GCCAAGGGCAAAGATATTTTGTATATTGGAGATCACATTTTTGGGGACATTTTAAAATCA
AAGAAACGGCAAGGGTGGCGAACTTTCTTGGTGATTCCTGAACTCGCACAGGAACTGCAT
GTCTGGACCGATAAGAGTTCACTTTTCGAAGAGCTTCAGAGCTTGGATATTTTCTTGGCT
GAACTCTACAAGCACCTTGACAGCAGCAGCAATGAGCGCCCAGATATCAGCTCCATCCAA
AGACGTATTAAGAAAGTAACTCACGACATGGACATGTGCTACGGGATGATGGGGAGCCTG
TTCCGCAGTGGCTCCCGGCAGACCCTTTTCGCCAGTCAGGTGATGCGCTATGCTGATCTC
TACGCAGCATCTTTCATCAACCTGCTGTACTACCCATTCAGCTACCTCTTCAGAGCGGCC
CACGTCTTGATGCCTCATGAGTCAACAGTGGAACACACACATGTAGATATCAATGAGATG
GAGTCCCCTCTCGCCACCCGGAACCGCACATCAGTGGATTTCAAAGATACCGACTACAAG
CGGCACCAACTGACACGGTCGATTAGTGAGATTAAGCCCCCCAACCTCTTCCCACTGGCC
CCCCAGGAAATTACACACTGCCATGACGAAGATGATGATGAGGAGGAAGAAGAGGAGGAG
TGA
Enzyme 15 GenBank Gene ID U73690 Link Image
Enzyme 15 GeneCard ID NT5C2 Link Image
Enzyme 15 GenAtlas ID Not Available
Enzyme 15 HGNC ID Not Available
Enzyme 15 Chromosome Location Chromosome:1
Enzyme 15 Locus 10q24.32-q24.33
Enzyme 15 SNPs SNPJam Report Link Image
Enzyme 15 General References
  1. [PubMed Link Image]
Enzyme 15 Metabolite References Not Available
Enzyme 16 [top]
Enzyme 16 ID 150
Enzyme 16 Name Fructose-1,6-bisphosphatase isozyme 2
Enzyme 16 Synonyms
  1. FBPase 2
  2. D-fructose-1,6-bisphosphate 1-phosphohydrolase 2
Enzyme 16 Gene Name FBP2
Enzyme 16 Protein Sequence >Fructose-1,6-bisphosphatase isozyme 2
MGDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLANLYGI
AGSVNVTGDEVKKLDVLSNALVINMLQSSYSTCVLVSEENKEAIITSKEKRGKYVVCFDP
LDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQPGRNIVAAGYALYGSATLVALSTGQ
GVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAP
YGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGT
QPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQAGR
Enzyme 16 Number of Residues 339
Enzyme 16 Molecular Weight 36766.9
Enzyme 16 Theoretical pI 7.81
Enzyme 16 GO Classification
Function
Process
Component
Enzyme 16 General Function Carbohydrate transport and metabolism
Enzyme 16 Specific Function D-fructose 1,6-bisphosphate + H(2)O = D- fructose 6-phosphate + phosphate
Enzyme 16 Pathways
  • Carbohydrate biosynthesis
  • gluconeogenesis
Enzyme 16 Reactions Not Available
Enzyme 16 Pfam Domain Function
Enzyme 16 Signals
  • None
Enzyme 16 Transmembrane Regions
  • None
Enzyme 16 Essentiality Not Available
Enzyme 16 GenBank ID Protein 86823226 Link Image
Enzyme 16 UniProtKB/Swiss-Prot ID Q2KJJ9 Link Image
Enzyme 16 UniProtKB/Swiss-Prot Entry Name F16P2_BOVIN Link Image
Enzyme 16 PDB ID Not Available
Enzyme 16 Cellular Location Not Available
Enzyme 16 Gene Sequence >1020 bp
ATGGGGGACAGAAGCCCCTTCGAAACGGACATGCTCACCCTGACCCGCTATGTTATGGAA
AAGGGGCGTCAGGCCAAAGGCACCGGGGAGCTCACGCAGCTGCTCAACTCCATGCTGACG
GCCATCAAAGCCATCTCCTCAGCTGTGCGTAAGGCGGGCCTGGCCAACCTGTACGGAATC
GCGGGAAGCGTGAACGTGACGGGGGATGAGGTGAAGAAACTGGACGTGTTATCCAATGCC
CTGGTGATCAACATGCTCCAGTCCTCCTACAGCACCTGCGTCCTGGTGTCGGAAGAGAAT
AAAGAAGCCATTATCACCTCCAAGGAGAAGAGGGGGAAATACGTGGTCTGCTTTGACCCT
CTGGACGGATCTTCCAACATTGACTGCCTGGCTTCCATTGGAACCATATTTGCCATCTAC
AGAAAGACCTCAGAGGATGAGCCTTCTGAAAAGGATGCCCTGCAGCCAGGTCGCAACATT
GTGGCTGCTGGCTATGCACTCTATGGAAGTGCAACCCTGGTGGCTCTTTCCACAGGGCAA
GGAGTGGACCTCTTCATGCTTGACCCAGCTCTTGGTGAATTTGTCTTGGTGGAAAAAGAT
GTCAAGATTAAAAAGAAAGGAAAGATTTACAGCCTCAACGAGGGCTATGCCAAGTATTTT
GATGCTGCCACCACAGAATATGTGCAGAAAAAGAAGTTTCCTGAGGACGGCAGTGCTCCC
TATGGGGCCAGGTACGTGGGCTCCATGGTGGCTGATGTGCACCGCACCCTTGTCTATGGA
GGGATCTTCCTGTACCCAGCAAACCAGAAAAGTCCGAAGGGCAAGCTCCGGCTCCTGTAT
GAGTGCAATCCTGTGGCCTACATCATCGAGCAGGCGGGAGGGCTGGCGACCACAGGCACC
CAACCCGTGCTGGACGTGAAGCCTGAAGCCATTCACCAACGAGTCCCCCTCATTCTAGGG
TCCCCAGAAGATGTACAGGAATATCTCACCTGTGTACAGAAAAATCAGGCAGGCAGGTAG
Enzyme 16 GenBank Gene ID BC102390 Link Image
Enzyme 16 GeneCard ID FBP2 Link Image
Enzyme 16 GenAtlas ID Not Available
Enzyme 16 HGNC ID Not Available
Enzyme 16 Chromosome Location Chromosome:9
Enzyme 16 Locus 9q22.3
Enzyme 16 SNPs SNPJam Report Link Image
Enzyme 16 General References Not Available
Enzyme 16 Metabolite References Not Available
Enzyme 17 [top]
Enzyme 17 ID 151
Enzyme 17 Name Acylphosphatase-1
Enzyme 17 Synonyms
  1. Acylphosphate phosphohydrolase 1
  2. Acylphosphatase, organ-common type isozyme
  3. Acylphosphatase, erythrocyte/testis isozyme
Enzyme 17 Gene Name ACYP1
Enzyme 17 Protein Sequence >Acylphosphatase-1
MSMAEGDTLISVDYEIFGKVQGVFFRKYTQAEGKKLGLVGWVQNTDQGTVQGQLQGPASK
VRHMQEWLETKGSPKSHIDRASFHNEKVIVKLDYTDFQIVK
Enzyme 17 Number of Residues 101
Enzyme 17 Molecular Weight 11432.0
Enzyme 17 Theoretical pI 8.94
Enzyme 17 GO Classification
Function
Process
Component
Enzyme 17 General Function Energy production and conversion
Enzyme 17 Specific Function An acylphosphate + H(2)O = a carboxylate + phosphate
Enzyme 17 Pathways Not Available
Enzyme 17 Reactions Not Available
Enzyme 17 Pfam Domain Function
Enzyme 17 Signals
  • None
Enzyme 17 Transmembrane Regions
  • None
Enzyme 17 Essentiality Not Available
Enzyme 17 GenBank ID Protein 92097584 Link Image
Enzyme 17 UniProtKB/Swiss-Prot ID P41500 Link Image
Enzyme 17 UniProtKB/Swiss-Prot Entry Name ACYP1_BOVIN Link Image
Enzyme 17 PDB ID 2ACY Link Image
Enzyme 17 PDB File Show
Enzyme 17 3D Structure
Enzyme 17 Cellular Location Not Available
Enzyme 17 Gene Sequence >306 bp
ATGAGCATGGCAGAAGGGGATACCCTGATATCAGTGGATTATGAAATTTTTGGAAAGGTG
CAAGGAGTGTTTTTCCGCAAGTACACTCAGGCTGAGGGTAAAAAGCTTGGATTAGTAGGC
TGGGTCCAGAACACTGACCAGGGCACAGTGCAAGGACAATTGCAAGGGCCCGCCTCCAAA
GTACGTCATATGCAGGAATGGCTTGAGACAAAAGGAAGCCCCAAATCACACATCGACAGA
GCAAGCTTCCACAATGAGAAGGTCATCGTAAAGCTGGACTACACAGACTTCCAAATTGTG
AAATAA
Enzyme 17 GenBank Gene ID BC114901 Link Image
Enzyme 17 GeneCard ID ACYP1 Link Image
Enzyme 17 GenAtlas ID Not Available
Enzyme 17 HGNC ID Not Available
Enzyme 17 Chromosome Location Chromosome:1
Enzyme 17 Locus 14q24.3
Enzyme 17 SNPs SNPJam Report Link Image
Enzyme 17 General References
  1. [PubMed Link Image]
Enzyme 17 Metabolite References Not Available
Enzyme 18 [top]
Enzyme 18 ID 152
Enzyme 18 Name Activin receptor type-2B
Enzyme 18 Synonyms
  1. Activin receptor type IIB
  2. ACTR-IIB
Enzyme 18 Gene Name ACVR2B
Enzyme 18 Protein Sequence >Activin receptor type-2B
MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGERDKRLHCY
ASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAG
GPEVTYEPPPTAPTLLTVLAYSLLPVGGLSLIALLAFWMYRHRKPPYGHADIHEDPGPPP
PSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMK
HENLLQFIAAEKRGSSLEAELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSY
LHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVG
TRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQ
HPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSL
IRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI
Enzyme 18 Number of Residues 512
Enzyme 18 Molecular Weight 57568.2
Enzyme 18 Theoretical pI 5.60
Enzyme 18 GO Classification
Function
Process
Component
Enzyme 18 General Function Involved in activin receptor activity
Enzyme 18 Specific Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A
Enzyme 18 Pathways Not Available
Enzyme 18 Reactions Not Available
Enzyme 18 Pfam Domain Function
Enzyme 18 Signals
  • 1-18
Enzyme 18 Transmembrane Regions
  • 138-158
Enzyme 18 Essentiality Not Available
Enzyme 18 GenBank ID Protein 1621097 Link Image
Enzyme 18 UniProtKB/Swiss-Prot ID Q95126 Link Image
Enzyme 18 UniProtKB/Swiss-Prot Entry Name AVR2B_BOVIN Link Image
Enzyme 18 PDB ID 1NYU Link Image
Enzyme 18 PDB File Show
Enzyme 18 3D Structure
Enzyme 18 Cellular Location Not Available
Enzyme 18 Gene Sequence >1539 bp
ATGACGGCGCCCTGGGCGGCCCTCGCCCTCCTTTGGGGATCGCTGTGCGCCGGTTCGGGG
CGCGGGGAGGCCGAGACACGGGAGTGCATCTACTACAACGCCAACTGGGAGCTGGAGCGC
ACCAACCAGAGCGGCCTGGAGCGCTGCGAGGGCGAGCGGGACAAGCGGCTGCACTGCTAC
GCCTCCTGGCGCAACAGCTCGGGCACCATCGAGCTCGTCAAGAAAGGCTGCTGGCTGGAC
GACTTCAACTGCTACGACAGGCAGGAGTGCGTGGCCACCGAGGAGAACCCCCAGGTGTAC
TTCTGCTGCTGCGAAGGCAACTTCTGCAACGAGCGCTTCACCCACCTGCCCGAGGCGGGC
GGCCCAGAAGTCACGTACGAGCCACCCCCGACAGCCCCCACCCTGCTCACTGTGCTGGCC
TACTCGCTGCTGCCCGTCGGGGGCCTCTCCCTCATCGCCCTGCTGGCCTTCTGGATGTAC
CGACATCGCAAGCCCCCCTACGGCCACGCGGACATCCACGAGGACCCTGGACCTCCACCC
CCGTCCCCTCTGGTGGGCCTGAAGCCTCTGCAACTGCTGGAGATCAAGGCTCGGGGGCGC
TTTGGTTGTGTCTGGAAGGCGCAGCTCATGAACGACTTCGTGGCTGTCAAGATCTTCCCA
CTCCAGGACAAGCAGTCGTGGCAGAGTGAGCGGGAGATCTTCAGCACGCCTGGCATGAAG
CACGAGAACCTGCTGCAGTTCATTGCCGCTGAGAAGCGAGGCTCCAGCCTGGAGGCAGAG
CTGTGGCTCATCACGGCCTTCCACGACAAGGGCTCCCTCACGGATTACCTCAAGGGGAAC
ATCATCACATGGAACGAACTGTGTCACGTGGCAGAGACGATGTCTAGAGGCCTCTCATAC
CTACACGAGGATGTGCCCTGGTGCCGGGGCGAGGGCCACAAGCCATCTATTGCCCACAGG
GACTTTAAGAGCAAGAATGTATTGCTGAAGAGTGACCTCACTGCTGTGCTGGCTGACTTT
GGCCTGGCTGTTCGGTTTGAGCCAGGGAAACCTCCGGGGGACACTCACGGGCAGGTGGGC
ACGCGGCGGTACATGGCCCCCGAGGTGCTCGAGGGAGCCATCAACTTCCAGAGAGACGCC
TTTCTGCGCATCGACATGTACGCCATGGGGCTGGTGCTGTGGGAGCTCGTGTCCCGCTGC
AAAGCTGCCGATGGACCTGTGGATGAGTACATGCTGCCTTTTGAGGAGGAGATCGGCCAG
CACCCGTCACTGGAGGAGCTGCAGGAGGTGGTGGTGCACAAGAAGATGCGGCCCGCCATC
AAGGATCACTGGCTGAAACACCCGGGCCTGGCCCAGCTCTGCGTGACCATCGAGGAGTGC
TGGGACCACGATGCAGAGGCTCGCCTGTCTGCGGGCTGTGTGGAGGAGCGAGTGTCCCTG
ATCCGGAGGTCGGTCAACGGCACTACCTCGGACTGTCTTGTCTCCCTGGTGACCTCCGTC
ACCAATGTGGACCTGCCCCCGAAGGAGTCGAGCATCTAA
Enzyme 18 GenBank Gene ID U57707 Link Image
Enzyme 18 GeneCard ID ACVR2B Link Image
Enzyme 18 GenAtlas ID Not Available
Enzyme 18 HGNC ID Not Available
Enzyme 18 Chromosome Location Chromosome:3
Enzyme 18 Locus 3p22
Enzyme 18 SNPs SNPJam Report Link Image
Enzyme 18 General References
  1. [PubMed Link Image]
Enzyme 18 Metabolite References Not Available
Enzyme 19 [top]
Enzyme 19 ID 153
Enzyme 19 Name Calcium-transporting ATPase type 2C member 1
Enzyme 19 Synonyms
  1. ATPase 2C1
  2. Secretory pathway Ca(2+)-transporting ATPase
Enzyme 19 Gene Name ATP2C1
Enzyme 19 Protein Sequence >Calcium-transporting ATPase type 2C member 1
MDNLLPQSRFSYFKKYPIHAIRKYLSMLRNQKEEEQVARFQKIPNAENETMIPVLTSKKA
SELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIML
LLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLMPPECHCVREGK
LEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSVDESSLTGETTPCSKVTAPQPAAT
NGDLASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLG
KQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMV
KKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLRAEVTGVGYNPFGEV
IVDGDVVHGFYNPSVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQDY
IRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYHSKGQTLTLTQQQ
RDLYQQEKAQMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSI
KMITGDSQETAVAIASRLGLYSKTSQSVSGEEIDAMDVQQLSQIVPKVAVFYRASPRHKM
KIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIM
SAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPA
QSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVITPR
DTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQK
VFQTESLSILDLLFLLGLTSSVCIVAEIIKKVERSREKIQKPVSSTSSSFLEV
Enzyme 19 Number of Residues 953
Enzyme 19 Molecular Weight 104779.3
Enzyme 19 Theoretical pI 7.01
Enzyme 19 GO Classification
Function
Process
Component
Enzyme 19 General Function Inorganic ion transport and metabolism
Enzyme 19 Specific Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium
Enzyme 19 Pathways Not Available
Enzyme 19 Reactions Not Available
Enzyme 19 Pfam Domain Function
Enzyme 19 Signals
  • None
Enzyme 19 Transmembrane Regions
  • 105-125 139-157 297-316 329-346 734-753 764-784 805-824 843-862 876-894 910-930
Enzyme 19 Essentiality Not Available
Enzyme 19 GenBank ID Protein 7595749 Link Image
Enzyme 19 UniProtKB/Swiss-Prot ID P57709 Link Image
Enzyme 19 UniProtKB/Swiss-Prot Entry Name AT2C1_BOVIN Link Image
Enzyme 19 PDB ID Not Available
Enzyme 19 Cellular Location Not Available
Enzyme 19 Gene Sequence >2862 bp
ATGGATAATCTGTTGCCTCAGTCAAGATTCTCTTATTTCAAAAAATATCCTATCCATGCA
ATTAGAAAATATTTATCGATGCTGAGAAACCAAAAAGAAGAAGAACAGGTTGCACGTTTT
CAAAAAATTCCTAATGCTGAAAATGAGACAATGATTCCGGTATTGACATCAAAAAAAGCA
AGTGAATTACCAGTCAGTGAAGTTGCAAGCATTCTCCAAGCTGATCTTCAGAATGGTCTA
AACAAATGTGAAGTAAGTCATAGGAGAGCCTTCCATGGCTGGAATGAGTTTGATATCAGT
GAAGATGAGCCACTATGGAAGAAGTATATTTCTCAGTTTAAAAATCCCCTTATTATGCTG
CTTCTGGCTTCTGCAGTCATCAGTGTTTTAATGCATCAGTTTGATGATGCTGTCAGTATC
ACTGTGGCAATACTTATTGTTGTTACGGTCGCCTTCGTTCAGGAATATCGTTCAGAAAAA
TCTCTTGAAGAACTAAGTAAACTTATGCCACCAGAATGCCATTGTGTGCGTGAAGGAAAA
TTGGAGCATACACTTGCACGAGACTTAGTTCCAGGTGATACAGTTTGCCTTTCAGTTGGG
GACAGGGTTCCTGCTGACTTGCGCTTGTTTGAGGCTGTGGATCTTTCTGTTGATGAGTCC
AGCTTGACAGGAGAGACAACACCTTGTTCTAAGGTGACAGCTCCTCAGCCGGCTGCTACT
AATGGAGATCTTGCATCAAGAAGTAACATTGCCTTCATGGGAACACTGGTCAGATGTGGC
AAAGCAAAGGGTATTGTCATTGGAACAGGAGAAAATTCTGAATTCGGAGAAGTTTTTAAA
ATGATGCAAGCAGAAGAAGCACCAAAAACCCCTCTGCAGAAGAGCATGGACCTCTTAGGA
AAACAACTTTCCTTTTACTCCTTTGGTATAATAGGTATCATCATGTTGGTTGGCTGGTTG
CTAGGAAAAGACATATTGGAAATGTTTACTATTAGTGTAAGTTTGGCTGTAGCAGCAATT
CCTGAAGGTCTTCCCATTGTGGTCACAGTGACTCTAGCCCTTGGTGTTATGAGAATGGTG
AAGAAGAGGGCGATTGTGAAAAAACTACCTATTGTTGAAACTCTGGGTTGCTGTAATGTG
ATTTGTTCAGATAAGACTGGAACCCTGACCAAGAATGAAATGACTGTTACCCACATATTT
ACTTCGGATGGCCTGCGTGCTGAGGTTACTGGAGTTGGCTACAATCCATTTGGGGAAGTG
ATTGTTGATGGTGATGTTGTTCATGGATTCTATAACCCATCTGTTAGTAGAATTGTTGAG
GCTGGCTGTGTGTGCAATGATGCTGTAATTAGAAATAACACTCTAATGGGGAAACCAACG
GAAGGAGCCTTAATTGCTCTTGCAATGAAGATGGGTCTTGATGGACTTCAACAGGATTAT
ATCAGAAAAGCTGAATACCCTTTTAGCTCTGAGCAGAAGTGGATGGCTGTTAAGTGTGTG
CACCGAACACAGCAGGACAGACCAGAGATTTGTTTTATGAAGGGTGCTTATGAACAGGTG
ATTAAGTATTGTACTACATATCACAGCAAAGGACAGACCTTGACACTCACCCAGCAGCAG
AGAGATCTGTACCAGCAAGAGAAGGCCCAGATGGGCTCTGCAGGGCTCAGAGTTCTTGCT
TTGGCTTCTGGTCCTGAATTGGGACAACTGACGTTCCTTGGCCTGGTGGGAATCATTGAT
CCTCCTAGAACTGGTGTGAAAGAAGCCGTTACAACACTCATTGCCTCAGGAGTATCAATA
AAAATGATTACTGGAGACTCACAGGAGACTGCAGTTGCCATCGCTAGTCGTCTGGGATTA
TATTCCAAAACCTCCCAGTCAGTCTCAGGAGAAGAAATAGATGCAATGGATGTCCAGCAG
CTTTCACAAATAGTGCCAAAGGTTGCAGTATTTTACAGAGCTAGCCCAAGGCATAAGATG
AAAATTATCAAGTCTCTGCAGAAGAATGGGTCAGTTGTGGCCATGACAGGAGATGGAGTA
AATGATGCAGTTGCTCTGAAGGCTGCAGACATTGGAGTTGCGATGGGTCAGACTGGCACA
GATGTTTGCAAAGAGGCAGCTGACATGATCCTGGTGGATGATGATTTCCAAACCATCATG
TCTGCAATTGAAGAGGGTAAAGGGATTTATAATAACATTAAAAATTTTGTTAGATTCCAG
CTGAGCACGAGTATAGCAGCATTAACTTTAATCTCACTGGCTACATTAATGAACTTTCCC
AATCCTCTCAATGCCATGCAGATTTTGTGGATCAATATTATTATGGATGGACCTCCAGCT
CAGAGCCTTGGAGTAGAACCAGTGGATAAAGATGTCATTCGTAAACCTCCACGCAACTGG
AAAGACAGCATTTTGACCAAAAACCTGATACTTAAAATACTTGTTTCCTCAATAATCATT
GTTTGTGGGACTTTGTTTGTCTTCTGGCGGGAGCTGCGAGACAATGTGATAACACCTCGG
GACACAACAATGACTTTCACGTGCTTTGTGTTTTTTGACATGTTCAATGCACTGAGTTCC
AGATCTCAGACCAAATCTGTGTTTGAGATTGGACTCTGCAGTAATAAAATGTTTTGCTAT
GCAGTTCTTGGATCCATCATGGGACAGTTATTAGTTATTTACTTTCCTCCACTTCAGAAA
GTTTTTCAGACTGAGAGCCTAAGTATACTGGATTTACTGTTTCTTCTGGGTCTCACCTCG
TCAGTGTGCATAGTGGCAGAAATTATCAAGAAGGTTGAAAGGAGCAGAGAGAAGATCCAG
AAGCCTGTTAGCTCGACATCATCGTCTTTTCTTGAAGTATGA
Enzyme 19 GenBank Gene ID AF230532 Link Image
Enzyme 19 GeneCard ID ATP2C1 Link Image
Enzyme 19 GenAtlas ID Not Available
Enzyme 19 HGNC ID Not Available
Enzyme 19 Chromosome Location Chromosome:3
Enzyme 19 Locus 3q22.1
Enzyme 19 SNPs SNPJam Report Link Image
Enzyme 19 General References Not Available
Enzyme 19 Metabolite References Not Available
Enzyme 20 [top]
Enzyme 20 ID 154
Enzyme 20 Name Glyceraldehyde-3-phosphate dehydrogenase
Enzyme 20 Synonyms
  1. GAPDH
Enzyme 20 Gene Name GAPDH
Enzyme 20 Protein Sequence >Glyceraldehyde-3-phosphate dehydrogenase
MVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLHYMVYMFQYDSTHGKFNGTVKA
ENGKLVINGKAITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIIS
APSADAPMFVMGVNHEKYNNTLKIVSNASCTTNCLAPLAKVIHDHFGIVEGLMTTVHAIT
ATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSV
VDLTCRLEKPAKYDEIKKVVKQASEGPLKGILGYTEDQVVSCDFNSDTHSSTFDAGAGIA
LNDHFVKLISWYDNEFGYSNRVVDLMVHMASKE
Enzyme 20 Number of Residues 333
Enzyme 20 Molecular Weight 35867.9
Enzyme 20 Theoretical pI 8.58
Enzyme 20 GO Classification
Function
Process
Component
Enzyme 20 General Function Carbohydrate transport and metabolism
Enzyme 20 Specific Function D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH
Enzyme 20 Pathways
  • Carbohydrate degradation
  • glycolysis
  • pyruvate from D- glyceraldehyde 3-phosphate:step 1/5
Enzyme 20 Reactions Not Available
Enzyme 20 Pfam Domain Function
Enzyme 20 Signals
  • None
Enzyme 20 Transmembrane Regions
  • None
Enzyme 20 Essentiality Not Available
Enzyme 20 GenBank ID Protein 73587299 Link Image
Enzyme 20 UniProtKB/Swiss-Prot ID P10096 Link Image
Enzyme 20 UniProtKB/Swiss-Prot Entry Name G3P_BOVIN Link Image
Enzyme 20 PDB ID 1J0X Link Image
Enzyme 20 PDB File Show
Enzyme 20 3D Structure
Enzyme 20 Cellular Location Not Available
Enzyme 20 Gene Sequence >1002 bp
ATGGTGAAGGTCGGAGTGAACGGATTCGGCCGCATCGGGCGCCTGGTCACCAGGGCTGCT
TTTAATTCTGGCAAAGTGGACATCGTCGCCATCAATGACCCCTTCATTGACCTTCACTAC
ATGGTCTACATGTTCCAGTATGATTCCACCCACGGCAAGTTCAACGGCACAGTCAAGGCA
GAGAACGGGAAGCTCGTCATCAATGGAAAGGCCATCACCATCTTCCAGGAGCGAGATCCT
GCCAACATCAAGTGGGGTGATGCTGGTGCTGAGTATGTGGTGGAGTCCACTGGGGTCTTC
ACTACCATGGAGAAGGCTGGGGCTCACTTGAAGGGTGGCGCCAAGAGGGTCATCATCTCT
GCACCTTCTGCCGATGCCCCCATGTTTGTGATGGGCGTGAACCACGAGAAGTATAACAAC
ACCCTCAAGATTGTCAGCAATGCCTCCTGCACCACCAACTGCTTGGCCCCCCTGGCCAAG
GTCATCCATGACCACTTTGGCATCGTGGAGGGACTTATGACCACTGTCCACGCCATCACT
GCCACCCAGAAGACTGTGGATGGCCCCTCCGGGAAGCTGTGGCGTGACGGCCGAGGGGCT
GCCCAGAATATCATCCCTGCTTCTACTGGCGCTGCCAAGGCCGTGGGCAAGGTCATCCCT
GAGCTCAACGGGAAGCTCACTGGCATGGCCTTCCGCGTCCCCACTCCCAACGTGTCTGTT
GTGGATCTGACCTGCCGCCTGGAGAAACCTGCCAAGTATGATGAGATCAAGAAGGTGGTG
AAGCAGGCGTCAGAGGGCCCTCTCAAGGGCATTCTAGGCTACACTGAGGACCAGGTTGTC
TCCTGCGACTTCAACAGCGACACTCACTCTTCTACCTTCGATGCTGGGGCTGGCATTGCC
CTCAACGACCACTTTGTCAAGCTCATTTCCTGGTACGACAATGAATTTGGCTACAGCAAC
AGGGTGGTGGACCTCATGGTCCACATGGCCTCCAAGGAGTAA
Enzyme 20 GenBank Gene ID BC102589 Link Image
Enzyme 20 GeneCard ID GAPDH Link Image
Enzyme 20 GenAtlas ID Not Available
Enzyme 20 HGNC ID Not Available
Enzyme 20 Chromosome Location Chromosome:1
Enzyme 20 Locus 12p13
Enzyme 20 SNPs SNPJam Report Link Image
Enzyme 20 General References
  1. [PubMed Link Image]
Enzyme 20 Metabolite References Not Available
Enzyme 21 [top]
Enzyme 21 ID 155
Enzyme 21 Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Enzyme 21 Synonyms
  1. 6PF-2-K/Fru-2,6-P2ASE brain/placenta-type isozyme
  2. 6-phosphofructo-2-kinase
  3. Fructose-2,6-bisphosphatase
Enzyme 21 Gene Name PFKFB3
Enzyme 21 Protein Sequence >6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
MPLELTQSRVQKIWIPVDHRPSLPRTCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
WIGVPTKVFNLGEYRRDGVKQYSSYNFFRPDNEEAMKVRKQCALAALRDVKSYLTKEGGQ
IAVFDATNTTRERRHMILHFPKENDFKVFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
RENAMDDFMKRINCYEASYQPLDPDNDDRDLSLIKVIDVGQRFLVNRVQDHIQRRIVYYL
MNIHWQPRTIYLCRHGESKHNLQGKIGGDSGLSSRGRKFANALSKFVEEQNLKDLKVWTS
QLKSTIQTAEALQLPYEQWKALNEIDAGVCEEMTYEEIKDTYPEEYALAEADKYYYRYPT
GESYQDLVQRLEPVIMELERQENVLVICHQAVCVCLLAYFLDKSAEEMPYLKCPLHAVLK
LTPIAYGCRVESIYLNVESVSTHRERSEDAKKGPNPLMRSNSH
Enzyme 21 Number of Residues 463
Enzyme 21 Molecular Weight 53583.8
Enzyme 21 Theoretical pI 7.66
Enzyme 21 GO Classification
Function
Process
Component
Enzyme 21 General Function Carbohydrate transport and metabolism
Enzyme 21 Specific Function Synthesis and degradation of fructose 2,6-bisphosphate
Enzyme 21 Pathways Not Available
Enzyme 21 Reactions Not Available
Enzyme 21 Pfam Domain Function
Enzyme 21 Signals
  • None
Enzyme 21 Transmembrane Regions
  • None
Enzyme 21 Essentiality Not Available
Enzyme 21 GenBank ID Protein 7544879 Link Image
Enzyme 21 UniProtKB/Swiss-Prot ID Q28901 Link Image
Enzyme 21 UniProtKB/Swiss-Prot Entry Name F263_BOVIN Link Image
Enzyme 21 PDB ID Not Available
Enzyme 21 Cellular Location Not Available
Enzyme 21 Gene Sequence Not Available
Enzyme 21 GenBank Gene ID S77845 Link Image
Enzyme 21 GeneCard ID PFKFB3 Link Image
Enzyme 21 GenAtlas ID Not Available
Enzyme 21 HGNC ID Not Available
Enzyme 21 Chromosome Location Chromosome:1
Enzyme 21 Locus 10p14-p15
Enzyme 21 SNPs SNPJam Report Link Image
Enzyme 21 General References
  1. [PubMed Link Image]
Enzyme 21 Metabolite References Not Available
Enzyme 22 [top]
Enzyme 22 ID 156
Enzyme 22 Name Ectonucleoside triphosphate diphosphohydrolase 8
Enzyme 22 Synonyms
  1. E-NTPDase 8
  2. NTPDase 8
  3. NTPDase8
Enzyme 22 Gene Name ENTPD8
Enzyme 22 Protein Sequence >Ectonucleoside triphosphate diphosphohydrolase 8
MGLTWKQRVFTALLGAAAVSGLTALLLVLVGTMNVLLPPDTKFGIVFDAGSSHTSLFVYQ
WPANKENDTGIVSQALACQAEGPGISSYASNPARVGESLQGCLEEALALIPKAKHHETPM
FLGATAGMRLLSRKNRSQAEDVFAAVSRALGQSPVDFRGAELLTGQDEGAFGWITINYIL
GLLVKYSFSGEWIRPLEETLVGALDMGGASTQITFVPGGPILDKTAQATFRLYGADHTVY
THSYLCFGRDQALSRVLAELVQASTGLLIRHPCYHSGYRGTLALASLYESPCAPAAPPDL
SQNLTVEGTGNPGACVEALRKLFNFSSCDGREDCAFAGVYQPPVQGQFYAFSNFYYTFNF
LNLTSKPSLSGANATIWEFCLRPWKLVEASAPPGQDRWLRDYCASGLYILTLLVEGYGFS
EETWGGIEFRQQAGGADIGWTLGYMLNLTNLIPAEAPAQGWAQSFGVWAAGVVFVVLTLA
ATLGAVAVQVFWLQD
Enzyme 22 Number of Residues 495
Enzyme 22 Molecular Weight 53239.2
Enzyme 22 Theoretical pI 4.97
Enzyme 22 GO Classification
Function
Process
Component
Enzyme 22 General Function Not Available
Enzyme 22 Specific Function Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolyzis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP
Enzyme 22 Pathways Not Available
Enzyme 22 Reactions Not Available
Enzyme 22 Pfam Domain Function
Enzyme 22 Signals
  • None
Enzyme 22 Transmembrane Regions
  • 9-29 467-487
Enzyme 22 Essentiality Not Available
Enzyme 22 GenBank ID Protein 117306525 Link Image
Enzyme 22 UniProtKB/Swiss-Prot ID A0JND9 Link Image
Enzyme 22 UniProtKB/Swiss-Prot Entry Name ENTP8_BOVIN Link Image
Enzyme 22 PDB ID Not Available
Enzyme 22 Cellular Location Not Available
Enzyme 22 Gene Sequence >1488 bp
ATGGGGCTGACCTGGAAGCAGCGGGTCTTCACGGCTCTGCTGGGCGCAGCAGCGGTCTCA
GGCCTCACCGCGCTGCTTCTCGTCCTGGTGGGGACCATGAACGTCCTCCTGCCTCCAGAC
ACCAAGTTTGGGATCGTGTTCGACGCTGGGTCCTCCCACACATCCCTCTTTGTGTATCAG
TGGCCGGCCAACAAGGAGAACGACACCGGCATAGTCAGCCAGGCCCTGGCCTGCCAGGCG
GAAGGGCCTGGAATCTCGTCTTACGCCTCCAACCCTGCGCGGGTTGGCGAGAGCCTGCAG
GGCTGCCTGGAGGAGGCGCTAGCACTGATCCCAAAGGCCAAGCATCATGAGACACCCATG
TTCCTGGGGGCCACTGCAGGCATGCGGCTGCTCAGCCGCAAGAATCGCTCCCAGGCGGAG
GACGTGTTCGCCGCGGTCAGCCGGGCCCTGGGCCAGTCACCGGTGGACTTCCGGGGCGCA
GAGCTCCTGACGGGGCAGGACGAAGGCGCCTTTGGTTGGATCACCATCAACTACATCCTT
GGCCTGCTGGTGAAGTACTCCTTCTCTGGAGAGTGGATCCGGCCCCTGGAGGAGACGCTG
GTGGGCGCCCTGGACATGGGTGGGGCCTCCACCCAGATTACCTTTGTACCTGGAGGCCCC
ATCCTGGACAAGACCGCCCAGGCCACCTTCCGCCTCTACGGTGCCGACCACACCGTCTAC
ACCCACAGCTACCTCTGCTTCGGGCGCGACCAGGCGCTGAGCAGGGTGCTGGCCGAGCTG
GTGCAGGCCAGCACGGGCCTCCTGATCCGCCACCCCTGCTACCACAGCGGCTACCGGGGC
ACGCTGGCCCTGGCGTCCCTGTATGAGTCGCCCTGCGCCCCGGCAGCGCCCCCCGACCTC
AGCCAGAACCTCACCGTGGAGGGCACGGGGAACCCCGGGGCCTGCGTCGAGGCCCTCCGG
AAGCTCTTCAATTTCTCCAGCTGTGACGGCCGAGAAGACTGTGCCTTCGCCGGGGTCTAC
CAGCCCCCCGTGCAGGGCCAGTTCTACGCTTTCTCCAACTTCTACTACACCTTCAACTTC
CTGAACCTCACCTCCAAGCCGTCACTGAGTGGGGCCAACGCCACCATCTGGGAGTTCTGC
CTGCGGCCCTGGAAGCTGGTGGAGGCGAGCGCGCCCCCGGGCCAGGACCGCTGGCTGCGG
GACTACTGTGCCTCGGGCCTATACATCCTCACGCTCCTGGTCGAGGGCTACGGGTTCAGT
GAGGAGACCTGGGGAGGCATCGAGTTCCGCCAGCAGGCCGGCGGCGCTGACATCGGCTGG
ACGCTGGGCTACATGCTGAACCTGACCAACCTGATCCCGGCCGAGGCGCCCGCCCAGGGT
TGGGCACAGAGCTTCGGCGTCTGGGCGGCCGGGGTCGTCTTCGTGGTGCTGACGCTCGCG
GCCACCCTGGGTGCCGTGGCAGTGCAGGTCTTCTGGCTCCAGGACTAG
Enzyme 22 GenBank Gene ID BC126637 Link Image
Enzyme 22 GeneCard ID ENTPD8 Link Image
Enzyme 22 GenAtlas ID Not Available
Enzyme 22 HGNC ID Not Available
Enzyme 22 Chromosome Location Chromosome:9
Enzyme 22 Locus 9q34.3
Enzyme 22 SNPs SNPJam Report Link Image
Enzyme 22 General References Not Available
Enzyme 22 Metabolite References Not Available
Enzyme 23 [top]
Enzyme 23 ID 157
Enzyme 23 Name Probable phospholipid-transporting ATPase IIB
Enzyme 23 Synonyms
  1. ATPase class II type 9B
Enzyme 23 Gene Name ATP9B
Enzyme 23 Protein Sequence >Probable phospholipid-transporting ATPase IIB
MADQIPLYPVRSAAAVAAANRKRAAYFSSAGPGPGADRPSRYQLEDESAHLDEMPLMMSE
EGFENDESDYHTLPRARITRRKRGLEWFVCGGWKFLCTSCCDWLINICQRKRELKARTVW
LGCPEKCEEKHPRNSIKNQKYNIFTFIPGVLYEQFKFFLNLYFLIVSCSQFVPALKIGYL
YTYWAPLGFVLAVTIMREAVDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLII
VEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQRLPALGDLFSINAY
VYAQKPQLDIHSFEGTFTREDSDPPVHESLSIENTLWASTVVASGTVIGVVIYTGKETRS
VMNTSNPKNKVGLLDLELNQLTKALFLALVALSVVMVTLQGFAGPWYRSLFRFLLLFSYI
IPISLRVNLDMGKAAYGWMIMRDEHIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMV
FKRLHLGTVSYGTDTMDEIQNHLVNAYTQTQCQAGGSSAASTPPRKAPSSAPKVRRSVSS
RVHEAVKAVALCHNVTPVYEARGAAGETEVAEADQDFSDDNRTYQASSPDEVALVQWTES
VGLTLVSRDLTSMQLRTPGGQILTYCILQTFPFTSESKRMGVIVRDESTAEITFYMKGAD
VAMASIVQYNDWLEEECGNMAREGLRTLVVAKRALTEEQYQDFESRYNQAKLSLHDRTLK
VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS
HLVSRTQDTHVFRPVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQ
CPAVVCCRCSPTQKAHIVKLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGRQAS
LAADFSITRFKHVGRLLMVHGRSSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPL
YQGFLMVGYATVYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLVWVLIS
IYQGGILMFGALVLFESEFVHVVAISFTALVLTELLMVALTVRTWHWLMVVAQLLSLGCY
VASLAFLNEYFDVAFITTVTFVWKVSAITVVSCLPLYVLKYLKRKLSPPSYSKLSS
Enzyme 23 Number of Residues 1136
Enzyme 23 Molecular Weight 127456.0
Enzyme 23 Theoretical pI 7.73
Enzyme 23 GO Classification
Function
Process
Component
Enzyme 23 General Function Inorganic ion transport and metabolism
Enzyme 23 Specific Function ATP + H(2)O + phospholipid(In) = ADP + phosphate + phospholipid(Out)
Enzyme 23 Pathways Not Available
Enzyme 23 Reactions Not Available
Enzyme 23 Pfam Domain Function
Enzyme 23 Signals
  • None
Enzyme 23 Transmembrane Regions
  • 146-166 175-195 384-404 409-429 940-960 963-983 1013-1033 1042-1062 1067-1087 1099-1119
Enzyme 23 Essentiality Not Available
Enzyme 23 GenBank ID Protein 119224098 Link Image
Enzyme 23 UniProtKB/Swiss-Prot ID A1A4J6 Link Image
Enzyme 23 UniProtKB/Swiss-Prot Entry Name ATP9B_BOVIN Link Image
Enzyme 23 PDB ID Not Available
Enzyme 23 Cellular Location Not Available
Enzyme 23 Gene Sequence >3411 bp
ATGGCGGACCAGATCCCTCTGTACCCGGTGCGCAGCGCGGCGGCCGTGGCCGCGGCCAAC
CGTAAACGCGCGGCCTACTTCAGCTCAGCGGGGCCCGGGCCGGGGGCCGACAGGCCCAGC
AGGTACCAGCTGGAGGATGAGTCTGCCCACTTGGATGAAATGCCACTGATGATGTCTGAA
GAGGGCTTTGAGAACGACGAAAGTGATTACCACACTTTACCACGAGCTAGGATCACCCGA
AGAAAGAGAGGCCTGGAGTGGTTTGTCTGTGGGGGATGGAAGTTCCTCTGTACCAGTTGC
TGTGACTGGCTGATAAATATTTGTCAAAGAAAGAGAGAATTGAAAGCTCGTACGGTGTGG
CTTGGATGTCCGGAAAAGTGTGAAGAAAAACATCCCAGAAATTCTATAAAAAATCAGAAA
TATAATATATTTACCTTTATACCTGGGGTTTTATATGAACAATTCAAATTTTTCCTGAAT
CTCTATTTCCTGATAGTATCCTGCTCACAGTTTGTACCAGCACTGAAAATAGGGTATCTC
TACACCTACTGGGCTCCTCTGGGGTTTGTCTTGGCTGTTACTATCATGAGAGAAGCAGTT
GATGAATTTCGGCGTTTCCAGCGAGACAAGGAAGTGAACTCACAACTGTACAGCAAGCTT
ACAGTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTGGAGACCTCATCATA
GTGGAAAAGAATCAAAGAATTCCATCGGACATGGTATTTCTTAGGACGTCAGAAAAAGCA
GGTTCGTGTTTTATTCGAACTGATCAACTCGATGGTGAAACTGACTGGAAGCTGAAAGTG
GCGGTGAGCTGCACACAGAGGCTGCCCGCTCTGGGGGACCTTTTTTCTATCAATGCTTAT
GTTTATGCTCAGAAGCCACAACTGGATATTCATAGTTTTGAAGGCACATTTACGAGGGAA
GACAGTGATCCACCTGTTCATGAAAGTCTCAGCATAGAAAATACATTGTGGGCAAGCACT
GTGGTTGCATCAGGTACTGTAATAGGTGTGGTCATCTATACTGGAAAAGAGACTAGAAGT
GTCATGAACACATCAAATCCAAAAAACAAGGTTGGTCTGTTGGATCTTGAACTCAACCAG
CTGACCAAAGCACTATTTCTGGCCTTGGTTGCCCTCTCGGTTGTCATGGTGACCTTGCAG
GGATTTGCAGGCCCCTGGTACCGCAGTCTCTTCCGCTTTCTCCTCCTCTTCTCCTACATC
ATTCCCATAAGTTTGCGTGTGAACCTGGACATGGGCAAGGCTGCCTACGGGTGGATGATC
ATGAGAGACGAGCACATTCCCGGCACCGTGGTCCGGACCAGCACCATCCCGGAGGAGCTG
GGGCGCCTGGTGTACCTGCTGACCGACAAGACAGGAACCCTCACCCAAAACGAGATGGTG
TTTAAGCGGCTGCACCTGGGCACCGTGTCTTACGGGACGGACACGATGGATGAGATCCAG
AACCACCTCGTGAACGCCTACACACAGACGCAGTGTCAGGCTGGCGGAAGCAGCGCTGCT
TCAACTCCTCCAAGGAAAGCCCCGTCGTCAGCGCCCAAGGTGAGGAGGAGCGTGAGCAGC
CGGGTCCATGAGGCCGTGAAGGCTGTCGCCCTGTGTCACAATGTGACGCCCGTGTACGAG
GCCCGCGGTGCAGCTGGCGAGACCGAGGTCGCCGAGGCGGACCAGGATTTCAGTGATGAC
AACCGCACCTACCAGGCCTCCAGCCCTGACGAGGTGGCCCTGGTGCAGTGGACAGAGAGC
GTCGGCCTCACGCTGGTCAGCAGAGACCTCACGTCCATGCAGCTGCGGACCCCCGGCGGC
CAGATCCTCACCTACTGCATCCTTCAGACCTTCCCCTTCACGTCGGAGAGCAAGCGCATG
GGGGTCATCGTCAGGGACGAGTCCACAGCAGAGATCACGTTCTACATGAAGGGCGCCGAC
GTGGCCATGGCCTCCATCGTGCAATACAACGATTGGCTGGAGGAGGAGTGTGGGAACATG
GCCCGCGAAGGCCTGCGCACGCTCGTGGTGGCCAAGAGGGCACTCACGGAGGAGCAGTAC
CAGGACTTCGAGAGCCGCTACAACCAGGCCAAGCTGAGCCTCCACGACCGGACGCTCAAG
GTGGCCGCTGTGGTGGAGAGCCTGGAGCGGGAGATGGAGCTGCTGTGCCTGACGGGCGTG
GAGGACCAGCTGCAGGCAGACGTGAGGCCCACCCTGGAGATGCTGCGCAACGCTGGCATC
AAGATCTGGATGCTGACAGGCGACAAGCTGGAGACCGCCACGTGCATCGCCAAGAGTTCC
CACCTGGTGTCACGAACGCAGGACACGCATGTTTTCAGGCCGGTGACCAGCCGCGGAGAA
GCCCACCTGGAGCTGAATGCCTTTCGAAGGAAACATGACTGCGCACTGGTCATTTCCGGG
GACTCCCTGGAGGTCTGCTTGAAGTACTACGAGCACGAGTTTGTGGAGCTGGCCTGCCAG
TGCCCGGCCGTGGTCTGCTGCCGCTGCTCGCCCACCCAGAAGGCCCACATCGTCAAGCTG
CTGCAGCAACACACAGGCCGCCGCACCTGCGCCATCGGTGACGGAGGGAACGACGTGAGC
ATGATCCAGGCGGCGGACTGCGGGATCGGCATCGAGGGGAAGGAGGGGCGGCAGGCCTCA
CTGGCAGCTGACTTCTCCATCACGCGGTTCAAGCACGTTGGCCGTCTGCTCATGGTGCAC
GGGCGCAGCAGCTACAAGCGCTCGGCGGCACTCGGCCAGTTCGTCATGCACCGGGGCCTC
ATCATCTCCACGATGCAGGCTGTGTTCTCCTCCGTCTTCTACTTTGCATCGGTCCCTCTG
TACCAGGGTTTCCTCATGGTGGGGTACGCAACCGTCTACACCATGTTCCCCGTGTTCTCG
CTGGTGCTGGACCAGGATGTGAAGCCGGAGATGGCCATGCTGTACCCAGAGCTGTACAAG
GACCTCACCAAGGGGCGATCCTTATCCTTCAAGACCTTCCTCGTCTGGGTTCTGATCAGC
ATTTACCAAGGTGGCATCCTCATGTTCGGGGCGCTGGTGCTGTTTGAGTCTGAGTTCGTG
CACGTGGTGGCCATCTCCTTCACGGCGCTGGTGCTCACGGAGCTGCTGATGGTGGCGCTG
ACCGTCAGGACCTGGCACTGGCTCATGGTCGTGGCCCAGCTGCTCAGCCTCGGCTGCTAC
GTGGCCTCGCTGGCTTTCCTCAATGAATATTTTGACGTTGCCTTTATCACGACTGTGACC
TTCGTGTGGAAAGTGTCAGCCATCACAGTGGTCAGCTGCCTCCCTCTCTATGTCCTGAAG
TACTTGAAGCGGAAGCTGTCCCCGCCCAGCTACTCCAAGCTCTCCTCCTAG
Enzyme 23 GenBank Gene ID BC126606 Link Image
Enzyme 23 GeneCard ID ATP9B Link Image
Enzyme 23 GenAtlas ID Not Available
Enzyme 23 HGNC ID Not Available
Enzyme 23 Chromosome Location Chromosome:1
Enzyme 23 Locus 18q23
Enzyme 23 SNPs SNPJam Report Link Image
Enzyme 23 General References Not Available
Enzyme 23 Metabolite References Not Available
Enzyme 24 [top]
Enzyme 24 ID 158
Enzyme 24 Name Sodium/potassium-transporting ATPase subunit alpha-2
Enzyme 24 Synonyms
  1. Sodium pump subunit alpha-2
  2. Na(+)/K(+) ATPase alpha-2 subunit
Enzyme 24 Gene Name ATP1A2
Enzyme 24 Protein Sequence >Sodium/potassium-transporting ATPase subunit alpha-2
MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG
LTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAFGIQAAME
DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVVREGEKMQINA
EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI
CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL
GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS
RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPF
NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSSILVQGKEIPLDKEMQDAFQNAYL
ELGGLGERVLGFCQLNLPSAKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV
GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPREAKAC
VVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP
ALKKADIGIAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN
IPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPQTDK
LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRSMNDLEDSYG
QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETA
LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY
Enzyme 24 Number of Residues 1020
Enzyme 24 Molecular Weight 112178.3
Enzyme 24 Theoretical pI 5.33
Enzyme 24 GO Classification
Function
Process
Component
Enzyme 24 General Function Inorganic ion transport and metabolism
Enzyme 24 Specific Function This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium, providing the energy for active transport of various nutrients
Enzyme 24 Pathways Not Available
Enzyme 24 Reactions Not Available
Enzyme 24 Pfam Domain Function
Enzyme 24 Signals
  • None
Enzyme 24 Transmembrane Regions
  • 86-106 130-150 287-306 319-336 770-789 800-820 841-863 916-935 949-967 983-1003
Enzyme 24 Essentiality Not Available
Enzyme 24 GenBank ID Protein 124829106 Link Image
Enzyme 24 UniProtKB/Swiss-Prot ID A2VDL6 Link Image
Enzyme 24 UniProtKB/Swiss-Prot Entry Name AT1A2_BOVIN Link Image
Enzyme 24 PDB ID 1Q3I Link Image
Enzyme 24 PDB File Show
Enzyme 24 3D Structure
Enzyme 24 Cellular Location Not Available
Enzyme 24 Gene Sequence >3063 bp
ATGGGCCGTGGGGCTGGCCGCGAGTACTCGCCTGCAGCCACCACTGCGGAAAATGGGGGC
GGCAAGAAGAAACAGAAAGAGAAGGAGCTGGATGAGCTGAAGAAGGAAGTGGCCATGGAT
GACCACAAGCTGTCCTTGGATGAGCTGGGCCGCAAGTACCAAGTGGATCTGTCCAAGGGC
CTCACCAACCAGCGGGCCCAGGACATTCTGGCTCGGGATGGACCCAATGCCCTCACCCCA
CCCCCAACCACCCCTGAGTGGGTCAAGTTCTGTCGTCAGCTTTTCGGGGGCTTCTCCATC
CTACTGTGGATTGGGGCCATCCTCTGCTTCCTGGCCTTTGGCATCCAGGCTGCCATGGAG
GATGAACCGTCCAACGACAATCTTTATCTGGGCGTGGTGCTGGCAGCTGTGGTCATCGTC
ACTGGCTGCTTCTCCTACTACCAGGAGGCCAAGAGCTCCAAGATCATGGATTCCTTCAAG
AACATGGTGCCTCAGCAAGCCCTTGTGGTGCGAGAAGGAGAGAAGATGCAGATCAACGCG
GAGGAGGTGGTGGTGGGCGACCTGGTGGAGGTGAAGGGTGGGGACCGCGTGCCCGCTGAC
CTCCGGATCATCTCTTCTCACGGCTGCAAGGTGGACAACTCCTCCCTGACAGGCGAGTCA
GAACCCCAGACCCGCTCCCCTGAGTTCACCCACGAGAATCCCCTGGAGACCCGCAATATC
TGTTTCTTCTCTACCAACTGTGTGGAAGGCACTGCCAGGGGCATCGTGATTGCCACAGGT
GACCGGACGGTGATGGGCCGTATAGCCACTCTGGCCTCAGGCCTGGAGGTCGGGCGGACG
CCCATAGCCATGGAGATTGAGCACTTCATTCAGCTGATCACAGGGGTGGCCGTCTTCCTG
GGGGTCTCCTTCTTCGTGCTGTCCCTCATCCTGGGCTACAGCTGGCTGGAGGCGGTCATC
TTCCTTATCGGCATCATTGTGGCCAACGTGCCTGAGGGTCTGCTGGCCACTGTCACCGTG
TGTCTGACCCTGACAGCCAAGCGCATGGCTCGGAAGAACTGCCTGGTGAAGAACCTGGAG
GCGGTGGAGACTCTGGGCTCCACCTCCACCATCTGCTCCGACAAGACCGGAACCCTCACC
CAGAACCGCATGACCGTCGCCCACATGTGGTTCGACAATCAGATCCATGAGGCCGACACC
ACGGAAGATCAGTCTGGGGCCACTTTTGACAAACGATCCCCGACATGGACTGCCCTATCC
CGGATTGCTGGTCTCTGCAACCGTGCTGTGTTCAAGGCAGGGCAGGAAAACATCTCTGTG
TCTAAGCGGGACACAGCAGGTGATGCCTCCGAGTCAGCTCTCCTCAAGTGCATTGAGCTG
TCCTGCGGCTCCGTGAGGAAGATGAGGGATAGAAACCCCAAGGTGGCAGAGATCCCTTTC
AACTCAACCAATAAGTACCAGCTGTCCATCCACGAGCGAGAAGACAGCCCCCAGAGCCAC
GTGCTGGTGATGAAGGGGGCCCCTGAGCGCATCCTGGACCGTTGCTCCTCCATCCTGGTG
CAGGGCAAGGAGATCCCTCTGGACAAGGAGATGCAAGATGCCTTCCAGAATGCCTACCTG
GAGCTGGGAGGGCTCGGGGAGCGCGTCCTGGGCTTCTGTCAACTGAATCTGCCTTCTGCA
AAGTTTCCTCGGGGCTTCAAATTTGACACGGATGAGCTGAACTTTCCCACAGAGAAGCTC
TGCTTCGTGGGGCTCATGTCCATGATTGACCCTCCACGGGCTGCCGTTCCCGATGCTGTG
GGCAAGTGCCGGAGTGCAGGCATCAAGGTGATCATGGTGACCGGTGACCACCCCATCACA
GCCAAGGCCATTGCCAAAGGCGTGGGCATCATCTCAGAAGGCAACGAGACAGTGGAGGAC
ATTGCCGCCCGGCTCAACATTCCTGTTAGCCAAGTCAACCCCAGAGAAGCCAAGGCGTGT
GTGGTGCACGGCTCTGACCTGAAAGATATGACGTCGGAGCAGCTGGACGAGATCCTCAAG
AATCACACGGAGATCGTCTTTGCCCGGACGTCTCCTCAGCAGAAGCTCATCATCGTGGAG
GGCTGCCAGAGGCAGGGAGCCATTGTGGCGGTGACGGGGGATGGGGTGAATGACTCCCCG
GCGCTAAAGAAGGCGGACATTGGCATCGCCATGGGCATCGCTGGCTCCGACGTTTCTAAG
CAGGCCGCCGACATGATCCTGCTGGATGACAACTTTGCCTCCATCGTCACTGGCGTGGAG
GAGGGCCGCCTGATCTTTGACAACCTGAAGAAATCCATCGCCTACACCCTGACCAGTAAC
ATCCCCGAGATCACCCCTTTCCTGCTGTTCATCATCGCCAACATCCCCCTGCCTCTGGGC
ACCGTGACCATCCTCTGCATTGACCTGGGCACTGATATGGTCCCTGCCATCTCCTTGGCC
TATGAGGCAGCTGAGAGTGACATCATGAAGCGGCAGCCACGCAACCCGCAGACGGACAAG
CTGGTGAACGAGAGGCTCATCAGCATGGCCTATGGACAGATCGGGATGATCCAGGCTCTG
GGTGGCTTCTTCACCTACTTTGTGATCCTGGCAGAGAATGGTTTTCTACCTTCGCGGCTT
CTGGGAATCCGCCTGGACTGGGATGACCGGTCCATGAATGACTTGGAGGACAGCTACGGA
CAGGAGTGGACCTATGAACAGCGGAAGGTGGTGGAGTTCACATGCCACACGGCTTTCTTT
GCCAGCATTGTGGTCGTGCAATGGGCTGACCTCATCATCTGCAAGACCCGCCGCAACTCA
GTTTTCCAGCAGGGAATGAAAAACAAGATTCTGATTTTTGGGCTCCTGGAGGAGACAGCA
CTGGCGGCCTTTCTGTCTTACTGCCCGGGCATGGGCGTGGCTCTCCGAATGTACCCGCTC
AAGGTCACCTGGTGGTTCTGCGCCTTCCCCTACAGTCTCCTTATCTTCATCTACGATGAG
GTCCGAAAGCTGATCCTGCGGCGATATCCGGGTGGCTGGGTGGAGAAGGAGACCTACTAC
TGA
Enzyme 24 GenBank Gene ID BC133297 Link Image
Enzyme 24 GeneCard ID ATP1A2 Link Image
Enzyme 24 GenAtlas ID Not Available
Enzyme 24 HGNC ID Not Available
Enzyme 24 Chromosome Location Chromosome:1
Enzyme 24 Locus 1q21-q23
Enzyme 24 SNPs SNPJam Report Link Image
Enzyme 24 General References Not Available
Enzyme 24 Metabolite References Not Available
Enzyme 25 [top]
Enzyme 25 ID 159
Enzyme 25 Name 5'-nucleotidase
Enzyme 25 Synonyms
  1. Ecto-5'-nucleotidase
  2. 5'-NT
  3. CD73 antigen
Enzyme 25 Gene Name NT5E
Enzyme 25 Protein Sequence >5'-nucleotidase
MNPGAARTPALRILALGALLWPAARPWELTILHTNDVHSRLEQTSEDSSKCVNASRCVGG
VARLATKVHQIRRAEPHVLLLDAGDQYQGTIWFTVYKGTEVAHFMNALGYDAMALGNHEF
DNGVEGLIDPLLKEVNFPILSANIKAKGPLASKISGLYSPYKILTVGDEVVGIVGYTSKE
TPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEVDKLIAQKVKGVDVVV
GGHSNTFLYTGNPPSKEVPAGQYPFIVTSDDGRKVPVVQAYAFGKYLGYLKVEFDEKGNV
VTSHGNPILLNSSIPEDPNIKADINKWRVKLDNYSTQELGKTIVYLDGTAQSCRFRECNM
GNLICDAMINNNLRHPDEMSWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGT
FDLVQLKGSTLKKAFEHSVHRYGQATGEFLQVGGIHVVYDISRNPGDRVVKLEVLCTQCR
VPSYEPLRMDKVYKVILPSFLVSGGDGFQMIKDEKIKHDSGDQDINVVSGYISKMKVLYP
AVEGRIQFSAGSHCCGSFSLIFLSVLAVIIILYQ
Enzyme 25 Number of Residues 574
Enzyme 25 Molecular Weight 62965.8
Enzyme 25 Theoretical pI 6.94
Enzyme 25 GO Classification
Function
Process
Component
Enzyme 25 General Function Nucleotide transport and metabolism
Enzyme 25 Specific Function Hydrolyzes extracellular nucleotides into membrane permeable nucleosides
Enzyme 25 Pathways Not Available
Enzyme 25 Reactions Not Available
Enzyme 25 Pfam Domain Function
Enzyme 25 Signals
  • 1-26
Enzyme 25 Transmembrane Regions
  • None
Enzyme 25 Essentiality Not Available
Enzyme 25 GenBank ID Protein 285642 Link Image
Enzyme 25 UniProtKB/Swiss-Prot ID Q05927 Link Image
Enzyme 25 UniProtKB/Swiss-Prot Entry Name 5NTD_BOVIN Link Image
Enzyme 25 PDB ID Not Available
Enzyme 25 Cellular Location Not Available
Enzyme 25 Gene Sequence >1725 bp
ATGAATCCCGGAGCGGCTCGCACCCCGGCGCTGAGGATCCTGCCGCTGGGCGCGTTGCTG
TGGCCCGCGGCGCGCCCCTGGGAGCTCACCATCTTGCACACCAACGACGTACACAGCCGC
CTGGAGCAGACGAGTGAGGACTCGAGCAAGTGTGTCAACGCCAGCCGCTGCGTGGGCGGC
GTGGCACGGCTTGCCACCAAGGTGCACCAGATCCGCCGCGCCGAGCCCCACGTGCTGCTG
CTCGACGCCGGCGACCAGTACCAGGGCACCATCTGGTTCACCGTGTACAAGGGCACCGAG
GTGGCGCACTTCATGAACGCCCTGGGTTATGAGTCCATGGCACTGGGAAATCATGAATTT
GATAATGGTGTGGAAGGCCTGATTGATCCACTACTCAAAGAGGTCAATTTTCCAATTCTG
AGCGCAAACATTAAAGCCAAGGGGCCTCTAGCGTCTAAAATTTCAGGACTTTATTCACCA
TATAAAATTCTTACTGTTGGTGATGAAGTTGTGGGGATTGTTGGATACACTTCAAAGGAA
ACCCCTTTCCTCTCAAATCCAGGAACGAATTTAGTATTCGAAGATGAAATCACTGCATTG
CAACCAGAAGTAGATAAGTTAAAAACTCTAAATGTGAACAAAATTATTGCACTGGGACAC
TCTGGTTTTGAAGTGGATAAACTCATTGCTCAGAAAGTGAAGGGTGTGGATGTGGTGGTG
GGAGGACATTCCAACACGTTTCTCTACACAGGCAATCCACCTTCCAAAGAGGTGCCAGCA
GGGCAGTACCCATTCATAGTCACTTCTGATGATGGACGGAAGGTTCCTGTGGTCCAGGCC
TATGCTTTTGGCAAATACCTAGGCTATTTGAAGGTTGAGTTTGATGAAAAAGGAAATGTT
GTCACTTCACATGGAAATCCCATTCTTCTCAACAGCAGCATCCCAGAAGATCCAAACATA
AAAGCAGACATTAACAAATGGCGGGTAAAATTAGATAACTATTCAACCCAGGAATTGGGG
AAAACAATTGTCTATCTGGATGGTACTGCTCAGTCCTGCCGCTTTCGAGAATGCAACATG
GGCAATCTGATTTGTGATGCTATGATTAACAACAACCTGAGACACCCGGATGAGATGTCC
TGGAACCATGTGTCCATGTGCATTTTAAATGGAGGTGGCATCCGGTCGCCCATTGACGAG
CGGAACAATGGCACGATTACCTGGGAGAACCTGGCTGCTGTGTTGCCCTTTGGAGGCACC
TTTGACCTGGTCCAGTTAAAAGGCTCCACCCTGAAGAAGGCCTTCGACGACACGGTGCAC
CGCTATGGCCAGCGCACAGGCGAGTTTCTGCAGGTGGGAGGAATTCACGTGGTGTATGAT
ATTTCCCGAAACCCTGGGGACAGGGTGGTCAAGTTAGAGGTTCTTTGCACCCAGTGTCGT
GTGCCCAGTTATGAGCCTCTTAGAATGGATAAGGTGTACAAGGTGATCCTCCCAAGCTTC
CTTGTCAGTGGTGGAGACGGATTCCAGATGATAAAAGATGAAAAGATAAAACATGACTCT
GGTGACCAAGATATCAACGTGGTTTCTGGATACATCTCAAAAATGAAAGTGCTTTATCCA
GCAGTTGAAGGTCGGATCCAGTTTTCTGCAGGAAGTCATTGCTGTGGAAGTTTTTCTTTA
ATATTTCTTTCAGTTTTGGCAGTGATCATTATTTTATACCAATAG
Enzyme 25 GenBank Gene ID D14541 Link Image
Enzyme 25 GeneCard ID NT5E Link Image
Enzyme 25 GenAtlas ID Not Available
Enzyme 25 HGNC ID Not Available
Enzyme 25 Chromosome Location Chromosome:6
Enzyme 25 Locus 6q14-q21
Enzyme 25 SNPs SNPJam Report Link Image
Enzyme 25 General References
  1. [PubMed Link Image]
Enzyme 25 Metabolite References Not Available
Enzyme 26 [top]
Enzyme 26 ID 160
Enzyme 26 Name Dual specificity protein phosphatase 26
Enzyme 26 Synonyms Not Available
Enzyme 26 Gene Name DUSP26
Enzyme 26 Protein Sequence >Dual specificity protein phosphatase 26
MCPGNWLWASVTFMARFSRSGSRSPVRVRGALEEPPAVQHPFLNVFELERLLYTGKTACN
HADEVWPGLYLGDQEIANNHRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHD
SPAFDMSVHFQAAADFIHRALSQPGGRILVHCAVGVSRSATLVLAYLMLYHRLTLVEAIK
KVKDHRGIIPNRGFLRQLLALDRRLRQGLEA
Enzyme 26 Number of Residues 211
Enzyme 26 Molecular Weight 23767.1
Enzyme 26 Theoretical pI 9.97
Enzyme 26 GO Classification
Function
Process
Component
Enzyme 26 General Function Signal transduction mechanisms
Enzyme 26 Specific Function Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity
Enzyme 26 Pathways Not Available
Enzyme 26 Reactions Not Available
Enzyme 26 Pfam Domain Function
Enzyme 26 Signals
  • None
Enzyme 26 Transmembrane Regions
  • None
Enzyme 26 Essentiality Not Available
Enzyme 26 GenBank ID Protein 109659353 Link Image
Enzyme 26 UniProtKB/Swiss-Prot ID Q17QJ3 Link Image
Enzyme 26 UniProtKB/Swiss-Prot Entry Name DUS26_BOVIN Link Image
Enzyme 26 PDB ID Not Available
Enzyme 26 Cellular Location Not Available
Enzyme 26 Gene Sequence >636 bp
ATGTGTCCCGGCAACTGGCTCTGGGCTTCGGTGACATTCATGGCCCGCTTCTCCCGGAGC
GGCTCGAGGTCTCCAGTCCGCGTGAGAGGCGCCCTGGAGGAGCCGCCCGCCGTCCAGCAC
CCCTTCCTCAACGTCTTCGAGTTGGAGAGGCTGCTGTACACCGGGAAGACCGCCTGTAAC
CACGCCGACGAGGTCTGGCCAGGCCTCTACCTCGGAGACCAGGAAATAGCCAACAACCAC
CGGGAGCTGCGTCGCCTGGGCATCACGCACGTCCTCAACGCCTCTCACAGCCGGTGGCGA
GGGACGCCCGAAGCCTACGAGGGGCTGGGCATCCGCTACCTGGGTGTCGAGGCCCATGAC
TCGCCGGCCTTCGACATGAGTGTCCACTTCCAGGCAGCCGCTGACTTCATCCACCGGGCG
CTGAGCCAGCCAGGAGGGAGGATCCTGGTGCACTGCGCCGTGGGAGTGAGCCGCTCGGCC
ACCCTGGTGCTGGCCTACCTCATGCTGTACCACCGCCTCACCCTTGTGGAGGCCATCAAG
AAAGTCAAGGACCACCGAGGCATCATCCCCAACCGGGGCTTCCTGAGGCAGCTCCTGGCC
TTGGACCGCAGGCTGCGGCAGGGGCTGGAGGCGTGA
Enzyme 26 GenBank Gene ID BC118329 Link Image
Enzyme 26 GeneCard ID DUSP26 Link Image
Enzyme 26 GenAtlas ID Not Available
Enzyme 26 HGNC ID Not Available
Enzyme 26 Chromosome Location Chromosome:8
Enzyme 26 Locus 8p12
Enzyme 26 SNPs SNPJam Report Link Image
Enzyme 26 General References Not Available
Enzyme 26 Metabolite References Not Available
Enzyme 27 [top]
Enzyme 27 ID 161
Enzyme 27 Name Phosphorylase
Enzyme 27 Synonyms Not Available
Enzyme 27 Gene Name PYGM
Enzyme 27 Protein Sequence >Phosphorylase
MSRPLTDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAYTV
RDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYIGRTLQNTMVNLALENACDEATYQLGLDM
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEA
DDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVN
TMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDIIRRFKSSKFGCLDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDQERL
EWEKAWEVTVKTCAYTNHTVLPEALERWPVHLIETLLPRHLQIIYEINQRFLNRVAAAFP
GDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKF
QNKTNGITPRRWLVMCNPGLAEIIAERIGEEYIADLDQLRKLLSYVDDESFIRDVAKVKQ
ENKLKFSAYLEKEYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKKEPNKFFV
PRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVIPA
ADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVE
RLDHKGYNAQEYYDRIPELRHVIDQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYEE
YVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPTRQRMPAPDE
KI
Enzyme 27 Number of Residues 842
Enzyme 27 Molecular Weight 97287.7
Enzyme 27 Theoretical pI 7.14
Enzyme 27 GO Classification
Function
Process
Component
Enzyme 27 General Function Carbohydrate transport and metabolism
Enzyme 27 Specific Function Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
Enzyme 27 Pathways Not Available
Enzyme 27 Reactions Not Available
Enzyme 27 Pfam Domain Function
Enzyme 27 Signals
  • None
Enzyme 27 Transmembrane Regions
  • None
Enzyme 27 Essentiality Not Available
Enzyme 27 GenBank ID Protein 154426116 Link Image
Enzyme 27 UniProtKB/Swiss-Prot ID B0JYK6 Link Image
Enzyme 27 UniProtKB/Swiss-Prot Entry Name B0JYK6_BOVIN Link Image
Enzyme 27 PDB ID 1XL1 Link Image
Enzyme 27 PDB File Show
Enzyme 27 3D Structure
Enzyme 27 Cellular Location Not Available
Enzyme 27 Gene Sequence >2529 bp
ATGTCCCGGCCCCTGACAGACCAGGAGAAGAGAAAGCAGATCAGCGTGCGTGGCCTGGCC
GGTGTGGAGAATGTGACTGAGCTGAAGAAGAACTTCAACCGGCACCTACACTTCACCCTT
GTGAAGGACCGCAATGTGGCCACCCCGCGAGACTACTACTTCGCGCTGGCCTACACGGTG
CGAGACCACCTCGTGGGCCGCTGGATCCGCACGCAGCAGCACTACTACGAGAAGGACCCC
AAGAGGATCTACTACCTGTCTCTGGAATTCTACATCGGCCGGACGCTGCAGAACACCATG
GTGAACCTGGCGTTGGAGAATGCCTGTGACGAGGCCACCTATCAGCTGGGCCTAGACATG
GAGGAGCTGGAGGAAATCGAGGAGGATGCAGGGCTGGGCAACGGGGGCCTGGGCCGGCTG
GCGGCCTGCTTTCTGGACTCAATGGCAACACTGGGCCTGGCTGCCTATGGCTATGGGATC
CGCTATGAGTTTGGGATTTTTAACCAGAAGATCTCTGGGGGTTGGCAGATGGAGGAAGCT
GATGACTGGCTTCGCTACGGCAACCCCTGGGAGAAGGCCCGTCCTGAGTTCACGCTGCCG
GTGCACTTCTATGGCCGAGTGGAACACACCAGCCAGGGGGCCAAGTGGGTGGACACACAG
GTGGTGCTGGCCATGCCCTACGACACACCCGTGCCTGGCTACCGCAACAACGTGGTCAAC
ACCATGCGCCTGTGGTCTGCCAAAGCCCCCAACGACTTCAACCTCAAGGACTTCAATGTC
GGTGGCTACATCCAGGCCGTGCTGGACCGCAACCTGGCTGAGAACATCTCACGGGTCCTG
TACCCCAACGACAACTTCTTTGAGGGGAAGGAGCTGCGGCTGAAGCAGGAGTACTTCGTA
GTGGCTGCCACGCTCCAGGACATCATCCGCCGCTTCAAGTCCTCCAAGTTTGGCTGCCTC
GACCCCGTGCGCACCAACTTCGATGCCTTCCCAGATAAGGTGGCCATCCAGCTCAATGAC
ACCCACCCCTCCTTGGCCATCCCTGAGCTGATGAGGATTCTGGTGGACCAGGAGCGCCTG
GAGTGGGAAAAGGCATGGGAAGTGACTGTGAAGACTTGTGCCTACACCAACCACACGGTG
CTGCCCGAGGCCCTGGAGCGCTGGCCTGTGCACCTCATAGAGACCCTGCTGCCGCGGCAC
CTCCAGATCATCTATGAAATCAACCAGCGCTTCCTTAACCGGGTGGCAGCCGCGTTCCCA
GGGGATGTGGACCGACTGCGGCGCATGTCGCTGGTGGAGGAGGGCGCGGTGAAGCGCATC
AATATGGCACACCTGTGCATCGCCGGGTCTCATGCCGTCAATGGCGTGGCTCGCATCCAC
TCGGAGATCCTCAAGAAGACCATCTTCAAGGACTTCTACGAGCTGGAGCCTCATAAGTTC
CAGAATAAGACCAATGGGATCACCCCTCGGCGCTGGTTGGTGATGTGTAACCCTGGGCTG
GCAGAGATCATTGCTGAGCGCATCGGAGAGGAATACATCGCAGACCTGGATCAGCTGCGC
AAACTGCTGTCCTATGTGGATGATGAATCCTTTATCCGGGATGTGGCCAAAGTGAAGCAG
GAAAACAAGTTAAAGTTTTCTGCATACCTGGAGAAGGAATACAAAGTCCACATCAACCCC
AACTCACTCTTCGATATCCAGGTGAAGCGGATTCACGAATATAAACGCCAGCTCCTCAAC
TGCCTCCATGTCATCACGCTGTACAACCGTATCAAGAAGGAACCCAATAAGTTTTTTGTG
CCTCGGACTGTGATGATTGGAGGGAAGGCTGCCCCTGGGTACCATATGGCCAAGATGATC
ATCAAACTCATCACAGCCATTGGGGATGTGGTCAACCACGACCCGGTGGTGGGAGACCGC
CTTCGTGTGATCTTCCTGGAGAACTACCGAGTCTCGCTGGCCGAGAAAGTGATCCCGGCT
GCTGACCTCTCCGAGCAGATCTCTACTGCGGGCACTGAAGCCTCAGGCACTGGCAACATG
AAGTTCATGCTCAACGGGGCTCTGACCATTGGCACCATGGACGGGGCCAACGTGGAGATG
GCGGAAGAGGCGGGAGAGGAGAACTTCTTCATCTTTGGCATGCGGGTGGAGGACGTGGAA
AGGCTTGACCATAAAGGGTACAATGCCCAGGAGTATTATGACCGGATTCCTGAGCTTCGG
CACGTCATTGACCAGCTGAGCAGTGGCTTCTTCTCCCCCAAACAGCCTGACCTATTCAAG
GACATTGTCAACATGCTCATGCACCATGACCGGTTTAAAGTCTTTGCGGATTATGAAGAG
TACGTTAAATGCCAGGAAAGAGTCAGTGCCTTGTACAAGAACCCGAGAGAGTGGACGCGG
ATGGTGATCCGGAACATAGCTACATCTGGCAAGTTCTCCAGTGACCGCACCATTGCCCAG
TACGCCAGGGAGATCTGGGGCGTGGAGCCGACCCGCCAGCGCATGCCGGCCCCGGATGAG
AAGATCTGA
Enzyme 27 GenBank Gene ID BC151314 Link Image
Enzyme 27 GeneCard ID PYGM Link Image
Enzyme 27 GenAtlas ID Not Available
Enzyme 27 HGNC ID Not Available
Enzyme 27 Chromosome Location Chromosome:1
Enzyme 27 Locus 11q12-q13.2
Enzyme 27 SNPs SNPJam Report Link Image
Enzyme 27 General References Not Available
Enzyme 27 Metabolite References Not Available
Enzyme 28 [top]
Enzyme 28 ID 162
Enzyme 28 Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Enzyme 28 Synonyms
  1. PFK-2/FBPase-2
  2. 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme
  3. 6-phosphofructo-2-kinase
  4. Fructose-2,6-bisphosphatase
Enzyme 28 Gene Name PFKFB2
Enzyme 28 Protein Sequence >6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
MSGNPASSSEQNNNSYETKASLRISEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLT
RYLNWIGVPTKVFNLGVYRRQAVKSYKSYDFFRHDNEEAMKIRKQCALVALKDVKAYLTE
ESGQIAVFDATNTTRERRDLILNFAEENSFKVFFVESVCDDPDVIAANILEVKVSSPDYP
ERNRENVMDDFLKRIECYKVTYQPLDPDSHDKDLSFIKVINVGQRFLVNKVQDYIQSKIV
YYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLKV
WTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLYR
YPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHT
IFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKSQTPVRMRRNSFTPLSSSNTIRRP
RNYSVGSRPLQPLSPLRALDTQEGADQPKTQAETSRAAHRLPSPAPPTSPS
Enzyme 28 Number of Residues 531
Enzyme 28 Molecular Weight 60810.7
Enzyme 28 Theoretical pI 8.41
Enzyme 28 GO Classification
Function
Process
Component
Enzyme 28 General Function Carbohydrate transport and metabolism
Enzyme 28 Specific Function Synthesis and degradation of fructose 2,6-bisphosphate
Enzyme 28 Pathways Not Available
Enzyme 28 Reactions Not Available
Enzyme 28 Pfam Domain Function
Enzyme 28 Signals
  • None
Enzyme 28 Transmembrane Regions
  • None
Enzyme 28 Essentiality Not Available
Enzyme 28 GenBank ID Protein 552322 Link Image
Enzyme 28 UniProtKB/Swiss-Prot ID P26285 Link Image
Enzyme 28 UniProtKB/Swiss-Prot Entry Name F262_BOVIN Link Image
Enzyme 28 PDB ID Not Available
Enzyme 28 Cellular Location Not Available
Enzyme 28 Gene Sequence >1596 bp
ATGTCCGGGAATCCTGCCTCTTCCTCAGAACAGAACAACAATAGCTATGAAACCAAAGCA
AGTCTCCGAATATCAGAGAAGAAATGTTCATGGGCATCTTACATGACAAACTCTCCAACC
CTCATCGTTATGATTGGCTTGCCAGCCCGTGGCAAAACCTACGTGTCCAAGAAACTTACA
CGCTACCTCAACTGGATTGGGGTGCCCACCAAAGTGTTTAATCTTGGGGTGTATCGGCGG
CAAGCAGTCAAGTCCTATAAGTCCTATGACTTCTTCCGGCATGACAACGAGGAGGCCATG
AAGATTCGCAAACAGTGTGCCCTGGTGGCACTGAAAGACGTGAAGGCGTATCTCACGGAG
GAGAGCGGGCAGATTGCGGTGTTTGATGCTACCAATACCACTCGAGAGAGGAGGGACTTG
ATTTTGAACTTTGCCGAGGAGAATTCTTTCAAGGTGTTCTTTGTGGAGTCCGTGTGCGAT
GATCCTGATGTCATTGCTGCCAACATCCTGGAGGTAAAGGTGTCGAGCCCCGACTACCCT
GAAAGGAACAGGGAGAATGTGATGGATGACTTCCTAAAGAGGATTGAGTGCTACAAAGTC
ACCTATCAACCCCTTGACCCAGACAGCCATGACAAGGATCTTTCTTTCATCAAGGTGATA
AACGTGGGCCAGAGATTTCTCGTGAACAAAGTCCAGGACTACATCCAGAGCAAGATCGTC
TACTACCTCATGAATATCCACGTCCACCCTCGCACCATCTACCTTTGCCGGCATGGAGAG
AGCGAGTTCAACCTCTTGGGGAAGATTGGGGGTGACTCAGGCCTCTCAGTGCGAGGAAAA
CAGTTTGCCCAGGCTCTAAGGAAGTTTCTGGAGGAACAGGAGATAGCAGACCTCAAAGTG
TGGACGAGCCAGTTGAAAAGGACTATCCAGACCGCAGAATCTCTGGGGGTGACCTACGAG
CAGTGGAAGATTCTGAACGAGATTGATGCTGGCGTGTGCGAGGAGATGACTTACGCGGAG
ATTCAGGAGCAGTATCCGGATGAGTTTGCGCTTCGAGATGAAGAGAAATATCTGTACCGA
TATCCTGGAGGGGAGTCATACCAGGACCTCGTGCAGCGGTTGGAGCCAGTCATCATGGAG
CTGGAGCGCCAGGGCAATGTCCTCGTTATCTCCCACCAGGCTGTCATGCGCTGCCTCCTG
GCCTACTTCTTGGACAAGGGTGCAGATGAGCTACCATACCTGAGGTGCCCTCTCCATACC
ATCTTCAAACTTACTCCTGTGGCCTACGGGTGCAAAGTGGAAACAATTAAACTCAATGTG
GAGGCTGTGAACACGCACCGTGACAAGCCAACTAACAACTTTCCCAAGAGCCAAACCCCT
GTAAGGATGAGAAGGAACAGCTTTACGCCTCTGTCCAGTTCGAATACAATCAGGCGTCCA
AGAAATTACAGTGTTGGGAGCCGGCCCCTCCAGCCCCTCAGCCCGCTCCGTGCCCTGGAC
ACGCAAGAAGGGGCCGACCAGCCGAAGACCCAAGCAGAGACCTCGCGGGCTGCACACAGG
CTCCCGTCTCCAGCGCCCCCCACGTCGCCCTCCTGA
Enzyme 28 GenBank Gene ID M34241 Link Image
Enzyme 28 GeneCard ID PFKFB2 Link Image
Enzyme 28 GenAtlas ID Not Available
Enzyme 28 HGNC ID Not Available
Enzyme 28 Chromosome Location Chromosome:1
Enzyme 28 Locus 1q31
Enzyme 28 SNPs SNPJam Report Link Image
Enzyme 28 General References
  1. [PubMed Link Image]
Enzyme 28 Metabolite References Not Available
Enzyme 29 [top]
Enzyme 29 ID 163
Enzyme 29 Name Ectonucleoside triphosphate diphosphohydrolase 1
Enzyme 29 Synonyms
  1. NTPDase 1
  2. Ecto-ATP diphosphohydrolase
  3. ATPDase
  4. Lymphoid cell activation antigen
  5. Ecto-apyrase
  6. CD39 antigen
Enzyme 29 Gene Name ENTPD1
Enzyme 29 Protein Sequence >Ectonucleoside triphosphate diphosphohydrolase 1
MEDRRESELKVFCSKNILSILGFSCIIAVIALLALGLTQNKALPENVKFGIVLDAGSSHT
SLYIYRWPAEKENDTGVVTQIEESNVKGPGISGFAKKVNEINVYLTACMERAQKVIPSIQ
HMETPVYLGATAGMRLLRMENKQMADKILAAVASSISEYPFDFQGARIISGQEEGAYGWI
TVNYLLGKFTQKLSWFNLKPSKDDTQETYGALDLGGASTQITFVPQNETTESPNNNLYFR
LYGKNYSVYTHSFLCYGKDQALLQKLALGLQGTNGIIHEPCFHSRYMRKIKMSVLNEGFC
TKRHELNSSFYPLVDIEIRGAGNFQRCRQSIIQLFNTSYCPYSSCSFNGVFLPPLHGQFG
AFSAFYYVMEFLNLTSEESVSVEQLTEKLEEFCAQRWEEVQKNFGEVKEKYLSEYCFSGT
YILVLLLNGYHFTAESWKNIHFMNKVRSTDVGWTLGYMLNLTNKIPAEEPMSPPLPHSTY
VFLMVLFSLILLAVIIVGIVVFHKPSYFWKDMV
Enzyme 29 Number of Residues 513
Enzyme 29 Molecular Weight 58113.4
Enzyme 29 Theoretical pI 6.88
Enzyme 29 GO Classification
Function
Process
Component
Enzyme 29 General Function Involved in ATP binding
Enzyme 29 Specific Function In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well
Enzyme 29 Pathways Not Available
Enzyme 29 Reactions Not Available
Enzyme 29 Pfam Domain Function
Enzyme 29 Signals
  • None
Enzyme 29 Transmembrane Regions
  • 17-37 482-502
Enzyme 29 Essentiality Not Available
Enzyme 29 GenBank ID Protein 2240205 Link Image
Enzyme 29 UniProtKB/Swiss-Prot ID O18956 Link Image
Enzyme 29 UniProtKB/Swiss-Prot Entry Name ENTP1_BOVIN Link Image
Enzyme 29 PDB ID Not Available
Enzyme 29 Cellular Location Not Available
Enzyme 29 Gene Sequence >1542 bp
ATGGAAGATAGAAGGGAATCTGAACTGAAGGTATTTTGCTCTAAAAACATACTGAGCATA
CTTGGTTTCTCCTGCATCATCGCTGTGATAGCATTGCTCGCTCTGGGGCTGACCCAGAAC
AAAGCACTGCCAGAAAATGTTAAGTTTGGGATTGTGCTGGATGCGGGCTCCTCTCATACG
AGTTTGTACATCTATAGATGGCCGGCAGAGAAGGAGAATGACACGGGGGTGGTGACTCAG
ATAGAAGAATCGAACGTTAAAGGTCCCGGAATCTCAGGCTTTGCTAAAAAAGTAAATGAA
ATCAATGTTTATCTGACGGCATGCATGGAAAGAGCCCAGAAAGTGATTCCGTCAATCCAG
CACATGGAAACACCTGTGTACCTGGGAGCCACGGCCGGCATGCGGTTGCTCCGGATGGAA
AATAAACAGATGGCAGACAAGATCCTGGCTGCAGTTGCAAGCAGCATCAGCGAGTACCCC
TTTGACTTCCAAGGTGCCAGAATCATCAGTGGCCAGGAGGAAGGTGCCTATGGCTGGATT
ACTGTCAACTATTTGCTGGGCAAATTCACTCAGAAATTGAGTTGGTTTAACCTGAAGCCA
AGCAAAGACGACACTCAGGAAACCTATGGAGCTTTAGACCTTGGGGGAGCCTCTACACAA
ATCACTTTTGTGCCCCAAAATGAAACGACCGAGTCTCCAAACAACAACCTGTACTTCCGC
CTCTATGGCAAGAACTACAGTGTATACACACACAGCTTCCTGTGCTATGGGAAGGACCAA
GCACTTTTGCAGAAACTGGCCCTGGGACTTCAGGGTACAAATGGAATCATCCATGAGCCA
TGCTTTCACTCAAGATACATGAGGAAAATAAAGATGAGCGTCTTAAACGAAGGTTTCTGT
ACCAAGAGACATGAGTTGAATTCTTCATTTTATCCACTCGTTGACATTGAAATCCGTGGC
GCTGGAAACTTCCAACGATGTCGGCAAAGCATCATTCAACTCTTTAACACCAGTTACTGC
CCTTACTCCAGTTGCTCCTTCAATGGGGTTTTCTTGCCGCCACTCCATGGGCAGTTTGGG
GCATTTTCAGCTTTTTACTATGTGATGGAGTTTTTAAACCTTACATCAGAGGAATCAGTA
TCTGTGGAACAGTTGACTGAGAAGTTGGAAGAGTTCTGCGCACAGCGTTGGGAAGAGGTG
CAGAAGAATTTTGGTGAAGTGAAGGAGAAATACCTGAGTGAATACTGCTTTTCTGGCACC
TACATCCTGGTTCTCCTCCTGAATGGCTACCATTTTACAGCTGAGTCCTGGAAAAATATT
CACTTCATGAACAAGGTCCGGAGCACCGACGTTGGGTGGACTTTGGGCTACATGCTGAAC
CTGACCAACAAGATTCCAGCTGAAGAGCCAATGTCCCCACCCCTCCCCCACTCCACCTAT
GTCTTCCTCATGGTCCTCTTCTCCCTGATCCTGCTCGCAGTGATCATCGTAGGCATAGTT
GTCTTTCACAAGCCTTCGTATTTCTGGAAAGACATGGTATAG
Enzyme 29 GenBank Gene ID AF005940 Link Image
Enzyme 29 GeneCard ID ENTPD1 Link Image
Enzyme 29 GenAtlas ID Not Available
Enzyme 29 HGNC ID Not Available
Enzyme 29 Chromosome Location Chromosome:1
Enzyme 29 Locus 10q24
Enzyme 29 SNPs SNPJam Report Link Image
Enzyme 29 General References
  1. [PubMed Link Image]
Enzyme 29 Metabolite References Not Available
Enzyme 30 [top]
Enzyme 30 ID 164
Enzyme 30 Name Dynamin-1
Enzyme 30 Synonyms Not Available
Enzyme 30 Gene Name DNM1
Enzyme 30 Protein Sequence >Dynamin-1
MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI
NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD
LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL
QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA
RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDLAFEATVKKQVQKL
KEPSIKCVDMVVSELTATIRKCSEKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID
IELAYMNTNHEDFIGFANAQQRSNQMNKKKASGNQDEILVIRKGWLTINNIGIMKGGSKE
YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE
TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE
QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPTGRRSPTSSPT
PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP
PGVPSQPIGSGKSIPS
Enzyme 30 Number of Residues 856
Enzyme 30 Molecular Weight 96251.1
Enzyme 30 Theoretical pI 6.85
Enzyme 30 GO Classification
Function
Process
Component
Enzyme 30 General Function Involved in GTP binding
Enzyme 30 Specific Function Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis
Enzyme 30 Pathways Not Available
Enzyme 30 Reactions Not Available
Enzyme 30 Pfam Domain Function
Enzyme 30 Signals
  • None
Enzyme 30 Transmembrane Regions
  • None
Enzyme 30 Essentiality Not Available
Enzyme 30 GenBank ID Protein 115305212 Link Image
Enzyme 30 UniProtKB/Swiss-Prot ID Q08DF4 Link Image
Enzyme 30 UniProtKB/Swiss-Prot Entry Name DYN1_BOVIN Link Image
Enzyme 30 PDB ID Not Available
Enzyme 30 Cellular Location Not Available
Enzyme 30 Gene Sequence >2571 bp
ATGGGCAACCGTGGCATGGAGGATCTCATCCCGCTGGTCAACCGGCTGCAGGATGCCTTC
TCCGCCATCGGCCAGAACGCGGACCTTGACCTGCCGCAGATCGCCGTGGTGGGCGGCCAG
AGCGCCGGCAAGAGCTCGGTGCTCGAGAATTTCGTAGGCAGGGACTTCTTGCCCCGAGGA
TCTGGCATTGTCACGCGACGCCCCCTGGTCCTGCAGCTGGTCAATGCTACTACAGAATAT
GCCGAGTTTCTGCACTGCAAGGGGAAGAAATTCACTGACTTCGAAGAGGTGCGCCTGGAG
ATTGAGGCTGAGACCGACCGGGTGACCGGCACTAACAAGGGCATCTCTCCAGTGCCCATC
AACCTCCGCGTTTACTCGCCGCACGTGCTGAACCTGACCCTAGTGGACTTGCCTGGAATG
ACCAAGGTCCCGGTGGGGGACCAACCTCCTGACATCGAGTTCCAGATCCGGGACATGCTT
ATGCAGTTCGTCACCAAGGAGAACTGCCTCATCTTGGCCGTGTCCCCGGCCAACTCTGAC
CTGGCCAACTCTGATGCCCTCAAGGTCGCCAAGGAGGTGGACCCCCAGGGTCAGCGAACC
ATCGGGGTCATCACTAAGCTGGATCTGATGGACGAGGGCACAGATGCCCGCGATGTTTTG
GAGAACAAGCTGCTCCCGCTGCGCAGAGGCTACATTGGAGTCGTGAACCGAAGCCAGAAG
GACATCGATGGTAAGAAAGATATCACAGCTGCCTTGGCTGCTGAACGCAAGTTCTTCCTC
TCCCACCCTTCCTACCGCCACTTGGCTGACCGCATGGGCACGCCCTACCTGCAGAAGGTC
CTCAACCAGCAACTGACAAACCACATCCGGGACACGCTGCCAGGGCTGCGAAACAAACTC
CAGAGCCAGCTGCTGTCCATCGAGAAGGAGGTGGAGGAGTACAAAAACTTCCGCCCTGAT
GACCCAGCACGCAAGACCAAGGCTCTGCTGCAGATGGTCCAGCAGTTCGCTGTAGACTTT
GAGAAGCGCATTGAAGGCTCAGGGGACCAGATTGACACCTATGAACTGTCAGGGGGCGCC
CGCATCAACCGGATCTTCCATGAGCGCTTCCCTTTCGAGTTGGTCAAGATGGAGTTTGAC
GAGAAGGAACTCCGAAGGGAGATCAGCTATGCCATCAAGAATATCCATGGCATTAGGACG
GGCCTCTTCACACCTGACCTCGCTTTTGAAGCCACAGTGAAAAAGCAGGTGCAGAAGCTT
AAAGAGCCCAGTATCAAGTGTGTGGATATGGTAGTCAGTGAGCTCACGGCCACCATCAGA
AAGTGTAGTGAAAAGCTCCAGCAGTACCCCCGGCTGCGGGAGGAGATGGAGCGCATTGTG
ACCACCCACATCCGAGAGCGCGAGGGTCGCACCAAGGAGCAGGTCATGCTCCTCATCGAT
ATTGAGCTGGCTTACATGAATACCAACCATGAGGACTTCATAGGCTTTGCCAATGCTCAG
CAGAGAAGCAACCAGATGAACAAGAAGAAGGCTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGGAAGGGCTGGCTGACCATCAACAACATCGGCATCATGAAGGGAGGCTCCAAGGAG
TATTGGTTTGTGCTGACTGCCGAGAATCTGTCCTGGTACAAGGATGACGAGGAGAAAGAG
AAGAAGTACATGCTGTCCGTGGATAACCTGAAGTTGCGGGACGTGGAGAAGGGCTTCATG
TCCAGCAAGCACATCTTTGCCCTCTTCAACACGGAGCAGAGGAATGTCTACAAGGATTAT
CGGCAGCTGGAGCTGGCCTGCGAGACACAGGAGGAGGTGGATAGCTGGAAGGCCTCCTTT
CTAAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGTGAGACGGAG
GAGAACGGCTCGGACAGCTTCATGCACTCCATGGACCCACAGCTGGAGCGGCAGGTGGAG
ACCATCCGGAACTTGGTGGATTCATACATGGCCATCGTCAACAAGACTGTCCGGGACCTC
ATGCCCAAGACGATCATGCATCTCATGATCAACAATACCAAGGAATTCATCTTCTCGGAG
CTGCTGGCCAACCTGTATTCGTGCGGGGACCAGAACACACTGATGGAGGAGTCGGCCGAA
CAGGCACAGCGGCGTGACGAGATGCTGCGCATGTACCACGCACTGAAAGAGGCGCTCAGC
ATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCTGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGACCGGACGCAGGTCACCCACGTCCAGCCCCACG
CCGCAGCGCCGAGCCCCTGCCGTGCCCCCAGCCCGGCCCGGGTCGCGGGGCCCTGCTCCT
GGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGAGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCCTTCGGTCCTCCCCCCCAGGTGCCCTCGCGCCCCAACCGCGCCCCG
CCCGGGGTCCCCAGCCAGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGA
Enzyme 30 GenBank Gene ID BC123778 Link Image
Enzyme 30 GeneCard ID DNM1 Link Image
Enzyme 30 GenAtlas ID Not Available
Enzyme 30 HGNC ID Not Available
Enzyme 30 Chromosome Location Chromosome:9
Enzyme 30 Locus 9q34
Enzyme 30 SNPs SNPJam Report Link Image
Enzyme 30 General References Not Available
Enzyme 30 Metabolite References Not Available
Enzyme 31 [top]
Enzyme 31 ID 165
Enzyme 31 Name Glucose-6-phosphatase
Enzyme 31 Synonyms
  1. G-6-Pase
  2. G6Pase
Enzyme 31 Gene Name G6PC
Enzyme 31 Protein Sequence >Glucose-6-phosphatase
MEKGMNVLHDFGIQSTHYLQVNYQNSQDWFILVSVIADLRNAFYVLFPIWFHLREAVGIK
LLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSAPLIKQFPVTCETGPGSPSGHA
MGTAGVYYVMVTSTLSIFRGKKKPTYRFRCLNVMLWLGFWVVQLNVCLSRIYLAAHFPHQ
VVAGVLSGIAVAETFRHIQSIYNASLKKYFLITCFLFSFAIGFYLLLKWLGVDLLWTLEK
AKRRCERPEWVHIDTTPFASLLKNLGTLFGLGLALNSSMYRESCKGKLSKWFPFRLSCIV
ASLVLLHLFDSLKPPSQIELIFYVLSFCKSAAVPLASVSLIPYCLAWVLGQPNKKTV
Enzyme 31 Number of Residues 357
Enzyme 31 Molecular Weight 40826.9
Enzyme 31 Theoretical pI 9.66
Enzyme 31 GO Classification
Function
Process
Component
Enzyme 31 General Function Involved in glucose-6-phosphatase activity
Enzyme 31 Specific Function Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels
Enzyme 31 Pathways
  • Carbohydrate biosynthesis
  • gluconeogenesis
Enzyme 31 Reactions Not Available
Enzyme 31 Pfam Domain Function
Enzyme 31 Signals
  • None
Enzyme 31 Transmembrane Regions
  • 29-49 61-81 118-138 148-168 171-191 210-230 255-275 292-312 321-341
Enzyme 31 Essentiality Not Available
Enzyme 31 GenBank ID Protein 88954372 Link Image
Enzyme 31 UniProtKB/Swiss-Prot ID Q29RU6 Link Image
Enzyme 31 UniProtKB/Swiss-Prot Entry Name G6PC_BOVIN Link Image
Enzyme 31 PDB ID Not Available
Enzyme 31 Cellular Location Not Available
Enzyme 31 Gene Sequence >1074 bp
ATGGAGAAGGGAATGAACGTTCTACATGACTTTGGGATCCAGTCAACACACTACCTCCAG
GTGAATTACCAGAACTCCCAGGATTGGTTCATCTTGGTGTCTGTGATTGCAGATCTCAGG
AATGCCTTTTATGTCCTCTTCCCCATTTGGTTCCATCTTCGAGAAGCTGTGGGCATCAAA
CTCCTCTGGGTAGCTGTGATTGGAGATTGGCTCAACCTCGTCTTTAAGTGGATTCTCTTT
GGACAGCGCCCATACTGGTGGGTTTTGGATACCGACTACTACAGCAACACCTCGGCACCG
CTGATAAAGCAGTTCCCGGTCACCTGTGAGACCGGCCCAGGGAGTCCCTCTGGCCACGCC
ATGGGTACAGCAGGTGTATACTATGTGATGGTCACATCCACCCTCTCTATCTTTCGTGGA
AAGAAAAAGCCAACCTACAGATTTCGGTGCTTGAATGTCATGTTGTGGTTGGGATTCTGG
GTCGTGCAACTGAATGTCTGCCTGTCACGAATCTACCTTGCTGCTCATTTTCCCCATCAA
GTTGTTGCTGGAGTCTTGTCAGGCATTGCGGTTGCTGAGACTTTCCGCCACATCCAGAGC
ATCTACAATGCCAGTCTCAAGAAGTACTTTCTCATCACCTGCTTCCTGTTCAGTTTCGCC
ATTGGATTTTACCTGCTGTTAAAGTGGCTGGGGGTCGACCTGCTGTGGACTCTAGAGAAA
GCCAAGCGAAGGTGTGAGCGGCCGGAGTGGGTCCACATTGATACAACGCCCTTTGCCAGC
CTCCTCAAGAATCTGGGGACCCTCTTTGGCTTGGGTCTGGCTCTCAACTCTAGCATGTAC
CGGGAGAGCTGCAAGGGCAAGCTCAGCAAGTGGTTCCCGTTTCGCCTCAGCTGCATCGTG
GCCTCCCTCGTCCTCCTGCACCTCTTTGACTCTTTGAAACCCCCCTCCCAAATCGAGCTG
ATCTTCTATGTCCTGTCCTTCTGCAAGAGTGCAGCGGTGCCCCTGGCATCTGTCAGCCTC
ATCCCCTACTGCCTCGCCTGGGTGCTGGGCCAGCCCAACAAGAAGACTGTGTAA
Enzyme 31 GenBank Gene ID BC114011 Link Image
Enzyme 31 GeneCard ID G6PC Link Image
Enzyme 31 GenAtlas ID Not Available
Enzyme 31 HGNC ID Not Available
Enzyme 31 Chromosome Location Chromosome:1
Enzyme 31 Locus 17q21
Enzyme 31 SNPs SNPJam Report Link Image
Enzyme 31 General References Not Available
Enzyme 31 Metabolite References Not Available
Enzyme 32 [top]
Enzyme 32 ID 166
Enzyme 32 Name Beta-adrenergic receptor kinase 2
Enzyme 32 Synonyms
  1. Beta-ARK-2
  2. G-protein-coupled receptor kinase 3
Enzyme 32 Gene Name ADRBK2
Enzyme 32 Protein Sequence >Beta-adrenergic receptor kinase 2
MADLEAVLADVSYLMAMEKSKATPAARASKKIVLPEPSIRSVMQKYLEERHEITFDKIFN
QRIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLENEEDRLCRSRQIYDTYIMKELLSC
SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGSIFQKFMESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDVFSPE
LKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVAETVYEAVNADTDKIEARK
RAKNKQLGHEEDYALGRDCIVHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSL
LTMEQIVSVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTETFMEAQRLLRR
APKFLNKSRSAVVELSKPPLCHRNSNGL
Enzyme 32 Number of Residues 688
Enzyme 32 Molecular Weight 79803.3
Enzyme 32 Theoretical pI 7.56
Enzyme 32 GO Classification
Function
Process
Component
Enzyme 32 General Function Involved in ATP binding
Enzyme 32 Specific Function Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them
Enzyme 32 Pathways Not Available
Enzyme 32 Reactions Not Available
Enzyme 32 Pfam Domain Function
Enzyme 32 Signals
  • None
Enzyme 32 Transmembrane Regions
  • None
Enzyme 32 Essentiality Not Available
Enzyme 32 GenBank ID Protein 162735 Link Image
Enzyme 32 UniProtKB/Swiss-Prot ID P26818 Link Image
Enzyme 32 UniProtKB/Swiss-Prot Entry Name ARBK2_BOVIN Link Image
Enzyme 32 PDB ID Not Available
Enzyme 32 Cellular Location Not Available
Enzyme 32 Gene Sequence >2067 bp
ATGGCGGACCTGGAGGCCGTGCTGGCCGATGTCAGCTACCTGATGGCGATGGAGAAGAGC
AAGGCGACCCCGGCCGCCCGCGCCAGCAAGAAGATCGTCCTGCCCGAGCCCAGTATCCGG
AGCGTGATGCAGAAGTATCTTGAGGAGAGACACGAAATCACCTTTGACAAGATTTTTAAT
CAGAGAATTGGTTTCTTGCTATTTAAAGATTTTTGTTTGAATGAAATTAATGAAGCTGTA
CCTCAGGTGAAGTTTTATGAAGAGATAAAAGAATATGAAAAGCTTGAGAATGAGGAAGAT
CGCCTTTGTAGAAGTCGACAGATTTATGACACTTACATCATGAAGGAGCTGCTGTCGTGT
TCACATCCATTCTCAAAGCAAGCCGTAGAACACGTACAAAGTCATCTGTCCAAGAAACAA
GTGACATCAACTCTTTTTCAGCCATACATAGAAGAAATTTGTGAAAGTCTCCGAGGCAGC
ATTTTTCAAAAATTCATGGAAAGTGACAAGTTTACTAGATTTTGTCAGTGGAAAAACGTG
GAATTAAATATCCATTTGACCATGAATGATTTCAGCGTGCATCGGATCATTGGACGAGGA
GGATTCGGTGAAGTATACGGTTGCAGGAAAGCAGACACTGGAAAGATGTATGCAATGAAA
TGCTTGGATAAGAAGAGAATCAAGATGAAACAGGGAGAAACCTTAGCCTTAAATGAAAGG
ATCATGTTGTCCCTGGTGAGCACAGGAGATTGCCCTTTCATCGTCTGTATGACCTATGCC
TTCCACACTCCAGATAAACTGTGCTTCATCTTGGATCTGATGAACGGGGGTGACCTGCAC
TATCACCTTTCGCAGCACGGGGTGTTTTCTGAGAAGGAGATGCGGTTTTACGCCACAGAA
ATCATCCTGGGGCTGGAACACATGCACAATCGGTTTGTTGTTTACAGAGACTTGAAGCCC
GCCAATATCCTCCTGGATGAGCACGGACATGTGAGGATATCAGACCTTGGTCTTGCCTGC
GATTTTTCCAAAAAGAAGCCGCACGCGAGCGTGGGCACCCACGGGTACATGGCGCCCGAA
GTTCTGCAGAAGGGGACCGCCTACGACAGCAGTGCCGACTGGTTCTCCCTGGGCTGTATG
CTTTTCAAACTTCTGAGAGGTCACAGCCCTTTCAGACAACATAAAACCAAAGATAAGCAT
GAGATAGACCGAATGACTCTCACCATGAACGTGGAACTTCCAGACGTCTTCTCCCCTGAG
CTCAAGTCCCTTCTGGAAGGCCTGCTTCAGCGAGATGTCAGTAAGCGCCTCGGCTGCCAT
GGAGGCAGCGCACAGGAGCTAAAAACGCACGACTTCTTCAGAGGCATCGACTGGCAGCAC
GTCTACCTGCAGAAGTACCCTCCACCCTTGATCCCTCCCCGAGGGGAAGTCAATGCAGCC
GACGCCTTTGACATCGGCTCATTTGATGAAGAGGATACCAAAGGCATCAAGCTTCTTGAT
TGCGACCAAGAACTCTACAAGAACTTCCCTCTGGTGATCTCTGAGCGCTGGCAGCAGGAA
GTGGCGGAAACAGTTTATGAAGCAGTAAATGCAGACACGGATAAAATCGAGGCCAGGAAG
AGAGCTAAAAATAAGCAGCTTGGCCACGAAGAAGATTACGCCCTGGGAAGAGACTGCATC
GTGCACGGGTACATGCTGAAGCTGGGGAACCCTTTCCTGACCCAGTGGCAGCGCCGCTAT
TTTTACCTCTTTCCGAACAGACTTGAGTGGAGAGGAGAAGGCGAGTCGCGACAAAGTTTA
CTGACAATGGAACAGATTGTGTCCGTGGAAGAAACTCAGATTAAAGACAAAAAGTGCATT
TTGTTGAGAATAAAAGGAGGGAAGCAGTTCGTTTTGCAGTGTGAGAGTGACCCAGAGTTT
GTGCAGTGGAAGAAAGAGCTGACGGAGACATTCATGGAGGCCCAGCGGCTGCTACGGCGA
GCCCCCAAGTTCCTCAACAAATCCCGCTCAGCCGTCGTGGAACTCTCAAAGCCTCCCCTC
TGCCATAGGAACAGCAACGGCCTCTGA
Enzyme 32 GenBank Gene ID M73216 Link Image
Enzyme 32 GeneCard ID ADRBK2 Link Image
Enzyme 32 GenAtlas ID Not Available
Enzyme 32 HGNC ID Not Available
Enzyme 32 Chromosome Location Chromosome:2
Enzyme 32 Locus 22q11|22q12.1
Enzyme 32 SNPs SNPJam Report Link Image
Enzyme 32 General References
  1. [PubMed Link Image]
Enzyme 32 Metabolite References Not Available
Enzyme 33 [top]
Enzyme 33 ID 167
Enzyme 33 Name Dual specificity phosphatase DUPD1
Enzyme 33 Synonyms Not Available
Enzyme 33 Gene Name DUPD1
Enzyme 33 Protein Sequence >Dual specificity phosphatase DUPD1
MTSGESKTGLKNVYPSAKKLLPKVEEGEAEDYCTPGAFELERLFWKGSPQYTHVNEVWPK
LYIGDETTALDRYGLQKAGFTHVLNAAHGRWNVDTGPDYYRDMAIEYHGVEADDLPSFDL
SVFFYPAAAFIDAALRYDHNKILVHCVMGRSRSATLVLAYLMIHRNMTLVDAIQQVAKNR
CVLPNRGFLKQLRELDRQLVQQRRQAQQGEDAEKCEQEP
Enzyme 33 Number of Residues 219
Enzyme 33 Molecular Weight 24984.1
Enzyme 33 Theoretical pI 6.40
Enzyme 33 GO Classification
Function
Process
Component
Enzyme 33 General Function Signal transduction mechanisms
Enzyme 33 Specific Function Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Enzyme 33 Pathways Not Available
Enzyme 33 Reactions Not Available
Enzyme 33 Pfam Domain Function
Enzyme 33 Signals
  • None
Enzyme 33 Transmembrane Regions
  • None
Enzyme 33 Essentiality Not Available
Enzyme 33 GenBank ID Protein Not Available
Enzyme 33 UniProtKB/Swiss-Prot ID P0C591 Link Image
Enzyme 33 UniProtKB/Swiss-Prot Entry Name DUPD1_BOVIN Link Image
Enzyme 33 PDB ID Not Available
Enzyme 33 Cellular Location Not Available
Enzyme 33 Gene Sequence Not Available
Enzyme 33 GenBank Gene ID BF074326 Link Image
Enzyme 33 GeneCard ID DUPD1 Link Image
Enzyme 33 GenAtlas ID Not Available
Enzyme 33 HGNC ID Not Available
Enzyme 33 Chromosome Location Chromosome:1
Enzyme 33 Locus 10q22.2
Enzyme 33 SNPs SNPJam Report Link Image
Enzyme 33 General References
  1. [PubMed Link Image]
Enzyme 33 Metabolite References Not Available
Enzyme 34 [top]
Enzyme 34 ID 168
Enzyme 34 Name Cell division control protein 2 homolog
Enzyme 34 Synonyms
  1. p34 protein kinase
  2. Cyclin-dependent kinase 1
  3. CDK1
Enzyme 34 Gene Name CDC2
Enzyme 34 Protein Sequence >Cell division control protein 2 homolog
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKST
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDSQIKKM
Enzyme 34 Number of Residues 297
Enzyme 34 Molecular Weight 34025.1
Enzyme 34 Theoretical pI 8.77
Enzyme 34 GO Classification
Function
Process
Component
Enzyme 34 General Function Involved in ATP binding
Enzyme 34 Specific Function Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II
Enzyme 34 Pathways Not Available
Enzyme 34 Reactions Not Available
Enzyme 34 Pfam Domain Function
Enzyme 34 Signals
  • None
Enzyme 34 Transmembrane Regions
  • None
Enzyme 34 Essentiality Not Available
Enzyme 34 GenBank ID Protein 498173 Link Image
Enzyme 34 UniProtKB/Swiss-Prot ID P48734 Link Image
Enzyme 34 UniProtKB/Swiss-Prot Entry Name CDC2_BOVIN Link Image
Enzyme 34 PDB ID Not Available
Enzyme 34 Cellular Location Not Available
Enzyme 34 Gene Sequence >894 bp
ATGGAAGACTATACCAAAATAGAGAAAATTGGAGAAGGTACCTATGGAGTTGTGTATAAG
GGTAGACACAAAACTACAGGCCAAGTGGTAGCCATGAAGAAAATCAGACTAGAAAGTGAA
GAGGAAGGGGTTCCTAGTACTGCAATTCGGGAAATATCTCTATTAAAAGAGCTTCGTCAT
CCAAATATAGTCAGTCTTCAAGATGTGCTTATGCAGGATTCCAGGTTGTATCTCATCTTT
GAATTCCTTTCCATGGATCTCAAGAAATACTTGGATTCTATCCCTCCTGGTCAGTTCATG
GATTCTTCACTTGTTAAGAGTTATTTGTACCAAATCCTACAAGGGATTGTGTTTTGTCAC
TCTAGAAGAGTTCTCCACAGGGACTTAAAACCTCAAAATCTATTGATTGATGATAAAGGA
ACAATTAAGTTGGCAGATTTTGGCCTTGCCAGAGCTTTTGGAATTCCTATTAGAGTATAT
ACACATGAGGTAGTGACACTCTGGTATAGATCTCCAGAAGTATTGCTGGGGTCAGCTGGC
TACTCAACTCCAGTGGACATTTGGAGTATAGGTACCATATTTGCTGAATTAGCAACGAAG
AAACCACTTTTTCATGGGGATTCAGAAATTGATCAACTCTTCAGAATTTTCAGAGCTTTG
GGCACTCCCAATAATGAAGTGTGGCCAGAAGTGGAATCTTTACAGGACTATAAGAGTACA
TTTCCCAAGTGGAAACCAGGAAGCTTAGCATCCCATGTCAAAAACTTGGATGAAAATGGC
TTGGATCTGCTCTCGAAAATGTTAATCTATGATCCTGCCAAACGAATTTCTGGCAAAATG
GCACTGAATCATCCGTACTTTAATGATTTGGACAGTCAAATTAAGAAGATGTAG
Enzyme 34 GenBank Gene ID L26547 Link Image
Enzyme 34 GeneCard ID CDC2 Link Image
Enzyme 34 GenAtlas ID Not Available
Enzyme 34 HGNC ID Not Available
Enzyme 34 Chromosome Location Chromosome:1
Enzyme 34 Locus 10q21.1
Enzyme 34 SNPs SNPJam Report Link Image
Enzyme 34 General References
  1. [PubMed Link Image]
Enzyme 34 Metabolite References Not Available
Enzyme 35 [top]
Enzyme 35 ID 169
Enzyme 35 Name Folylpolyglutamate synthase, mitochondrial
Enzyme 35 Synonyms
  1. Folylpoly-gamma-glutamate synthetase
  2. FPGS
  3. Tetrahydrofolate synthase
  4. Tetrahydrofolylpolyglutamate synthase
Enzyme 35 Gene Name FPGS
Enzyme 35 Protein Sequence >Folylpolyglutamate synthase, mitochondrial
MSRARCHALFLAAVSPRGATTRVAVRRGLSAWPVLQEPDMEYQDAVRTLNTLQTNANYLE
MVKRKRGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRSYGL
KTGFFSSPHLVQVRERIRINGQPISSELFTKHFWRLYHRLEETKDDSSCVSMPGYFRFLT
LMAFHVFLQEKVDLAVLEVGIGGAYDCTNIIRKPVVCGITSLGIDHTGLLGDTMEKIAWQ
KGGIFKSGVPAFTVLQPDEPLAVLRDRAQQISCPLYLCPPLQALEEGGPPLTLGLEGEHQ
RSNAALALQVARCWLQQKGYQDAGELKASRPSLPGQLPLAPVFQPTPRMQQGLRHTEWPG
RTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALHRCERPDSGSEVRVLLFNSTGDRDSA
ALLKLLQPCQFDYAIFCPNLAEMASTDNADQQNFTVTLDQVLLRCLAHQQHWSRLHEEQV
SPDPWSTPGQEQDGPASLLLAPHPPHTHSASSLVFSCISHALQWITQGRDPLFQPPSPPR
GLLAHPVADSGATVLQEAADIHVLVTGSLHLVGGVLKLLEPSLSQ
Enzyme 35 Number of Residues 585
Enzyme 35 Molecular Weight 64899.8
Enzyme 35 Theoretical pI 7.73
Enzyme 35 GO Classification
Function
Process
Component
Enzyme 35 General Function Coenzyme transport and metabolism
Enzyme 35 Specific Function Conversion of folates to polyglutamate derivatives. This allows tissues to concentrate folate at higher levels than in plasma
Enzyme 35 Pathways
  • Cofactor biosynthesis
  • tetrahydrofolylpolyglutamate biosynthesis
Enzyme 35 Reactions Not Available
Enzyme 35 Pfam Domain Function
Enzyme 35 Signals
  • None
Enzyme 35 Transmembrane Regions
  • None
Enzyme 35 Essentiality Not Available
Enzyme 35 GenBank ID Protein 148877382 Link Image
Enzyme 35 UniProtKB/Swiss-Prot ID A6H751 Link Image
Enzyme 35 UniProtKB/Swiss-Prot Entry Name FOLC_BOVIN Link Image
Enzyme 35 PDB ID Not Available
Enzyme 35 Cellular Location Not Available
Enzyme 35 Gene Sequence >1758 bp
ATGTCTCGGGCACGCTGCCACGCTCTCTTCCTGGCAGCGGTTTCTCCGCGTGGTGCAACA
ACCAGGGTCGCAGTGCGGCGAGGGTTGAGCGCGTGGCCTGTGCTGCAGGAGCCAGACATG
GAGTATCAGGATGCCGTGCGTACACTCAACACCCTGCAGACCAATGCTAACTACTTGGAG
ATGGTGAAGCGTAAGCGGGGTGACCCCCAGACACAGCTGGAAGCCATGAAGCTGTACTTG
GCACGGAGTGGGCTGCAGGTGGAGGACTTGGACCAGCTGAACATTATCCACATCACTGGA
ACCAAGGGGAAGGGCTCCACGTGTGCCTTCACTGAACGTATCCTCCGAAGCTATGGCCTG
AAGACGGGGTTCTTTAGCTCTCCCCACCTGGTGCAGGTGCGTGAGCGGATCCGCATCAAT
GGGCAGCCCATAAGCTCCGAGCTCTTCACCAAGCACTTCTGGCGCCTCTACCACCGGCTG
GAGGAGACCAAGGACGACAGCAGCTGTGTCTCCATGCCCGGCTACTTCCGCTTCCTCACG
CTCATGGCCTTCCACGTCTTCCTCCAAGAGAAGGTAGACCTGGCAGTGTTGGAAGTAGGC
ATTGGCGGGGCTTACGACTGCACCAACATCATCAGGAAGCCTGTGGTGTGTGGGATCACC
TCTCTTGGCATCGACCACACTGGCCTTCTGGGGGACACGATGGAGAAGATCGCATGGCAG
AAAGGGGGCATTTTTAAGAGTGGCGTCCCTGCCTTCACCGTGCTCCAGCCTGACGAGCCG
CTGGCGGTGCTAAGGGACAGGGCTCAGCAGATCTCATGTCCCCTCTACCTGTGCCCACCA
CTACAAGCCCTGGAGGAAGGGGGGCCACCACTGACCCTGGGCCTGGAGGGAGAGCACCAG
CGGTCCAATGCTGCCCTGGCCTTGCAGGTGGCCCGCTGCTGGCTGCAGCAGAAAGGTTAC
CAGGATGCTGGGGAGCTGAAGGCATCCAGGCCCAGCCTCCCGGGGCAGCTGCCCCTGGCA
CCTGTGTTCCAGCCCACGCCCCGCATGCAGCAGGGGCTTCGGCACACGGAATGGCCAGGT
CGGACGCAGTTGCTGCGGCGCGGGCCTCTTACCTGGTACCTGGACGGCGCGCACACCACC
AGCAGCATGCAAGCCTGTGTGCGCTGGTTCCGCCAGGCGCTGCACCGCTGCGAGAGGCCG
GACAGCGGTTCCGAGGTGCGCGTCTTGCTCTTCAACTCCACTGGGGACCGGGATTCCGCG
GCCCTGCTGAAGCTGCTGCAGCCCTGCCAGTTTGACTATGCCATTTTCTGCCCTAACCTG
GCAGAGATGGCATCAACAGACAATGCAGACCAACAGAACTTCACAGTGACACTGGACCAG
GTGCTGCTCCGCTGCCTCGCCCACCAACAGCACTGGAGTCGCCTGCATGAGGAGCAGGTC
AGCCCGGACCCCTGGAGCACCCCCGGCCAGGAGCAGGATGGGCCCGCATCTCTGCTGCTG
GCGCCTCACCCACCCCACACCCACAGTGCCAGCTCCCTCGTCTTCAGCTGCATCTCCCAT
GCCTTGCAGTGGATCACCCAAGGCCGGGACCCTCTCTTTCAGCCGCCCAGTCCCCCACGG
GGCCTCCTCGCCCACCCTGTGGCAGACAGTGGGGCCACGGTACTCCAAGAGGCTGCTGAC
ATTCACGTGCTGGTCACAGGCAGCCTGCACCTGGTGGGCGGTGTCCTGAAGCTGCTGGAG
CCCTCCCTGTCCCAGTAG
Enzyme 35 GenBank Gene ID BC146114 Link Image
Enzyme 35 GeneCard ID FPGS Link Image
Enzyme 35 GenAtlas ID Not Available
Enzyme 35 HGNC ID Not Available
Enzyme 35 Chromosome Location Chromosome:9
Enzyme 35 Locus 9q34.1
Enzyme 35 SNPs SNPJam Report Link Image
Enzyme 35 General References Not Available
Enzyme 35 Metabolite References Not Available
Enzyme 36 [top]
Enzyme 36 ID 170
Enzyme 36 Name Dynamin-2
Enzyme 36 Synonyms Not Available
Enzyme 36 Gene Name DNM2
Enzyme 36 Protein Sequence >Dynamin-2
MGNRGMEELIPLVNKLQDAFSSIGQSCHLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLILQLIFSKTEYAEFLHCKSRKFTDFEEVRQEIEAETDRVTGTNKGISPVPI
NLRIYSPHVLNLTLIDLPGITKVPVGDQPQDIEYQIKDMILQFISRESSLILAVTPANMD
LANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
DIEGKKDIRTALAAERKFFLSHPAYRHIADRMGTPHLQKTLNQQLTNHIRESLPALRSKL
QSQLLSLEKEVEEYKNFRPDDPTRKTKALLQMVQQFGVDFEKRIEGSGDQVDTLELSGGA
RINRIFHERFPFELVKMEFDEKDLRREISYAIKNIHGVRTGLFTPDLAFEAIVKKQVVKL
KEPCLKCVDLVIQELINTVRQCTSKLSSYPRLREETERIVTTYIREREGRTKDQILLLID
IEQSYINTNHEDFIGFANAQQRSTQLNKKRAVPNQVIRRGWLTINNISLMKGGSKEYWFV
LTAESLSWYKDEEEKEKKYMLPLDNLKIRDVEKGFMSNKHVFAIFNTEQRNVYKDLRQIE
LACDSQEDVDSWKASFLRAGVYPEKDQAENEDGAQENTFSMDPQLERQVETIRNLVDSYV
AIINKSIRDLMPKTIMHLMINNTKAFIHYELLAYLYSSADQSSLMEESADQAQRRDDMLR
MYHALKEALNIIGDISTSTVSTPVPPPVDDTWIQNTSSHSPTPQRRPVSSVHPPGRPPAV
RGPTPGPPLIPVPVGPASFSAPPIPSRPGPHPGVFANNDPFSAPPQIPSRPARIPPGIPP
GVPSRRPPAAPSRPTIIRPAEPSLLD
Enzyme 36 Number of Residues 866
Enzyme 36 Molecular Weight 97835.0
Enzyme 36 Theoretical pI 7.69
Enzyme 36 GO Classification
Function
Process
Component
Enzyme 36 General Function Involved in GTP binding
Enzyme 36 Specific Function Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis
Enzyme 36 Pathways Not Available
Enzyme 36 Reactions Not Available
Enzyme 36 Pfam Domain Function
Enzyme 36 Signals
  • None
Enzyme 36 Transmembrane Regions
  • None
Enzyme 36 Essentiality Not Available
Enzyme 36 GenBank ID Protein 148877311 Link Image
Enzyme 36 UniProtKB/Swiss-Prot ID A6H7I5 Link Image
Enzyme 36 UniProtKB/Swiss-Prot Entry Name DYN2_BOVIN Link Image
Enzyme 36 PDB ID Not Available
Enzyme 36 Cellular Location Not Available
Enzyme 36 Gene Sequence >2601 bp
ATGGGCAACCGCGGGATGGAAGAGCTGATCCCGCTGGTCAACAAGCTGCAGGATGCCTTC
AGTTCCATCGGCCAGAGCTGCCACCTGGACCTGCCGCAGATCGCCGTGGTGGGCGGCCAG
AGCGCCGGCAAGAGCTCTGTGCTCGAGAACTTCGTGGGCCGGGACTTCCTTCCCCGAGGT
TCAGGAATCGTCACTCGGCGGCCTCTCATCCTGCAGCTCATCTTCTCAAAAACAGAATAT
GCCGAGTTTTTGCACTGCAAGTCCAGAAAGTTTACAGACTTTGAGGAAGTCCGACAGGAG
ATCGAAGCGGAGACTGACAGGGTCACGGGGACCAACAAGGGCATCTCCCCAGTGCCCATT
AACCTGCGGATCTACTCGCCACACGTGTTGAACCTGACCCTCATCGACCTCCCAGGCATC
ACAAAGGTGCCTGTGGGGGACCAGCCCCAGGATATCGAGTACCAGATCAAGGACATGATC
TTGCAGTTCATCAGCCGGGAAAGCAGCCTCATCCTTGCTGTCACCCCCGCCAACATGGAC
CTGGCCAACTCAGACGCCCTAAAGCTGGCCAAGGAGGTCGATCCTCAAGGCCTGCGGACC
ATCGGCGTCATCACCAAACTCGACCTGATGGACGAAGGCACGGATGCCAGGGATGTCCTG
GAGAACAAGCTACTCCCCTTGAGGAGAGGCTACATTGGAGTGGTCAACCGCAGCCAGAAG
GATATTGAGGGCAAGAAGGACATCCGCACAGCACTGGCGGCCGAGAGGAAGTTTTTCCTC
TCCCACCCAGCCTACCGGCACATAGCTGACCGCATGGGCACCCCGCACCTGCAGAAGACT
CTGAATCAGCAACTGACCAACCACATCCGGGAATCACTGCCGGCCCTGCGCAGCAAGCTG
CAGAGCCAGCTGCTATCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTCCGGCCCGAT
GACCCCACACGCAAGACCAAAGCTCTCCTGCAGATGGTCCAGCAGTTTGGGGTGGACTTT
GAGAAGAGGATTGAGGGCTCTGGAGACCAGGTGGACACACTGGAGCTCTCTGGGGGCGCC
CGGATCAATCGCATCTTCCACGAGCGATTTCCCTTCGAGCTGGTGAAGATGGAGTTTGAT
GAGAAAGACTTAAGACGGGAGATCAGCTACGCCATTAAAAATATCCACGGAGTCAGGACC
GGGCTCTTCACCCCGGACTTGGCATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTG
AAAGAGCCCTGTCTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATACAGTTAGG
CAGTGTACCAGTAAGCTCAGCTCCTACCCGCGGTTGCGAGAGGAAACGGAACGCATCGTC
ACCACTTACATCCGGGAACGGGAGGGGAGGACCAAGGACCAGATTCTTCTTCTGATTGAC
ATTGAGCAGTCCTACATCAACACCAACCACGAGGACTTCATTGGATTTGCCAACGCCCAG
CAGAGGAGCACACAGCTGAATAAGAAGAGAGCCGTCCCCAACCAGGTGATCCGCAGGGGC
TGGCTAACCATCAACAATATCAGCCTGATGAAGGGAGGCTCCAAGGAGTACTGGTTCGTG
CTGACGGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGAAGTACATG
CTGCCTCTGGACAACCTCAAAATCCGTGACGTGGAGAAGGGCTTCATGTCCAACAAGCAC
GTCTTCGCCATCTTCAACACAGAGCAGAGGAATGTCTACAAGGACCTGCGGCAGATCGAG
CTGGCCTGTGACTCCCAGGAGGACGTGGACAGCTGGAAGGCCTCATTCCTCCGAGCTGGG
GTCTATCCAGAGAAGGACCAGGCAGAAAATGAGGATGGAGCCCAGGAGAACACCTTCTCC
ATGGACCCGCAGTTGGAGCGGCAGGTGGAGACCATTCGCAACCTGGTGGACTCGTACGTG
GCCATAATCAACAAGTCCATCCGTGACCTCATGCCAAAGACCATCATGCACCTCATGATC
AACAACACGAAGGCCTTCATCCACTATGAGCTGCTGGCCTACCTGTACTCGTCGGCGGAC
CAGAGCAGCCTCATGGAAGAGTCGGCTGACCAGGCCCAGCGGCGGGATGACATGCTTCGC
ATGTACCACGCGCTCAAGGAGGCACTCAACATCATTGGGGACATCAGCACCAGCACTGTG
TCCACTCCCGTGCCCCCACCCGTTGACGACACCTGGATCCAGAACACCAGCAGCCACAGC
CCCACTCCGCAGCGCCGGCCCGTATCCAGCGTGCACCCCCCAGGCCGGCCCCCAGCAGTG
AGGGGTCCCACCCCAGGGCCACCCCTGATTCCTGTGCCGGTGGGGCCAGCTTCCTTCTCA
GCGCCCCCGATCCCATCCCGGCCCGGCCCCCACCCCGGCGTGTTTGCCAACAACGACCCC
TTCTCGGCCCCACCTCAGATCCCATCTCGGCCGGCTCGGATTCCACCCGGCATTCCCCCT
GGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCC
GAGCCATCTCTGCTCGACTAG
Enzyme 36 GenBank Gene ID BC146259 Link Image
Enzyme 36 GeneCard ID DNM2 Link Image
Enzyme 36 GenAtlas ID Not Available
Enzyme 36 HGNC ID Not Available
Enzyme 36 Chromosome Location Chromosome:1
Enzyme 36 Locus 19p13.2
Enzyme 36 SNPs SNPJam Report Link Image
Enzyme 36 General References Not Available
Enzyme 36 Metabolite References Not Available
Enzyme 37 [top]
Enzyme 37 ID 171
Enzyme 37 Name Interferon-inducible GTPase 5
Enzyme 37 Synonyms
  1. Immunity-related GTPase cinema 1
Enzyme 37 Gene Name IRGC
Enzyme 37 Protein Sequence >Interferon-inducible GTPase 5
MATSKLPAVSGEEETTILMAKEELEALRTAFESGDIPQAASRLRELLASSDCTRLEVGVT
GESGAGKSSLINALRGLGAEDPDAALTGVVETTIEPSPYPHPQFPDVTLWDLPGAGSPGC
SADKYLKQVDFGRYDFFLLVSPRRCGAVETRLASEILRQGKKFYFVRTKVDEDLAATRMQ
RPSGFSEGAVLHEIREHCVERLRGAGVHDPRVFLVSNLSPARYDFPLLMSTWERDLPAHR
RHAGLLSLPDISLEALQEKKDMLQEQVLKTALVSGVIQALPVPGLAAAYDDALLIRSLRG
YHRSFGLDDDSLAKLAEQVGKQAGDLRSVIRSPLANEVSPETVLRLYSQSSDGAMRVARA
FEKGIPVFGTLVAGGISFGTVYTMLQGCLNEMAEDAQRVRIKALEEEEDTQPDVSLEAAG
DNGVEKRGSGEGSMEEAPLSTRRKLGLLLKYILDSWKKRDLAEDK
Enzyme 37 Number of Residues 465
Enzyme 37 Molecular Weight 50697.0
Enzyme 37 Theoretical pI 4.97
Enzyme 37 GO Classification
Function
Process
Component
Enzyme 37 General Function Involved in GTP binding
Enzyme 37 Specific Function GTP + H(2)O = GDP + phosphate
Enzyme 37 Pathways Not Available
Enzyme 37 Reactions Not Available
Enzyme 37 Pfam Domain Function
Enzyme 37 Signals
  • None
Enzyme 37 Transmembrane Regions
  • None
Enzyme 37 Essentiality Not Available
Enzyme 37 GenBank ID Protein 81673717 Link Image
Enzyme 37 UniProtKB/Swiss-Prot ID Q32KW9 Link Image
Enzyme 37 UniProtKB/Swiss-Prot Entry Name IIGP5_BOVIN Link Image
Enzyme 37 PDB ID Not Available
Enzyme 37 Cellular Location Not Available
Enzyme 37 Gene Sequence >1398 bp
ATGGCTACTTCGAAGTTGCCAGCGGTGTCCGGGGAGGAGGAGACCACCATCCTCATGGCC
AAGGAAGAGCTGGAGGCCCTGCGCACTGCCTTCGAGTCGGGAGACATCCCGCAGGCCGCT
TCCCGCCTCCGGGAGCTGCTGGCCTCCTCGGACTGCACCCGGCTGGAGGTGGGCGTCACA
GGCGAATCGGGGGCCGGCAAGTCGTCCCTCATCAACGCCCTTCGCGGCCTGGGCGCCGAG
GACCCCGACGCGGCCCTCACCGGCGTCGTGGAGACCACAATAGAGCCCTCGCCCTACCCG
CACCCGCAGTTTCCAGACGTGACCCTGTGGGACCTGCCAGGGGCCGGCTCTCCCGGCTGC
TCGGCGGACAAGTACCTGAAGCAGGTGGACTTCGGCCGCTACGATTTCTTCCTACTTGTC
TCACCCCGCCGCTGCGGCGCGGTGGAGACCCGCCTGGCCTCCGAGATCCTGCGCCAGGGC
AAGAAGTTCTATTTCGTGCGCACCAAGGTGGACGAGGACCTGGCGGCCACGCGCATGCAG
CGGCCCTCGGGCTTCAGCGAGGGGGCGGTCCTGCACGAGATCCGCGAGCACTGCGTCGAG
CGGCTGCGCGGGGCCGGCGTCCACGACCCGCGCGTCTTCCTTGTGTCCAACCTCTCGCCC
GCGCGCTACGACTTCCCGCTGCTCATGTCCACCTGGGAGCGCGATCTGCCCGCGCATCGG
CGCCACGCCGGCCTGCTGTCGCTGCCGGACATCTCGCTGGAGGCCCTGCAGGAGAAGAAG
GACATGCTCCAGGAGCAGGTGCTCAAGACGGCCCTGGTGTCCGGCGTCATCCAGGCCCTG
CCCGTGCCCGGGCTGGCGGCCGCCTACGACGACGCGCTGCTCATCCGCTCGCTGCGCGGC
TACCACCGCAGCTTCGGCCTGGACGACGACTCGCTGGCCAAGCTGGCCGAGCAGGTGGGC
AAACAGGCGGGGGACCTGCGCTCCGTCATCCGCTCCCCGCTGGCCAACGAGGTCTCCCCT
GAGACGGTCCTGCGGCTCTACTCCCAGTCGTCCGACGGTGCCATGAGGGTGGCCCGGGCC
TTTGAGAAGGGTATCCCCGTGTTCGGGACGCTGGTGGCGGGGGGCATCAGCTTCGGCACC
GTCTACACCATGCTCCAGGGCTGCCTGAACGAGATGGCCGAGGATGCCCAGCGCGTCCGC
ATCAAGGCTCTGGAGGAAGAGGAGGACACTCAGCCCGATGTCAGCCTGGAGGCGGCTGGT
GACAACGGAGTGGAGAAACGGGGATCCGGGGAGGGGAGCATGGAGGAAGCCCCCCTCTCG
ACCCGCCGGAAGCTTGGCCTCCTCCTTAAGTACATTCTGGACAGCTGGAAGAAGCGAGAC
TTGGCCGAAGACAAATGA
Enzyme 37 GenBank Gene ID BC109879 Link Image
Enzyme 37 GeneCard ID IRGC Link Image
Enzyme 37 GenAtlas ID Not Available
Enzyme 37 HGNC ID Not Available
Enzyme 37 Chromosome Location Chromosome:1
Enzyme 37 Locus 19q13.31
Enzyme 37 SNPs SNPJam Report Link Image
Enzyme 37 General References Not Available
Enzyme 37 Metabolite References Not Available
Enzyme 38 [top]
Enzyme 38 ID 172
Enzyme 38 Name ITK protein
Enzyme 38 Synonyms Not Available
Enzyme 38 Gene Name ITK
Enzyme 38 Protein Sequence >ITK protein
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKTSLAYFEDRHGKKRTLKGSIELSRI
KCVEIVKSDIIIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPKY
HPNFWLDGRWRCCAQMEKLAVGCAQYDPTKNASKKPLPPTPEDNRRSLRELEETVVIALY
DYQTNDPQELMLQRNEEYYLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWY
NKNISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIVSENNPCIKHYHIKETND
NPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCSWRQKAPVTAGLRYGKWVIDP
SELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQ
LYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLEEACVIH
RDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSD
VWSFGVLMWEVFSEGKIPYENRSNSEVVEDITTGFRLYKPRLASQHIYQIMNHCWKEKPE
DRPPFSRLLSQLAEIAELGL
Enzyme 38 Number of Residues 620
Enzyme 38 Molecular Weight 72068.8
Enzyme 38 Theoretical pI 7.34
Enzyme 38 GO Classification
Function
Process
Component
Enzyme 38 General Function Involved in ATP binding
Enzyme 38 Specific Function ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Enzyme 38 Pathways Not Available
Enzyme 38 Reactions Not Available
Enzyme 38 Pfam Domain Function
Enzyme 38 Signals
  • None
Enzyme 38 Transmembrane Regions
  • None
Enzyme 38 Essentiality Not Available
Enzyme 38 GenBank ID Protein 157279248 Link Image
Enzyme 38 UniProtKB/Swiss-Prot ID A7Z039 Link Image
Enzyme 38 UniProtKB/Swiss-Prot Entry Name A7Z039_BOVIN Link Image
Enzyme 38 PDB ID 1SNX Link Image
Enzyme 38 PDB File Show
Enzyme 38 3D Structure
Enzyme 38 Cellular Location Not Available
Enzyme 38 Gene Sequence >1863 bp
ATGAACAACTTTATCCTCCTGGAAGAGCAGCTCATCAAGAAATCCCAACAAAAGAGAAGA
ACTTCTCCTTCAAACTTTAAAGTCCGATTCTTTGTTTTAACCAAAACCAGCCTGGCATAC
TTTGAAGATCGTCATGGGAAAAAGCGCACTTTGAAGGGCTCCATCGAACTCTCCCGAATC
AAATGTGTCGAGATTGTGAAAAGTGACATTATCATCCCATGTCACTATAAATATCCATTT
CAGGTTGTTCACGACAACTACCTCCTGTATGTGTTTGCTCCAGACCGGGAGAGCCGGCAG
CGCTGGGTGCTGGCCCTCAAAGAAGAAACCAGGAATAACAACAGTTTGGTGCCCAAGTAT
CACCCTAATTTCTGGTTGGATGGGAGATGGCGGTGCTGTGCTCAGATGGAGAAGCTTGCA
GTGGGCTGTGCCCAGTACGATCCCACCAAAAATGCTTCAAAGAAGCCTCTTCCTCCTACT
CCTGAAGACAATAGGCGGTCACTTCGGGAACTTGAAGAAACTGTGGTCATTGCCCTGTAT
GACTACCAAACGAATGATCCACAGGAACTCATGCTACAGCGCAATGAGGAGTACTACCTG
CTCGACAGCTCTGAGATTCACTGGTGGAGGGTTCAGGACAGGAACGGGCATGAAGGATAT
GTTCCAAGCAGTTATCTGGTGGAAAAGTCTCCAAATAACCTGGAAACCTATGAGTGGTAC
AATAAGAACATCAGCCGAGACAAAGCTGAAAAACTTCTTTTGGACACAGGCAAAGAAGGA
GCCTTTATGGTGCGAGATTCCAGGACTCCAGGGACATACACCGTGTCCGTTTTCACCAAG
GCCATCGTAAGTGAGAACAACCCCTGTATAAAGCATTATCACATCAAAGAAACAAATGAC
AACCCCAAGCGATATTACGTGGCTGAAAAGTATGTGTTTGATTCCATCCCTCTCCTCATC
AATTATCACCAGCACAACGGAGGAGGCCTGGTCACTAGACTCCGGTATCCAGTTTGCTCC
TGGAGGCAGAAAGCCCCCGTCACCGCAGGGCTGAGATACGGGAAATGGGTGATTGATCCC
TCGGAGCTCACTTTTGTGCAGGAGATTGGCAGTGGGCAGTTTGGGTTGGTGCACCTTGGC
TACTGGCTCAACAAGGACAAGGTGGCCATCAAAACCATACAAGAAGGGGCTATGTCAGAA
GAGGACTTCATTGAGGAGGCTGAAGTCATGATGAAACTCTCTCACCCCAAACTAGTCCAG
CTCTATGGAGTATGCCTGGAACAGGCCCCCATCTGCCTGGTGTTTGAATTCATGGAACAC
GGCTGCCTGTCAGATTACCTGCGTAGCCAGAGGGGGCTCTTTGCTGCGGAGACCCTGCTG
GGCATGTGTCTGGACGTATGTGAGGGCATGGCCTACCTGGAAGAGGCATGTGTCATCCAC
AGAGACTTGGCTGCCCGGAATTGTTTAGTTGGGGAAAACCAAGTTATCAAGGTGTCCGAC
TTTGGGATGACAAGGTTCGTCCTTGATGACCAATACACCAGTTCCACAGGCACCAAATTC
CCAGTGAAGTGGGCATCTCCGGAAGTCTTCTCCTTCAGTCGCTACAGCAGCAAGTCAGAT
GTGTGGTCATTTGGTGTGCTGATGTGGGAAGTCTTCAGTGAAGGCAAAATCCCATACGAA
AACCGAAGCAACTCAGAGGTGGTAGAAGACATCACCACTGGATTTCGGTTATACAAGCCC
CGACTGGCCTCCCAGCATATCTACCAGATCATGAATCATTGCTGGAAAGAGAAACCAGAA
GACCGGCCACCTTTCTCCAGACTCTTGAGTCAACTGGCTGAAATTGCAGAATTGGGGCTT
TAA
Enzyme 38 GenBank Gene ID BC153237 Link Image
Enzyme 38 GeneCard ID ITK Link Image
Enzyme 38 GenAtlas ID Not Available
Enzyme 38 HGNC ID Not Available
Enzyme 38 Chromosome Location Chromosome:5
Enzyme 38 Locus 5q31-q32
Enzyme 38 SNPs SNPJam Report Link Image
Enzyme 38 General References Not Available
Enzyme 38 Metabolite References Not Available
Enzyme 39 [top]
Enzyme 39 ID 173
Enzyme 39 Name Glucose-6-phosphatase 3
Enzyme 39 Synonyms
  1. G-6-Pase 3
  2. G6Pase 3
Enzyme 39 Gene Name G6PC3
Enzyme 39 Protein Sequence >Glucose-6-phosphatase 3
MESTLGAGIAMAEALQNQLPWLENVWLWVTFLGDPKSLFLFYFPAAYYASRRVGIAVLWI
SLITEWLNLVFKWFLFGDRPFWWVHESGYYSQAPAQVHQFPSSCETGPGSPSGHCMITGA
ALWPIMTAVSSQMATRAHSRWVRVIPSLAYCTFLLAVGLSRVFLLAHFPHQVLAGLITGA
VLGWLMTPQVPMERELSFYGLTSLALLLGASLIYWTLFTLGLDLSWSINLASKWCERPEW
VHLDSRPFASLSRDSGAALGLGIALHSPCYAQVRRAHLGYGQKLVCLVLAMGLLGPLNWL
GYPPQISLFYIFNFLKYTLWPCLVLALVPWLVHMFSAQEAPPIRSS
Enzyme 39 Number of Residues 346
Enzyme 39 Molecular Weight 38742.1
Enzyme 39 Theoretical pI 8.28
Enzyme 39 GO Classification
Function
Process
Component
Enzyme 39 General Function Involved in glucose-6-phosphatase activity
Enzyme 39 Specific Function Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function
Enzyme 39 Pathways
  • Carbohydrate biosynthesis
  • gluconeogenesis
Enzyme 39 Reactions Not Available
Enzyme 39 Pfam Domain Function
Enzyme 39 Signals
  • None
Enzyme 39 Transmembrane Regions
  • 25-45 55-75 109-129 141-162 168-186 198-218 255-273 284-304 308-328
Enzyme 39 Essentiality Not Available
Enzyme 39 GenBank ID Protein 30984013 Link Image
Enzyme 39 UniProtKB/Swiss-Prot ID Q148G2 Link Image
Enzyme 39 UniProtKB/Swiss-Prot Entry Name G6PC3_BOVIN Link Image
Enzyme 39 PDB ID Not Available
Enzyme 39 Cellular Location Not Available
Enzyme 39 Gene Sequence >1041 bp
ATGGAGTCCACGCTGGGCGCGGGCATCGCGATGGCCGAGGCGCTGCAGAACCAGCTGCCC
TGGTTGGAGAACGTGTGGCTCTGGGTCACCTTTCTGGGGGACCCCAAGAGCCTCTTTCTG
TTCTACTTCCCCGCGGCCTACTATGCGTCTCGCCGGGTGGGCATTGCGGTGCTCTGGATC
AGCCTCATCACCGAGTGGCTCAACCTCGTCTTCAAGTGGTTTCTGTTTGGAGACAGGCCC
TTTTGGTGGGTCCATGAGTCTGGGTACTACAGCCAAGCTCCAGCCCAGGTTCACCAATTC
CCCTCTTCTTGTGAAACTGGCCCAGGCAGCCCTTCTGGACACTGTATGATCACAGGAGCA
GCCCTCTGGCCCATAATGACAGCCGTCTCTTCCCAGATGGCCACTCGGGCCCACAGCCGC
TGGGTGAGGGTGATTCCTAGCTTGGCTTATTGCACCTTCCTGCTGGCGGTCGGCTTATCT
CGGGTCTTCCTCTTAGCACATTTCCCTCACCAGGTGTTGGCTGGCTTAATAACTGGTGCT
GTCCTGGGCTGGCTGATGACCCCTCAGGTGCCCATGGAGCGGGAGCTAAGTTTCTATGGA
TTGACCTCACTGGCCCTCTTGCTGGGTGCCAGCCTCATCTACTGGACCCTCTTTACACTG
GGCCTGGATCTTTCTTGGTCCATCAACCTAGCCTCTAAGTGGTGTGAGCGGCCTGGGTGG
GTGCACTTGGACAGCCGGCCTTTTGCCTCCCTGAGCCGTGACTCAGGGGCCGCCCTGGGT
CTGGGCATCGCTCTGCACTCTCCCTGCTATGCCCAGGTACGGCGGGCACACCTGGGATAT
GGCCAGAAACTAGTCTGTCTTGTGCTGGCCATGGGGCTGCTGGGCCCCCTGAACTGGCTG
GGCTACCCCCCTCAGATCAGCCTTTTCTACATCTTCAATTTCCTCAAGTACACCCTCTGG
CCATGCCTGGTCCTGGCCCTCGTACCCTGGCTGGTGCACATGTTCAGTGCCCAGGAAGCA
CCACCCATCCGCTCTTCCTGA
Enzyme 39 GenBank Gene ID AY279358 Link Image
Enzyme 39 GeneCard ID G6PC3 Link Image
Enzyme 39 GenAtlas ID Not Available
Enzyme 39 HGNC ID Not Available
Enzyme 39 Chromosome Location Chromosome:1
Enzyme 39 Locus 17q21.31
Enzyme 39 SNPs SNPJam Report Link Image
Enzyme 39 General References Not Available
Enzyme 39 Metabolite References Not Available
Enzyme 40 [top]
Enzyme 40 ID 174
Enzyme 40 Name S-adenosylmethionine synthetase
Enzyme 40 Synonyms Not Available
Enzyme 40 Gene Name MAT2A
Enzyme 40 Protein Sequence >S-adenosylmethionine synthetase
MNGQLNGFHDAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
KTGMILLAGEITSRAAVDYQKVVRETIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
Enzyme 40 Number of Residues 395
Enzyme 40 Molecular Weight 43690.4
Enzyme 40 Theoretical pI 6.45
Enzyme 40 GO Classification
Function
Process
Component
Enzyme 40 General Function Coenzyme transport and metabolism
Enzyme 40 Specific Function Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Enzyme 40 Pathways
  • Amino-acid biosynthesis
  • S-adenosyl-L-methionine biosynthesis
  • S-adenosyl-L-methionine from L-methionine:step 1/1
Enzyme 40 Reactions Not Available
Enzyme 40 Pfam Domain Function
Enzyme 40 Signals
  • None
Enzyme 40 Transmembrane Regions
  • None
Enzyme 40 Essentiality Not Available
Enzyme 40 GenBank ID Protein 152941174 Link Image
Enzyme 40 UniProtKB/Swiss-Prot ID A7E3T7 Link Image
Enzyme 40 UniProtKB/Swiss-Prot Entry Name A7E3T7_BOVIN Link Image
Enzyme 40 PDB ID Not Available
Enzyme 40 Cellular Location Not Available
Enzyme 40 Gene Sequence >1188 bp
ATGAACGGGCAGCTCAACGGCTTCCACGACGCGTTCATCGAGGAGGGCACGTTCCTCTTT
ACCTCCGAGTCCGTGGGGGAAGGCCACCCAGATAAGATCTGTGACCAGATCAGTGATGCT
GTCCTTGATGCCCACCTTCAGCAGGACCCTGATGCCAAAGTGGCTTGTGAAACTGTTGCT
AAGACTGGAATGATCCTTCTTGCTGGGGAAATTACATCCAGAGCTGCTGTTGACTACCAG
AAAGTGGTTCGTGAAACCATTAAACACATTGGATATGACGATTCTTCCAAAGGGTTTGAC
TACAAGACATGTAATGTGCTAGTGGCCTTGGAGCAACAGTCACCAGATATTGCCCAAGGT
GTTCATCTTGACCGAAACGAGGAAGACATTGGTGCAGGAGACCAGGGTTTGATGTTTGGT
TATGCCACTGATGAAACTGAGGAATGTATGCCTTTAACCATTGTCTTAGCACACAAGCTC
AATGCCAAACTGGCTGAACTGCGCCGGAATGGCACTTTGCCTTGGTTACGCCCTGATTCT
AAAACTCAAGTGACTGTGCAGTATATGCAGGATCGAGGTGCCGTACTTCCCATCAGAGTC
CACACAATTGTTATATCTGTTCAGCATGATGAAGAAGTTTGTCTTGATGAGATGAGAGAT
GCTCTGAAGGAGAAAGTCATCAAAGCTGTTGTACCTGCAAAGTACCTTGATGAGGACACA
ATCTATCATCTACAGCCAAGTGGCAGATTTGTTATTGGTGGGCCTCAGGGTGATGCTGGT
TTGACTGGCCGGAAAATCATTGTGGACACTTACGGTGGTTGGGGAGCTCATGGAGGAGGT
GCCTTTTCAGGAAAGGATTATACCAAGGTGGACCGTTCAGCTGCTTATGCTGCTCGTTGG
GTGGCAAAATCCCTTGTTAAAGGAGGTCTGTGCAGAAGGGTTCTTGTTCAGGTCTCTTAT
GCTATTGGAGTATCTCATCCATTGTCTATCTCCATTTTCCATTATGGCACCTCTCAGAAG
AGTGAGAGAGAGCTATTAGAGATTGTGAAGAAGAATTTTGACCTCCGCCCTGGGGTCATT
GTCAGGGATCTGGATCTGAAGAAGCCAATTTATCAGAGGACTGCAGCCTATGGCCACTTT
GGTAGGGACAGCTTCCCATGGGAAGTGCCCAAAAAGCTTAAATATTGA
Enzyme 40 GenBank Gene ID BT030708 Link Image
Enzyme 40 GeneCard ID MAT2A Link Image
Enzyme 40 GenAtlas ID Not Available
Enzyme 40 HGNC ID Not Available
Enzyme 40 Chromosome Location Chromosome:2
Enzyme 40 Locus 2p11.2
Enzyme 40 SNPs SNPJam Report Link Image
Enzyme 40 General References
  1. [PubMed Link Image]
Enzyme 40 Metabolite References Not Available
Enzyme 41 [top]
Enzyme 41 ID 175
Enzyme 41 Name ATP-citrate synthase
Enzyme 41 Synonyms
  1. ATP-citrate (pro-S-)-lyase
  2. Citrate cleavage enzyme
Enzyme 41 Gene Name ACLY
Enzyme 41 Protein Sequence >ATP-citrate synthase
MSAKAISEQTGKELLYKYICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQSLVVKPD
QLIKRRGKLGLIGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHTQEEEFY
VCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEI
LASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPP
PFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNE
LANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRA
IRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALG
HRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRTDEVAPAKKAKPAMLQGKSA
TLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILI
PVFKNMADAMKKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLI
KKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNEL
NNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTAGVKMIVVLGEIGGTEEYKICRG
VTEGRITKPVVCWCIGTCAAMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSF
DELGEIIQSVYEDLVARGVIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQ
ELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNT
IICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLI
MGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIG
VAFVDMLRHCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDD
ISYVLPEHMSM
Enzyme 41 Number of Residues 1091
Enzyme 41 Molecular Weight 119788.1
Enzyme 41 Theoretical pI 7.25
Enzyme 41 GO Classification
Function
Process
Component
Enzyme 41 General Function Energy production and conversion
Enzyme 41 Specific Function ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine
Enzyme 41 Pathways Not Available
Enzyme 41 Reactions Not Available
Enzyme 41 Pfam Domain Function
Enzyme 41 Signals
  • None
Enzyme 41 Transmembrane Regions
  • None
Enzyme 41 Essentiality Not Available
Enzyme 41 GenBank ID Protein 79158721 Link Image
Enzyme 41 UniProtKB/Swiss-Prot ID Q32PF2 Link Image
Enzyme 41 UniProtKB/Swiss-Prot Entry Name ACLY_BOVIN Link Image
Enzyme 41 PDB ID Not Available
Enzyme 41 Cellular Location Not Available
Enzyme 41 Gene Sequence >3276 bp
ATGTCGGCCAAGGCGATTTCTGAGCAGACAGGCAAAGAGCTCCTCTACAAGTACATCTGC
ACCACCTCGGCCATCCAGAACCGCTTCAAGTATGCCCGGGTCACCCCTGACACAGACTGG
GCCCGCCTGTTGCAGGACCACCCGTGGCTGCTCAGCCAGAGCTTGGTGGTCAAGCCAGAC
CAGCTGATCAAACGGCGTGGAAAGCTGGGCCTAATTGGGGTCAACCTCACTCTGGATGGA
GTCAAGTCCTGGCTGAAGCCACGCCTGGGACAGGAAGCTACAGTTGGCAAGGCCACAGGC
TTCCTCAAGAACTTCCTGATCGAACCCTTCGTCCCCCACACTCAGGAGGAAGAGTTCTAC
GTCTGCATCTATGCTACCCGAGAAGGGGACTATGTCCTGTTCCACCACGAGGGTGGGGTG
GACGTGGGCGACGTGGATGCTAAAGCCCAGAAACTACTTGTCGGCGTCGATGAGAAGCTG
AATCCTGAGGACATCAAGAAACACCTGCTGGTCCACGCCCCCGAAGACAAGAAAGAAATT
CTGGCCAGCTTTATCTCCGGCCTCTTCAATTTCTATGAGGATCTGTACTTCACCTACCTC
GAGATCAACCCCCTTGTCGTGACCAAAGATGGCGTCTACGTCCTTGACTTGGCCGCCAAG
GTGGATGCCACTGCCGACTACATCTGCAAAGTGAAGTGGGGTGACATAGAGTTCCCACCC
CCCTTCGGACGGGAGGCTTACCCAGAGGAAGCCTACATCGCAGATCTGGACGCCAAAAGT
GGGGCAAGCTTGAAGCTGACTTTACTGAATCCCAAGGGGAGAATCTGGACCATGGTGGCC
GGAGGGGGTGCCTCTGTCGTGTACAGTGACACCATCTGCGACCTGGGGGGTGTCAACGAG
CTGGCAAACTACGGGGAGTACTCGGGCGCCCCCAGCGAGCAGCAGACCTATGACTACGCC
AAGACGATCCTCTCCCTTATGACCCGCGAGAAGCACCCAGATGGCAAGATCCTCATCATC
GGAGGCAGCATCGCAAACTTCACCAACGTGGCTGCCACATTCAAGGGCATCGTGAGAGCA
ATTCGAGATTACCAGGGTCCCCTGAAGGAGCACGAGGTCACGATCTTTGTCCGAAGAGGT
GGCCCCAACTATCAGGAGGGCTTACGGGTCATGGGAGAAGTCGGGAAGACCACTGGGATC
CCCATCCATGTCTTCGGCACTGAGACTCACATGACGGCCATCGTGGGCATGGCCCTGGGC
CATCGGCCCATCCCCAATCAGCCGCCCACAGCGGCCCACACCGCAAACTTCCTCCTCAAC
GCCAGCGGGAGTACTTCAACTCCAGCCCCCAGCAGGACGGCATCTTTTTCTGAGTCCAGA
ACTGATGAGGTGGCCCCTGCCAAGAAGGCCAAGCCTGCCATGCTCCAAGGAAAGAGCGCC
ACCCTCTTCAGCCGCCACACCAAGGCCATCGTGTGGGGCATGCAGACCCGGGCTGTGCAG
GGCATGCTGGACTTCGACTACGTCTGCTCCCGCGACGAGCCCTCAGTGGCTGCCATGGTC
TACCCGTTCACTGGGGACCACAAACAGAAGTTTTACTGGGGTCACAAGGAGATCCTGATC
CCCGTCTTTAAGAACATGGCTGATGCCATGAAGAAGCACCCAGAGGTAGACGTGCTAATC
AACTTTGCCTCCCTGCGCTCAGCCTACGACAGCACCATGGAGACCATGAATTACGCTCAG
ATCCGGACCATCGCCATCATAGCCGAAGGCATCCCTGAGGCGCTCACGAGGAAGCTGATC
AAGAAGGCAGACCAGAAGGGAGTGACCATCATTGGACCTGCCACCGTTGGTGGCATCAAG
CCCGGGTGCTTTAAGATCGGGAACACCGGCGGGATGCTGGACAACATCCTGGCCTCTAAG
CTGTACCGCCCAGGCAGTGTGGCCTATGTCTCGCGTTCGGGTGGCATGTCCAACGAGCTC
AACAATATCATCTCTCGAACCACAGATGGCGTCTACGAGGGCGTGGCCATTGGTGGGGAC
AGGTACCCCGGCTCAACGTTTATGGATCACGTGTTACGTTATCAGGACACTGCAGGAGTC
AAAATGATTGTGGTTCTTGGAGAGATAGGGGGCACAGAGGAGTATAAGATCTGCCGGGGC
GTCACGGAGGGCCGCATCACCAAGCCCGTGGTCTGCTGGTGCATCGGGACCTGTGCGGCC
ATGTTCTCCTCCGAGGTCCAGTTCGGCCACGCTGGAGCTTGTGCCAACCAGGCTTCTGAA
ACCGCAGTTGCCAAGAACCAGGCCTTGAAGGAGGCTGGAGTGTTTGTGCCCCGGAGCTTC
GATGAGCTTGGAGAAATCATCCAGTCCGTGTACGAGGATCTCGTGGCCAGAGGAGTCATT
GTGCCTGCTCAGGAGGTTCCGCCCCCCACAGTACCCATGGACTACTCTTGGGCCCGGGAA
TTGGGCTTGATCCGCAAACCTGCCTCGTTCATGACCAGCATCTGTGACGAGCGAGGACAG
GAGCTCATCTACGCGGGCATGCCCATCACTGAGGTCTTCAAGGAGGAGATGGGCATTGGC
GGGGTCCTCGGCCTCCTCTGGTTCCAGAAAAGGTTGCCCAAATACTCCTGCCAGTTCATT
GAGATGTGCCTGATGGTGACGGCTGATCACGGGCCTGCCGTCTCTGGGGCTCATAACACC
ATCATCTGCGCTCGAGCCGGCAAGGACCTCGTCTCCAGCCTCACCTCGGGACTGCTTACC
ATTGGCGACCGGTTTGGGGGTGCCCTGGATGCAGCAGCCAAGATGTTCAGCAAGGCCTTT
GACAGTGGTATCATCCCCATGGAGTTTGTGAACAAGATGAAGAAGGAAGGAAAGCTTATC
ATGGGCATTGGTCACCGAGTGAAGTCGATCAACAACCCAGACATGCGCGTGCAGATTCTC
AAAGATTATGTCAGACAACACTTCCCTGCCACCCCACTGCTCGACTACGCACTGGAAGTA
GAGAAGATTACCACTTCCAAGAAACCAAACCTTATCCTGAATGTGGACGGTTTAATCGGA
GTTGCATTTGTAGACATGCTTAGACACTGCGGGTCCTTCACTCGGGAGGAAGCTGATGAA
TATATTGACATTGGAGCCCTCAACGGCATCTTTGTGCTGGGAAGGAGCATGGGCTTCATT
GGACACTATCTTGATCAGAAGAGGCTGAAGCAGGGGCTCTACCGTCACCCATGGGATGAT
ATTTCATATGTTCTTCCGGAACACATGAGCATGTAA
Enzyme 41 GenBank Gene ID BC108138 Link Image
Enzyme 41 GeneCard ID ACLY Link Image
Enzyme 41 GenAtlas ID Not Available
Enzyme 41 HGNC ID Not Available
Enzyme 41 Chromosome Location Chromosome:1
Enzyme 41 Locus 17q12-q21
Enzyme 41 SNPs SNPJam Report Link Image
Enzyme 41 General References Not Available
Enzyme 41 Metabolite References Not Available
Enzyme 42 [top]
Enzyme 42 ID 176
Enzyme 42 Name Fructose-1,6-bisphosphatase 1
Enzyme 42 Synonyms
  1. FBPase 1
  2. D-fructose-1,6-bisphosphate 1-phosphohydrolase 1
Enzyme 42 Gene Name FBP1
Enzyme 42 Protein Sequence >Fructose-1,6-bisphosphatase 1
MTDQAAFDTNIVTVTRFVMEEGRKARGTGEMTQLLNSLCTAVKAISTAVRKAGIAHLYGI
AGTTNVTGDQVKKLDVLSNDLVVNVLKSSFATCVLVSEEDEHAIIVEPEKRGKYVVCFDP
LDGSSNIDCLVSIGTIFGIYKKISKDDPSEKDALQPGRNLVAAGYALYGSATMLVLAMAN
GVNCFMLDPAIGEFILVDRDVKIKKKGSIYSLNEGYAKDFDPALTEYVQRKKFPPDNSAP
YGARYVGSMVADVHRTLVYGGIFMYPANKKSPSGKLRLLYECNPMAYVIEKAGGMATTGK
ETVLDIVPTDIHQKSPIILGSPEDVTEFLEIYKKHAAK
Enzyme 42 Number of Residues 338
Enzyme 42 Molecular Weight 36728.0
Enzyme 42 Theoretical pI 7.01
Enzyme 42 GO Classification
Function
Process
Component
Enzyme 42 General Function Carbohydrate transport and metabolism
Enzyme 42 Specific Function D-fructose 1,6-bisphosphate + H(2)O = D- fructose 6-phosphate + phosphate
Enzyme 42 Pathways
  • Carbohydrate biosynthesis
  • gluconeogenesis
Enzyme 42 Reactions Not Available
Enzyme 42 Pfam Domain Function
Enzyme 42 Signals
  • None
Enzyme 42 Transmembrane Regions
  • None
Enzyme 42 Essentiality Not Available
Enzyme 42 GenBank ID Protein 74354240 Link Image
Enzyme 42 UniProtKB/Swiss-Prot ID Q3SZB7 Link Image
Enzyme 42 UniProtKB/Swiss-Prot Entry Name F16P1_BOVIN Link Image
Enzyme 42 PDB ID 1NV7 Link Image
Enzyme 42 PDB File Show
Enzyme 42 3D Structure
Enzyme 42 Cellular Location Not Available
Enzyme 42 Gene Sequence >1017 bp
ATGACGGACCAGGCAGCCTTCGACACCAATATCGTCACCGTGACCCGCTTCGTCATGGAA
GAGGGCAGGAAGGCCCGTGGCACGGGCGAGATGACCCAACTGCTCAACTCGCTTTGCACC
GCGGTCAAAGCCATCTCCACGGCCGTGCGCAAGGCGGGCATCGCGCACCTCTATGGAATT
GCTGGCACTACCAATGTGACGGGAGATCAAGTGAAGAAGCTGGATGTCCTCTCCAATGAC
CTGGTTGTTAATGTGTTAAAGTCATCTTTTGCTACCTGTGTTCTTGTGTCAGAAGAAGAT
GAACATGCCATAATAGTAGAACCTGAGAAAAGGGGTAAATATGTGGTCTGTTTTGATCCC
CTTGATGGATCATCCAACATCGACTGCCTTGTGTCCATTGGAACCATCTTTGGCATCTAC
AAAAAGATTTCGAAAGATGACCCTTCTGAGAAGGACGCTCTGCAGCCAGGCCGGAACCTG
GTGGCTGCTGGCTATGCGCTCTATGGCAGTGCCACTATGTTGGTCCTGGCCATGGCGAAT
GGAGTCAACTGCTTCATGCTGGACCCGGCCATTGGAGAGTTCATTTTGGTGGACAGGGAT
GTGAAGATCAAAAAGAAAGGGAGCATCTATAGCCTCAATGAAGGCTATGCGAAGGACTTT
GATCCTGCCCTCACCGAGTATGTCCAGAGGAAGAAGTTCCCCCCAGACAACTCAGCCCCC
TATGGCGCCAGGTACGTGGGCTCCATGGTAGCCGATGTACACCGCACCCTAGTCTATGGA
GGGATCTTTATGTATCCAGCTAACAAGAAAAGCCCCAGTGGAAAGCTGAGACTACTGTAT
GAATGTAACCCCATGGCCTATGTCATAGAGAAGGCAGGAGGAATGGCTACCACCGGGAAG
GAAACTGTGCTGGACATTGTTCCCACTGACATCCATCAGAAGTCGCCCATCATCTTGGGG
TCTCCTGAAGATGTGACTGAGTTCCTGGAGATATACAAGAAGCATGCTGCCAAATGA
Enzyme 42 GenBank Gene ID BC102974 Link Image
Enzyme 42 GeneCard ID FBP1 Link Image
Enzyme 42 GenAtlas ID Not Available
Enzyme 42 HGNC ID Not Available
Enzyme 42 Chromosome Location Chromosome:9
Enzyme 42 Locus 9q22.3
Enzyme 42 SNPs SNPJam Report Link Image
Enzyme 42 General References Not Available
Enzyme 42 Metabolite References Not Available
Enzyme 43 [top]
Enzyme 43 ID 177
Enzyme 43 Name Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Enzyme 43 Synonyms
  1. E-NPP 2
  2. Extracellular lysophospholipase D
  3. LysoPLD
  4. Autotaxin
Enzyme 43 Gene Name ENPP2
Enzyme 43 Protein Sequence >Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
MARRRSCQLHQVISLFTFAVGVNICLGVTANRIKRAEGWGEGPPTVLSDSPSINISGSCK
GRCFELQEAGPPDCRCDNLCKSYSSCCLDFDELCLKTAGGWECTKDRCGEVRNEDHACHC
SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKTPECPAGFVRPPLIIFSVDGFRASYMK
KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA
HFNLRGREKFNHRWWGGQPLWITATKQGVIAGTFFWPVVIPHERRILTILQWLTLPDHER
PSVYAFYSEQPDFSGHKYGPFGPEMTNPLRDIDKTVGQLMDGLKQLKLHRCVNVIFVGDH
GMEDVTCDRTEFLSNYLTNVDDIILVPGTLGRIRPKFNNHAKYDPKVIIANLTCKKPDQH
FKPYLKQHLPKRLHYANNRRIEDVHLLVERRWHVARKPLEVYKKPSGKCFFQGDHGFDNK
VNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF
RPTVPEEVTRPNYPGVMYLQSDFDLGCTCDDKAEPKNKLDELNKHLHIKESTEAETRKFR
GSKNEIKENVNGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT
VSKQADVSDIPAHLTNCVRPDVRVSPSFSQSCLAYKNDKQMSYGFLFPPYLSSSPEAKYD
AFLVTNMVPMYPAFKRIWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTQDKIKQ
YVEGSSVPVPTHYYSILTSCLDFTQPADRCDGPLSVSAFVLPHRPDNDESCNSSEDESKW
VEELLKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLQTYESEI
Enzyme 43 Number of Residues 888
Enzyme 43 Molecular Weight 101715.9
Enzyme 43 Theoretical pI 7.56
Enzyme 43 GO Classification
Function
Process
Component
Enzyme 43 General Function Involved in alkylglycerophosphoethanolamine phosphodies
Enzyme 43 Specific Function Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility- related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor
Enzyme 43 Pathways Not Available
Enzyme 43 Reactions Not Available
Enzyme 43 Pfam Domain Function
Enzyme 43 Signals
  • 1-27
Enzyme 43 Transmembrane Regions
  • None
Enzyme 43 Essentiality Not Available
Enzyme 43 GenBank ID Protein 119224048 Link Image
Enzyme 43 UniProtKB/Swiss-Prot ID A1A4K5 Link Image
Enzyme 43 UniProtKB/Swiss-Prot Entry Name ENPP2_BOVIN Link Image
Enzyme 43 PDB ID Not Available
Enzyme 43 Cellular Location Not Available
Enzyme 43 Gene Sequence >2667 bp
ATGGCCAGGAGACGCTCCTGCCAGCTCCATCAGGTGATATCTCTGTTCACTTTTGCCGTC
GGTGTCAATATCTGCTTAGGAGTCACAGCAAATCGAATTAAGAGGGCAGAAGGATGGGGT
GAAGGCCCTCCTACAGTGTTATCAGACTCCCCCTCGATCAACATCTCTGGGTCTTGCAAG
GGCAGATGCTTTGAACTTCAAGAGGCTGGACCCCCTGATTGTCGATGTGACAACTTGTGT
AAGAGCTATAGCAGCTGCTGCCTTGACTTTGATGAGCTCTGCTTGAAGACAGCTGGTGGC
TGGGAGTGTACCAAGGACAGATGCGGAGAAGTAAGAAATGAAGACCATGCTTGTCACTGC
TCGGAGGACTGCTTGGCCCGGGGAGACTGTTGCACTAATTACCAAGTGGTTTGCAAAGGA
GAGTCTCACTGGGTGGATGATGACTGTGAGGAAATAAAGACCCCAGAATGCCCTGCAGGG
TTCGTTCGCCCTCCGCTGATCATCTTCTCTGTGGACGGTTTCCGCGCATCGTACATGAAG
AAAGGCAGCAAGGTCATGCCTAACATCGAAAAGCTGAGGTCTTGTGGCACTCACTCCCCC
TACATGAGGCCTGTGTACCCGACGAAAACTTTCCCTAACTTATACACTCTGGCCACTGGG
CTGTATCCAGAATCACATGGAATTGTTGGCAATTCCATGTATGATCCTGTTTTTGATGCA
CATTTCAACCTTCGAGGGCGAGAGAAATTTAACCATAGGTGGTGGGGAGGTCAACCGCTA
TGGATTACAGCCACGAAGCAAGGGGTGATCGCTGGGACATTCTTCTGGCCTGTGGTGATC
CCCCACGAGCGGAGAATACTGACCATCCTGCAGTGGCTGACCCTGCCGGACCACGAAAGG
CCTTCAGTCTATGCCTTCTATTCCGAACAACCTGATTTCTCTGGACACAAGTATGGCCCC
TTTGGCCCTGAGATGACGAATCCTCTGAGGGACATTGACAAAACCGTGGGGCAGTTAATG
GATGGATTGAAGCAACTGAAGCTGCACCGCTGCGTGAATGTCATCTTCGTTGGAGACCAT
GGAATGGAAGATGTCACATGTGATAGAACAGAATTCTTGAGCAATTACCTGACTAATGTG
GATGATATTATTTTAGTGCCAGGAACTCTAGGAAGAATTCGACCCAAATTCAACAATCAT
GCTAAATATGACCCGAAAGTCATTATTGCTAATCTCACGTGTAAAAAACCAGACCAGCAC
TTTAAGCCTTACTTGAAACAGCACCTTCCCAAACGTTTGCACTACGCCAACAACAGAAGG
ATCGAAGACGTCCATTTACTGGTGGAGCGCAGATGGCACGTCGCAAGGAAACCTTTGGAG
GTTTATAAGAAACCATCAGGAAAATGTTTTTTCCAGGGAGACCACGGATTTGATAACAAG
GTCAACAGTATGCAGACTGTTTTTGTAGGTTATGGCCCAACATTTAAGTACAAGACCAAA
GTGCCTCCATTTGAAAACATTGAACTTTACAACGTTATGTGCGATCTCCTGGGATTGAAG
CCAGCTCCAAATAACGGGACCCACGGGAGTCTGAACCATCTCCTGCGTACCAACACCTTC
AGACCGACTGTGCCAGAGGAAGTCACCAGACCCAATTACCCAGGGGTTATGTACCTTCAG
TCCGATTTTGACCTGGGCTGTACCTGTGATGATAAGGCAGAGCCAAAGAACAAATTGGAT
GAACTCAACAAACACCTTCATATAAAAGAGTCCACAGAAGCTGAAACCAGGAAATTCAGA
GGCAGCAAAAATGAAATCAAGGAAAACGTTAATGGAAATTTTGAACCTAGAAAAGAGAGA
CATCTCCTCTATGGACGGCCTGCCGTGCTCTATCGGACTAGATATGATATCTTATATCAC
ACTGACTTTGAAAGCGGTTATAGTGAAATATTTCTAATGCCACTCTGGACATCATACACT
GTTTCCAAACAGGCTGACGTCTCTGACATCCCTGCACACCTGACCAACTGTGTCCGGCCC
GACGTCCGCGTTTCTCCGAGTTTCAGTCAGAGCTGTTTGGCCTACAAAAATGATAAACAG
ATGTCCTATGGATTCCTCTTTCCTCCCTATCTGAGCTCGTCCCCAGAAGCTAAATATGAT
GCATTCCTTGTAACCAATATGGTTCCAATGTATCCTGCTTTTAAACGCATCTGGAATTAT
TTCCAAAGGGTTCTGGTGAAGAAATATGCTTCAGAAAGAAATGGAGTTAATGTGATAAGT
GGACCAATCTTTGACTATGACTACGATGGCTTACACGACACACAAGACAAAATCAAACAG
TACGTGGAGGGCAGCTCCGTCCCCGTGCCCACCCACTACTACAGCATCCTCACCAGCTGC
CTGGACTTCACGCAGCCTGCCGACCGCTGCGACGGGCCGCTCTCCGTGTCCGCCTTCGTG
CTGCCCCACAGGCCCGACAACGACGAGAGCTGCAACAGCTCAGAGGACGAGTCGAAATGG
GTGGAAGAGCTTCTCAAGATGCACACAGCACGGGTGCGGGACATCGAGCATCTCACCAGC
CTGGACTTCTTCCGCAAGACCAGCCGCAGCTACCCAGAAATTCTGACCCTAAAGACGTAC
CTGCAGACGTATGAGAGCGAGATCTAG
Enzyme 43 GenBank Gene ID BC126631 Link Image
Enzyme 43 GeneCard ID ENPP2 Link Image
Enzyme 43 GenAtlas ID Not Available
Enzyme 43 HGNC ID Not Available
Enzyme 43 Chromosome Location Chromosome:8
Enzyme 43 Locus 8q24.1
Enzyme 43 SNPs SNPJam Report Link Image
Enzyme 43 General References
  1. [PubMed Link Image]
Enzyme 43 Metabolite References Not Available
Enzyme 44 [top]
Enzyme 44 ID 178
Enzyme 44 Name G protein-coupled receptor kinase 5
Enzyme 44 Synonyms
  1. G protein-coupled receptor kinase GRK5
Enzyme 44 Gene Name GRK5
Enzyme 44 Protein Sequence >G protein-coupled receptor kinase 5
MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHINQCEDLRRTIDRDYCSLCDKQ
PVGRLLFRQFCETRPGLESYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFITQ
VGRDLVSQTEEKLLQKPCKELFSACVQSVHDYLRGEPFHEYLDSMYFDRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK
VNSRFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE
DLHHENIVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ
RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC
KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI
EQFSTVKGVNLDHTDDDFYSKFSTGSVPIPWQSEMIETECFKELNVFGPHGTLSPDLNRS
HPPEPPKKGLLQRLFKRQHQNNSKSSPNSKTSFNHHINSNHVSSNSTGSS
Enzyme 44 Number of Residues 590
Enzyme 44 Molecular Weight 67888.2
Enzyme 44 Theoretical pI 8.32
Enzyme 44 GO Classification
Function
Process
Component
Enzyme 44 General Function Involved in ATP binding
Enzyme 44 Specific Function Specifically phosphorylates the activated forms of G protein-coupled receptors
Enzyme 44 Pathways Not Available
Enzyme 44 Reactions Not Available
Enzyme 44 Pfam Domain Function
Enzyme 44 Signals
  • None
Enzyme 44 Transmembrane Regions
  • None
Enzyme 44 Essentiality Not Available
Enzyme 44 GenBank ID Protein 437106 Link Image
Enzyme 44 UniProtKB/Swiss-Prot ID P43249 Link Image
Enzyme 44 UniProtKB/Swiss-Prot Entry Name GRK5_BOVIN Link Image
Enzyme 44 PDB ID Not Available
Enzyme 44 Cellular Location Not Available
Enzyme 44 Gene Sequence >1773 bp
ATGGAGCTGGAAAACATCGTGGCCAACACGGTCTTGCTGAAAGCCAGGGAAGGAGGCGGA
GGAAAGCGCAAAGGGAAAAGCAAGAAGTGGAAGGAAATCCTGAAGTTCCCTCACATAAAC
CAGTGTGAAGACCTCCGAAGAACCATAGACCGAGATTACTGCAGTTTATGTGACAAACAG
CCAGTCGGGAGGCTGCTTTTCCGGCAGTTCTGCGAAACCAGACCTGGGCTGGAGTCCTAC
ATTCAGTTCCTGGACTCGGTGGCAGAATATGAAGTTACTCCAGATGAAAAACTGGGAGAA
AAAGGGAAGGAAATTATGACCAAGTACCTCACCCCAAAGTCCCCAGTTTTCATCACCCAA
GTTGGACGGGACCTGGTCTCCCAGACGGAGGAGAAGCTCCTTCAGAAACCCTGCAAAGAA
CTCTTCTCGGCCTGCGTGCAGTCTGTCCACGACTACCTGAGGGGAGAACCCTTCCACGAG
TACCTGGACAGCATGTATTTTGATCGCTTTCTCCAGTGGAAGTGGTTGGAAAGGCAACCG
GTAACCAAAAACACTTTCAGGCAGTACCGAGTACTAGGAAAAGGGGGCTTTGGGGAGGTC
TGTGCCTGCCAGGTTCGGGCCACGGGTAAAATGTACGCCTGCAAACGCTTGGAGAAGAAG
AGGATCAAAAAGAGGAAAGGGGAGTCCATGGCCCTGAATGAGAAGCAGATTCTGGAGAAG
GTCAACAGTCGGTTTGTGGTCAACCTGGCCTACGCCTACGAGACCAAGGATGCCCTGTGT
TTGGTCCTGACCATCATGAACGGCGGGGACCTGAAGTTCCACATTTACAACATGGGGAAC
CCCGGCTTCGAGGAGGAGCGCGCCCTGTTCTACGCGGCAGAGATCCTGTGCGGCCTGGAG
GACCTCCACCATGAGAACATTGTCTACAGAGATTTGAAACCTGAAAATATCCTGTTAGAC
GATTACGGCCACATTAGAATTTCGGACCTGGGCCTGGCCGTGAAGATCCCCGAGGGAGAC
CTGATTCGCGGCCGAGTGGGCACCGTTGGCTACATGGCTCCAGAGGTCCTGAACAACCAG
AGGTATGGCCTGAGCCCCGACTACTGGGGTCTGGGCTGCCTCATCTACGAGATGATCGAG
GGCCAGTCGCCCTTCCGCGGCCGCAAGGAGAAGGTGAAGCGGGAGGAGGTGGACCGCCGG
GTGTTGGAGACAGAGGAGGTGTACTCGCACAAGTTCTCCGAGGAGGCCAAGTCCATCTGC
AAAATGCTGCTCACCAAAGATGCAAAGCAGAGGCTGGGCTGCCAGGAGGAAGGGGCCGCG
GAGGTCAAGAGACACCCCTTCTTCAGGAACATGAATTTCAAGCGCTTAGAGGCCGGGATG
TTGGATCCCCCCTTTGTTCCAGATCCCCGGGCCGTGTACTGCAAGGACGTCTTGGACATC
GAGCAGTTCTCCACCGTGAAGGGCGTCAACCTGGACCACACGGACGACGACTTCTACTCC
AAGTTCTCCACGGGCTCTGTGCCCATCCCGTGGCAAAGCGAGATGATAGAAACAGAGTGC
TTTAAGGAGCTGAACGTGTTCGGACCCCACGGTACCCTCTCACCGGACCTGAACCGAAGC
CACCCTCCGGAACCGCCAAAGAAAGGGCTGCTCCAGAGGCTCTTCAAGCGTCAGCATCAA
AACAATTCCAAGAGTTCACCCAATTCCAAGACCAGTTTTAACCACCACATCAATTCAAAC
CACGTGAGTTCAAACTCCACCGGAAGCAGCTAG
Enzyme 44 GenBank Gene ID U01206 Link Image
Enzyme 44 GeneCard ID GRK5 Link Image
Enzyme 44 GenAtlas ID Not Available
Enzyme 44 HGNC ID Not Available
Enzyme 44 Chromosome Location Chromosome:1
Enzyme 44 Locus 10q24-qter
Enzyme 44 SNPs SNPJam Report Link Image
Enzyme 44 General References
  1. [PubMed Link Image]
Enzyme 44 Metabolite References Not Available
Enzyme 45 [top]
Enzyme 45 ID 179
Enzyme 45 Name YES1 protein
Enzyme 45 Synonyms Not Available
Enzyme 45 Gene Name YES1
Enzyme 45 Protein Sequence >YES1 protein
MGCIKSKENKSPSIKYRPENTPEPVSTGVGHYGGEHAVVAPTSSTKSTSANFSSLSMTPF
GGSSAVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIIN
NTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIF
LVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTE
HADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKV
AIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKE
GDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIE
DNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVL
EQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGEN
L
Enzyme 45 Number of Residues 541
Enzyme 45 Molecular Weight 60596.5
Enzyme 45 Theoretical pI 6.79
Enzyme 45 GO Classification
Function
Process
Component
Enzyme 45 General Function Involved in ATP binding
Enzyme 45 Specific Function ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Enzyme 45 Pathways Not Available
Enzyme 45 Reactions Not Available
Enzyme 45 Pfam Domain Function
Enzyme 45 Signals
  • None
Enzyme 45 Transmembrane Regions
  • None
Enzyme 45 Essentiality Not Available
Enzyme 45 GenBank ID Protein 154425902 Link Image
Enzyme 45 UniProtKB/Swiss-Prot ID A7MB57 Link Image
Enzyme 45 UniProtKB/Swiss-Prot Entry Name A7MB57_BOVIN Link Image
Enzyme 45 PDB ID Not Available
Enzyme 45 Cellular Location Not Available
Enzyme 45 Gene Sequence >1626 bp
ATGGGCTGCATTAAAAGTAAAGAGAACAAAAGTCCATCCATTAAATATAGACCAGAAAAC
ACGCCAGAGCCGGTCAGCACAGGAGTAGGCCATTATGGAGGAGAACACGCTGTGGTGGCA
CCAACATCCTCCACGAAGAGCACATCTGCCAATTTCAGCAGCCTCTCCATGACGCCATTC
GGAGGGTCCTCGGCGGTGACACCTTTTGGAGGAGCATCTTCCTCGTTTTCAGTGGTGCCA
AGTTCATATCCTGCTGGTTTAACAGGTGGTGTTACTATATTTGTGGCCTTATATGATTAT
GAAGCTAGAACTACAGAAGACCTTTCATTTAAGAAAGGTGAAAGATTTCAAATAATTAAC
AACACGGAAGGAGACTGGTGGGAGGCGAGATCAATCGCTACAGGAAAGAACGGCTACATC
CCAAGCAATTACGTAGCCCCGGCGGATTCCATTCAGGCTGAAGAATGGTATTTTGGCAAA
ATGGGGAGAAAAGATGCGGAAAGATTACTTCTGAATCCTGGGAATCAGCGAGGTATTTTC
TTAGTAAGAGAGAGTGAAACTACTAAAGGTGCTTACTCCCTCTCTATTCGGGACTGGGAT
GAGGTGAGGGGTGACAATGTGAAGCACTACAAAATTAGGAAACTTGACAATGGTGGATAC
TACATCACAACCAGAGCACAGTTTGACACTCTGCAGAAACTGGTAAAACACTACACAGAA
CATGCCGATGGTTTATGCCATAAGTTAACAACTGTGTGTCCAACTGTGAAACCCCAGACT
CAAGGTCTAGCAAAAGATGCTTGGGAAATCCCGCGAGAATCTTTGCGACTAGAGGTTAAA
CTAGGACAAGGATGTTTTGGTGAAGTTTGGATGGGAACGTGGAATGGAACCACAAAAGTA
GCGATCAAAACACTGAAGCCAGGTACAATGATGCCAGAAGCTTTTCTTCAAGAGGCTCAG
ATAATGAAAAAACTAAGACATGATAAACTTGTTCCACTATATGCTGTTGTTTCTGAAGAG
CCGATTTACATTGTCACTGAGTTTATGTCAAAAGGGAGCTTATTGGATTTCCTGAAGGAG
GGAGATGGAAAGTATCTGAAGCTCCCACAGCTGGTTGACATGGCTGCTCAGATTGCTGAT
GGTATGGCCTATATTGAAAGAATGAACTATATTCATCGAGATCTTCGGGCTGCTAATATT
CTCGTAGGCGAAAACCTTGTGTGCAAAATAGCAGATTTTGGCTTAGCAAGGTTAATTGAA
GACAATGAATATACGGCAAGACAAGGTGCAAAATTTCCAATCAAGTGGACAGCTCCTGAG
GCTGCACTGTATGGTCGATTTACAATCAAGTCTGATGTATGGTCATTTGGAATTCTACAG
ACAGAACTGGTAACAAAGGGCAGAGTGCCATATCCAGGTATGGTGAACCGCGAGGTGCTG
GAGCAGGTGGAGCGAGGGTACAGGATGCCATGCCCGCAGGGCTGCCCAGAGTCCCTCCAC
GAATTGATGAATCTGTGTTGGAAGAAGGACCCTGATGAGAGACCAACATTTGAGTATATC
CAGTCCTTCCTGGAAGACTATTTCACTGCTACAGAGCCACAGTACCAGCCAGGAGAAAAT
TTATAA
Enzyme 45 GenBank Gene ID BC151348 Link Image
Enzyme 45 GeneCard ID YES1 Link Image
Enzyme 45 GenAtlas ID Not Available
Enzyme 45 HGNC ID Not Available
Enzyme 45 Chromosome Location Chromosome:1
Enzyme 45 Locus 18p11.31-p11.21
Enzyme 45 SNPs SNPJam Report Link Image
Enzyme 45 General References Not Available
Enzyme 45 Metabolite References Not Available
Enzyme 46 [top]
Enzyme 46 ID 180
Enzyme 46 Name FGR protein
Enzyme 46 Synonyms Not Available
Enzyme 46 Gene Name FGR
Enzyme 46 Protein Sequence >FGR protein
MGCVFCKKLEPGAKEDGGLEGDFRNYGAADRYGPDPTQSRPASSFSHIPNYNSFSPQPAS
PAFLDAGTIRGISGIGVTMFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSS
GHTGYIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNSRGAFLIRESETTKGAYSL
SIRDWDQTRGDHVKHYKIRKLDTGGYYITTRAQFDTVQELVQHYLEVNDGLCHLLTAACT
TMKPQTLGLAKDAWEISRSSITLEHRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKA
FLAEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCHGSLLEFLKGPEGHVLKLPHLVDM
AAQVAEGMAYMERMNYIHRDLRAANILVGERLVCKIADFGLARLIEDDEYNPQQGTKFPI
KWTAPEAALFCRFTIKSDVWSFGILITELITKGRVPYPGMNNREVLEQVEHGYHMPCPPG
CPASLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDDT
Enzyme 46 Number of Residues 527
Enzyme 46 Molecular Weight 59331.7
Enzyme 46 Theoretical pI 5.37
Enzyme 46 GO Classification
Function
Process
Component
Enzyme 46 General Function Involved in ATP binding
Enzyme 46 Specific Function ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Enzyme 46 Pathways Not Available
Enzyme 46 Reactions Not Available
Enzyme 46 Pfam Domain Function
Enzyme 46 Signals
  • None
Enzyme 46 Transmembrane Regions
  • None
Enzyme 46 Essentiality Not Available
Enzyme 46 GenBank ID Protein 148744204 Link Image
Enzyme 46 UniProtKB/Swiss-Prot ID A5PKG9 Link Image
Enzyme 46 UniProtKB/Swiss-Prot Entry Name A5PKG9_BOVIN Link Image
Enzyme 46 PDB ID Not Available
Enzyme 46 Cellular Location Not Available
Enzyme 46 Gene Sequence >1584 bp
ATGGGCTGTGTGTTCTGCAAGAAGTTGGAGCCAGGGGCCAAGGAGGATGGTGGCCTAGAA
GGGGACTTCAGGAACTATGGGGCTGCAGACCGCTATGGCCCCGACCCTACTCAGAGCCGG
CCTGCATCTTCCTTTTCCCACATCCCCAACTACAACAGCTTCTCCCCTCAGCCCGCCAGC
CCCGCCTTCCTCGATGCGGGCACCATCCGGGGCATCTCAGGGATTGGGGTGACCATGTTC
ATCGCCCTTTATGACTATGAGGCCCGAACGGAGGACGATCTCACCTTCACCAAGGGCGAG
AAGTTCCACATCCTGAACAACACCGAGGGTGACTGGTGGGAGGCTCGGTCCCTCAGCTCC
GGACACACTGGCTACATTCCCAGCAACTACGTGGCCCCCGTGGACTCCATCCAGGCTGAA
GAGTGGTACTTCGGAAAGATCGGGAGGAAGGACGCTGAGAGGCAGCTGCTCTCCCCAGGG
AACTCCCGCGGGGCCTTTCTCATTAGAGAGAGCGAGACCACCAAAGGCGCCTACTCCCTG
TCCATCCGGGATTGGGACCAGACCAGAGGCGATCATGTGAAGCATTACAAGATCCGCAAA
CTGGACACCGGTGGCTACTACATCACCACGAGGGCCCAGTTTGACACTGTGCAGGAGCTG
GTGCAGCACTACCTTGAGGTGAACGATGGGCTGTGCCATCTGCTCACGGCGGCCTGCACC
ACCATGAAGCCGCAGACGCTGGGCCTGGCCAAGGATGCCTGGGAAATCAGCCGCAGCTCC
ATCACGCTGGAGCACCGACTGGGCACCGGCTGCTTCGGGGATGTGTGGCTGGGCACGTGG
AACGGCAGCACCAAGGTGGCGGTGAAGACGCTAAAGCCGGGCACCATGTCCCCGAAGGCC
TTCCTGGCAGAGGCGCAGATCATGAAGCTGCTGCGGCACGACAAGCTGGTGCAGCTGTAC
GCGGTGGTGTCAGAGGAGCCCATCTACATAGTGACCGAGTTCATGTGCCACGGTAGCCTG
CTGGAGTTCCTCAAGGGCCCGGAGGGTCATGTTTTGAAGCTGCCCCATCTGGTGGACATG
GCGGCACAGGTTGCTGAGGGCATGGCCTACATGGAGCGCATGAACTATATTCACCGTGAC
CTCCGGGCAGCCAACATCCTCGTCGGGGAGCGGCTGGTGTGCAAGATCGCTGACTTCGGG
CTGGCCCGACTCATCGAAGATGACGAGTACAACCCCCAGCAAGGGACCAAGTTCCCCATC
AAGTGGACAGCCCCTGAGGCTGCCCTCTTTTGCAGATTCACTATCAAGTCAGATGTGTGG
TCCTTTGGGATCCTGATCACTGAACTCATCACCAAGGGCCGAGTCCCCTACCCAGGCATG
AATAACCGCGAAGTGTTGGAACAAGTGGAGCATGGCTACCACATGCCGTGCCCCCCAGGC
TGCCCAGCATCCCTGTACGAGGTCATGGAACAAACCTGGCGTCTGGACCCAGAGGAGAGA
CCCACCTTCGAGTACCTGCAGTCCTTCCTTGAGGACTATTTCACCTCCACAGAACCCCAG
TACCAGCCTGGGGATGACACATAG
Enzyme 46 GenBank Gene ID BC142483 Link Image
Enzyme 46 GeneCard ID FGR Link Image
Enzyme 46 GenAtlas ID Not Available
Enzyme 46 HGNC ID Not Available
Enzyme 46 Chromosome Location Chromosome:1
Enzyme 46 Locus 1p36.2-p36.1
Enzyme 46 SNPs SNPJam Report Link Image
Enzyme 46 General References Not Available
Enzyme 46 Metabolite References Not Available
Enzyme 47 [top]
Enzyme 47 ID 181
Enzyme 47 Name Dual specificity protein phosphatase 10
Enzyme 47 Synonyms Not Available
Enzyme 47 Gene Name DUSP10
Enzyme 47 Protein Sequence >Dual specificity protein phosphatase 10
MPPSPLDDRVVVALSRPVRPQDLNLCLDSSYLGSAAPGSTSHPPVIATTVVSLKAANLTY
MPSSSGSARSLNCGCSSASCCTVATYDKDNQAPTQAIAAGTATTAIGSSTTCPASQMVNN
SENAGSLSPSGGVGSPMAGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPF
MEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFSKEIIVYDENT
NEPSRVVPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGA
SAASSMLPQSIPSTPDIENAELTPILPFLFLGNEQDAQDLETMQRLNIGYVINVTTHLPL
YHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVI
AYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVET
VV
Enzyme 47 Number of Residues 482
Enzyme 47 Molecular Weight 52388.4
Enzyme 47 Theoretical pI 7.80
Enzyme 47 GO Classification
Function
Process
Component
Enzyme 47 General Function Signal transduction mechanisms
Enzyme 47 Specific Function Involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily
Enzyme 47 Pathways Not Available
Enzyme 47 Reactions Not Available
Enzyme 47 Pfam Domain Function
Enzyme 47 Signals
  • None
Enzyme 47 Transmembrane Regions
  • None
Enzyme 47 Essentiality Not Available
Enzyme 47 GenBank ID Protein 113911868 Link Image
Enzyme 47 UniProtKB/Swiss-Prot ID Q0IID7 Link Image
Enzyme 47 UniProtKB/Swiss-Prot Entry Name DUS10_BOVIN Link Image
Enzyme 47 PDB ID Not Available
Enzyme 47 Cellular Location Not Available
Enzyme 47 Gene Sequence >1449 bp
ATGCCTCCGTCTCCTTTAGACGACAGGGTAGTGGTGGCACTGTCTAGGCCCGTTCGACCT
CAGGATCTCAACCTTTGTTTAGACTCTAGCTACCTTGGCTCTGCCGCCCCTGGCAGTACC
AGCCACCCTCCTGTCATCGCCACCACCGTTGTGTCCCTAAAGGCTGCGAATCTGACGTAT
ATGCCCTCATCCAGCGGCTCTGCCCGCTCCCTGAATTGTGGGTGCAGCAGTGCCAGCTGC
TGCACTGTGGCAACCTACGACAAGGACAATCAGGCCCCAACCCAGGCCATTGCCGCTGGC
ACCGCCACCACCGCCATCGGAAGCTCTACCACCTGTCCTGCCAGCCAGATGGTCAACAAC
AGTGAGAATGCAGGCTCTCTAAGTCCATCAGGTGGGGTGGGCAGCCCCATGGCAGGGACC
CCCAAACAGCTAGCCAGCATCAAAATAATCTACCCCAATGACTTGGCCAAGAAGATGACC
AAATGCAGCAAGAGTCACCTGCCAAGCCAGGGCCCTGTCATCATTGACTGCCGGCCCTTC
ATGGAGTACAACAAAAGTCACATCCAAGGAGCTGTCCACATTAACTGTGCCGATAAGATC
AGCCGGCGGAGACTGCAGCAGGGCAAGATCACTGTCTTAGACTTGATTTCCTGTAGGGAA
GGCAAGGACTCTTTCAAGAGGATCTTTTCCAAAGAAATTATAGTTTACGATGAGAATACC
AATGAGCCGAGCCGAGTGGTACCCTCCCAGCCACTCCACATAGTCCTCGAGTCTCTGAAG
AGAGAAGGCAAAGAACCTCTGGTGTTGAAAGGTGGACTTAGCAGTTTTAAGCAGAACCAT
GAAAACCTCTGTGATAACTCCCTCCAGCTCCAAGAGTGCCGGGAGGTGGGGGGCGGCGCG
TCTGCGGCCTCGAGCATGCTACCTCAATCCATCCCCAGCACCCCCGACATCGAGAACGCG
GAGCTGACACCCATCTTGCCCTTCCTGTTCCTTGGCAACGAGCAGGACGCTCAGGACCTG
GAGACGATGCAGCGGCTGAACATTGGCTACGTCATCAACGTCACCACCCACCTGCCCCTC
TACCACTACGAGAAAGGCCTGTTCAACTACAAGCGGCTGCCGGCCACCGACAGCAACAAG
CAGAACCTGCGGCAGTACTTTGAAGAGGCTTTTGAGTTCATCGAGGAAGCTCACCAGTGT
GGGAAGGGGCTACTCATCCACTGTCAGGCGGGCGTGTCCCGCTCTGCCACCATCGTCATC
GCCTACTTGATGAAGCACACGCGGATGACCATGACTGATGCATATAAATTTGTCAAAGGC
AAACGACCAATTATTTCCCCAAACCTTAACTTCATGGGGCAGTTGCTGGAGTTTGAGGAA
GACCTGAACAATGGTGTGACACCACGAATCCTTACACCAAAGCTGATGGGTGTGGAGACA
GTTGTGTGA
Enzyme 47 GenBank Gene ID BC122694 Link Image
Enzyme 47 GeneCard ID DUSP10 Link Image
Enzyme 47 GenAtlas ID Not Available
Enzyme 47 HGNC ID Not Available
Enzyme 47 Chromosome Location Chromosome:1
Enzyme 47 Locus 1q41
Enzyme 47 SNPs SNPJam Report Link Image
Enzyme 47 General References Not Available
Enzyme 47 Metabolite References Not Available
Enzyme 48 [top]
Enzyme 48 ID 182
Enzyme 48 Name Dynamin-1-like protein
Enzyme 48 Synonyms Not Available
Enzyme 48 Gene Name DNM1L
Enzyme 48 Protein Sequence >Dynamin-1-like protein
MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTR
RPLILQLVHVAPEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEI
RQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIR
ELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAM
DVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLAR
TLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNT
IEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALF
VPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEV
VTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSA
VSRDKSSKVPSALAPASQEPSPAASAEADGKLIQESRRETKNAASGGGGVGDAVQEPTTG
NWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVI
ERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMA
QRRKEAADMLKALQGASQIIAEIRETHLW
Enzyme 48 Number of Residues 749
Enzyme 48 Molecular Weight 83351.0
Enzyme 48 Theoretical pI 7.09
Enzyme 48 GO Classification
Function
Process
Component
Enzyme 48 General Function Involved in GTP binding
Enzyme 48 Specific Function Functions in mitochondrial and peroxisomal division probably by regulating membrane fission. Enzyme hydrolyzing GTP that oligomerizes to form ring-like structures and is able to remodel membranes. May also play a role on organelles of the secretory pathway
Enzyme 48 Pathways Not Available
Enzyme 48 Reactions Not Available
Enzyme 48 Pfam Domain Function
Enzyme 48 Signals
  • None
Enzyme 48 Transmembrane Regions
  • None
Enzyme 48 Essentiality Not Available
Enzyme 48 GenBank ID Protein 86438570 Link Image
Enzyme 48 UniProtKB/Swiss-Prot ID Q2KIA5 Link Image
Enzyme 48 UniProtKB/Swiss-Prot Entry Name DNM1L_BOVIN Link Image
Enzyme 48 PDB ID Not Available
Enzyme 48 Cellular Location Not Available
Enzyme 48 Gene Sequence >2250 bp
ATGGAGGCGCTAATTCCTGTTATTAACAAACTCCAGGACGTCTTCAACACGGTGGGCGCC
GACATCATCCAGCTGCCTCAGATCGTGGTGGTGGGAACGCAGAGCAGTGGAAAGAGCTCA
GTGCTAGAAAGCCTAGTGGGGAGGGACCTGCTTCCCAGAGGCACTGGTATTGTCACCCGG
AGACCTCTCATTCTGCAGCTAGTCCATGTTGCACCTGAAGATAAACGAAAAACAACAGGA
GAAGAAAATGACCCTGCTACATGGAAAAACTCAAGACACCTTTCTAAAGGGGTTGAAGCA
GAAGAATGGGGTAAATTTCTTCACACCAAAAATAAGCTTTACACAGATTTTGATGAAATT
CGACAAGAAATTGAAAATGAAACAGAAAGGATTTCAGGAAATAATAAGGGAGTAAGCCCT
GAACCAATTCATCTTAAGATTTTTTCACCCAATGTTGTCAATCTGACACTTGTGGATTTG
CCAGGAATGACCAAGGTGCCTGTAGGTGATCAACCTAAAGATATTGAGCTTCAAATCAGA
GAGCTCATCCTTCGGTTCATCAGTAATCCAAATTCCATTATCCTCGCTGTCACTGCTGCT
AATACAGATATGGCAACATCAGAGGCACTTAAAATTTCAAGAGAGGTAGATCCAGATGGT
CGCAGAACCCTAGCTGTAATCACTAAACTTGATCTCATGGATGCAGGTACTGATGCCATG
GATGTATTGATGGGAAGGGTTATACCGGTCAAACTGGGAATAATTGGAGTAGTTAACAGG
AGTCAGCTAGATATTAACAATAAGAAGAGTGTAACTGATTCAATCCGTGATGAATATGCT
TTCCTTCAAAAGAAATACCCATCTCTGGCTAATAGAAATGGAACAAAGTATCTTGCCCGG
ACTTTAAACAGGTTACTGATGCATCACATCAGAGATTGCTTACCAGAGTTGAAAACGAGA
ATAAATGTTCTAGCTGCTCAATATCAGTCTCTTCTAAATAGCTATGGTGAACCTGTGGAT
GATAAAAGTGCTACTTTACTCCAGCTTATTACCAAATTTGCCACAGAATATTGTAATACT
ATTGAAGGAACTGCAAAATATATTGAAACGTCAGAGCTATGTGGTGGTGCTCGAATATGT
TATATTTTCCATGAGACTTTTGGGCGAACCTTAGAATCTGTTGACCCTCTTGGTGGCCTT
AACACTATTGACATTTTGACTGCCATTAGAAATGCAACTGGTCCTCGTCCTGCTTTGTTT
GTGCCTGAAGTTTCATTTGAGTTATTGGTCAAACGGCAGATCAAACGTCTGGAAGAGCCC
AGCCTCCGTTGTGTGGAACTGGTTCATGAAGAAATGCAAAGGATCATTCAACACTGTAGC
AATTACAGTACACAGGAGTTGTTGCGGTTCCCTAAACTTCATGATGCCATAGTTGAAGTA
GTGACTTGTCTTCTTCGTAAACGGTTGCCTGTTACAAATGAAATGGTCCATAACTTAGTG
GCAATTGAATTGGCTTATATCAACACAAAACATCCAGACTTTGCTGATGCTTGTGGGTTA
ATGAACAACAATATAGAGGAACAAAGGAGAAACAGGCTAGCAAGAGAATTGCCTTCAGCT
GTATCACGAGACAAGTCTTCTAAAGTTCCAAGTGCTTTGGCACCTGCCTCCCAGGAGCCC
TCCCCTGCTGCTTCTGCTGAGGCTGATGGCAAGTTAATTCAGGAGAGCAGAAGAGAAACT
AAAAATGCTGCATCTGGAGGTGGTGGGGTTGGAGATGCTGTTCAAGAACCAACAACAGGC
AACTGGAGAGGAATGCTGAAAACTTCAAAAGCTGAGGAGTTACTAGCTGAGGAAAAATCA
AAACCAATTCCAATTATGCCAGCCAGTCCACAAAAAGGCCACGCTGTGAATTTGCTGGAT
GTGCCAGTTCCTGTTGCACGAAAACTATCTGCCCGTGAACAGCGAGACTGTGAAGTTATT
GAACGACTCATCAAATCATATTTTCTTATTGTCAGAAAGAATATTCAAGACAGTGTGCCA
AAGGCAGTAATGCATTTTTTGGTTAATCATGTGAAAGATACTCTTCAGAGTGAGTTAGTA
GGACAGCTATATAAATCATCCTTACTGGATGATCTTCTGACTGAATCCGAGGACATGGCA
CAGCGTAGGAAAGAAGCAGCTGATATGCTAAAGGCATTACAAGGAGCCAGTCAAATTATT
GCTGAAATCCGAGAGACTCATCTTTGGTGA
Enzyme 48 GenBank Gene ID BC112710 Link Image
Enzyme 48 GeneCard ID DNM1L Link Image
Enzyme 48 GenAtlas ID Not Available
Enzyme 48 HGNC ID Not Available
Enzyme 48 Chromosome Location Chromosome:1
Enzyme 48 Locus 12p11.21
Enzyme 48 SNPs SNPJam Report Link Image
Enzyme 48 General References Not Available
Enzyme 48 Metabolite References Not Available
Enzyme 49 [top]
Enzyme 49 ID 183
Enzyme 49 Name Tyrosine-protein kinase receptor
Enzyme 49 Synonyms Not Available
Enzyme 49 Gene Name NTRK3
Enzyme 49 Protein Sequence >Tyrosine-protein kinase receptor
LVVLFIMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGM
TRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKD
KMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDL
NKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNC
LVGANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVI
LWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKE
IYKILHALGKATPIYLDILG
Enzyme 49 Number of Residues 380
Enzyme 49 Molecular Weight 43128.8
Enzyme 49 Theoretical pI 8.62
Enzyme 49 GO Classification
Function
Process
Component
Enzyme 49 General Function Involved in ATP binding
Enzyme 49 Specific Function ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Enzyme 49 Pathways Not Available
Enzyme 49 Reactions Not Available
Enzyme 49 Pfam Domain Function
Enzyme 49 Signals
  • None
Enzyme 49 Transmembrane Regions
  • None
Enzyme 49 Essentiality Not Available
Enzyme 49 GenBank ID Protein 158262576 Link Image
Enzyme 49 UniProtKB/Swiss-Prot ID A8KC75 Link Image
Enzyme 49 UniProtKB/Swiss-Prot Entry Name A8KC75_BOVIN Link Image
Enzyme 49 PDB ID Not Available
Enzyme 49 Cellular Location Not Available
Enzyme 49 Gene Sequence Not Available
Enzyme 49 GenBank Gene ID BC154388 Link Image
Enzyme 49 GeneCard ID NTRK3 Link Image
Enzyme 49 GenAtlas ID Not Available
Enzyme 49 HGNC ID Not Available
Enzyme 49 Chromosome Location Chromosome:1
Enzyme 49 Locus 15q25
Enzyme 49 SNPs SNPJam Report Link Image
Enzyme 49 General References Not Available
Enzyme 49 Metabolite References Not Available
Enzyme 50 [top]
Enzyme 50 ID 184
Enzyme 50 Name Serine/threonine protein phosphatase
Enzyme 50 Synonyms Not Available
Enzyme 50 Gene Name Not Available
Enzyme 50 Protein Sequence >Serine/threonine protein phosphatase
HLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSP
ANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKI
KYS
Enzyme 50 Number of Residues 123
Enzyme 50 Molecular Weight 14354.6
Enzyme 50 Theoretical pI 6.51
Enzyme 50 GO Classification
Function
Process
Component
Enzyme 50 General Function Involved in iron ion binding
Enzyme 50 Specific Function A phosphoprotein + H(2)O = a protein + phosphate
Enzyme 50 Pathways Not Available
Enzyme 50 Reactions Not Available
Enzyme 50 Pfam Domain Function
Enzyme 50 Signals
  • None
Enzyme 50 Transmembrane Regions
  • None
Enzyme 50 Essentiality Not Available
Enzyme 50 GenBank ID Protein 165974062 Link Image
Enzyme 50 UniProtKB/Swiss-Prot ID A9ZTK8 Link Image
Enzyme 50 UniProtKB/Swiss-Prot Entry Name A9ZTK8_BOVIN Link Image
Enzyme 50 PDB ID 1AUI Link Image
Enzyme 50 PDB File Show
Enzyme 50 3D Structure
Enzyme 50 Cellular Location Not Available
Enzyme 50 Gene Sequence Not Available
Enzyme 50 GenBank Gene ID AB375865 Link Image
Enzyme 50 GeneCard ID Not Available
Enzyme 50 GenAtlas ID Not Available
Enzyme 50 HGNC ID Not Available
Enzyme 50 Chromosome Location Not Available
Enzyme 50 Locus Not Available
Enzyme 50 SNPs SNPJam Report Link Image
Enzyme 50 General References Not Available
Enzyme 50 Metabolite References Not Available
Enzyme 51 [top]
Enzyme 51 ID 185
Enzyme 51 Name Activated CDC42 kinase 1
Enzyme 51 Synonyms
  1. ACK-1
  2. Tyrosine kinase non-receptor protein 2
  3. Activated CDC42 kinase 2
Enzyme 51 Gene Name TNK2
Enzyme 51 Protein Sequence >Activated CDC42 kinase 1
MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLW
EAVKRRKAMCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPTPGGSAGEGSLQSLTCL
IGEKDLHLFEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNA
MHSLDHRNLIRLYGVVLTPPMKTVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGM
GYLEAKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPE
SLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDI
YNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRA
ENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWGFPD
KIDELYLGNPMDPPDLLSVELSTSRPTQHLGRVKKPTYDPVSEDQDPLSSDFKRLGLRKP
GLPRGLWLAKPSARVPGTKAGRGGGEVTLIDFGEEPVVPAPRPCAPSLAQLAMDACSLLD
KTPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEVCSINSTLVGAGVSA
EPSQGETNYAFVPEPARLLPPLEDNLFLPPQSGGKPPNSAQTAEIFQALQQECMRQLQVP
PGSLVPSPSPGGDDKPQVPPRVPIPPRPTRSRGELSPVPPGEEEMGRWPGPASPPRVPPR
EPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAG
PCILPIVRDGKKVSSTHYYLLPERPPYLERYQRFLHEAQSPRGPDPTPIPLLLPPPSTPA
PAAPTATVRPMPQAAPDPKANFSSNNSNPGARPSSLRATARLPQRGYPGDGPEAGRPADK
IQMLQAMVHGVTTEECQAALQSHSWSVQRAAQYLKVEQLFGLGLRPRGECHNVLEMFDWN
LEQAGCHLLGSCGPAHHKR
Enzyme 51 Number of Residues 1039
Enzyme 51 Molecular Weight 114866.9
Enzyme 51 Theoretical pI 7.38
Enzyme 51 GO Classification
Function
Process
Component
Enzyme 51 General Function Involved in ATP binding
Enzyme 51 Specific Function Downstream effector of CDC42 which mediates CDC42- dependent cell migration via phosphorylation of BCAR1. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR. Participates in clathrin-mediated endocytosis. May be involved both in adult synaptic function and plasticity and in brain development
Enzyme 51 Pathways Not Available
Enzyme 51 Reactions Not Available
Enzyme 51 Pfam Domain Function
Enzyme 51 Signals
  • None
Enzyme 51 Transmembrane Regions
  • None
Enzyme 51 Essentiality Not Available
Enzyme 51 GenBank ID Protein 2078388 Link Image
Enzyme 51 UniProtKB/Swiss-Prot ID Q17R13 Link Image
Enzyme 51 UniProtKB/Swiss-Prot Entry Name ACK1_BOVIN Link Image
Enzyme 51 PDB ID 1U54 Link Image
Enzyme 51 PDB File Show
Enzyme 51 3D Structure
Enzyme 51 Cellular Location Not Available
Enzyme 51 Gene Sequence >2244 bp
ATGCAGCCAGAGGAGGGCACAGGCTGGCTGCTAGAGCTGCTGTCCGAGGTGCAGCTCCAG
CAGTATTTCCTGCGCCTCCGCGACGACCTCAACGTCACCCGCCTGTCCCACTTTGAGTAT
GTCAAGAACGAGGACCTGGAGAAGATCGGCATGGGCCGGCCCGGCCAGCGGCGGCTATGG
GAGGCCGTGAAGAGGAGGAAGGCCATGTGCAAACGCAAGTCCTGGATGAGCAAGGTGTTC
AGTGGAAAGCGGCTGGAGGCTGAGTTCCCCCCTCATCACTCTCAGAGCACCTTCCGGAAG
ACCTCGCCCACCCCAGGGGGCTCTGCTGGGGAGGGGTCCCTGCAGAGCCTCACCTGCCTC
ATTGGGGAGAAGGACCTGCATCTCTTCGAGAAGCTGGGAGATGGCTCCTTTGGCGTGGTG
CGCAGGGGCGAGTGGGACGCCCCCTCGGGGAAGACGGTGAGCGTGGCTGTGAAGTGCCTG
AAGCCCGACGTGCTGAGCCAGCCGGAGGCCATGGACGACTTCATCCGGGAGGTCAACGCC
ATGCACTCGCTTGACCACCGAAACCTCATTCGCCTCTACGGGGTGGTGCTCACACCGCCC
ATGAAGATGGTGACAGAGCTGGCACCTCTGGGATCATTGTTGGACCGGCTGCGCAAGCAC
CAGGGCCACTTCCTGCTGGGCACCCTGAGCCGCTACGCTGTGCAGGTGGCTGAGGGCATG
GGCTACCTGGAGGCCAAGCGCTTCATCCACCGGGACCTGGCCGCCCGAAATCTGCTGTTG
GCCACCCGCGACCTGGTCAAGATAGGGGACTTCGGGCTGATGCGAGCACTGCCCCAGAAC
GACGACCACTACGTCATGCAGGAACATCGCAAGGTGCCCTTTGCCTGGTGTGCCCCAGAG
AGCCTGAAGACACGCACCTTCTCCCACGCCAGCGACACCTGGATGTTTGGGGTCACGCTG
TGGGAGATGTTCACCTATGGCCAGGAGCCCTGGATTGGCCTCAATGGCAGTCAGATCCTG
CATAAGATTGACAAGGAGGGGGAGCGTCTACCCCGGCCGGAGGACTGCCCCCAGGACATC
TACAATGTCATGGTCCAGTGCTGGGCTCACAAGCCCGAGGACAGACCCACGTTTGTGGCC
CTGCGGGACTTCCTGCTGGAGGCTCAGCCCACCGACATGCGGGCCCTTCAGGACTTCGAA
GAACCTGACAAGCTGCACATCCAGATGAATGATGTCATCACCGTCATCGAGGGGAGGGCT
GAGAATTACTGGTGGCGTGGGCAGAACACGCGGACGCTGTGCGTGGGGCCCTTCCCTCGC
AACGTGGTGACCTCCGTGGCTGGTCTGTCAGCCCAGGACATCAGCCAGCCACTGCAGAAT
AGCTTCATCCACACGGGGCATGGCGACAGTGACCCCCGCCACTGCTGGGGCTTCCCTGAC
AAGATTGATGAACTGTATCTGGGAAACCCCATGGACCCTCCTGACCTGCTGAGCGTGGAA
CTGAGCACATCCAGGCCCACCCAGCATCTGGGCAGGGTGAAAAGGGAGCCTCCACCTCGC
CCTCCTCAGCCTGCCATCTTCACTCAGAAACCAACCTACGACCCCGTGAGTGAGGACCAA
GACCCCCTGTCCAGCGACTTCAAGAAGCTGGGCCTGCGAAAGCCAGGACTGCCCCGTGGG
CTGTGGCTCGCGAAGCCCTCAGCCCGGGTGCCAGGCACCAAGGCCGGCCGCGGTGGTGGC
GAGGTCACGCTCATCGATTTCGGCGAGGAGCCTGTTGTGCCGGCCCCACGGCCCTGTGCC
CCATCACTGGCGCAGCTGGCCATGGACGCCTGTTCCTTGCTGGACAAGACCCCGCCACAG
AGCCCTACACGGGCCCTGCCCCGGCCCCTGCATCCCACGCCTGTGGTGGACTGGGATGCA
CGCCCACTGCCCCCGCCTCCCGCCTACGATGACGTGGCCCAGGATGAGGATGACTTCGAG
GTCTGCTCCATCAACAGCACCCTCGTGGGCGCCGGGGTCTCTGCTGAGCCCAGCCAGGGC
GAGACCAACTATGCCTTTGTGCCTGAGCCGGCGAGGCTCCTCCCCCCCGCTGGAGGACAA
CCTGTTCCTCCCACCCCAGAGTGGGGGCAAGCCACCCAACTCGGCCCAAACCGCAGAGAT
CTTCCAGGCGCTGCAGCAGGAATGCATGCGGCAGCTACAGGTCCCGCCTGGCTCTCTGGT
CCCCTCACCCAGCCCTGGGGGTGA
Enzyme 51 GenBank Gene ID U96722 Link Image
Enzyme 51 GeneCard ID TNK2 Link Image
Enzyme 51 GenAtlas ID Not Available
Enzyme 51 HGNC ID Not Available
Enzyme 51 Chromosome Location Chromosome:3
Enzyme 51 Locus 3q29
Enzyme 51 SNPs SNPJam Report Link Image
Enzyme 51 General References
  1. [PubMed Link Image]
Enzyme 51 Metabolite References Not Available
Enzyme 52 [top]
Enzyme 52 ID 186
Enzyme 52 Name Integrin-linked protein kinase
Enzyme 52 Synonyms Not Available
Enzyme 52 Gene Name ILK
Enzyme 52 Protein Sequence >Integrin-linked protein kinase
MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI
NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV
ANGALVSICNKYGEMPVDKAKPPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG
TLNKHSGIDFKQLNFLAKLNENHSGELWKGRWQGNDIVVKMLKVRDWSTRKSRDFNEECP
RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD
MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA
LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH
VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
Enzyme 52 Number of Residues 452
Enzyme 52 Molecular Weight 51446.9
Enzyme 52 Theoretical pI 8.18
Enzyme 52 GO Classification
Function
Process
Component
Enzyme 52 General Function Involved in ATP binding
Enzyme 52 Specific Function Receptor-proximal protein kinase regulating integrin- mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B
Enzyme 52 Pathways Not Available
Enzyme 52 Reactions Not Available
Enzyme 52 Pfam Domain Function
Enzyme 52 Signals
  • None
Enzyme 52 Transmembrane Regions
  • None
Enzyme 52 Essentiality Not Available
Enzyme 52 GenBank ID Protein 74356509 Link Image
Enzyme 52 UniProtKB/Swiss-Prot ID Q3SWY2 Link Image
Enzyme 52 UniProtKB/Swiss-Prot Entry Name ILK_BOVIN Link Image
Enzyme 52 PDB ID Not Available
Enzyme 52 Cellular Location Not Available
Enzyme 52 Gene Sequence >1359 bp
ATGGACGACATTTTCACTCAGTGCCGGGAGGGCAACGCGGTTGCGGTCCGCCTGTGGCTG
GACAACACGGAGAACGACCTCAACCAGGGGGACGATCATGGCTTCTCCCCCTTGCACTGG
GCCTGCCGAGAAGGCCGATCTGCTGTGGTTGAGATGCTGATCATGCGGGGGGCACGAATC
AATGTGATGAACCGTGGGGATGATACCCCTCTGCACCTGGCAGCCAGTCATGGGCACCGT
GATATTGTACAGAAGCTGCTGCAGTACAAAGCTGACATCAATGCGGTGAATGAGCATGGG
AATGTGCCCCTGCACTATGCCTGTTTCTGGGGCCAAGATCAGGTGGCAGAGGACCTCGTG
GCAAATGGGGCCCTTGTCAGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCT
AAGCCACCCCTGAGAGAGCTGCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTGAAC
CGTATACCATACAAGGACACATTCTGGAAGGGGACTACCCGCACTCGGCCCCGAAATGGG
ACTCTGAACAAACACTCCGGCATTGACTTCAAACAGCTCAACTTCCTGGCGAAGCTCAAC
GAGAATCACTCTGGAGAGCTATGGAAGGGCCGCTGGCAGGGCAATGACATTGTCGTGAAG
ATGCTAAAGGTTCGAGACTGGAGTACAAGGAAGAGCAGAGACTTCAATGAGGAGTGTCCC
CGGCTCAGGATTTTCTCACATCCCAATGTGCTCCCAGTGCTTGGTGCCTGTCAGTCTCCA
CCTGCTCCTCACCCCACCCTCATCACACACTGGATGCCATACGGATCCCTGTACAATGTG
CTACATGAAGGCACCAATTTTGTTGTGGACCAGAGCCAGGCTGTGAAGTTTGCATTGGAC
ATGGCAAGGGGCATGGCCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCACTC
AACAGCCGTAGTGTAATGATTGATGAGGACATGACTGCTCGAATCAGTATGGCCGACGTC
AAGTTCTCCTTCCAGTGCCCCGGGCGCATGTATGCACCTGCCTGGGTGGCTCCTGAAGCT
CTGCAAAAGAAGCCTGAAGACACAAACAGACGCTCAGCAGATATGTGGAGTTTTGCAGTG
CTTCTATGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAACATGGAAATT
GGAATGAAGGTGGCACTGGAAGGCCTTCGGCCTACCATCCCACCAGGCATTTCCCCCCAC
GTATGTAAACTCATGAAGATCTGCATGAATGAAGACCCTGCTAAGCGACCCAAGTTTGAC
ATGATCGTGCCTATCCTGGAGAAGATGCAGGACAAGTAG
Enzyme 52 GenBank Gene ID BC104603 Link Image
Enzyme 52 GeneCard ID ILK Link Image
Enzyme 52 GenAtlas ID Not Available
Enzyme 52 HGNC ID Not Available
Enzyme 52 Chromosome Location Chromosome:1
Enzyme 52 Locus 11p15.5-p15.4
Enzyme 52 SNPs SNPJam Report Link Image
Enzyme 52 General References Not Available
Enzyme 52 Metabolite References Not Available
Enzyme 53 [top]
Enzyme 53 ID 187
Enzyme 53 Name Dual specificity protein phosphatase 18
Enzyme 53 Synonyms Not Available
Enzyme 53 Gene Name DUSP18
Enzyme 53 Protein Sequence >Dual specificity protein phosphatase 18
MTASPCAFPVQFRQPSVSGLSQITSSLYISSGVAANNRLMLSSNRISTVINVSVEVVNAL
YEDIHYVQVPVADTPTSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
KYHAMSLLDAHTWTKSCRPIIRPNNGFWEQLIHYEFQLFGRNTVHMVSSPVGMIPDIYEK
EVRQMIPL
Enzyme 53 Number of Residues 188
Enzyme 53 Molecular Weight 21028.1
Enzyme 53 Theoretical pI 7.57
Enzyme 53 GO Classification
Function
Process
Component
Enzyme 53 General Function Signal transduction mechanisms
Enzyme 53 Specific Function Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine
Enzyme 53 Pathways Not Available
Enzyme 53 Reactions Not Available
Enzyme 53 Pfam Domain Function
Enzyme 53 Signals
  • None
Enzyme 53 Transmembrane Regions
  • None
Enzyme 53 Essentiality Not Available
Enzyme 53 GenBank ID Protein 60650250 Link Image
Enzyme 53 UniProtKB/Swiss-Prot ID Q5BIP9 Link Image
Enzyme 53 UniProtKB/Swiss-Prot Entry Name DUS18_BOVIN Link Image
Enzyme 53 PDB ID Not Available
Enzyme 53 Cellular Location Not Available
Enzyme 53 Gene Sequence >567 bp
ATGACAGCATCCCCGTGTGCCTTCCCAGTTCAGTTCCGGCAGCCCTCGGTCAGTGGCCTC
TCACAGATCACCAGTAGCCTGTATATCAGCAGCGGGGTGGCCGCCAACAACAGGCTCATG
CTCTCCAGCAACCGCATCAGCACGGTCATCAATGTCTCAGTGGAGGTGGTGAACGCCTTG
TACGAGGACATTCACTATGTGCAGGTGCCCGTGGCCGACACGCCCACCTCGCGGCTCTGT
GACTTCTTCGACCCCATCGCAGACCACATCCACAGCGTGGAGATGAAGCAGGGCCGCACC
CTGCTGCACTGCGCCGCCGGCGTCAGCCGCTCGGCTGCCCTCTGCCTCGCCTATCTCATG
AAGTACCACGCCATGTCCCTGCTGGACGCCCACACGTGGACCAAGTCCTGCCGGCCCATC
ATCCGGCCCAACAACGGCTTTTGGGAGCAGCTCATCCACTATGAGTTCCAGCTATTTGGC
AGGAATACCGTGCACATGGTCAGCTCCCCCGTGGGCATGATCCCTGACATCTACGAGAAG
GAGGTCCGTCAGATGATTCCACTCTGA
Enzyme 53 GenBank Gene ID BT021175 Link Image
Enzyme 53 GeneCard ID DUSP18 Link Image
Enzyme 53 GenAtlas ID Not Available
Enzyme 53 HGNC ID Not Available
Enzyme 53 Chromosome Location Chromosome:2
Enzyme 53 Locus 22q12.2
Enzyme 53 SNPs SNPJam Report Link Image
Enzyme 53 General References
  1. [PubMed Link Image]
Enzyme 53 Metabolite References Not Available
Enzyme 54 [top]
Enzyme 54 ID 188
Enzyme 54 Name Serine/threonine protein phosphatase
Enzyme 54 Synonyms Not Available
Enzyme 54 Gene Name PPP3CC
Enzyme 54 Protein Sequence >Serine/threonine protein phosphatase
MSGRNLHLSTTERVIKAVPFPPTQRLSLKEVFENGKPKIDVLKNHLVKEGRLEEEVALKI
INDGAAILRQEKTMIEVDAPVTVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEQVYDACMETFDC
LPLAALLNQQFLCVHGGMSPEITCLDDIRKLDRFKEPPAFGPVCDLLWSDPSEDYGNEKT
LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQMTGFPSLIT
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
LVNILNICSDDELISDDELEGGTTVRKEIIKNKIRAIGKMARVFSILREESESVLTLKGL
TPTGTLPLGVLSGGKQTIETAIRGFSLQHRIRSFEEARGLDRINERMPPRKDSQYFDGPV
KLVQANAAHRSDKGRRASNDSEPCGGTGGSKT
Enzyme 54 Number of Residues 512
Enzyme 54 Molecular Weight 58179.0
Enzyme 54 Theoretical pI 6.82
Enzyme 54 GO Classification
Function
Process
Component
Enzyme 54 General Function Signal transduction mechanisms
Enzyme 54 Specific Function A phosphoprotein + H(2)O = a protein + phosphate
Enzyme 54 Pathways Not Available
Enzyme 54 Reactions Not Available
Enzyme 54 Pfam Domain Function
Enzyme 54 Signals
  • None
Enzyme 54 Transmembrane Regions
  • None
Enzyme 54 Essentiality Not Available
Enzyme 54 GenBank ID Protein 146186586 Link Image
Enzyme 54 UniProtKB/Swiss-Prot ID A5D7T5 Link Image
Enzyme 54 UniProtKB/Swiss-Prot Entry Name A5D7T5_BOVIN Link Image
Enzyme 54 PDB ID Not Available
Enzyme 54 Cellular Location Not Available
Enzyme 54 Gene Sequence >1539 bp
ATGTCCGGGAGGAACCTCCACCTCTCCACCACCGAACGCGTCATCAAAGCTGTCCCCTTT
CCTCCGACCCAGCGGCTTTCTTTGAAGGAAGTATTTGAGAATGGGAAACCTAAAATTGAT
GTTTTGAAAAACCATTTGGTGAAGGAAGGGCGACTGGAAGAGGAAGTAGCCTTAAAAATA
ATCAATGATGGGGCTGCCATACTGAGACAAGAGAAGACTATGATAGAAGTAGATGCTCCA
GTCACGGTATGTGGTGACATTCATGGACAATTCTTTGACCTGATGAAGTTGTTTGAAGTT
GGAGGATCACCTAGTAATACACGCTACCTCTTTCTGGGTGACTACGTGGACAGAGGCTAT
TTCAGTATAGAGTGTGTGCTGTATTTATGGAGTTTAAAGATCAATCATCCCAAAACATTG
TTTCTGCTTCGAGGAAATCATGAATGCAGGCATCTTACAGAATATTTTACCTTCAAACAG
GAATGTCGAATCAAATATTCTGAACAGGTGTACGATGCGTGTATGGAAACATTTGACTGT
CTTCCTCTTGCTGCCCTCTTAAACCAGCAGTTTCTGTGTGTACATGGAGGAATGTCACCT
GAAATTACTTGTTTAGATGACATTCGGAAATTAGACAGGTTTAAAGAACCTCCAGCCTTT
GGGCCAGTGTGTGACCTGCTTTGGTCTGATCCCTCCGAGGATTATGGCAATGAAAAGACC
TTGGAACACTATACCCACAACACTGTCCGAGGGTGCTCTTATTTTTACAGTTACCCTGCA
GTTTGTGAATTTCTGCAGAACAATAATTTGCTCTCAATAATCAGAGCCCATGAAGCCCAA
GATGCCGGGTATCGAATGTACAGGAAGAGCCAAATGACGGGTTTTCCATCGCTCATTACA
ATTTTCTCTGCACCCAATTACCTAGATGTCTATAACAATAAAGCTGCTGTGTTAAAATAT
GAAAACAACGTCATGAATATCAGGCAGTTTAACTGTTCTCCACACCCCTACTGGCTTCCA
AACTTTATGGATGTTTTCACGTGGTCTTTGCCTTTTGTCGGGGAAAAAGTTACAGAGATG
CTGGTTAACATTCTCAACATATGCTCTGATGATGAATTGATTTCTGATGATGAACTTGAA
GGAGGCACTACAGTTCGCAAGGAGATCATCAAGAATAAAATCAGAGCTATTGGGAAGATG
GCACGGGTCTTTTCAATTCTTCGGGAAGAGAGTGAGAGCGTGCTAACTCTCAAGGGCCTG
ACTCCTACAGGGACACTGCCTTTGGGTGTCCTCTCAGGAGGAAAGCAGACTATTGAGACA
GCCATCAGAGGGTTTTCGCTTCAGCACAGGATCCGAAGTTTTGAAGAAGCCCGAGGTCTC
GACCGGATTAATGAGCGGATGCCACCCCGCAAAGATAGCCAGTACTTTGATGGGCCGGTG
AAACTGGTCCAAGCCAACGCTGCACACAGGAGCGACAAGGGAAGAAGAGCCAGTAATGAC
TCAGAGCCCTGCGGTGGCACTGGTGGCTCCAAGACTTAA
Enzyme 54 GenBank Gene ID BC140675 Link Image
Enzyme 54 GeneCard ID PPP3CC Link Image
Enzyme 54 GenAtlas ID Not Available
Enzyme 54 HGNC ID Not Available
Enzyme 54 Chromosome Location Chromosome:8
Enzyme 54 Locus 8p21.3
Enzyme 54 SNPs SNPJam Report Link Image
Enzyme 54 General References Not Available
Enzyme 54 Metabolite References Not Available
Enzyme 55 [top]
Enzyme 55 ID 189
Enzyme 55 Name ATP synthase subunit beta, mitochondrial
Enzyme 55 Synonyms Not Available
Enzyme 55 Gene Name ATP5B
Enzyme 55 Protein Sequence >ATP synthase subunit beta, mitochondrial
MLGLVGRVVAASASGALRGLSPSAPLPQAQLLLRAAPAALQPARDYAAQASPSPKAGATT
GRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLV
RGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQ
EILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERT
REGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQD
VLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAI
YVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDV
ARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGK
LVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHS
Enzyme 55 Number of Residues 528
Enzyme 55 Molecular Weight 56283.0
Enzyme 55 Theoretical pI 4.92
Enzyme 55 GO Classification
Function
Process
Component
Enzyme 55 General Function Energy production and conversion
Enzyme 55 Specific Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits
Enzyme 55 Pathways Not Available
Enzyme 55 Reactions Not Available
Enzyme 55 Pfam Domain Function
Enzyme 55 Signals
  • None
Enzyme 55 Transmembrane Regions
  • None
Enzyme 55 Essentiality Not Available
Enzyme 55 GenBank ID Protein 162711 Link Image
Enzyme 55 UniProtKB/Swiss-Prot ID P00829 Link Image
Enzyme 55 UniProtKB/Swiss-Prot Entry Name ATPB_BOVIN Link Image
Enzyme 55 PDB ID 1W0K Link Image
Enzyme 55 PDB File Show
Enzyme 55 3D Structure
Enzyme 55 Cellular Location Not Available
Enzyme 55 Gene Sequence >1587 bp
ATGTTGGGACTTGTGGGTCGTGTGGTTGCTGCCTCGGCCTCCGGGGCCTTGCGGGGACTC
AGCCCTTCAGCGCCGCTACCGCAAGCCCAGCTTTTACTGCGGGCCGCTCCTGCAGCGCTC
CAGCCTGCCAGAGACTATGCCGCTCAAGCATCTCCATCGCCAAAGGCCGGCGCCACCACT
GGGCGCATCGTGGCGGTCATTGGTGCAGTGGTGGACGTCCAGTTTGATGAGGGACTGCCT
CCCATCCTAAATGCCCTGGAGGTGCAAGGCAGGGAGACCAGGCTGGTTTTGGAGGTGGCC
CAGCATTTGGGTGAGAGCACAGTAAGGACCATTGCTATGGATGGTACAGAAGGCTTGGTT
AGAGGTCAGAAAGTCCTGGATTCTGGTGCACCAATCAGAATTCCTGTTGGCCCTGAGACC
TTGGGTAGAATCATGAACGTCATTGGAGAACCTATTGATGAGAGGGGTCCCATCAAAACC
AAGCAATTTGCTGCTATTCATGCTGAGGCTCCTGAATTCGTGGAGATGAGTGTTGAACAA
GAAATTCTGGTTACTGGTATTAAGGTTGTAGATCTGCTGGCTCCATATGCCAAGGGTGGC
AAAATTGGGCTTTTTGGTGGTGCTGGAGTCGGCAAGACAGTACTGATCATGGAGTTAATC
AACAATGTTGCCAAAGCCCATGGTGGTTACTCTGTGTTTGCTGGTGTTGGTGAAAGGACC
CGTGAGGGCAATGACTTATACCATGAAATGATTGAGTCTGGTGTTATCAACTTAAAAGAT
GCTACCTCTAAGGTAGCGCTGGTGTACGGTCAAATGAATGAACCACCTGGTGCTCGGGCC
CGGGTTGCTCTGACTGGGCTGACTGTAGCTGAGTACTTCAGAGACCAAGAAGGTCAAGAT
GTGTTGCTGTTTATTGATAACATCTTTCGCTTCACCCAGGCTGGCTCAGAGGTGTCTGCT
TTATTGGGCAGAATCCCTTCTGCTGTGGGTTATCAGCCTACCCTGGCCACTGACATGGGT
ACCATGCAGGAAAGAATCACCACCACCAAAAAGGGATCTATCACCTCTGTACAGGCTATC
TATGTGCCTGCTGATGACTTGACGGATCCTGCCCCGGCCACTACCTTTGCCCATTTGGAT
GCTACCACTGTGTTGTCCCGTGCTATTGCTGAGCTGGGCATCTATCCAGCTGTGGATCCT
TTGGACTCCACGTCTCGCATCATGGATCCCAACATTGTTGGCAGTGAGCATTATGATGTT
GCCCGTGGGGTGCAAAAGATTCTGCAGGACTACAAATCCCTCCAGGACATCATTGCTATC
CTGGGTATGGATGAACTTTCTGAAGAAGATAAGTTAACTGTGTCTCGTGCACGGAAAATC
CAGCGTTTCTTGTCTCAGCCATTCCAGGTGGCTGAGGTCTTTACTGGTCATTTGGGGAAG
CTGGTACCCCTCAAGGAGACCATCAAAGGATTCCAGCAGATTTTGGCAGGTGAATATGAC
CATCTCCCAGAACAGGCCTTCTATATGGTGGGACCCATTGAAGAAGCTGTGGCAAAAGCT
GATAAGTTGGCTGAAGAGCACTCATGA
Enzyme 55 GenBank Gene ID M20929 Link Image
Enzyme 55 GeneCard ID ATP5B Link Image
Enzyme 55 GenAtlas ID Not Available
Enzyme 55 HGNC ID Not Available
Enzyme 55 Chromosome Location Chromosome:1
Enzyme 55 Locus 12q13.13
Enzyme 55 SNPs SNPJam Report Link Image
Enzyme 55 General References
  1. [PubMed Link Image]
Enzyme 55 Metabolite References Not Available
Enzyme 56 [top]
Enzyme 56 ID 190
Enzyme 56 Name Putative tyrosine-protein phosphatase auxilin
Enzyme 56 Synonyms
  1. DnaJ homolog subfamily C member 6
Enzyme 56 Gene Name DNAJC6
Enzyme 56 Protein Sequence >Putative tyrosine-protein phosphatase auxilin
MDSSGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGD
LDFTYVTSRIIVMSFPLDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHS
RVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCN
LYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPVPF
FNKQRNGCRPYCDVLIGETKIYTTCADFERMKEYRVQDGKIFIPLSITVQGDVVVSMYHL
RSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDV
ELQPHDKVMELTPPWEHYCTKDVNPSILFSSHQEHQDTLVLGGQAPIDIPPDNPRHFGQG
GFFSTLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHAARKPSK
KQQEPAAPAPPEDVDLLGLEGSAVSKNFSSPAAPPSNSELLSDLFGGGGAAGPVQSGQSG
VDDVFHPSGPTSTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTA
SASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGAWDWHTKPGGFGMGSKSAATSPTGSS
HGTPTHQNKPQTLDPFADLGTLGGSSFASKPSTPTGLGGGFPPLSSPQKASPQPMGGGWQ
QGGGYNWQQTQSKPQSSMPHSSPQNRPNYNVSFSSMPGGQNERGKAAANLEGKQKAADFE
DLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTV
LWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSE
FENQGQKPLY
Enzyme 56 Number of Residues 910
Enzyme 56 Molecular Weight 99511.2
Enzyme 56 Theoretical pI 7.27
Enzyme 56 GO Classification
Function
Process
Component
Enzyme 56 General Function Involved in heat shock protein binding
Enzyme 56 Specific Function Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles
Enzyme 56 Pathways Not Available
Enzyme 56 Reactions Not Available
Enzyme 56 Pfam Domain Function
Enzyme 56 Signals
  • None
Enzyme 56 Transmembrane Regions
  • None
Enzyme 56 Essentiality Not Available
Enzyme 56 GenBank ID Protein 485269 Link Image
Enzyme 56 UniProtKB/Swiss-Prot ID Q27974 Link Image
Enzyme 56 UniProtKB/Swiss-Prot Entry Name AUXI_BOVIN Link Image
Enzyme 56 PDB ID 1N4C Link Image
Enzyme 56 PDB File Show
Enzyme 56 3D Structure
Enzyme 56 Cellular Location Not Available
Enzyme 56 Gene Sequence >2733 bp
ATGGACAGCTCAGGTGCCTCATCTCCAGACATGGAGCCCAGCTATGGCGGAGGTCTTTTT
GACATGGTGAAAGGAGGGGCAGGGAGGCTCTTTAGCAACCTAAAGGACAACTTGAAAGAC
ACTCTCAAAGACACGTCTTCCAGAGTTATACAATCTGTTACCAGCTACACGAAAGGAGAT
TTAGACTTCACTTATGTTACCTCCAGAATTATTGTGATGTCCTTTCCTCTGGACAGTGTT
GACATAGGATTCAGGAATCAGGTTGATGATATTCGAAGCTTTTTGGATTCCAGACATCTT
GACCACTACACGGTATACAATCTGTCGCCCAAGTCTTATCGAACTGCCAAGTTTCACAGC
AGGGTCTCAGAATGCAGTTGGCCCATCAGGCAGGCCCCCAGCCTGCACAACCTCTTTGCT
GTGTGTCGGAATATGTATAACTGGCTACTACAGAATCCCAAAAACGTCTGTGTTGTCCAC
TGCTTGGATGGACGGGCAGCATCATCGATTCTGGTTGGTGCTATGTTCATTTTCTGTAAT
CTCTACTCTACTCCTGGCCCAGCCGTTCGATTGCTCTACGCAAAGCGACCAGGAATTGGA
CTTTCACCATCCCACAGGAGGTACCTGGGCTACATGTGTGACCTCCTAGCAGACAAACCC
TACCGCCCTCACTTCAAGCCTCTCACAATTAAGTCGATCACTGTCAGTCCAGTTCCTTTT
TTCAACAAACAGAGAAATGGATGTCGCCCTTACTGCGATGTACTGATTGGAGAAACCAAA
ATATATACAACCTGTGCAGATTTTGAACGAATGAAGGAATACCGTGTCCAAGATGGAAAA
ATCTTCATTCCTTTGAGCATCACTGTGCAAGGAGATGTGGTTGTTTCCATGTATCACTTG
AGGTCAACAATTGGAAGCAGGCTACAGGCTAAGGTGACCAACACTCAAATATTTCAGCTT
CAGTTTCATACTGGATTCATTCCACTGGACACAACAGTTTTAAAGTTCACCAAGCCTGAG
TTGGATGCATGTGATGTACCAGAAAAATATCCTCAGCTATTTCAGGTAACTCTGGATGTA
GAACTACAGCCTCACGACAAAGTGATGGAGCTAACCCCACCGTGGGAACATTACTGCACA
AAAGATGTCAACCCCAGCATCCTCTTCTCTTCTCACCAGGAGCATCAAGATACTCTGGTC
TTAGGAGGACAGGCTCCAATAGATATCCCTCCAGATAATCCCAGACATTTTGGGCAAGGT
GGCTTCTTTTCCACTCTCTGCTGGCAAGATCAGAAATCGGAGAAGTCATTCTGCGAGGAG
GACCACGCTGCCCTAGTGAATCAGGAGAGTGAGCAGTCAGACGATGAGCTTCTGACGCTG
TCCAGCCCACATGGCAATGCCAATGGTGACAAACCTCACGCAGCCAGGAAGCCCAGCAAA
AAGCAGCAGGAGCCAGCTGCCCCTGCACCCCCTGAGGATGTGGATCTTCTGGGTCTAGAA
GGGTCTGCTGTGAGTAAGAACTTCTCTTCGCCGGCAGCTCCTCCCTCCAATTCCGAACTT
CTGAGTGACCTGTTCGGGGGCGGAGGTGCAGCCGGTCCCGTCCAGTCTGGACAGTCAGGG
GTGGACGACGTGTTTCACCCGAGTGGACCTACATCCACCCAGTCCACACCACGCCGATCT
GCCACCTCCACCTCTGCATCTCCAACACTGAGAGTAGGAGAAGGTGCCACCTTTGACCCA
TTTGGAGCACCTTCTAAACCATCAGGTCAAGATTTGCTGGGTTCTTTTTTGAACACAGCC
AGTGCTTCCAGTGACCCCTTTCTTCAGCCTACGAGGAGTCCTTCTCCTACAGTGCATGCT
TCTAGTACCCCTGCTGTGAACATTCAGCCAGATGTTTCAGGAGCCTGGGACTGGCATACC
AAACCAGGAGGTTTTGGAATGGGAAGCAAATCAGCTGCCACCAGCCCAACAGGCTCCTCG
CATGGTACTCCCACCCATCAAAACAAACCCCAGACTCTGGACCCTTTTGCTGACCTTGGG
ACATTAGGTGGTTCTTCATTTGCCAGCAAACCTTCCACACCAACTGGATTGGGTGGTGGA
TTTCCACCTCTCAGCTCGCCACAGAAAGCATCTCCCCAGCCCATGGGTGGGGGGTGGCAG
CAGGGAGGGGGCTACAACTGGCAGCAGACACAGTCCAAGCCACAGTCCAGCATGCCCCAC
TCCTCTCCCCAGAACCGGCCCAACTACAACGTGAGCTTCTCATCCATGCCTGGGGGCCAG
AACGAACGTGGGAAAGCAGCAGCTAATTTGGAGGGGAAACAAAAAGCAGCTGACTTTGAA
GACCTGCTCTCTGGTCAAGGTTTTAATGCTCACAAAGACAAAAAGGGACCTCGAACAATA
GCTGAGATGAGAAAGGAGGAAATGGCTAAGGAGATGGATCCTGAGAAGTTAAAGATTCTA
GAATGGATTGAAGGCAAAGAGAGGAATATCAGAGCCCTTCTGTCCACAATGCACACTGTG
CTGTGGGCTGGGGAGACTAAGTGGAAACCTGTTGGCATGGCAGACCTGGTCACCCCGGAG
CAGGTGAAGAAGGTGTACAGGAAGGCTGTGCTAGTGGTGCACCCGGATAAAGCTACTGGG
CAACCCTATGAACAATATGCAAAGATGATTTTCATGGAGCTCAATGATGCCTGGTCAGAA
TTTGAAAATCAAGGCCAAAAGCCCTTGTATTAA
Enzyme 56 GenBank Gene ID U09237 Link Image
Enzyme 56 GeneCard ID DNAJC6 Link Image
Enzyme 56 GenAtlas ID Not Available
Enzyme 56 HGNC ID Not Available
Enzyme 56 Chromosome Location Chromosome:1
Enzyme 56 Locus 1pter-q31.3
Enzyme 56 SNPs SNPJam Report Link Image
Enzyme 56 General References
  1. [PubMed Link Image]
Enzyme 56 Metabolite References Not Available
Enzyme 57 [top]
Enzyme 57 ID 191
Enzyme 57 Name ATP10D protein
Enzyme 57 Synonyms Not Available
Enzyme 57 Gene Name ATP10D
Enzyme 57 Protein Sequence >ATP10D protein
MTELLQWARYHWQRPIGRTNTDDDERPYSYSSLLACGGKSSQTPRLAGKHRVVVPHLQLF
KEEYEKFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRVANLYFLFLVVLNWVPLVEAFQK
EITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLVTKVYSRKEKKYVDRCWKDVTVGDF
IHLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQKQVVRRYAEQDSEVDPEKFS
SRIECESPNNDLNRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVMGIVVYAGHETKA
MLNNSGPRYKRSKLERRANTDVLWCVLLLVVMCLTGALGHGIWLSRYENIPFFNIPEPDG
HSLSPVLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQVYFIQSDVDFYNEKMGSTVQC
RALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAASEDE
DSADTPSGSLSNMAKPRALSCRTVHSRPLGSISSNHLTGSCFALESREGASEVPHSRQAA
FSSPIETDVVPDTRLLDKFSQITPLLFTPTDETIPDPPLETLYIIDFFIALAICNTVVVS
APNQPRQKVGLSSLRGIPIKSLEEIKNLFQRLSVRRSSSPSLASGKEPSGVPNAFVSRLS
LFNRMKPASPVEEEISQTSESLQGSDDSACPTEIEKQNSDAGIANGKVEALPGQPLTSSL
CYEAESPDEAALVYAARAYQCTLQSRTPEQVVVDFAALGPLTFQLLHILPFDSVRKRMSV
VVRHPLSNQVVVYTKGADSAIMELLSVASPDGPGLEKQQMMIREKTQKHLDDYAKRGLRT
LCIAKRVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEG
VPEAIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPNDKLFVLNTESKNACEMLMDTI
LKELQKNPASPEQASLSASLHQPPPTLQGSGLRAALIITGKTLEFALQESLQKQFLELTA
RCQAVVCCRATPLQKSEVVKLVRSHLRVMTLAIGDGANDVSMIQVADIGIGISGQEGMQA
VMASDFAVSQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTS
MTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQRSEAYLPLTFWITLL
DAFYQSLVCFFVPYYTYQGSDIDIFTFGNPLNTAALFVILLHLVIESKSLTWIHMLVIAG
SILCYFCFALAFGAMCVTCNPPSNPYWIMQEHMADPVFYLVCVLTTCVALLPRFIYRVLQ
GSLFPSPILRAKHLDRLPAEERIEALKKWRGTGQMDQLTSKYADHSAVESERIPIYDPSA
VFAVMSATACAVEKGNLPVCETALDSDFSETKASGMAGPSKD
Enzyme 57 Number of Residues 1422
Enzyme 57 Molecular Weight 159523.9
Enzyme 57 Theoretical pI 6.21
Enzyme 57 GO Classification
Function
Process
Component
Enzyme 57 General Function Inorganic ion transport and metabolism
Enzyme 57 Specific Function ATP + H(2)O + phospholipid(In) = ADP + phosphate + phospholipid(Out)
Enzyme 57 Pathways Not Available
Enzyme 57 Reactions Not Available
Enzyme 57 Pfam Domain Function
Enzyme 57 Signals
  • None
Enzyme 57 Transmembrane Regions
  • None
Enzyme 57 Essentiality Not Available
Enzyme 57 GenBank ID Protein 157279084 Link Image
Enzyme 57 UniProtKB/Swiss-Prot ID A7Z029 Link Image
Enzyme 57 UniProtKB/Swiss-Prot Entry Name A7Z029_BOVIN Link Image
Enzyme 57 PDB ID Not Available
Enzyme 57 Cellular Location Not Available
Enzyme 57 Gene Sequence >4269 bp
ATGACCGAGCTTCTTCAATGGGCCAGGTATCACTGGCAGCGGCCGATTGGCCGTACGAAC
ACAGACGATGACGAGAGACCATACAGCTATTCCTCTCTGCTTGCCTGCGGGGGCAAGTCC
TCCCAGACCCCCAGACTGGCAGGAAAGCATCGGGTTGTCGTTCCCCACCTCCAGCTCTTC
AAGGAGGAGTATGAAAAGTTCTCTGGAACCTACGTGAATAACAGAATACGGACAACAAAG
TACACGCTGTTGAATTTTGTGCCAAGAAATTTGTTTGAACAATTTCACAGAGTCGCCAAT
TTATATTTCCTGTTTCTAGTTGTTCTGAACTGGGTGCCTTTGGTAGAAGCCTTCCAAAAG
GAAATTACTATGCTGCCTCTGGTGGTTGTCCTTACAATTATTGCAATTAAAGATGGCTTG
GAAGATTACCGAAAATACAAAATTGACAAACAGATCAACAACCTAGTAACTAAAGTTTAT
AGTAGGAAAGAGAAAAAATATGTGGACAGATGCTGGAAAGATGTTACTGTTGGGGACTTT
ATTCACCTTTCCTGTAATGAGGTCATTCCTGCAGATATGGTTTTACTCTTTTCCACTGAT
CCAGATGGAATCTGTCACATTGAGACTTCTGGTCTTGATGGAGAGAGCAATTTAAAACAG
AAGCAGGTGGTTCGGAGATATGCAGAGCAGGACTCTGAAGTTGATCCTGAGAAATTCTCC
AGTAGGATAGAATGTGAAAGTCCAAACAATGACCTCAACAGATTCCGAGGCTTCCTAGAA
CATTCCAACAAAGAACGCGTGGGTCTCAGTAAAGAGAATTTATTGCTTAGAGGATGCACC
ATTAGAAACACAGAGGCTGTCATGGGCATTGTGGTTTATGCAGGCCATGAAACCAAAGCA
ATGCTGAACAACAGCGGACCAAGATACAAGCGCAGCAAATTAGAAAGAAGAGCAAATACA
GATGTCCTCTGGTGTGTCCTACTTTTGGTCGTAATGTGTTTAACTGGTGCATTGGGTCAT
GGAATCTGGTTGAGCAGATATGAAAACATACCCTTTTTTAATATCCCTGAGCCAGATGGA
CATAGCTTATCACCAGTGTTGGCAGGTTTCTATATGTTTTGGACCATGATCATTTTGTTA
CAGGTCTTGATTCCCATTTCTCTCTATGTTTCCATTGAAATTGTGAAGCTTGGACAGGTA
TATTTTATTCAAAGTGATGTGGATTTCTACAATGAGAAAATGGGTTCTACTGTTCAGTGC
CGAGCCCTGAACATCACTGAGGATCTTGGACAGATTCAGTACCTCTTTTCTGATAAAACA
GGAACCCTCACTGAGAATAAGATGGTTTTTCGAAGATGTAGTGTGGCAGGCTTTGATTAC
TGCCATGAAGAAAATGCCAAGAGGTTGGAATCCTATCAGGAAGCTGCCTCTGAAGATGAA
GATTCCGCCGACACTCCCAGTGGCTCCCTCAGCAATATGGCGAAACCGAGGGCCCTCAGC
TGCAGGACAGTTCACAGTCGGCCTTTAGGAAGTATCTCCTCGAATCATCTTACTGGGAGC
TGTTTCGCTCTAGAAAGTAGAGAAGGAGCCAGTGAAGTGCCTCATTCCAGACAGGCTGCT
TTCAGTAGCCCCATTGAAACAGATGTGGTACCAGACACCAGGCTTTTGGACAAGTTTAGT
CAGATTACACCTCTGCTCTTCACCCCAACGGATGAGACTATCCCAGATCCACCACTGGAG
ACTCTGTACATCATCGACTTCTTTATTGCATTGGCAATTTGCAACACAGTAGTGGTTTCT
GCTCCTAACCAGCCACGGCAAAAGGTCGGACTCTCTTCTCTGCGTGGAATACCCATTAAA
TCTTTGGAAGAGATTAAAAACCTCTTCCAGAGACTGTCTGTCCGAAGGTCGAGTTCACCA
TCTCTTGCCAGTGGGAAAGAGCCATCTGGAGTCCCAAACGCCTTTGTGAGCAGACTCTCT
CTGTTTAATAGAATGAAACCAGCCTCACCTGTGGAGGAAGAGATCTCCCAGACGAGTGAG
AGCCTCCAGGGCTCTGATGACTCAGCTTGTCCCACAGAAATTGAGAAACAAAACAGCGAT
GCAGGCATCGCAAATGGCAAGGTGGAAGCCCTCCCTGGACAGCCCTTGACCTCCAGCCTG
TGTTATGAGGCTGAGAGCCCCGATGAAGCTGCCTTAGTGTATGCTGCCCGGGCTTACCAG
TGCACTCTGCAGTCCCGGACCCCAGAGCAGGTCGTGGTGGACTTTGCCGCTTTGGGACCA
TTAACATTTCAACTCCTACACATCCTGCCCTTTGACTCAGTAAGAAAAAGAATGTCCGTG
GTGGTCCGGCACCCCCTTTCCAACCAAGTGGTGGTATATACAAAGGGTGCTGATTCTGCA
ATCATGGAGTTGCTCTCTGTGGCCTCCCCAGATGGACCAGGTCTGGAAAAACAGCAGATG
ATGATAAGGGAGAAAACCCAGAAGCACTTGGATGACTACGCCAAACGAGGCCTGCGCACT
CTGTGTATAGCGAAGAGGGTCATGAGTGACACTGAATATGCAGAGTGGCTGAGAAATCAT
TTTTTAGCTGAAACCAGCATTGACAACAGGGAAGAATTACTCCTTGAATCTGCCATGAGG
TTGGAGAATAAACTAACTTTACTTGGTGCTACTGGCATTGAAGATCGTCTGCAGGAGGGG
GTCCCTGAGGCTATAGAAGCCCTTCACAAAGCTGGAATCAAGATCTGGATGCTGACAGGG
GACAAACAGGAGACAGCTGTCAACATTGCTTATGCGTGCAAACTACTGGAGCCGAATGAC
AAGCTCTTCGTCCTCAATACTGAAAGTAAAAATGCCTGTGAGATGCTGATGGATACAATT
TTGAAAGAACTTCAGAAGAACCCAGCTTCTCCAGAGCAAGCATCGTTGAGTGCGAGTTTA
CACCAGCCTCCTCCCACCCTGCAGGGCTCAGGGCTTCGGGCTGCACTCATTATCACAGGG
AAGACCCTGGAGTTTGCCCTGCAGGAGAGTCTGCAGAAGCAGTTCCTGGAGCTGACTGCT
CGCTGCCAAGCTGTGGTCTGCTGCCGAGCTACGCCCCTGCAGAAGAGCGAGGTGGTAAAA
CTGGTTCGAAGCCACCTCCGGGTGATGACCCTGGCCATCGGTGACGGTGCCAACGATGTC
AGCATGATTCAAGTGGCAGACATTGGCATTGGCATCTCTGGGCAAGAAGGCATGCAGGCT
GTGATGGCCAGCGACTTTGCTGTTTCTCAGTTTAGACATCTCAGCAAGCTCCTCCTTGTC
CACGGGCACTGGTGTTATACCCGACTTTCCAACATGATTCTGTATTTTTTCTACAAGAAC
GTGGCCTACGTGAACCTCCTTTTCTGGTACCAGTTCTTTTGTGGGTTTTCAGGAACATCC
ATGACTGACTACTGGGTTTTGATCTTCTTCAACCTCCTTTTCACATCTGCACCTCCCGTC
ATTTATGGAGTCCTGGAGAAAGACGTGTCTGCAGAGACTCTCATGCAGCTGCCCGAGCTC
TACAGGAGTGGCCAGAGGTCAGAGGCATACTTACCCCTCACCTTCTGGATCACTTTGTTG
GACGCCTTTTATCAGAGCCTGGTCTGCTTCTTCGTGCCTTACTATACCTACCAGGGCTCA
GACATTGACATCTTTACATTTGGAAACCCCCTGAACACAGCTGCTCTGTTCGTCATTCTC
CTCCATCTGGTGATAGAAAGCAAGAGTTTGACTTGGATCCACATGCTGGTCATCGCTGGG
AGCATCTTGTGCTATTTTTGCTTTGCCTTGGCTTTTGGAGCCATGTGTGTGACTTGCAAC
CCACCGTCCAACCCCTACTGGATTATGCAGGAGCACATGGCAGATCCAGTGTTCTACTTG
GTTTGTGTTCTCACAACCTGTGTTGCTCTACTGCCCAGGTTTATATACAGAGTTCTTCAG
GGATCCCTCTTTCCATCTCCAATTCTGAGGGCAAAACACTTGGACAGACTTCCTGCAGAG
GAGAGGATTGAAGCTCTCAAGAAGTGGAGAGGGACTGGGCAGATGGATCAGTTGACATCT
AAGTATGCTGACCACTCAGCTGTTGAGTCAGAGAGAATACCCATTTATGACCCGTCTGCT
GTCTTTGCAGTGATGTCGGCAACTGCTTGTGCTGTTGAGAAAGGAAACTTACCTGTATGT
GAAACTGCTTTAGACTCGGACTTCTCTGAAACTAAGGCCTCAGGGATGGCTGGACCCTCA
AAGGATTAA
Enzyme 57 GenBank Gene ID BC153227 Link Image
Enzyme 57 GeneCard ID ATP10D Link Image
Enzyme 57 GenAtlas ID Not Available
Enzyme 57 HGNC ID Not Available
Enzyme 57 Chromosome Location Chromosome:4
Enzyme 57 Locus 4p12
Enzyme 57 SNPs SNPJam Report Link Image
Enzyme 57 General References Not Available
Enzyme 57 Metabolite References Not Available
Enzyme 58 [top]
Enzyme 58 ID 192
Enzyme 58 Name Acylphosphatase-2
Enzyme 58 Synonyms
  1. Acylphosphate phosphohydrolase 2
  2. Acylphosphatase, muscle type isozyme
Enzyme 58 Gene Name ACYP2
Enzyme 58 Protein Sequence >Acylphosphatase-2
MSTGRPLKSVDYEVFGRVQGVCFRMYTEDEARKIGVVGWVKNTSKGTVTGQVQGPEEKVN
SMKSWLSKVGSPSSRIDRTNFSNEKTISKLEYSSFNIRY
Enzyme 58 Number of Residues 99
Enzyme 58 Molecular Weight 11177.6
Enzyme 58 Theoretical pI 10.20
Enzyme 58 GO Classification
Function
Process
Component
Enzyme 58 General Function Energy production and conversion
Enzyme 58 Specific Function Its physiological role is not yet clear
Enzyme 58 Pathways Not Available
Enzyme 58 Reactions Not Available
Enzyme 58 Pfam Domain Function
Enzyme 58 Signals
  • None
Enzyme 58 Transmembrane Regions
  • None
Enzyme 58 Essentiality Not Available
Enzyme 58 GenBank ID Protein Not Available
Enzyme 58 UniProtKB/Swiss-Prot ID P07033 Link Image
Enzyme 58 UniProtKB/Swiss-Prot Entry Name ACYP2_BOVIN Link Image
Enzyme 58 PDB ID 1APS Link Image
Enzyme 58 PDB File Show
Enzyme 58 3D Structure
Enzyme 58 Cellular Location Not Available
Enzyme 58 Gene Sequence Not Available
Enzyme 58 GenBank Gene ID Not Available
Enzyme 58 GeneCard ID ACYP2 Link Image
Enzyme 58 GenAtlas ID Not Available
Enzyme 58 HGNC ID Not Available
Enzyme 58 Chromosome Location Chromosome:2
Enzyme 58 Locus 2p16.2
Enzyme 58 SNPs SNPJam Report Link Image
Enzyme 58 General References
  1. [PubMed Link Image]
Enzyme 58 Metabolite References Not Available
Enzyme 59 [top]
Enzyme 59 ID 193
Enzyme 59 Name 2',3'-cyclic-nucleotide 3'-phosphodiesterase
Enzyme 59 Synonyms
  1. CNPase
  2. CNP
Enzyme 59 Gene Name CNP
Enzyme 59 Protein Sequence >2',3'-cyclic-nucleotide 3'-phosphodiesterase
MSSSGAKDKPELQFPFLQDEETVATLQECKTLFILRGLPGSGKSTLARFIVDKYRDGTKM
VSADSYKITPGARGSFSEEYKQLDEDLAACCRRDFRVLVLDDTNHERERLEQLFELADQY
QYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLKPGLEKDFLPLYFGWFLTKKSSAA
LWKTGQTFLEELGNHKAFKKELRHFVSGDEPREKIELVTYFGKRPPGVLHCTTKFCDYGK
AAGAEEYAQQDVVKKSYCKAFTLTISALFVTPKTTGARVELSEQQLALWPNDVDKLSPSD
NLPRGSRAHITLGCAGDVEAVQTGIDLLEIVRQEKGGSRGEEVGELSRGKLYSLGSGRWM
LSLAKKMEVRAIFTGYYGKGKAVPIRSGRKGGSFQSCTII
Enzyme 59 Number of Residues 400
Enzyme 59 Molecular Weight 44874.9
Enzyme 59 Theoretical pI 8.58
Enzyme 59 GO Classification
Function
Process
Component
Enzyme 59 General Function Involved in 2',3'-cyclic-nucleotide 3'-phosphodiesteras
Enzyme 59 Specific Function Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 2'-phosphate
Enzyme 59 Pathways Not Available
Enzyme 59 Reactions Not Available
Enzyme 59 Pfam Domain Function
Enzyme 59 Signals
  • None
Enzyme 59 Transmembrane Regions
  • None
Enzyme 59 Essentiality Not Available
Enzyme 59 GenBank ID Protein 262 Link Image
Enzyme 59 UniProtKB/Swiss-Prot ID P06623 Link Image
Enzyme 59 UniProtKB/Swiss-Prot Entry Name CN37_BOVIN Link Image
Enzyme 59 PDB ID Not Available
Enzyme 59 Cellular Location Not Available
Enzyme 59 Gene Sequence >1203 bp
ATGTCATCCTCAGGGGCCAAGGACAAGCCGGAGCTGCAGTTTCCCTTCCTGCAGGATGAG
GAGACGGTGGCCACGCTGCAGGAGTGCAAGACGCTCTTCATCCTGCGAGGCCTGCCTGGG
AGCGGCAAGTCCACGCTGGCCCGGTTCATCGTGGACAAGTACCGGGATGGCACCAAGATG
GTGTCTGCCGACAGCTACAAGATCACCCCTGGCGCCCGGGGATCCTTCTCTGAGGAGTAC
AAGCAGCTGGACGAGGACCTGGCTGCCTGTTGCCGCCGGGATTTCCGGGTCCTGGTGCTG
GATGATACCAACCATGAGCGGGAGCGGCTGGAGCAGCTCTTTGAGCTGGCCGACCAGTAC
CAGTACCAGGTGGTGCTGGTGGAGCCCAAGACGGCCTGGCGGCTGGACTGTGCCCAGCTC
AAGGAGAAGAACCAGTGGCAGCTGTCAGCAGATGATCTGAAGAAGCTGAAGCCTGGGCTG
GAGAAGGACTTCCTGCCGCTTTACTTCGGCTGGTTCCTGACCAAGAAGAGTTCCGCGGCC
CTCTGGAAAACTGGCCAGACCTTCCTGGAGGAGCTGGGCAATCACAAGGCCTTCAAGAAG
GAGCTGCGACACTTTGTCTCTGGGGATGAGCCCAGGGAGAAGATTGAACTGGTCACCTAC
TTCGGGAAGAGACCGCCGGGCGTGCTGCATTGCACAACCAAGTTCTGTGACTACGGGAAG
GCCGCTGGGGCAGAGGAGTATGCCCAGCAAGATGTAGTGAAGAAATCCTACTGCAAGGCC
TTCACGCTGACCATCTCGGCCCTCTTCGTGACACCCAAGACGACGGGAGCCAGAGTAGAG
CTGAGCGAGCAGCAGCTGGCCTTGTGGCCAAACGACGTGGACAAGCTGTCTCCCTCTGAC
AACCTGCCACGGGGCAGCCGCGCACACATCACCTTGGGCTGCGCGGGTGACGTAGAGGCC
GTGCAGACAGGCATCGACCTGCTAGAGATTGTGCGGCAGGAGAAGGGGGGCAGCCGCGGC
GAGGAGGTGGGTGAGCTCAGCCGGGGCAAGCTCTACTCCCTGGGCAGCGGGCGCTGGATG
CTGAGCCTGGCCAAGAAGATGGAGGTCAGGGCTATCTTTACAGGATACTACGGGAAGGGC
AAGGCCGTGCCCATACGCAGCGGCCGCAAGGGTGGCTCCTTTCAGTCCTGTACCATCATC
TGA
Enzyme 59 GenBank Gene ID Y00405 Link Image
Enzyme 59 GeneCard ID CNP Link Image
Enzyme 59 GenAtlas ID Not Available
Enzyme 59 HGNC ID Not Available
Enzyme 59 Chromosome Location Chromosome:1
Enzyme 59 Locus 17q21
Enzyme 59 SNPs SNPJam Report Link Image
Enzyme 59 General References
  1. [PubMed Link Image]
Enzyme 59 Metabolite References Not Available
Enzyme 60 [top]
Enzyme 60 ID 194
Enzyme 60 Name Eyes absent homolog 2
Enzyme 60 Synonyms Not Available
Enzyme 60 Gene Name EYA2
Enzyme 60 Protein Sequence >Eyes absent homolog 2
MLELLVSASLTVNSDRPGKLKPSRADADVWTLSDREGITTSARSVSQLFARPCPRVPPGQ
PPSAMAAYSQTQYSAGIQQATPYTAYPPPAQAYGIPSYSIKTEDSLNHSPGQSGFLSYGS
SFSTPASGQSPYTYQMHGTAGIYQGANGLTNAAGFGTVHQDYPSYPGFPQSQYSQYYSSS
YNPPYVPASSICPSPLSTSTYVLQEASHNIPSQSSESLGGEYNTHNGPSTPAKEGDTDRP
PRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTAS
VRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPG
ANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGAPKRETWLQLRAELEALT
DLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKE
SCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
Enzyme 60 Number of Residues 537
Enzyme 60 Molecular Weight 58806.0
Enzyme 60 Theoretical pI 6.15
Enzyme 60 GO Classification
Function
Process
Component
Enzyme 60 General Function Involved in magnesium ion binding
Enzyme 60 Specific Function Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1. Seems to coactivate SIX2, SIX4 and SIX5. Together with SIX1 and DACH2 seem to be involved in myogenesis. May be involved in development of the eye. Interaction with GNAZ and GNAI2 prevents nuclear translocation and transcriptional activity
Enzyme 60 Pathways Not Available
Enzyme 60 Reactions Not Available
Enzyme 60 Pfam Domain Function
Enzyme 60 Signals
  • None
Enzyme 60 Transmembrane Regions
  • None
Enzyme 60 Essentiality Not Available
Enzyme 60 GenBank ID Protein 61554261 Link Image
Enzyme 60 UniProtKB/Swiss-Prot ID Q58DB6 Link Image
Enzyme 60 UniProtKB/Swiss-Prot Entry Name EYA2_BOVIN Link Image
Enzyme 60 PDB ID Not Available
Enzyme 60 Cellular Location Not Available
Enzyme 60 Gene Sequence >1614 bp
ATGCTAGAACTACTGGTCTCAGCCAGCCTTACTGTAAACAGTGATCGTCCGGGTAAACTG
AAGCCTAGCCGTGCTGATGCTGATGTCTGGACTCTGAGTGACAGAGAAGGCATCACCACA
TCGGCTCGGAGTGTGTCCCAGCTCTTTGCAAGACCTTGCCCGCGTGTCCCACCTGGTCAG
CCTCCCTCGGCCATGGCAGCCTACAGCCAGACACAGTACAGTGCAGGGATCCAGCAAGCT
ACCCCCTACACGGCTTACCCGCCTCCAGCACAAGCCTATGGAATCCCTTCTTACAGCATC
AAGACAGAAGACAGCTTGAACCATTCCCCCGGCCAGAGTGGCTTCCTCAGCTATGGCTCC
AGCTTCAGCACCCCAGCCTCTGGACAGAGCCCGTACACCTACCAGATGCATGGCACGGCC
GGGATCTATCAAGGAGCAAATGGACTGACCAACGCGGCCGGATTCGGAACTGTGCACCAG
GACTATCCTTCCTACCCCGGCTTCCCGCAGAGCCAGTACTCCCAGTATTACAGCTCGTCC
TACAACCCTCCTTACGTCCCAGCCAGCAGCATCTGCCCTTCTCCTCTCTCCACGTCCACC
TACGTCCTCCAAGAGGCATCTCACAACATCCCCAGCCAGAGTTCCGAGTCGCTTGGCGGT
GAATATAACACACACAATGGACCTTCCACACCGGCAAAGGAGGGAGACACAGACAGGCCA
CCCCGGGCCTCCGACGGGAAGCTCCGAGGCCGGTCTAAGCGGAGCAGCGACCCCTCCCCA
GCAGGGGACAATGAGATCGAGCGTGTGTTCGTGTGGGACCTGGATGAGACGATAATTATT
TTCCACTCCTTACTCACGGGGACTTTCGCCTCCAGGTACGGGAAGGACACCACGGCGTCC
GTGCGCATCGGCCTCATGATGGAGGAAATGATCTTCAACCTCGCAGACACACATCTGTTC
TTCAATGACCTGGAGGATTGTGACCAGATCCACGTGGACGATGTCTCATCTGATGACAAT
GGGCAAGATTTAAGCACCTACAACTTCTCCGCCGATGGCTTCCACAGTTCGGCCCCGGGA
GCCAACCTGTGCCTGGGCTCCGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCC
TTCCGCTACCGGCGGGTGAAGGAGATGTACAACACCTACAAGAACAACGTCGGCGGCTTG
ATAGGAGCTCCCAAAAGAGAGACCTGGCTACAGCTCAGAGCCGAGCTGGAAGCTCTGACT
GACCTCTGGCTGACCCACTCTCTGAAGGCACTAAACCTCATCAATTCCCGGCCCAATTGT
GTCAACGTGCTGGTCACCACCACTCAACTAATTCCTGCCCTGGCCAAAGTCCTGCTGTAC
GGATTGGGTTCTGTGTTTCCTATTGAGAACATCTACAGTGCAACCAAGACAGGGAAGGAG
AGCTGCTTCGAGAGGATAATGCAGAGGTTTGGCAGAAAGGCCGTCTACATCGTGATCGGC
GATGGAGTGGAAGAGGAGCAGGGAGCCAAAAAGCACAACATGCCTTTCTGGAGGATATCC
TGCCACGCAGACCTGGAGGCGCTGAGGCACGCCCTGGAGCTGGAGTATTTATAG
Enzyme 60 GenBank Gene ID BT021681 Link Image
Enzyme 60 GeneCard ID EYA2 Link Image
Enzyme 60 GenAtlas ID Not Available
Enzyme 60 HGNC ID Not Available
Enzyme 60 Chromosome Location Chromosome:2
Enzyme 60 Locus 20q13.1
Enzyme 60 SNPs SNPJam Report Link Image
Enzyme 60 General References
  1. [PubMed Link Image]
Enzyme 60 Metabolite References Not Available
Enzyme 61 [top]
Enzyme 61 ID 195
Enzyme 61 Name 3'(2'),5'-bisphosphate nucleotidase 1
Enzyme 61 Synonyms
  1. Bisphosphate 3'-nucleotidase 1
Enzyme 61 Gene Name BPNT1
Enzyme 61 Protein Sequence >3'(2'),5'-bisphosphate nucleotidase 1
MASSPTVLMRLVASAYSIAQKAGTIVRRVIAEGDLGIIEKTCATDLQTKADRLVQVSICS
SLARKFPKLTIIGEEDLPPEDVDQELIEDGQWEEILKQPCPSQYSAIKEEDLVVWVDPLD
GTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYQAGPDAVLGRTIWGVLGLGAFGF
QLKEAPAGKHIITTTRSHNSQLVTDCITAMNPDDVLRVGGAGNKIIQLIEGKASAYVFAS
PGCKKWDTCAPEVILHAVGGKLTDIHGNALQYNKEVKHMNSAGVLATLRNYDYYASRVPQ
SVKNALVP
Enzyme 61 Number of Residues 308
Enzyme 61 Molecular Weight 33327.9
Enzyme 61 Theoretical pI 5.19
Enzyme 61 GO Classification
Function
Process
Component
Enzyme 61 General Function Carbohydrate transport and metabolism
Enzyme 61 Specific Function Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4- trisphosphate (Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6
Enzyme 61 Pathways Not Available
Enzyme 61 Reactions Not Available
Enzyme 61 Pfam Domain Function
Enzyme 61 Signals
  • None
Enzyme 61 Transmembrane Regions
  • None
Enzyme 61 Essentiality Not Available
Enzyme 61 GenBank ID Protein 152941250 Link Image
Enzyme 61 UniProtKB/Swiss-Prot ID Q3ZCK3 Link Image
Enzyme 61 UniProtKB/Swiss-Prot Entry Name BPNT1_BOVIN Link Image
Enzyme 61 PDB ID 1JP4 Link Image
Enzyme 61 PDB File Show
Enzyme 61 3D Structure
Enzyme 61 Cellular Location Not Available
Enzyme 61 Gene Sequence >927 bp
ATGGCATCCAGTCCCACTGTGTTGATGCGGTTGGTGGCTTCAGCATATTCTATTGCTCAA
AAGGCAGGAACGATAGTCAGGCGTGTTATCGCCGAAGGAGACCTGGGTATCATTGAGAAG
ACCTGTGCAACAGACCTGCAGACCAAGGCTGACCGATTAGTTCAAGTGAGCATATGTTCT
TCATTGGCACGGAAGTTCCCCAAACTAACAATTATAGGGGAAGAGGATCTGCCTCCTGAA
GACGTGGATCAAGAGCTGATTGAAGATGGTCAGTGGGAGGAGATACTGAAGCAGCCGTGC
CCATCACAGTACAGTGCTATCAAGGAGGAAGATCTTGTGGTCTGGGTTGATCCTCTGGAT
GGGACCAAGGAATATACTGAAGGTCTTCTTGACAATGTAACAGTACTTATTGGAATTGCT
TATGAAGGAAAAGCCATAGCAGGAGTTATTAACCAGCCATATTACAACTACCAGGCAGGA
CCAGATGCTGTGCTGGGGAGAACTATCTGGGGAGTTTTGGGTTTAGGTGCCTTCGGGTTT
CAGCTGAAAGAAGCGCCCGCCGGCAAACACATCATCACAACAACCCGGTCCCATAACAGC
CAGTTGGTTACGGACTGCATCACTGCTATGAACCCTGATGATGTGCTGAGAGTGGGAGGA
GCAGGAAATAAGATAATTCAGCTGATTGAAGGCAAAGCCTCTGCTTATGTATTTGCAAGT
CCAGGATGCAAGAAGTGGGACACCTGTGCTCCAGAAGTCATTTTACATGCTGTCGGAGGC
AAGTTAACCGATATCCATGGAAATGCTCTTCAGTATAACAAGGAAGTGAAGCACATGAAC
TCGGCCGGAGTCCTGGCCACACTGAGGAATTATGACTATTATGCAAGTCGAGTCCCCCAG
TCTGTTAAAAATGCCCTTGTTCCTTGA
Enzyme 61 GenBank Gene ID BT030746 Link Image
Enzyme 61 GeneCard ID BPNT1 Link Image
Enzyme 61 GenAtlas ID Not Available
Enzyme 61 HGNC ID Not Available
Enzyme 61 Chromosome Location Chromosome:1
Enzyme 61 Locus 1q41
Enzyme 61 SNPs SNPJam Report Link Image
Enzyme 61 General References
  1. [PubMed Link Image]
Enzyme 61 Metabolite References Not Available
Enzyme 62 [top]
Enzyme 62 ID 196
Enzyme 62 Name Probable phospholipid-transporting ATPase IA
Enzyme 62 Synonyms
  1. Chromaffin granule ATPase II
  2. ATPase class I type 8A member 1
Enzyme 62 Gene Name ATP8A1
Enzyme 62 Protein Sequence >Probable phospholipid-transporting ATPase IA
MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEIRTIFINQPQLTKFCNNHVSTAKYN
IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED
IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAM
CYIETSNLDGETNLKIRQGLPATSDIKDIDSLMRLSGRIECESPNRHLYDFVGNIRLDGR
STVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI
LFCILIAMSLVCSVGSAIWNRRHSGRDWYLNLNYGGANNFGLNFLTFIILFNNLIPISLL
VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNVELGQVKYIFSDKTGTLTCNVMQ
FKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPERE
GDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKR
MSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEIS
ESDFQEWRAVYHRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLM
KADIKIWILTGDKQETAINIGHSCKLRRKNMGMIVINEGSLDGTRETLSRHCTTLGDALR
KENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVI
TLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMVHGAWNYNRG
SKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSC
RKEYMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTVFENGRTS
DYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAVPMA
PDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKSQDPG
AVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQDENGIVSQSEVIRAYD
TTKQRPDEW
Enzyme 62 Number of Residues 1149
Enzyme 62 Molecular Weight 130024.9
Enzyme 62 Theoretical pI 7.58
Enzyme 62 GO Classification
Function
Process
Component
Enzyme 62 General Function Inorganic ion transport and metabolism
Enzyme 62 Specific Function May play a role in the transport of aminophospholipids from the outer to the inner leaflet of various membranes and the maintenance of asymmetric distribution of phospholipids, mainly in secretory vesicles
Enzyme 62 Pathways Not Available
Enzyme 62 Reactions Not Available
Enzyme 62 Pfam Domain Function
Enzyme 62 Signals
  • None
Enzyme 62 Transmembrane Regions
  • 66-86 93-115 298-319 345-366 843-863 876-895 926-947 962-984 991-1011 1030-1055
Enzyme 62 Essentiality Not Available
Enzyme 62 GenBank ID Protein 4115341 Link Image
Enzyme 62 UniProtKB/Swiss-Prot ID Q29449 Link Image
Enzyme 62 UniProtKB/Swiss-Prot Entry Name AT8A1_BOVIN Link Image
Enzyme 62 PDB ID Not Available
Enzyme 62 Cellular Location Not Available
Enzyme 62 Gene Sequence >3450 bp
ATGCCCACCATGCGGAGGACCGTGTCGGAGATCCGGTCCCGAGCCGAGGGTTATGAGAAG
ACTGATGATGTTTCAGAGAAGACGTCACTGGCTGACCAGGAAGAAATAAGGACTATATTC
ATCAACCAGCCTCAGCTGACAAAATTCTGCAATAACCATGTCAGCACTGCAAAATACAAC
ATAATCACATTCCTTCCAAGATTTCTCTACTCTCAGTTCAGAAGAGCCGCTAATTCATTT
TTTCTCTTTATTGCACTGCTCCAGCAAATACCTGATGTATCACCAACAGGTCGCTATACA
ACACTGGTTCCTCTCTTATTTATTTTGGCTGTGGCAGCTATCAAAGAGATAATAGAAGAT
ATTAAACGACATAAAGCTGATAATGCAGTAAACAAGAAGCAGACACAAGTTTTAAGAAAT
GGTGCTTGGGAAATTGTGCACTGGGAAAAGGTAAATGTTGGAGATATAGTTATAATAAAA
GGCAAAGAGTATATACCTGCTGACACTGTACTTCTCTCATCAAGTGAGCCCCAGGCCATG
TGTTACATTGAAACATCCAACTTAGATGGTGAAACAAACCTGAAAATTAGACAGGGCTTA
CCAGCAACATCAGATATAAAAGACATTGACAGTTTGATGAGACTGTCTGGCAGAATTGAG
TGTGAAAGTCCAAACAGACATCTCTATGATTTTGTTGGAAACATACGGCTTGATGGACGC
AGCACTGTTCCCCTGGGAGCAGACCAGATTCTTCTGCGAGGTGCTCAATTGAGAAATACA
CAGTGGGTTCATGGAATAGTTGTCTACACTGGACATGACACCAAGCTAATGCAGAACTCA
ACAAGTCCACCACTTAAACTCTCAAATGTCGAAAGGATTACAAATGTACAAATTTTGATT
TTATTTTGTATCTTGATTGCCATGTCTCTTGTCTGTTCTGTGGGCTCAGCCATTTGGAAT
CGAAGGCATTCTGGAAGGGACTGGTATCTCAATCTAAACTATGGTGGTGCTAATAATTTT
GGACTGAATTTCTTGACGTTCATCATCCTTTTCAATAACCTCATTCCTATCAGCTTGCTG
GTGACATTAGAAGTGGTGAAATTTACCCAGGCATACTTCATAAATTGGGATCTTGACATG
CACTATGAACCAACTGACACTGCTGCTATGGCTCGAACATCTAATCTGAATGTGGAACTT
GGCCAGGTGAAATATATATTTTCTGACAAAACTGGTACTTTGACATGCAATGTAATGCAG
TTTAAGAAGTGCACCATAGCCGGAGTGGCTTACGGGCAGAACTCACAGTTTGGAGATGAA
AAAACATTTAGTGATTCATCATTGCTGGAAAACCTCCAAAATAATCATCCCACTGCACCA
ATAATATGTGAATTTCTTACAATGATGGCCGTGTGTCACACGGCAGTACCAGAGCGGGAA
GGTGATAAGATAATTTACCAGGCAGCATCTCCAGATGAGGGAGCCTTGGTCAGAGCAGCC
AAGCAGTTGAATTTTGTTTTCACTGGAAGAACGCCTGACTCAGTGATTATAGATTCACTG
GGGCAGGAAGAAAGATATGAATTGCTCAATGTCTTGGAGTTCACCAGCGCTAGAAAAAGA
ATGTCAGTGATCGTTCGCACTCCATCCGGGAAGTTACGACTTTACTGCAAAGGAGCCGAC
ACTGTAATTTATGACCGACTGGCAGAAACTTCAAAATACAAAGAAATTACCCTAAAACAT
TTGGAGCAGTTTGCTACAGAAGGGTTAAGAACCTTGTGTTTTGCCGTGGCTGAGATTTCA
GAGAGCGACTTTCAGGAGTGGCGAGCCGTCTATCACCGTGCCTCCACATCTGTGCAGAAC
AGGCTGCTCAAACTCGAAGAGAGCTACGAGTTAATCGAAAAGAATCTTCAACTACTGGGA
GCCACAGCCATTGAGGATAAATTACAAGATCAAGTGCCTGAAACCATAGAAACTCTAATG
AAAGCAGACATCAAAATCTGGATCCTTACAGGAGACAAGCAGGAAACTGCCATTAACATT
GGGCACTCCTGCAAACTTCGGAGGAAGAACATGGGAATGATTGTTATAAATGAAGGCTCT
CTTGATGGAACACGGGAAACTCTCAGTCGTCACTGCACTACTCTGGGTGATGCTCTTCGG
AAGGAGAATGACTTTGCTCTTATAATTGATGGGAAAACCCTCAAATATGCCTTAACTTTT
GGAGTGAGGCAGTATTTCCTGGACTTAGCTTTGTCGTGCAAAGCTGTTATTTGCTGCAGG
GTTTCTCCTCTTCAAAAATCTGAAGTTGTGGAGATGGTTAAGAAACAAGTTAAAGTCATA
ACACTCGCCATTGGTGATGGAGCAAATGACGTCAGTATGATACAGACGGCACATGTTGGA
GTAGGAATAAGTGGCAATGAAGGCCTTCAGGCAGCTAATTCTTCTGACTACTCTATAGCT
CAGTTCAAATATTTGAAGAATTTGTTGATGGTTCATGGTGCCTGGAACTATAACAGAGGC
TCCAAGTGTATCTTATACTGCTTCTACAAGAATATAGTCCTCTATATTATCGAGATCTGG
TTTGCCTTCGTGAATGGCTTTTCTGGACAGATCCTCTTTGAGAGATGGTGCATAGGTCTT
TATAATGTGATGTTTACAGCAATGCCACCCTTAACTCTGGGAATATTTGAGAGATCATGC
AGAAAGGAGTATATGTTGAAGTATCCTGAATTATACAAAACATCTCAGAATGCCCTGGAC
TTCAACACCAAGGTTTTCTGGGTTCATTGTTTAAATGGCCTCTTCCACTCAGTTATTCTG
TTTTGGTTTCCACTAAAAGCCCTTCAATATGGCACTGTATTTGAAAATGGGAGAACTTCT
GATTACCTGCTGTTGGGAAACTTCGTTTACACATTTGTGGTGATAACTGTGTGCTTGAAA
GCTGGATTGGAGACATCATATTGGACCTGGTTCAGCCACATAGCCATCTGGGGCAGCATC
GCACTCTGGGTGGTGTTTTTTGGAATCTACTCATCTCTGTGGCCTGCTGTTCCAATGGCC
CCTGATATGTCAGGAGAGGCAGCCATGTTGTTCAGTTCTGGAGTCTTTTGGATGGGCCTG
TTATTTATCCCTGTGGCCTCCTTGCTCCTTGATGTGGTGTATAAAGTTATCAAGAGGACT
GCTTTTAAAACATTAGTAGATGAAGTTCAGGAGCTGGAGGCAAAATCTCAAGACCCAGGA
GCAGTTGTGCTTGGAAAAAGCCTCACAGAGAGGGCGCAACTGCTCAAGAACGTCTTTAAG
AAGAACCACGTGAACTTGTACCGGTCAGAATCACTGCAACAAAACCTGCTCCATGGGTAT
GCTTTCTCTCAAGATGAAAATGGAATCGTCTCACAGTCTGAAGTGATTAGAGCATATGAT
ACCACAAAGCAGAGACCTGATGAGTGGTGA
Enzyme 62 GenBank Gene ID U51100 Link Image
Enzyme 62 GeneCard ID ATP8A1 Link Image
Enzyme 62 GenAtlas ID Not Available
Enzyme 62 HGNC ID Not Available
Enzyme 62 Chromosome Location Chromosome:4
Enzyme 62 Locus 4p14-p12
Enzyme 62 SNPs SNPJam Report Link Image
Enzyme 62 General References
  1. [PubMed Link Image]
Enzyme 62 Metabolite References Not Available
Enzyme 63 [top]
Enzyme 63 ID 197
Enzyme 63 Name Glutathione synthetase
Enzyme 63 Synonyms
  1. Glutathione synthase
  2. GSH synthetase
  3. GSH-S
Enzyme 63 Gene Name GSS
Enzyme 63 Protein Sequence >Glutathione synthetase
MATGWGSLLQDEQQLEELARQAVDRALAEGVLLRTSQAPSSSHVVSYAPFTLFPSPVPSA
LLEQAYAVQADFNLLVDAVSQNAVFLEQTLSSTIKRDSFTARLFDIHKQVLKEGIAQTVF
LGLNRSDYMFQCNPDGSAALKQIEINTVSASFGGLASRTPAVHRHVLSVLGKTKEAAKIL
SNNPSKGLAMGIAKAWELYGSANAQVLLIAQEKERNIFDQRAIENELLARNIHVIRRKFE
DVSEKGSLDQDRRLFMDGQEIAVVYFRDGYMPGHYSLQNWEARLLLERSCAVKCPDIATQ
LAGTKKVQQELSRVGVLESFLPGQPEAVARLRATFAGLYSLDLGEEGDQAITKAIAAPSC
FVLKPQREGGGNNLYGEEMVQALERLKDSEERASYILMEKIEPEPFRNCLLRPGSPARVI
QCISELGIFGVYVREGKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV
Enzyme 63 Number of Residues 474
Enzyme 63 Molecular Weight 52065.0
Enzyme 63 Theoretical pI 6.44
Enzyme 63 GO Classification
Function
Process
Component
Enzyme 63 General Function Involved in ATP binding
Enzyme 63 Specific Function ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
Enzyme 63 Pathways
  • Sulfur metabolism
  • glutathione biosynthesis
  • glutathione from L-cysteine and L-glutamate:step 2/2
Enzyme 63 Reactions Not Available
Enzyme 63 Pfam Domain Function
Enzyme 63 Signals
  • None
Enzyme 63 Transmembrane Regions
  • None
Enzyme 63 Essentiality Not Available
Enzyme 63 GenBank ID Protein 59857659 Link Image
Enzyme 63 UniProtKB/Swiss-Prot ID Q5EAC2 Link Image
Enzyme 63 UniProtKB/Swiss-Prot Entry Name GSHB_BOVIN Link Image
Enzyme 63 PDB ID Not Available
Enzyme 63 Cellular Location Not Available
Enzyme 63 Gene Sequence >1425 bp
ATGGCCACCGGCTGGGGGAGCCTCTTGCAGGATGAACAGCAGCTGGAGGAGCTAGCAAGG
CAGGCTGTGGACCGGGCTCTGGCTGAGGGTGTGTTGCTGAGGACCTCACAGGCACCCAGC
TCCTCTCATGTGGTGAGCTATGCTCCATTCACACTCTTCCCTTCACCGGTCCCAAGTGCC
CTGCTGGAGCAGGCCTATGCTGTGCAGGCGGACTTCAACCTCCTGGTGGATGCGGTCAGC
CAAAATGCTGTCTTTCTGGAGCAGACTCTCTCCAGCACCATCAAAAGAGACAGCTTTACT
GCTCGTCTCTTTGACATCCACAAGCAAGTCTTAAAAGAAGGCATTGCCCAGACCGTGTTC
CTGGGCTTGAATCGCTCAGACTACATGTTCCAGTGCAATCCGGATGGCTCCGCAGCCCTG
AAACAGATTGAAATCAACACCGTCTCTGCCAGCTTTGGGGGCCTAGCCTCCCGGACCCCA
GCTGTGCATCGACATGTTCTCAGTGTCCTGGGTAAGACCAAAGAAGCTGCCAAGATCCTC
TCCAATAATCCCAGCAAGGGACTGGCCATGGGGATTGCCAAAGCCTGGGAGCTCTACGGC
TCAGCCAATGCTCAGGTGCTACTGATTGCTCAAGAGAAGGAAAGGAACATATTTGACCAG
CGTGCCATAGAGAATGAGCTACTGGCCAGGAATATCCATGTAATCCGACGAAAGTTCGAA
GATGTCTCTGAAAAGGGGTCTCTAGACCAAGACCGAAGACTATTTATGGACGGCCAGGAG
ATTGCTGTGGTTTACTTCCGGGATGGCTACATGCCAGGCCATTACAGCCTACAGAACTGG
GAAGCACGCCTGCTCCTGGAGAGGTCATGTGCTGTCAAGTGCCCGGATATTGCCACCCAG
CTGGCCGGGACCAAGAAGGTGCAGCAGGAGCTGAGCAGAGTGGGCGTGCTGGAGTCCTTT
CTCCCAGGGCAGCCTGAGGCTGTGGCCCGCCTCCGTGCCACCTTTGCTGGCCTCTACTCA
CTAGACCTGGGTGAAGAAGGGGACCAGGCTATCACCAAGGCCATTGCTGCTCCTAGCTGC
TTTGTGCTAAAGCCTCAAAGAGAGGGTGGAGGTAACAACCTATACGGGGAGGAGATGGTA
CAAGCCCTGGAGCGGCTGAAGGACAGTGAGGAGAGAGCCTCCTACATCCTCATGGAGAAG
ATCGAACCCGAGCCTTTTAGGAATTGTCTACTACGACCCGGCAGCCCTGCCCGAGTGATC
CAATGCATTTCAGAGCTGGGCATCTTCGGGGTCTATGTCAGGGAGGGAAAGACACTTGTG
ATGAACAAGCACGTGGGACATCTGCTTCGAACCAAAGCCATCGAGCATGCAGATGGCGGT
GTGGCGGCTGGAGTGGCAGTCCTGGACAACCCGTACCCTGTGTGA
Enzyme 63 GenBank Gene ID BT020647 Link Image
Enzyme 63 GeneCard ID GSS Link Image
Enzyme 63 GenAtlas ID Not Available
Enzyme 63 HGNC ID Not Available
Enzyme 63 Chromosome Location Chromosome:2
Enzyme 63 Locus 20q11.2
Enzyme 63 SNPs SNPJam Report Link Image
Enzyme 63 General References
  1. [PubMed Link Image]
Enzyme 63 Metabolite References Not Available
Enzyme 64 [top]
Enzyme 64 ID 198
Enzyme 64 Name Alkaline phosphatase
Enzyme 64 Synonyms Not Available
Enzyme 64 Gene Name LOC100125266
Enzyme 64 Protein Sequence >Alkaline phosphatase
MQGACVLLLLGLHLQLSLGLVPVEEEDPAFWNRQAAQALDVAKKLQPIQTAAKNVILFLG
DGMGVPTVTATRILKGQMNGKLGPETPLAMDQFPYVALSKTYNVDRQVPDSAGTATAYLC
GVKGNYRTIGVSAAARYNQCKTTRGNEVTSVMNRAKKAGKSVGVVTTTRVQHASPAGAYA
HTVNRNWYSDADLPADAQMNGCQDIAAQLVNNMDIDVILGGGRKYMFPVGTPDPEYPDDA
SVNGVRKDKQNLVQAWQAKQQGAQYVWNRTALLQAADDSSVTHLMGLFEPADMKYNVQQD
PTKDPTLQEMTEVALRVLSRNPRGFYLFVEGGRIDHGHHDDKAYMALTEAVMFDNAIAKA
NELTSELDTLILVTADHSHVFSFGGYTLRGTSIFGLAPSKALDSKSYTSILYGNGPGYAL
GGGSRPDVNDSTSEDPSYQQQAAVPLASETHGGEDVAVFARGPQAHLVHGVQEETFVAHI
MAFAGCVEPYTDCNLPAPTTATSIPDAAHLAASPPPLALLAGAMLLLLAPTLY
Enzyme 64 Number of Residues 533
Enzyme 64 Molecular Weight 57049.1
Enzyme 64 Theoretical pI 5.71
Enzyme 64 GO Classification
Function
Process
Component
Enzyme 64 General Function Inorganic ion transport and metabolism
Enzyme 64 Specific Function A phosphate monoester + H(2)O = an alcohol + phosphate
Enzyme 64 Pathways Not Available
Enzyme 64 Reactions Not Available
Enzyme 64 Pfam Domain Function
Enzyme 64 Signals
  • None
Enzyme 64 Transmembrane Regions
  • None
Enzyme 64 Essentiality Not Available
Enzyme 64 GenBank ID Protein 151556049 Link Image
Enzyme 64 UniProtKB/Swiss-Prot ID A6QQR9 Link Image
Enzyme 64 UniProtKB/Swiss-Prot Entry Name A6QQR9_BOVIN Link Image
Enzyme 64 PDB ID Not Available
Enzyme 64 Cellular Location Not Available
Enzyme 64 Gene Sequence >1602 bp
ATGCAGGGGGCCTGCGTGCTGCTGCTGCTGGGCCTGCATCTACAGCTCTCCCTAGGCCTC
GTCCCAGTTGAGGAGGAAGACCCCGCCTTCTGGAACCGCCAGGCAGCCCAGGCCCTCGAT
GTGGCTAAGAAGCTGCAGCCCATCCAGACAGCCGCCAAGAATGTCATCCTCTTCTTGGGG
GATGGGATGGGGGTGCCTACGGTGACAGCCACTCGGATCCTAAAGGGGCAGATGAATGGC
AAACTGGGACCTGAGACACCCCTGGCCATGGACCAGTTCCCATACGTGGCTCTGTCCAAG
ACATACAACGTGGACAGACAGGTGCCAGACAGCGCAGGCACTGCCACTGCCTACCTGTGT
GGGGTCAAGGGCAACTACAGAACCATTGGTGTAAGTGCAGCCGCCCGCTACAACCAGTGC
AAAACGACACGTGGGAATGAGGTCACGTCTGTGATGAACCGGGCCAAGAAAGCAGGGAAG
TCCGTGGGAGTGGTGACCACCACCAGGGTGCAGCATGCCTCCCCAGCCGGGGCCTACGCG
CACACGGTGAACCGAAACTGGTACTCAGACGCCGACCTGCCTGCTGATGCACAGATGAAT
GGCTGCCAGGACATCGCCGCACAGCTGGTCAACAACATGGATATTGACGTGATCCTGGGT
GGAGGCCGAAAATACATGTTTCCTGTGGGGACCCCAGACCCTGAATACCCAGATGATGCC
AGTGTGAATGGAGTCCGGAAGGACAAGCAGAACCTGGTGCAGGCATGGCAGGCCAAGCAG
CAGGGAGCCCAGTATGTGTGGAACCGCACTGCGCTCCTTCAGGCGGCCGATGACTCCAGT
GTAACACACCTCATGGGCCTCTTTGAGCCGGCAGACATGAAGTATAATGTTCAGCAAGAC
CCCACCAAGGACCCGACCCTGCAGGAAATGACAGAGGTGGCCCTGCGAGTGCTAAGCAGG
AACCCCAGGGGCTTCTACCTCTTTGTGGAGGGAGGCCGCATTGACCACGGTCACCATGAT
GACAAAGCTTATATGGCACTGACCGAGGCGGTCATGTTTGACAATGCCATCGCCAAGGCT
AATGAGCTCACTAGCGAACTGGACACGCTGATCCTTGTCACTGCAGACCACTCTCATGTC
TTCTCTTTTGGTGGCTATACACTGCGTGGGACCTCCATTTTTGGTCTGGCCCCCAGCAAG
GCCTTAGACAGCAAGTCCTACACCTCCATCCTCTATGGCAATGGCCCTGGCTATGCGCTT
GGCGGGGGCTCGAGGCCCGATGTTAATGACAGCACAAGCGAGGACCCCTCGTACCAGCAG
CAGGCGGCCGTGCCCCTGGCTAGCGAGACCCACGGGGGCGAGGACGTGGCGGTGTTCGCG
CGCGGCCCGCAGGCGCACCTGGTGCACGGCGTGCAGGAGGAGACCTTCGTGGCGCACATC
ATGGCCTTTGCGGGCTGCGTGGAGCCCTACACCGACTGCAATCTGCCAGCCCCCACCACC
GCCACCAGCATCCCCGACGCCGCGCACCTGGCGGCCAGCCCGCCTCCACTGGCGCTGCTG
GCTGGGGCGATGCTGCTGCTGCTGGCGCCCACCTTGTACTAA
Enzyme 64 GenBank Gene ID BC149968 Link Image
Enzyme 64 GeneCard ID LOC100125266 Link Image
Enzyme 64 GenAtlas ID Not Available
Enzyme 64 HGNC ID Not Available
Enzyme 64 Chromosome Location Not Available
Enzyme 64 Locus Not Available
Enzyme 64 SNPs SNPJam Report Link Image
Enzyme 64 General References Not Available
Enzyme 64 Metabolite References Not Available
Enzyme 65 [top]
Enzyme 65 ID 199
Enzyme 65 Name Cell division protein kinase 9
Enzyme 65 Synonyms
  1. Cyclin-dependent kinase 9
Enzyme 65 Gene Name CDK9
Enzyme 65 Protein Sequence >Cell division protein kinase 9
MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDKYELFEKVELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF
Enzyme 65 Number of Residues 372
Enzyme 65 Molecular Weight 42747.2
Enzyme 65 Theoretical pI 9.22
Enzyme 65 GO Classification
Function
Process
Component
Enzyme 65 General Function Involved in ATP binding
Enzyme 65 Specific Function Member of the cyclin-dependent kinase pair (CDK9/cyclin- T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro
Enzyme 65 Pathways Not Available
Enzyme 65 Reactions Not Available
Enzyme 65 Pfam Domain Function
Enzyme 65 Signals
  • None
Enzyme 65 Transmembrane Regions
  • None
Enzyme 65 Essentiality Not Available
Enzyme 65 GenBank ID Protein 59857679 Link Image
Enzyme 65 UniProtKB/Swiss-Prot ID Q5EAB2 Link Image
Enzyme 65 UniProtKB/Swiss-Prot Entry Name CDK9_BOVIN Link Image
Enzyme 65 PDB ID Not Available
Enzyme 65 Cellular Location Not Available
Enzyme 65 Gene Sequence >1119 bp
ATGGCAAAGCAGTACGACTCGGTGGAGTGCCCTTTTTGTGATGAGGTGACCAAATATGAG
AAGCTCGCTAAAATCGGCCAAGGCACCTTCGGGGAGGTGTTTAAGGCAAAGCACCGCAAG
ACTGGCCAAAAGGTGGCCCTGAAGAAGGTACTGATGGAGAACGAGAAAGAGGGGTTCCCC
ATTACAGCATTGCGGGAGATCAAGATCCTCCAGCTTCTAAAACACGAGAATGTGGTCAAC
TTGATTGAGATCTGTCGAACCAAAGCTTCCCCCTATAACCGCTGCAAAGGCAGTATATAC
CTGGTGTTTGACTTCTGTGAGCATGATCTTGCTGGGCTGCTGAGCAACGTTTTAGTCAAG
TTCACACTATCTGAGATCAAGAGGGTCATGCAGATGTTGCTTAACGGCCTCTACTACATC
CATAGGAACAAGATCCTGCACCGGGACATGAAGGCGGCTAACGTGCTCATCACCCGCGAT
GGGGTTCTGAAGCTGGCGGACTTTGGGCTGGCCCGGGCCTTCAGCCTGGCCAAGAACAGC
CAGCCCAACCGCTACACCAACCGTGTGGTGACCCTCTGGTACCGGCCCCCAGAGCTGTTG
CTCGGGGAGCGGGACTACGGCCCCCCCATTGATCTGTGGGGTGCTGGGTGCATCATGGCG
GAGATGTGGACCCGCAGCCCCATCATGCAGGGCAACACGGAGCAGCACCAACTCGCCCTC
ATCAGCCAGCTCTGCGGCTCCATCACCCCCGAGGTGTGGCCAAATGTGGACAAGTACGAG
CTGTTTGAGAAAGTGGAGCTGGTCAAGGGCCAGAAGCGGAAGGTGAAGGACAGGCTGAAG
GCCTACGTGCGAGACCCCTACGCACTGGACCTCATCGACAAGCTGCTGGTGCTGGACCCC
GCCCAGCGCATCGACAGTGACGACGCCCTCAACCACGACTTCTTCTGGTCTGACCCCATG
CCCTCGGACCTCAAGGGCATGCTGTCCACCCACCTGACATCCATGTTCGAGTACCTGGCA
CCTCCACGCCGGAAGGGCAGCCAGATCACCCAGCAGTCTACCAACCAGAGCCGGAATCCC
GCCACCACCAACCAGACGGAGTTTGAGCGCGTCTTCTGA
Enzyme 65 GenBank Gene ID BT020657 Link Image
Enzyme 65 GeneCard ID CDK9 Link Image
Enzyme 65 GenAtlas ID Not Available
Enzyme 65 HGNC ID Not Available
Enzyme 65 Chromosome Location Chromosome:9
Enzyme 65 Locus 9q34.1
Enzyme 65 SNPs SNPJam Report Link Image
Enzyme 65 General References
  1. [PubMed Link Image]
Enzyme 65 Metabolite References Not Available
Enzyme 66 [top]
Enzyme 66 ID 200
Enzyme 66 Name Tyrosine-protein kinase receptor
Enzyme 66 Synonyms Not Available
Enzyme 66 Gene Name CSF1R
Enzyme 66 Protein Sequence >Tyrosine-protein kinase receptor
MGPRTLLILLVVTAWHGQGVPVIEPSGPELVVEPGTAVTLRCTSNGSVKWDGPVSPYWTL
DSDAPRSILTTNNATFLHTGTYRCTEPGDPLAGTATIHLYVKDPARPWRVLAEEVTVLEG
QDALLPCLLTDPALEAGVSLVRVRGRSVLRQTSYSFSPWYGFTIHKAKFIESQDYECSVR
VAGRVVKSLSIRLKVQKVIPGPPTLTLEPEELVRIQGETAKIVCSASDVDVNFDVFLQRG
DTKLAISQQSDFRDNRYQKVLTLELDHVGFQDAGNYTCVATNARGVHTTSMVFRVVDSAY
LNLTSEQNLLQEVAVGEKLELRVKVEAYPSLQSFNWTYEGPFFGSQPKLNFETTNNTYRY
TSKLTLPRLKPSEAGLYSFQARNARGEDTLTFELTLLYPPEVEVMWTLSSGSKALLCEAS
GYPQPNVTWVQCSSHTNRCDKTHVLVLEEPNPDVLRQEPFHKVTVQSLLTPGTLEHNRTY
ECRAQNSMGNTSGALGPISVGASMQPRDEPLFTPVLVACMSIMALLLLLLLLLFYKYKQK
PKYEVRWKIIESYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFG
LGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVIT
EYCCYGDLLNFLRRKAEAMLGPSLSPGQDPEAGTGYKNIHLEKKYIRRDSGFSSQGVDTY
VEMRPVSTSSSNDSFSEQDLDKEDGRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAAR
NVLLTSGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYG
ILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPENIYSIMQACWALEPTRRPT
FQQICSLLQEQVQVDRREQDYSNLPSSGSSSSEPEEESSSEHLTCCEQGDIAQPLLQPNN
YQFC
Enzyme 66 Number of Residues 964
Enzyme 66 Molecular Weight 107352.3
Enzyme 66 Theoretical pI 5.76
Enzyme 66 GO Classification
Function
Process
Component
Enzyme 66 General Function Involved in ATP binding
Enzyme 66 Specific Function ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Enzyme 66 Pathways Not Available
Enzyme 66 Reactions Not Available
Enzyme 66 Pfam Domain Function
Enzyme 66 Signals
  • None
Enzyme 66 Transmembrane Regions
  • None
Enzyme 66 Essentiality Not Available
Enzyme 66 GenBank ID Protein 157279365 Link Image
Enzyme 66 UniProtKB/Swiss-Prot ID A7Z067 Link Image
Enzyme 66 UniProtKB/Swiss-Prot Entry Name A7Z067_BOVIN Link Image
Enzyme 66 PDB ID Not Available
Enzyme 66 Cellular Location Not Available
Enzyme 66 Gene Sequence >2895 bp
ATGGGCCCACGGACCCTGCTGATCCTGCTGGTGGTCACAGCTTGGCATGGTCAGGGGGTC
CCAGTGATAGAGCCCAGTGGCCCTGAGCTGGTGGTGGAGCCAGGCACAGCGGTGACCTTG
CGATGTACGAGCAATGGCAGCGTGAAGTGGGATGGCCCCGTTTCCCCCTACTGGACTCTG
GACTCTGACGCCCCCAGAAGCATCCTCACCACGAACAATGCCACCTTCCTACACACGGGA
ACGTACCGCTGCACTGAGCCTGGAGACCCCCTGGCGGGCACTGCTACTATCCACCTCTAT
GTCAAAGACCCTGCTCGGCCCTGGAGGGTCCTGGCCGAGGAAGTGACGGTGTTGGAGGGT
CAGGACGCGCTGCTGCCCTGTCTGCTCACTGACCCAGCACTGGAGGCGGGCGTCTCGCTG
GTGCGGGTGCGCGGCCGGTCTGTCTTGCGCCAAACCAGCTATTCCTTCTCGCCCTGGTAC
GGCTTCACCATCCACAAGGCCAAGTTCATTGAGAGCCAGGACTACGAGTGCAGCGTTCGG
GTGGCTGGCAGGGTGGTGAAGTCCCTCAGCATCCGGCTTAAAGTTCAGAAAGTCATCCCA
GGACCGCCGACCTTGACATTGGAGCCTGAAGAGCTGGTGCGGATTCAAGGGGAGACTGCC
AAGATCGTGTGCTCAGCCAGTGACGTTGATGTCAACTTTGACGTCTTCCTTCAACGTGGA
GACACAAAACTCGCAATCTCTCAACAATCCGACTTCCGTGACAACCGTTATCAAAAAGTC
CTGACTCTCGAACTCGATCACGTAGGCTTCCAAGATGCTGGCAACTACACCTGTGTGGCC
ACCAATGCCCGGGGCGTCCACACTACCTCCATGGTCTTCCGGGTGGTAGACAGTGCCTAC
TTGAACTTAACCTCTGAGCAGAACCTCCTCCAAGAGGTGGCCGTGGGTGAAAAGCTTGAA
CTCAGAGTCAAGGTGGAGGCCTACCCAAGCCTGCAAAGTTTCAACTGGACCTATGAGGGT
CCCTTCTTTGGTTCCCAGCCCAAGCTCAACTTTGAAACCACGAACAACACATACAGATAC
ACCTCCAAGCTCACCCTGCCTCGCCTGAAGCCCTCCGAGGCCGGCCTCTACTCCTTCCAG
GCTAGAAATGCCAGAGGCGAGGACACCCTGACCTTTGAACTCACCCTCCTATACCCCCCG
GAAGTAGAAGTCATGTGGACCCTCTCCAGTGGCTCTAAAGCCCTGCTCTGTGAAGCCTCC
GGGTACCCCCAGCCCAATGTGACGTGGGTGCAGTGCAGCAGCCACACCAACAGATGTGAT
AAGACCCACGTGCTGGTCCTGGAGGAGCCGAACCCTGATGTCCTGCGCCAGGAGCCCTTC
CACAAAGTGACCGTCCAGAGCCTGCTGACCCCTGGGACCTTGGAACACAACAGGACGTAC
GAGTGCAGGGCCCAGAACAGCATGGGGAACACCTCCGGGGCGTTGGGGCCCATCTCCGTA
GGAGCCTCCATGCAGCCCCGCGATGAGCCCCTCTTCACACCGGTGCTGGTGGCCTGCATG
TCCATCATGGCCTTGCTGCTGCTGCTGCTGCTGCTGCTCTTCTACAAGTACAAGCAGAAG
CCCAAGTACGAGGTGCGCTGGAAGATCATCGAGAGCTATGAAGGCAACAGCTACACCTTC
ATCGACCCCACCCAGCTGCCCTACAATGAGAAGTGGGAGTTCCCCCGGAACAACCTGCAG
TTTGGTAAGACCCTTGGAGCCGGCGCCTTCGGGAAGGTGGTAGAGGCCACGGCTTTTGGT
CTGGGCAAGGAAGATGCTGTCCTGAAGGTGGCTGTGAAGATGCTGAAGTCCACGGCGCAT
GCTGACGAGAAGGAAGCCCTCATGTCAGAGCTGAAGATCATGAGCCACCTGGGCCAGCAC
GAGAACATAGTCAACCTCTTGGGAGCCTGTACCCACGGAGGCCCTGTCCTGGTCATCACG
GAGTACTGTTGCTATGGTGACCTGCTCAACTTTCTGCGAAGGAAGGCTGAGGCCATGCTG
GGACCCAGCCTGAGTCCAGGCCAGGATCCCGAGGCAGGCACCGGCTACAAGAACATCCAC
TTGGAAAAGAAATACATCCGCAGGGACAGCGGCTTCTCCAGCCAGGGTGTGGACACCTAT
GTGGAGATGAGACCTGTGTCCACTTCGTCGTCAAATGACTCATTCTCTGAACAAGACCTG
GACAAGGAGGACGGGCGGCCGCTGGAGCTGCGTGACCTGCTCCACTTCTCGAGCCAGGTG
GCCCAGGGCATGGCCTTTCTTGCTTCCAAGAATTGCATCCATCGGGACGTGGCGGCCAGA
AACGTGCTGCTGACCAGCGGCCACGTGGCCAAGATTGGGGACTTTGGTCTGGCTCGGGAC
ATCATGAATGACTCCAACTACATCGTTAAGGGCAACGCTCGCCTGCCCGTGAAGTGGATG
GCGCCAGAGAGCATCTTCGACTGCGTCTACACCGTTCAGAGCGACGTGTGGTCCTACGGC
ATCCTGCTCTGGGAGATCTTCTCACTCGGGCTCAACCCCTACCCTGGTATCCTGGTGAAC
AGCAAGTTCTATAAGCTGGTGAAGGATGGATACCAAATGGCTCAGCCCGCGTTTGCCCCA
GAGAACATATACAGCATCATGCAGGCCTGCTGGGCCCTGGAGCCGACGCGCAGACCCACC
TTCCAGCAGATCTGCTCCCTCCTCCAGGAGCAGGTTCAGGTGGACAGGAGAGAGCAGGAC
TACAGCAATCTGCCGAGCAGTGGCAGCAGCAGCAGCGAGCCAGAGGAGGAGAGCTCCAGC
GAACACCTGACCTGCTGTGAGCAGGGCGACATCGCCCAGCCCCTGCTGCAACCCAACAAC
TACCAGTTCTGCTGA
Enzyme 66 GenBank Gene ID BC153265 Link Image
Enzyme 66 GeneCard ID CSF1R Link Image
Enzyme 66 GenAtlas ID Not Available
Enzyme 66 HGNC ID Not Available
Enzyme 66 Chromosome Location Chromosome:5
Enzyme 66 Locus 5q33-q35
Enzyme 66 SNPs SNPJam Report Link Image
Enzyme 66 General References Not Available
Enzyme 66 Metabolite References Not Available
Enzyme 67 [top]
Enzyme 67 ID 201
Enzyme 67 Name Nucleoside-triphosphatase C1orf57 homolog
Enzyme 67 Synonyms
  1. NTPase
  2. Nucleoside triphosphate phosphohydrolase
Enzyme 67 Gene Name Not Available
Enzyme 67 Protein Sequence >Nucleoside-triphosphatase C1orf57 homolog
MARHVFLTGPPGVGKTTLIQKATEVLKSSGMPVDGFYTEEVRQGGRRIGFDVVTLSGIRG
PLSRIGSEPLPGKRECRVGQYVVDLTSFEQLALPVLRNAGASGRPGQSICVIDEVGKMEL
FSQPFIQAVRQVLSIPGTVVLGTIPVPKGKPLALVEEIRTRKDVKVFSVTKENRNHLLPE
IVTHMQSSRK
Enzyme 67 Number of Residues 190
Enzyme 67 Molecular Weight 20682.0
Enzyme 67 Theoretical pI 10.61
Enzyme 67 GO Classification
Function
Process
Component
Enzyme 67 General Function Nucleotide transport and metabolism
Enzyme 67 Specific Function Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency
Enzyme 67 Pathways Not Available
Enzyme 67 Reactions Not Available
Enzyme 67 Pfam Domain Function
Enzyme 67 Signals
  • None
Enzyme 67 Transmembrane Regions
  • None
Enzyme 67 Essentiality Not Available
Enzyme 67 GenBank ID Protein 94534925 Link Image
Enzyme 67 UniProtKB/Swiss-Prot ID Q1LZ78 Link Image
Enzyme 67 UniProtKB/Swiss-Prot Entry Name CA057_BOVIN Link Image
Enzyme 67 PDB ID Not Available
Enzyme 67 Cellular Location Not Available
Enzyme 67 Gene Sequence >573 bp
ATGGCCCGGCACGTGTTCCTGACTGGGCCCCCAGGAGTTGGAAAAACAACGCTGATCCAG
AAAGCCACTGAAGTTTTAAAGTCCTCTGGCATGCCTGTTGATGGGTTTTATACAGAAGAA
GTCAGACAGGGAGGAAGAAGAATAGGGTTTGATGTTGTCACGTTGTCTGGCATCCGAGGA
CCTTTATCCAGAATTGGGTCAGAGCCTCTGCCTGGAAAGCGTGAGTGCCGTGTAGGGCAG
TACGTGGTGGATCTGACGTCCTTTGAGCAGCTGGCGCTCCCGGTCTTGAGGAATGCAGGG
GCCAGTGGTCGCCCAGGACAGAGCATTTGTGTCATCGATGAGGTGGGGAAGATGGAGCTC
TTCAGTCAGCCATTCATCCAGGCCGTCCGCCAGGTGCTGTCCATACCGGGGACTGTGGTC
CTCGGCACCATCCCCGTACCCAAAGGAAAACCACTGGCCCTCGTGGAAGAGATCAGAACC
CGAAAGGACGTGAAGGTGTTCAGCGTAACCAAGGAGAACAGAAACCACCTTTTGCCAGAG
ATTGTGACGCACATGCAGAGCAGCCGGAAGTGA
Enzyme 67 GenBank Gene ID BC116158 Link Image
Enzyme 67 GeneCard ID Not Available
Enzyme 67 GenAtlas ID Not Available
Enzyme 67 HGNC ID Not Available
Enzyme 67 Chromosome Location Not Available
Enzyme 67 Locus Not Available
Enzyme 67 SNPs SNPJam Report Link Image
Enzyme 67 General References Not Available
Enzyme 67 Metabolite References Not Available
Enzyme 68 [top]
Enzyme 68 ID 202
Enzyme 68 Name Beta-adrenergic receptor kinase 1
Enzyme 68 Synonyms
  1. Beta-ARK-1
  2. G-protein-coupled receptor kinase 2
Enzyme 68 Gene Name ADRBK1
Enzyme 68 Protein Sequence >Beta-adrenergic receptor kinase 1
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
QKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLAC
SHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
KTKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
LTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQR
VPKMKNKPRSPVVELSKVPLIQRGSANGL
Enzyme 68 Number of Residues 689
Enzyme 68 Molecular Weight 79646.2
Enzyme 68 Theoretical pI 7.29
Enzyme 68 GO Classification
Function
Process
Component
Enzyme 68 General Function Involved in ATP binding
Enzyme 68 Specific Function Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them
Enzyme 68 Pathways Not Available
Enzyme 68 Reactions Not Available
Enzyme 68 Pfam Domain Function
Enzyme 68 Signals
  • None
Enzyme 68 Transmembrane Regions
  • None
Enzyme 68 Essentiality Not Available
Enzyme 68 GenBank ID Protein 162684 Link Image
Enzyme 68 UniProtKB/Swiss-Prot ID P21146 Link Image
Enzyme 68 UniProtKB/Swiss-Prot Entry Name ARBK1_BOVIN Link Image
Enzyme 68 PDB ID 1OMW Link Image
Enzyme 68 PDB File Show
Enzyme 68 3D Structure
Enzyme 68 Cellular Location Not Available
Enzyme 68 Gene Sequence >2070 bp
ATGGCGGACCTGGAGGCGGTGCTGGCCGACGTGAGCTACCTGATGGCCATGGAGAAGAGC
AAGGCCACGCCGGCGGCGCGCGCCAGCAAGAAGATCCTGCTGCCCGAGCCCAGCATCCGC
AGCGTCATGCAGAAGTACCTGGAGGACCGGGGCGAGGTGACTTTTGAGAAGATCTTCTCC
CAGAAGCTGGGGTACCTGCTTTTCCGAGACTTCTGCCTGAAGCACCTGGAGGAGGCCAAG
CCCTTGGTAGAGTTCTACGAGGAGATCAAGAAATACGAGAAGCTGGAGACAGAGGAGGAG
CGCCTGGTCTGCAGCCGAGAGATCTTCGACACGTACATCATGAAGGAGCTGCTGGCCTGC
TCACATCCTTTCTCGAAGAGCGCCATTGAGCACGTCCAGGGCCATCTGGTGAAGAAGCAG
GTGCCTCCGGATCTCTTCCAGCCATATATTGAAGAAATTTGCCAGAACCTCCGAGGAGAC
GTGTTCCAGAAATTCATCGAGAGCGATAAATTCACACGATTTTGCCAGTGGAAGAATGTA
GAGCTCAACATCCACCTGACCATGAACGACTTCAGTGTGCACCGCATCATCGGGCGAGGC
GGCTTCGGTGAGGTCTACGGCTGCCGGAAGGCCGACACGGGCAAGATGTACGCCATGAAG
TGTCTGGACAAGAAGCGCATCAAGATGAAGCAAGGGGAGACTCTGGCCCTGAATGAGCGC
ATCATGCTGTCGCTCGTCAGCACCGGGGACTGCCCGTTCATCGTCTGCATGTCATACGCC
TTCCACACACCGGACAAGCTCAGCTTCATCCTGGATCTCATGAACGGCGGGGACCTGCAC
TACCACCTGTCCCAGCACGGGGTCTTCTCCGAGGCCGACATGCGTTTCTACGCCGCCGAG
ATCATCCTGGGCCTGGAGCACATGCACAACCGCTTCGTGGTCTACCGGGACCTGAAGCCG
GCCAACATCCTGCTGGACGAGCACGGCCACGTGCGCATCTCAGACCTGGGCCTGGCCTGT
GACTTCTCCAAGAAGAAGCCTCACGCCAGTGTGGGCACCCACGGGTACATGGCTCCCGAG
GTTCTACAGAAGGGTGTGGCCTACGACAGCAGCGCCGACTGGTTCTCCCTGGGCTGCATG
CTCTTCAAGCTGCTGCGAGGGCATAGCCCTTTCCGGCAGCACAAGACCAAAGACAAGCAT
GAGATCGACAGAATGACATTGACAATGGCTGTGGAGCTGCCTGACTCCTTCTCCCCTGAG
CTCCGCTCCTTGCTGGAGGGGCTGCTGCAGAGGGATGTCAACCGGAGGCTAGGCTGCCTG
GGCCGAGGGGCCCAGGAGGTGAAGGAGAGCCCCTTCTTCCGTTCCCTGGACTGGCAGATG
GTCTTTTTACAAAAGTACCCTCCCCCGTTGATCCCCCCACGAGGGGAGGTGAATGCAGCC
GACGCCTTTGACATTGGCTCCTTCGATGAGGAGGACACAAAAGGAATCAAGCTACTGGAC
AGTGACCAGGAGCTCTACCGCAACTTCCCCCTGACCATCTCGGAGCGGTGGCAGCAGGAG
GTAGCAGAGACTGTCTTTGACACCATCAATGCTGAGACGGACCGGCTGGAGGCCCGCAAG
AAAACCAAAAACAAGCAGTTGGGCCACGAGGAAGACTACGCCCTGGGCAAGGACTGCATC
ATGCATGGCTACATGTCCAAGATGGGCAACCCCTTCCTGACCCAGTGGCAGCGGCGGTAC
TTCTACCTGTTCCCTAACCGGCTCGAGTGGCGGGGCGAGGGCGAGGCCCCGCAGAGCCTG
CTGACCATGGAGGAGATCCAGTCGGTGGAGGAGACGCAGATCAAGGAGCGAAAGTGCCTC
CTCCTCAAGATCCGAGGTGGCAAGCAGTTTGTCCTGCAGTGCGATAGTGACCCAGAGCTG
GTGCAGTGGAAGAAGGAGCTTCGAGACGCCTACCGCGAGGCCCAGCAGCTAGTGCAGCGG
GTGCCCAAGATGAAGAACAAGCCGCGCTCGCCCGTCGTGGAGCTGAGCAAGGTGCCACTG
ATCCAGCGCGGCAGTGCCAACGGCCTCTGA
Enzyme 68 GenBank Gene ID M34019 Link Image
Enzyme 68 GeneCard ID ADRBK1 Link Image
Enzyme 68 GenAtlas ID Not Available
Enzyme 68 HGNC ID Not Available
Enzyme 68 Chromosome Location Chromosome:1
Enzyme 68 Locus 11q13.1
Enzyme 68 SNPs SNPJam Report Link Image
Enzyme 68 General References
  1. [PubMed Link Image]
Enzyme 68 Metabolite References Not Available
Enzyme 69 [top]
Enzyme 69 ID 203
Enzyme 69 Name Tyrosine-protein kinase CSK
Enzyme 69 Synonyms
  1. C-SRC kinase
Enzyme 69 Gene Name CSK
Enzyme 69 Protein Sequence >Tyrosine-protein kinase CSK
MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGII
PANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLCPPETGLFLVRESTNYPGDYTLCV
SCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQ
DEFFRSGWALNMKDLKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVM
TQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCE
AMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALRE
KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMK
NCWHLDAATRPSFLQLREQLERIKTHELHL
Enzyme 69 Number of Residues 450
Enzyme 69 Molecular Weight 50632.9
Enzyme 69 Theoretical pI 7.22
Enzyme 69 GO Classification
Function
Process
Component
Enzyme 69 General Function Involved in ATP binding
Enzyme 69 Specific Function Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases
Enzyme 69 Pathways Not Available
Enzyme 69 Reactions Not Available
Enzyme 69 Pfam Domain Function
Enzyme 69 Signals
  • None
Enzyme 69 Transmembrane Regions
  • None
Enzyme 69 Essentiality Not Available
Enzyme 69 GenBank ID Protein 111307576 Link Image
Enzyme 69 UniProtKB/Swiss-Prot ID Q0VBZ0 Link Image
Enzyme 69 UniProtKB/Swiss-Prot Entry Name CSK_BOVIN Link Image
Enzyme 69 PDB ID 1K9A Link Image
Enzyme 69 PDB File Show
Enzyme 69 3D Structure
Enzyme 69 Cellular Location Not Available
Enzyme 69 Gene Sequence >1353 bp
ATGTCAGCAATTCAGGCTGCCTGGCCATCCGGTACAGAATGTATTGCCAAGTACAACTTT
CACGGCACTGCTGAGCAAGACCTTCCCTTCTGCAAAGGAGATGTGCTCACCATTGTGGCT
GTCACCAAGGACCCCAATTGGTACAAAGCCAAGAACAAGGTGGGCCGTGAGGGCATCATC
CCAGCCAACTATGTCCAGAAGCGGGAGGGTGTGAAGGCAGGCACCAAGCTCAGCCTCATG
CCCTGGTTCCATGGCAAGATCACGCGGGAACAGGCAGAGCGGCTCCTGTGCCCACCGGAG
ACAGGCCTGTTCCTGGTGCGGGAGAGCACCAACTACCCCGGGGACTACACGCTGTGCGTG
AGCTGTGATGGCAAGGTGGAGCATTACCGCATCATGTACCACGCCAGCAAGCTCAGCATC
GATGAAGAGGTGTACTTTGAGAACCTCATGCAGCTGGTGGAGCACTACACCTCAGATGCA
GATGGCCTCTGTACTCGCCTCATCAAGCCAAAGGTCATGGAGGGCACCGTGGCCGCCCAG
GATGAGTTCTTCCGCAGTGGCTGGGCGCTGAACATGAAGGACCTGAAGCTGCTGCAGACC
ATAGGGAAGGGGGAGTTTGGAGACGTGATGCTGGGTGACTACCGAGGGAACAAAGTCGCT
GTCAAGTGCATTAAGAACGATGCCACTGCACAGGCCTTCCTGGCTGAAGCCTCCGTCATG
ACGCAACTCCGGCATAGCAACCTGGTACAGCTTCTGGGCGTGATCGTAGAGGAGAAGAGC
GGGCTGTACATCGTTACCGAGTACATGGCCAAGGGGAGTCTAGTGGACTACCTGCGGTCT
CGGGGTCGGTCGGTGCTTGGCGGAGACTGTCTCCTCAAGTTCTCACTAGACGTCTGTGAG
GCCATGGAATACCTGGAGGGCAACAACTTCGTGCATCGGGATCTGGCTGCCCGCAACGTG
CTGGTGTCTGAGGACAATGTGGCCAAGGTCAGCGACTTCGGCCTCACCAAGGAGGCCTCC
AGCACCCAGGACACGGGCAAGCTGCCGGTCAAGTGGACAGCCCCCGAGGCCCTAAGAGAG
AAGAAATTCTCCACCAAGTCTGATGTGTGGAGTTTCGGGATCCTTCTCTGGGAAATCTAC
TCTTTCGGGCGAGTGCCTTATCCAAGAATTCCCCTGAAGGACGTCGTCCCGCGGGTGGAG
AAGGGCTACAAGATGGATGCCCCTGACGGCTGCCCACCTGCAGTCTACGAGGTCATGAAG
AACTGCTGGCACCTGGATGCCGCCACGCGGCCCTCCTTCCTGCAGCTCCGCGAGCAGCTC
GAGCGCATCAAGACCCACGAGCTGCACCTGTGA
Enzyme 69 GenBank Gene ID BC120437 Link Image
Enzyme 69 GeneCard ID CSK Link Image
Enzyme 69 GenAtlas ID Not Available
Enzyme 69 HGNC ID Not Available
Enzyme 69 Chromosome Location Chromosome:1
Enzyme 69 Locus 15q23-q25
Enzyme 69 SNPs SNPJam Report Link Image
Enzyme 69 General References Not Available
Enzyme 69 Metabolite References Not Available
Enzyme 70 [top]
Enzyme 70 ID 204
Enzyme 70 Name Acetyl-CoA carboxylase 1
Enzyme 70 Synonyms
  1. ACC-alpha
  2. Biotin carboxylase
Enzyme 70 Gene Name ACACA
Enzyme 70 Protein Sequence >Acetyl-CoA carboxylase 1
MDEPSSLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLS
DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLCVDWHENDFSKRILNVPQELYEKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLARMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIGTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LTAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDV
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTRKNLLVTMLIDQLCGRGPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRLNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDSLAAMFREFTQQNKATLV
EHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ
LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE
YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG
SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA
YGDKQGPLHGMLINTPYVTKDQLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSSQA
FLPPPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPDGRDIIVI
GNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVD
PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS
GMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR
EVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVYSSVPLLNSKDPID
RVIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG
IPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL
MVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTI
NPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSVAE
RKELESKLKEREEFLLPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR
RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE
EDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILST
MDSPST
Enzyme 70 Number of Residues 2346
Enzyme 70 Molecular Weight 265300.6
Enzyme 70 Theoretical pI 6.35
Enzyme 70 GO Classification
Function
Process
Component
Enzyme 70 General Function Lipid transport and metabolism
Enzyme 70 Specific Function Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions:biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase
Enzyme 70 Pathways
  • Lipid metabolism
  • malonyl-CoA biosynthesis
  • malonyl-CoA from acetyl-CoA:step 1/1
Enzyme 70 Reactions Not Available
Enzyme 70 Pfam Domain Function
Enzyme 70 Signals
  • None
Enzyme 70 Transmembrane Regions
  • None
Enzyme 70 Essentiality Not Available
Enzyme 70 GenBank ID Protein 6006405 Link Image
Enzyme 70 UniProtKB/Swiss-Prot ID Q9TTS3 Link Image
Enzyme 70 UniProtKB/Swiss-Prot Entry Name ACACA_BOVIN Link Image
Enzyme 70 PDB ID Not Available
Enzyme 70 Cellular Location Not Available
Enzyme 70 Gene Sequence Not Available
Enzyme 70 GenBank Gene ID AJ132890 Link Image
Enzyme 70 GeneCard ID ACACA Link Image
Enzyme 70 GenAtlas ID Not Available
Enzyme 70 HGNC ID Not Available
Enzyme 70 Chromosome Location Chromosome:1
Enzyme 70 Locus 17q21
Enzyme 70 SNPs SNPJam Report Link Image
Enzyme 70 General References
  1. [PubMed Link Image]
Enzyme 70 Metabolite References Not Available
Enzyme 71 [top]
Enzyme 71 ID 205
Enzyme 71 Name Activin receptor type-1
Enzyme 71 Synonyms
  1. Activin receptor type I
  2. ACTR-I
  3. Serine/threonine-protein kinase receptor R1
  4. SKR1
Enzyme 71 Gene Name ACVR1
Enzyme 71 Protein Sequence >Activin receptor type-1
MVDGVMILPVLVMIAFPFPSMEDEKPKVNPKLYMCVCEGLSCGDEAHCEGQQCFSSLSIN
DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
NPSARLTALRIKKTLTKIDNSLDKLKTDC
Enzyme 71 Number of Residues 509
Enzyme 71 Molecular Weight 57189.5
Enzyme 71 Theoretical pI 7.36
Enzyme 71 GO Classification
Function
Process
Component
Enzyme 71 General Function Involved in activin receptor activity, type I
Enzyme 71 Specific Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May also bind activin
Enzyme 71 Pathways Not Available
Enzyme 71 Reactions Not Available
Enzyme 71 Pfam Domain Function
Enzyme 71 Signals
  • 1-20
Enzyme 71 Transmembrane Regions
  • 124-146
Enzyme 71 Essentiality Not Available
Enzyme 71 GenBank ID Protein 1381584 Link Image
Enzyme 71 UniProtKB/Swiss-Prot ID Q28041 Link Image
Enzyme 71 UniProtKB/Swiss-Prot Entry Name ACVR1_BOVIN Link Image
Enzyme 71 PDB ID Not Available
Enzyme 71 Cellular Location Not Available
Enzyme 71 Gene Sequence >1530 bp
ATGGTGGATGGAGTGATGATTCTTCCTGTGCTCGTGATGATTGCTTTCCCTTTCCCTAGT
ATGGAAGATGAGAAGCCCAAGGTAAACCCCAAGCTTTACATGTGTGTGTGTGAAGGCCTC
TCCTGTGGGGATGAGGCCCACTGTGAAGGCCAGCAGTGCTTTTCCTCGCTGAGCATAAAT
GATGGCTTCCACGTCTACCAGAAAGGCTGCTTCCAGGTCTACGAGCAGGGGAAGATGACC
TGTAAGACCCCGCCGTCACCTGGCCAGGCTGTGGAGTGCTGCCAAGGGGACTGGTGTAAC
AGGAACATCACGGCCCAGCTGCCTACTAAAGGGAAATCTTTTCCTGGAACACAGAATTTC
CACTTGGAGGTTGGCCTCATCATTTTGTCTGTAGTGTTCGCAGTATGCCTTCTAGCCTGC
CTATTGGGAGTTGCTCTCCGAAAATTTAAAAGGCGCAATCAAGAACGCCTCAACCCCAGA
GATGTGGAATATGGCACCATTGAAGGACTCATCACCACCAACGTTGGAGACAGCACTTTA
GCAGATTTATTGGATCATTCATGTACATCGGGAAGCGGCTCTGGCCTTCCTTTTCTGGTA
CAGAGAACAGTGGCCCGTCAGATCACACTGCTGGAGTGTGTTGGGAAGGGCAGGTATGGC
GAGGTGTGGAGGGGCAGCTGGCAAGGGGAGAACGTCGCTGTGAAGATCTTTTCCTCCCGG
GATGAGAAGTCGTGGTTTAGGGAAACAGAATTGTACAACACTGTGATGCTGAGGCATGAA
AATATCTTAGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACACAGTTGTGG
TTGATCACACATTATCATGAAATGGGATCGCTGTACGACTACCTTCAGCTTACTACTCTG
GATACAGTGAGCTGCCTGAGAATAGTGCTGTCCATAGCGAGCGGTCTCGCACATTTGCAC
ATAGAGATCTTTGGGACCCAAGGGAAACCGGCCATTGCTCACCGAGATCTAAAAAGCAAA
AACATCCTGGTTAAGAAGAATGGACAGTGTTGCATAGCAGATTTGGGCCTGGCAGTCATG
CATTCCCAGAGCACCAATCAGCTCGATGTGGGGAACAACCCCCGTGTGGGCACCAAACGC
TACATGGCCCCCGAAGTTCTTGATGAAACTATCCAGGTGGATTGTTTCGATTCTTACAAG
AGAGTCGATATTTGGGCCTTTGGACTTGTCTTGTGGGAGGTGGCCAGGCGGATGGTGAGC
AATGGTATTGTGGAGGATTACAAGCCACCATTCTATGATGTGGTTCCCAATGACCCAAGT
TTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAGAGGCCTAACATACCCAACAGA
TGGTTCTCAGACCCGACATTAACCTCCCTGGCCAAGCTGATGAAAGAATGCTGGTATCAA
AATCCATCTGCCAGACTCACAGCCCTGCGTATCAAAAAGACTTTGACCAAAATTGATAAT
TCCCTAGACAAATTGAAAACTGACTGTTGA
Enzyme 71 GenBank Gene ID U58095 Link Image
Enzyme 71 GeneCard ID ACVR1 Link Image
Enzyme 71 GenAtlas ID Not Available
Enzyme 71 HGNC ID Not Available
Enzyme 71 Chromosome Location Chromosome:2
Enzyme 71 Locus 2q23-q24
Enzyme 71 SNPs SNPJam Report Link Image
Enzyme 71 General References Not Available
Enzyme 71 Metabolite References Not Available
Enzyme 72 [top]
Enzyme 72 ID 206
Enzyme 72 Name Dual specificity protein phosphatase 6
Enzyme 72 Synonyms Not Available
Enzyme 72 Gene Name DUSP6
Enzyme 72 Protein Sequence >Dual specificity protein phosphatase 6
MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGSLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPTQ
QLYFTTPSNQNVYQVDSLQST
Enzyme 72 Number of Residues 381
Enzyme 72 Molecular Weight 42306.3
Enzyme 72 Theoretical pI 4.50
Enzyme 72 GO Classification
Function
Process
Component
Enzyme 72 General Function Signal transduction mechanisms
Enzyme 72 Specific Function Inactivates MAP kinases. Has a specificity for the ERK family
Enzyme 72 Pathways Not Available
Enzyme 72 Reactions Not Available
Enzyme 72 Pfam Domain Function
Enzyme 72 Signals
  • None
Enzyme 72 Transmembrane Regions
  • None
Enzyme 72 Essentiality Not Available
Enzyme 72 GenBank ID Protein 95768752 Link Image
Enzyme 72 UniProtKB/Swiss-Prot ID Q2KJ36 Link Image
Enzyme 72 UniProtKB/Swiss-Prot Entry Name DUS6_BOVIN Link Image
Enzyme 72 PDB ID 1HZM Link Image
Enzyme 72 PDB File Show
Enzyme 72 3D Structure
Enzyme 72 Cellular Location Not Available
Enzyme 72 Gene Sequence >1146 bp
ATGATAGATACGCTCAGACCCGTGCCCTTCGCGTCGGAAATGGCGATCAGCAAGACGGTG
GCGTGGCTCAACGAGCAGCTGGAGCTGGGCAACGAGCGGCTGCTGTTGATGGACTGCCGG
CCGCAGGAGCTGTACGAGTCGTCCCACATCGAGTCCGCCATCAACGTGGCCATTCCAGGG
ATCATGCTGCGGCGCCTGCAGAAGGGCAGCCTGCCGGTGCGCGCGCTATTCACGCGCGGC
GAGGACCGGGACCGCTTCACCCGGCGCTGCGGCACCGATACCGTGGTGCTCTACGATGAG
AGCAGCAGCGACTGGAACGAGAATACGGGCGGCGAGTCGGTGCTCGGGCTGCTGCTCAAG
AAGCTCAAGGACGAGGGATGCCGGGCGTTCTACCTGGAAGGTGGTTTCAGTAAGTTCCAA
GCCGAGTTCGCCCTGCACTGCGAGACCAATCTAGACGGCTCGTGTAGCAGCAGCTCGCCA
CCGTTGCCAGTGCTGGGGCTCGGGGGCCTGCGGATCAGCTCCGACTCCTCCTCGGACATT
GAGTCTGACCTTGACCGAGACCCCAATAGTGCAACGGACTCGGATGGCAGCCCGCTGTCC
AACAGTCAGCCTTCTTTCCCTGTGGAGATCTTGCCCTTCCTCTATTTGGGCTGTGCCAAG
GACTCCACCAACCTGGACGTGTTGGAGGAGTTTGGCATCAAGTACATATTGAACGTCACC
CCCAACTTGCCGAATCTCTTTGAGAATGCAGGAGAGTTCAAATACAAGCAGATCCCCATC
TCGGATCACTGGAGCCAAAACCTGTCCCAGTTTTTCCCTGAGGCCATTTCTTTCATAGAT
GAAGCCCGGGGCAAAAACTGTGGCGTCCTGGTGCATTGCTTAGCTGGCATCAGCCGCTCG
GTCACTGTGACTGTGGCTTACCTTATGCAGAAGCTCAATCTGTCGATGAACGATGCTTAT
GACATTGTGAAGATGAAGAAATCCAACATCTCCCCCAACTTCAACTTCATGGGCCAGCTG
CTGGACTTCGAGAGGACGCTGGGACTGAGCAGCCCCTGTGACAACCGCGTCCCCACACAG
CAGCTCTATTTCACCACCCCCTCCAACCAGAATGTCTACCAGGTGGACTCTCTGCAATCC
ACGTGA
Enzyme 72 GenBank Gene ID BT025424 Link Image
Enzyme 72 GeneCard ID DUSP6 Link Image
Enzyme 72 GenAtlas ID Not Available
Enzyme 72 HGNC ID Not Available
Enzyme 72 Chromosome Location Chromosome:1
Enzyme 72 Locus 12q22-q23
Enzyme 72 SNPs SNPJam Report Link Image
Enzyme 72 General References
  1. [PubMed Link Image]
Enzyme 72 Metabolite References Not Available
Enzyme 73 [top]
Enzyme 73 ID 207
Enzyme 73 Name Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Enzyme 73 Synonyms
  1. SERCA1
  2. Calcium pump 1
  3. Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform
  4. SR Ca(2+)-ATPase 1
  5. Endoplasmic reticulum class 1/2 Ca(2+) ATPase
Enzyme 73 Gene Name ATP2A1
Enzyme 73 Protein Sequence >Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
MEAAHSKTTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVLEQFEDL
LVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILTIKSTTLRVDQSIL
TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKAIGIVATTGVGTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDRIDGDLCLLNEFSVTGSTYAPEGEVLKNDKPVRSGQYDGLVELATICALC
NDSSLDFNETKGIYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPV
KEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSTKFMEYETDLTFVGVVGMLD
PPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEDVADRAYTGREFDDL
PLAEQREACRRACCFARVEPTHKSKIVEYLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRTPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFLYAEDGPHVTYSQLTHFMKCSEHSPDFEGVDCEVFEAPQPMTMAL
SVLVTIEMCNALNSLSENQSLVRMPPWVNIWLVGSIGLSMSLHFLILYVDPLPMIFKLQA
LDLYHWLMVLKISLPVIGLDEILKFVARNYLEG
Enzyme 73 Number of Residues 993
Enzyme 73 Molecular Weight 109289.4
Enzyme 73 Theoretical pI 4.93
Enzyme 73 GO Classification
Function
Process
Component
Enzyme 73 General Function Inorganic ion transport and metabolism
Enzyme 73 Specific Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction
Enzyme 73 Pathways Not Available
Enzyme 73 Reactions Not Available
Enzyme 73 Pfam Domain Function
Enzyme 73 Signals
  • None
Enzyme 73 Transmembrane Regions
  • 49-69 90-110 254-273 296-313 757-776 787-807 828-850 897-916 930-948 964-984
Enzyme 73 Essentiality Not Available
Enzyme 73 GenBank ID Protein 111304645 Link Image
Enzyme 73 UniProtKB/Swiss-Prot ID Q0VCY0 Link Image
Enzyme 73 UniProtKB/Swiss-Prot Entry Name AT2A1_BOVIN Link Image
Enzyme 73 PDB ID 1XP5 Link Image
Enzyme 73 PDB File Show
Enzyme 73 3D Structure
Enzyme 73 Cellular Location Not Available
Enzyme 73 Gene Sequence >2982 bp
ATGGAGGCTGCGCACTCCAAGACCACAGAAGAATGTTTGGCCTATTTTGGGGTGAGCGAA
ACTACAGGCCTCACCCCGGACCAAGTTAAGCGGCATCTGGAGAAATATGGCCATAATGAG
CTCCCTGCTGAGGAGGGGAAGTCCCTGTGGGAGCTGGTGTTAGAGCAGTTTGAAGACCTC
CTGGTGCGGATCCTTCTCCTGGCCGCCTGCATTTCCTTTGTGCTGGCCTGGTTTGAGGAA
GGCGAAGAGACTGTCACCGCCTTTGTTGAACCCTTTGTCATCCTCTTGATCCTCATTGCC
AATGCCATCGTGGGGGTTTGGCAGGAGCGGAATGCAGAGAATGCCATCGAGGCTCTGAAG
GAATATGAACCCGAGATGGGGAAGGTCTACCGGGCTGACCGCAAGTCAGTACAAAGGATC
AAAGCTCGGGATATTGTTCCTGGAGACATCGTGGAGGTGGCTGTGGGGGACAAGGTCCCG
GCAGATATCCGCATCCTCACCATCAAGTCTACCACCCTCCGGGTCGACCAGTCCATCCTG
ACAGGCGAGTCTGTCTCTGTCATCAAGCACACAGAACCTGTTCCCGACCCCCGAGCTGTC
AACCAGGATAAGAAGAACATGCTTTTCTCGGGCACCAACATCGCAGCCGGCAAGGCCATC
GGCATTGTGGCCACCACCGGTGTGGGCACCGAGATTGGGAAGATCCGTGACCAAATGGCC
GCCACAGAGCAGGACAAGACCCCTCTGCAGCAAAAGCTGGATGAGTTTGGGGAGCAGCTC
TCCAAGGTCATCTCCCTCATCTGCGTGGCCGTCTGGCTCATCAACATTGGCCACTTCAAC
GACCCCGTGCATGGGGGCTCCTGGATCCGTGGTGCCATCTACTACTTTAAGATCGCCGTG
GCCCTGGCTGTGGCTGCCATCCCCGAGGGCCTTCCTGCAGTCATCACCACCTGCCTGGCC
TTGGGCACCCGCCGGATGGCAAAGAAGAACGCGATCGTGAGGAGCCTGCCCTCCGTGGAG
ACTCTGGGCTGCACCTCTGTCATCTGTTCCGACAAGACGGGCACCCTCACCACCAACCAG
ATGTCTGTCTGCAAGATGTTCATCATCGACAGGATAGATGGGGACCTCTGCCTGCTGAAC
GAGTTCTCTGTCACTGGCTCCACTTACGCTCCTGAAGGAGAGGTCTTGAAGAATGATAAG
CCAGTCCGCTCAGGGCAGTATGACGGGCTGGTGGAGCTGGCCACCATTTGTGCCCTCTGC
AATGACTCCTCCTTGGACTTCAATGAGACCAAAGGTATTTATGAGAAGGTGGGAGAGGCC
ACCGAGACAGCCCTCACCACCCTGGTGGAGAAGATGAATGTATTCAACACTGAAGTGAGA
AACCTCTCGAAGGTAGAGAGGGCCAACGCCTGCAACTCGGTGATCCGCCAGCTAATGAAG
AAGGAATTCACCCTGGAGTTCTCCCGGGACCGAAAGTCCATGTCTGTCTATTGCTCTCCA
GCAAAATCCCGGGCTGCTGTGGGCAATAAGATGTTTGTCAAGGGTGCCCCTGAGGGGGTC
ATCGATCGCTGTAACTACGTGCGAGTGGGCACCACCCGGGTGCCCATGACAGGGCCGGTG
AAGGAGAAGATTCTGTCGGTGATCAAAGAGTGGGGTACTGGCCGGGACACCCTGCGCTGC
CTGGCGCTGGCCACTCGGGACACCCCCCCCAAGCGAGAGGAGATGGTCCTGGATGACTCT
ACCAAGTTCATGGAGTACGAGACGGACTTGACATTCGTTGGCGTCGTGGGCATGCTGGAC
CCGCCCCGCAAGGAGGTCATGGGCTCCATCCAACTATGCCGAGACGCTGGAATCCGAGTA
ATCATGATCACCGGAGACAACAAGGGCACGGCCATTGCCATCTGCCGACGGATTGGCATC
TTCGGGGAGAACGAGGATGTGGCTGACCGGGCCTACACTGGCCGGGAGTTCGATGACCTG
CCCCTGGCCGAGCAGCGGGAGGCCTGCCGACGCGCCTGCTGCTTCGCCCGCGTGGAGCCC
ACCCACAAGTCGAAGATCGTGGAGTATCTGCAGTCCTTCGATGAGATCACGGCGATGACA
GGTGATGGCGTCAATGACGCCCCTGCGCTGAAGAAGGCGGAAATCGGCATTGCCATGGGA
TCCGGCACTGCCGTGGCCAAGACAGCCTCTGAGATGGTGCTGGCCGACGACAACTTCTCC
ACCATTGTGGCTGCCGTGGAGGAGGGCCGGGCCATCTACAACAACATGAAGCAGTTTATC
CGCTACCTCATCTCCTCCAACGTGGGCGAGGTGGTCTGCATCTTCCTGACAGCTGCCCTG
GGGCTGCCCGAGGCCCTGATCCCTGTGCAGCTGCTGTGGGTGAACCTGGTGACCGATGGG
CTCCCAGCCACAGCCCTGGGCTTCAACCCCCCAGACCTGGACATCATGGACCGGCCCCCC
CGGACCCCCAAGGAGCCCCTCATCAGTGGCTGGCTCTTCTTCCGCTACATGGCAATTGGG
GGCTATGTGGGTGCAGCCACCGTGGGAGCAGCGGCCTGGTGGTTCCTGTATGCTGAGGAC
GGGCCTCACGTCACCTACAGCCAGCTGACTCACTTCATGAAGTGCTCGGAGCACAGCCCA
GACTTCGAGGGTGTGGACTGTGAGGTCTTCGAGGCCCCGCAGCCCATGACCATGGCCTTG
TCTGTGCTGGTCACCATCGAGATGTGCAATGCTCTCAACAGCCTGTCTGAGAATCAGTCC
CTCGTGCGGATGCCACCCTGGGTGAACATCTGGCTGGTGGGCTCCATCGGCCTCTCCATG
TCCCTCCACTTCCTCATCCTCTACGTGGACCCTCTGCCGATGATCTTCAAGCTCCAAGCC
CTGGACCTGTACCATTGGCTCATGGTCCTCAAGATCTCATTACCAGTCATTGGGCTCGAC
GAAATCCTCAAGTTCGTTGCTCGAAACTACCTGGAGGGATAA
Enzyme 73 GenBank Gene ID BC119938 Link Image
Enzyme 73 GeneCard ID ATP2A1 Link Image
Enzyme 73 GenAtlas ID Not Available
Enzyme 73 HGNC ID Not Available
Enzyme 73 Chromosome Location Chromosome:1
Enzyme 73 Locus 16p12.1
Enzyme 73 SNPs SNPJam Report Link Image
Enzyme 73 General References Not Available
Enzyme 73 Metabolite References Not Available
Enzyme 74 [top]
Enzyme 74 ID 208
Enzyme 74 Name Serine/threonine protein phosphatase
Enzyme 74 Synonyms Not Available
Enzyme 74 Gene Name PPP3CB
Enzyme 74 Protein Sequence >Serine/threonine protein phosphatase
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSF
EEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHGAQ
Enzyme 74 Number of Residues 525
Enzyme 74 Molecular Weight 59096.9
Enzyme 74 Theoretical pI 5.75
Enzyme 74 GO Classification
Function
Process
Component
Enzyme 74 General Function Involved in iron ion binding
Enzyme 74 Specific Function A phosphoprotein + H(2)O = a protein + phosphate
Enzyme 74 Pathways Not Available
Enzyme 74 Reactions Not Available
Enzyme 74 Pfam Domain Function
Enzyme 74 Signals
  • None
Enzyme 74 Transmembrane Regions
  • None
Enzyme 74 Essentiality Not Available
Enzyme 74 GenBank ID Protein 148878023 Link Image
Enzyme 74 UniProtKB/Swiss-Prot ID A6H703 Link Image
Enzyme 74 UniProtKB/Swiss-Prot Entry Name A6H703_BOVIN Link Image
Enzyme 74 PDB ID Not Available
Enzyme 74 Cellular Location Not Available
Enzyme 74 Gene Sequence >1578 bp
ATGGCCGCCCCGGAGCCGGCCCGGGCTGCACCGCCCCCACCCCCGCCCCCGCCGCCCCCT
CCCGGGGCTGACCGCGTCGTCAAAGCTGTTCCTTTCCCCCCAACACATCGCTTGACATCT
GAAGAAGTATTTGATATGGATGGGATACCCAGGGTTGATGTTCTGAAGAACCACTTAGTA
AAAGAAGGTCGGGTAGATGAAGAAATTGCACTTAGAATTATCAATGAGGGTGCTGCCATT
CTTCGGAGAGAGAAAACTATGATAGAAGTAGAGGCTCCAATTACAGTGTGTGGTGACATC
CATGGCCAATTTTTTGATCTGATGAAACTTTTTGAAGTAGGAGGATCACCTGCTAATACA
CGATACCTTTTTCTTGGTGATTATGTGGACAGAGGTTATTTTAGTATAGAGTGTGTCTTA
TATTTATGGGTCCTGAAGATTCTGTATCCAAGTACATTATTTCTTCTGAGAGGCAACCAT
GAATGCAGACACCTTACTGAATATTTTACCTTTAAGCAGGAATGTAAAATTAAATATTCA
GAAAGAGTCTATGAAGCTTGTATGGAAGCTTTTGATAGCTTGCCTCTTGCTGCACTTTTA
AACCAACAATTTCTTTGTGTTCATGGTGGACTTTCACCAGAAATACACACACTGGATGAT
ATTAGGAGATTAGATAGATTCAAAGAGCCACCTGCATTTGGACCAATGTGTGACTTGCTA
TGGTCCGATCCTTCTGAAGATTTTGGAAATGAAAAATCACAGGAACATTTTAGTCACAAT
ACAGTTCGAGGATGTTCTTATTTTTATAACTATCCAGCAGTGTGTGAATTTTTGCAAAAC
AATAATTTGTTATCGATTATTAGAGCTCATGAAGCTCAAGATGCAGGCTATAGAATGTAC
AGAAAAAGTCAAACTACAGGGTTCCCTTCATTAATAACAATTTTTTCGGCACCTAATTAC
TTAGATGTCTACAATAATAAAGCTGCTGTATTAAAGTATGAAAATAATGTGATGAATATT
CGACAGTTTAACTGTTCTCCACATCCTTATTGGTTGCCCAATTTTATGGATGTTTTCACA
TGGTCTTTACCGTTTGTTGGAGAAAAAGTGACGGAAATGTTGGTAAACGTTCTGAGTATT
TGCTCTGATGATGAACTTATGACTGAAGGCGAAGACCAGTTTGATGTAGGTTCAGCTGCA
GCCCGGAAAGAAATCATAAGAAACAAAATTCGAGCAATTGGCAAGATGGCAAGGGTCTTC
TCTGTTCTCAGGGAGGAGAGTGAAAGTGTGCTGACACTCAAGGGCCTGACTCCCACAGGG
ATGTTGCCTAGTGGAGTGTTGGCTGGAGGACGGCAGACCCTGCAAAGTGCCACAGTTGAG
GCTATTGAGGCTGAAAAAGCAATACGAGGATTCTCTCCACCACATAGAATCTGCAGTTTT
GAAGAGGCAAAGGGTTTGGATAGGATCAATGAGAGAATGCCACCCCGGAAAGATGCTGTA
CAGCAAGATGGTTTCAATTCTCTGAACACCGCACATGCCACTGAGAACCACGGGACTGGC
AACCATGGTGCCCAGTGA
Enzyme 74 GenBank Gene ID BC146063 Link Image
Enzyme 74 GeneCard ID PPP3CB Link Image
Enzyme 74 GenAtlas ID Not Available
Enzyme 74 HGNC ID Not Available
Enzyme 74 Chromosome Location Chromosome:1
Enzyme 74 Locus 10q21-q22
Enzyme 74 SNPs SNPJam Report Link Image
Enzyme 74 General References Not Available
Enzyme 74 Metabolite References Not Available
Enzyme 75 [top]
Enzyme 75 ID 209
Enzyme 75 Name Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
Enzyme 75 Synonyms
  1. Spermatogenic glyceraldehyde-3-phosphate dehydrogenase
Enzyme 75 Gene Name GAPDHS
Enzyme 75 Protein Sequence >Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
MSKRDIVLTNVTVVQLLRQPCPEPRVEAEPEPPAQPQPQPEPIKEEVPPPPPPPPAPKKV
RELIVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDLEYMVYMFKYDSTHGRYKGNVEH
KKGQLVVDNNEISVFQCKQPKEIPWKSVGSPFVVEATGVYLSLEETKAHIEAGAQRVVIC
APSPDAPMFVMGVNEKEYNPSSMKIVSNASCTTNCLAPLAKVIHERFGILEGLMTTVHSY
TATQKTVDGPSKKAWRDGRGAHQNIIPASTGAAKAVGKVIPDLKGKLTGMAFRVPTPDVS
VVDLTCRLAQPTPYSAIKDAIKAAAKGPMAGILAYTEDEVVSTDFLSDTHSSIFDAKAGI
ALNDNFVKLISWYDNEYGYSNRVVDLVRYMFSRDK
Enzyme 75 Number of Residues 395
Enzyme 75 Molecular Weight 43287.7
Enzyme 75 Theoretical pI 8.26
Enzyme 75 GO Classification
Function
Process
Component
Enzyme 75 General Function Carbohydrate transport and metabolism
Enzyme 75 Specific Function May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility
Enzyme 75 Pathways
  • Carbohydrate degradation
  • glycolysis
  • pyruvate from D- glyceraldehyde 3-phosphate:step 1/5
Enzyme 75 Reactions Not Available
Enzyme 75 Pfam Domain Function
Enzyme 75 Signals
  • None
Enzyme 75 Transmembrane Regions
  • None
Enzyme 75 Essentiality Not Available
Enzyme 75 GenBank ID Protein 86823824 Link Image
Enzyme 75 UniProtKB/Swiss-Prot ID Q2KJE5 Link Image
Enzyme 75 UniProtKB/Swiss-Prot Entry Name G3PT_BOVIN Link Image
Enzyme 75 PDB ID Not Available
Enzyme 75 Cellular Location Not Available
Enzyme 75 Gene Sequence >1188 bp
ATGTCGAAACGCGACATCGTCCTCACCAATGTCACCGTTGTCCAGCTGCTGCGACAGCCG
TGCCCTGAGCCCAGGGTTGAAGCAGAGCCTGAGCCCCCGGCCCAGCCCCAGCCCCAGCCG
GAGCCAATCAAGGAGGAAGTCCCACCACCTCCACCGCCCCCTCCTGCACCTAAGAAGGTT
CGGGAGCTGATAGTTGGCATCAATGGATTCGGACGCATCGGTCGTCTAGTGCTGCGTGCC
TGCATGGAGAAGGGCGTTAAGGTGGTAGCAGTGAACGACCCATTCATTGACCTGGAATAT
ATGGTGTATATGTTTAAGTATGACTCCACCCATGGTCGATACAAGGGGAACGTGGAACAC
AAGAAAGGACAACTGGTCGTCGATAACAATGAGATCAGTGTCTTCCAGTGCAAGCAGCCC
AAAGAAATCCCCTGGAAGTCTGTCGGGAGCCCCTTTGTGGTGGAGGCCACCGGTGTGTAC
CTGTCCTTAGAGGAAACTAAGGCCCACATCGAGGCAGGTGCCCAGCGTGTGGTCATCTGT
GCGCCCTCTCCAGATGCACCCATGTTTGTCATGGGGGTGAACGAAAAGGAATATAACCCC
AGCTCCATGAAAATCGTCAGCAATGCATCCTGCACCACCAACTGCCTGGCCCCCCTCGCC
AAGGTCATCCATGAACGATTTGGGATTCTGGAAGGGCTGATGACCACAGTCCATTCCTAC
ACGGCCACCCAGAAGACAGTGGATGGGCCATCGAAGAAAGCCTGGCGAGACGGACGGGGC
GCCCACCAGAACATCATCCCAGCCTCCACGGGGGCTGCTAAGGCCGTGGGCAAAGTCATC
CCAGACCTCAAAGGGAAGCTGACAGGAATGGCATTCCGAGTGCCAACCCCAGACGTGTCT
GTGGTGGACCTGACCTGCCGCCTGGCCCAGCCTACCCCATACTCAGCCATCAAGGACGCC
ATCAAAGCAGCAGCCAAGGGGCCCATGGCTGGCATCCTTGCCTACACGGAAGATGAGGTC
GTGTCCACGGACTTCCTTAGCGATACCCACTCGTCTATCTTCGATGCTAAGGCCGGCATC
GCGCTCAACGACAATTTCGTGAAGCTCATTTCCTGGTACGACAATGAATATGGCTACAGT
AACCGAGTGGTGGACCTCGTCCGCTACATGTTCAGCAGAGACAAGTGA
Enzyme 75 GenBank Gene ID BC105381 Link Image
Enzyme 75 GeneCard ID GAPDHS Link Image
Enzyme 75 GenAtlas ID Not Available
Enzyme 75 HGNC ID Not Available
Enzyme 75 Chromosome Location Chromosome:1
Enzyme 75 Locus 19q13.12
Enzyme 75 SNPs SNPJam Report Link Image
Enzyme 75 General References Not Available
Enzyme 75 Metabolite References Not Available
Enzyme 76 [top]
Enzyme 76 ID 210
Enzyme 76 Name Enolase-phosphatase E1
Enzyme 76 Synonyms
  1. 2,3-diketo-5-methylthio-1-phosphopentane phosphatase
  2. MASA homolog
Enzyme 76 Gene Name ENOPH1
Enzyme 76 Protein Sequence >Enolase-phosphatase E1
MVVLSVPAEVTVILLDIEGTTTPIAFVKDILFPYVKENVEEYLQAHWEEEECQQDVRLLR
KQAEEDSHLDGAVPIPAASGNGADDPQWMIQAVVDNVYWQMSLDRKTTALKQLQGHMWRA
AFKAGHMKAEFFEDVVPAVRKWREAGMKVYVYSSGSVEAQKLLFGHSTEGDILELVDGHF
DTKIGHKVESESYQKIASSIGCSTNNILFLTDVSREASAAEEAGVHVAVVVRPGNAGLTD
DEKTHFSLITSFSELYLPSST
Enzyme 76 Number of Residues 261
Enzyme 76 Molecular Weight 28929.4
Enzyme 76 Theoretical pI 4.56
Enzyme 76 GO Classification
Function
Process
Component
Enzyme 76 General Function Energy production and conversion
Enzyme 76 Specific Function Bifunctional enzyme that enolizes the substrate to form the intermediate 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate, which is then dephosphorylated to form the acireductone 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one
Enzyme 76 Pathways
  • Amino-acid biosynthesis
  • L-methionine biosynthesis via salvage pathway
  • L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate:step 4/6
Enzyme 76 Reactions Not Available
Enzyme 76 Pfam Domain Function
Enzyme 76 Signals
  • None
Enzyme 76 Transmembrane Regions
  • None
Enzyme 76 Essentiality Not Available
Enzyme 76 GenBank ID Protein 111308442 Link Image
Enzyme 76 UniProtKB/Swiss-Prot ID Q0VD27 Link Image
Enzyme 76 UniProtKB/Swiss-Prot Entry Name ENOPH_BOVIN Link Image
Enzyme 76 PDB ID Not Available
Enzyme 76 Cellular Location Not Available
Enzyme 76 Gene Sequence >786 bp
ATGGTCGTGCTTTCGGTGCCCGCCGAAGTCACTGTGATCCTGTTAGATATCGAAGGTACC
ACAACCCCGATTGCTTTCGTGAAGGACATTTTATTTCCTTACGTCAAAGAAAATGTTGAA
GAGTATCTGCAGGCACATTGGGAAGAAGAGGAGTGCCAACAGGATGTCAGGCTTTTGAGG
AAACAGGCTGAAGAGGACTCCCACCTGGATGGGGCTGTTCCAATCCCAGCAGCCTCCGGT
AATGGGGCGGACGACCCGCAGTGGATGATCCAGGCCGTGGTGGATAACGTGTACTGGCAG
ATGTCCCTGGACCGGAAGACCACGGCACTGAAGCAGCTGCAGGGCCACATGTGGAGGGCG
GCGTTCAAGGCTGGGCACATGAAAGCGGAGTTCTTTGAAGACGTGGTTCCGGCCGTCCGG
AAGTGGCGAGAGGCTGGGATGAAGGTGTATGTCTATTCTTCAGGGAGTGTGGAGGCGCAG
AAACTATTATTTGGGCATTCTACAGAGGGGGACATTCTTGAGCTTGTGGATGGTCACTTT
GATACCAAGATTGGACACAAAGTGGAGAGTGAGAGTTACCAAAAGATCGCCAGCAGCATT
GGCTGTTCAACCAACAACATCTTGTTTCTGACGGATGTTTCCCGAGAGGCCAGCGCTGCT
GAGGAGGCGGGCGTGCATGTCGCTGTGGTGGTGAGACCGGGCAACGCAGGGCTGACTGAT
GATGAGAAGACCCACTTCAGCCTCATCACGTCCTTCAGTGAACTGTACCTGCCTTCCTCA
ACCTAG
Enzyme 76 GenBank Gene ID BC119871 Link Image
Enzyme 76 GeneCard ID ENOPH1 Link Image
Enzyme 76 GenAtlas ID Not Available
Enzyme 76 HGNC ID Not Available
Enzyme 76 Chromosome Location Chromosome:4
Enzyme 76 Locus 4q21.22
Enzyme 76 SNPs SNPJam Report Link Image
Enzyme 76 General References Not Available
Enzyme 76 Metabolite References Not Available
Enzyme 77 [top]
Enzyme 77 ID 211
Enzyme 77 Name Tyrosine-protein kinase
Enzyme 77 Synonyms Not Available
Enzyme 77 Gene Name JAK1
Enzyme 77 Protein Sequence >Tyrosine-protein kinase
QDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICT
EYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVTCFEKSEVLGIQKQFKNFQIEVQKGRY
SLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLKRCCQPKPREISNLLVATKKAQEWQPV
YTMSQLSFDRILKKDITQGEHLGRGTRTHIYSGTLTDYKDDEGTSEEKRIKVILKVLDPS
HRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKSDVLT
TPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIPITVL
SRQECIERIPWIAPECVEDSKNLSVAADKWSFGTTLWEICYNGEIPLKDKTLIEKERFYE
SRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQNPDIVSEKKPTTEVDP
THFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIE
ILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQI
CKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFW
YAPECLIQCKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNT
LKEGKRLPCPPNCPDEVYQHMRKCWEFQPSNRTTFQNLIEGFEALLRSMSNI
Enzyme 77 Number of Residues 772
Enzyme 77 Molecular Weight 88605.0
Enzyme 77 Theoretical pI 6.98
Enzyme 77 GO Classification
Function
Process
Component
Enzyme 77 General Function Involved in ATP binding
Enzyme 77 Specific Function ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Enzyme 77 Pathways Not Available
Enzyme 77 Reactions Not Available
Enzyme 77 Pfam Domain Function
Enzyme 77 Signals
  • None
Enzyme 77 Transmembrane Regions
  • None
Enzyme 77 Essentiality Not Available
Enzyme 77 GenBank ID Protein 126717429 Link Image
Enzyme 77 UniProtKB/Swiss-Prot ID A3KMY9 Link Image
Enzyme 77 UniProtKB/Swiss-Prot Entry Name A3KMY9_BOVIN Link Image
Enzyme 77 PDB ID Not Available
Enzyme 77 Cellular Location Not Available
Enzyme 77 Gene Sequence Not Available
Enzyme 77 GenBank Gene ID BC133420 Link Image
Enzyme 77 GeneCard ID JAK1 Link Image
Enzyme 77 GenAtlas ID Not Available
Enzyme 77 HGNC ID Not Available
Enzyme 77 Chromosome Location Chromosome:1
Enzyme 77 Locus 1p32.3-p31.3
Enzyme 77 SNPs SNPJam Report Link Image
Enzyme 77 General References Not Available
Enzyme 77 Metabolite References Not Available